By Signaling Pathways - JAK/STAT Signaling Supplier | High Purity

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Jak-IN-10
CAS: 916741-98-5 Formula: C₂₀H₁₈FN₅O₃S Molecular Weight: 427.5

≥99%

◐ .Made to order · 8–12 wks Item #: J1304374
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IUPAC Name

5-[[5-fluoro-4-(4-prop-2-ynoxyanilino)pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide

SMILES

CC1=C(C=C(C=C1)NC2=NC=C(C(=N2)NC3=CC=C(C=C3)OCC#C)F)S(=O)(=O)N

InChIKey
YSWHPGYAPJLREH-UHFFFAOYSA-N

InChI

1S/C20H18FN5O3S/c1-3-10-29-16-8-6-14(7-9-16)24-19-17(21)12-23-20(26-19)25-15-5-4-13(2)18(11-15)30(22,27)28/h1,4-9,11-12H,10H2,2H3,(H2,22,27,28)(H2,23,show more
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N-Acetylphenoxazine
CAS: 6192-43-4 Formula: C₁₄H₁₁NO₂ Molecular Weight: 225.240

≥99%

◐ .Made to order · 8–12 wks Item #: N1061767
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IUPAC Name

1-phenoxazin-10-ylethanone

SMILES

CC(=O)N1C2=CC=CC=C2OC3=CC=CC=C31

InChIKey
MXVOQCUXOQFIHU-UHFFFAOYSA-N

InChI

1S/C14H11NO2/c1-10(16)15-11-6-2-4-8-13(11)17-14-9-5-3-7-12(14)15/h2-9H,1H3
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N-(4-chloro-2,5-dimethoxyphenyl)-5-cyclopropyl-3-isoxazolecarboxamide
CAS: 912798-42-6 PubChem CID: 6619100 Formula: C₁₅H₁₅ClN₂O₄ Molecular Weight: 322.74

≥99%

◐ .Made to order · 8–12 wks Item #: N1045189
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IUPAC Name

N-(4-chloro-2,5-dimethoxyphenyl)-5-cyclopropyl-1,2-oxazole-3-carboxamide

SMILES

COC1=CC(=C(C=C1NC(=O)C2=NOC(=C2)C3CC3)OC)Cl

InChIKey
FMWABCRYNLCXOJ-UHFFFAOYSA-N

InChI

1S/C15H15ClN2O4/c1-20-13-6-10(14(21-2)5-9(13)16)17-15(19)11-7-12(22-18-11)8-3-4-8/h5-8H,3-4H2,1-2H3,(H,17,19)
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NSC756093
CAS: 1629908-92-4 EC Number: 110-109-6 PubChem CID: 91826517 Formula: C₂₀H₁₉NO₄ Molecular Weight: 337.37

Solid Moligand™ ? ≥99%

◐ .Made to order · 8–12 wks Item #: N1004670
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IUPAC Name

4-(2-hydroxyethyl)-6-methoxy-9-phenyl-3,9-dihydrofuro[3,4-b]quinolin-1-one

SMILES

COC1=CC2=C(C=C1)C(C3=C(N2CCO)COC3=O)C4=CC=CC=C4

InChIKey
SMEJQLRLHKWIFV-UHFFFAOYSA-N

InChI

1S/C20H19NO4/c1-24-14-7-8-15-16(11-14)21(9-10-22)17-12-25-20(23)19(17)18(15)13-5-3-2-4-6-13/h2-8,11,18,22H,9-10,12H2,1H3

Synonyms
4,9-Dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenyl-furo[3,4-b]quinolin-1(3H)-one, 4-(2-Hydroxyethyl)-6-methoxy-9-pheny...
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7-(Diethylamino)-3-(5-methylbenzoxazol-2-yl)-2-benzopyrone
CAS: 34564-13-1 EC Number: 252-093-4 Formula: C₂₁H₂₀N₂O₃ Molecular Weight: 348.4

≥99%

◐ .Made to order · 8–12 wks Item #: D1320073
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IUPAC Name

7-(diethylamino)-3-(5-methyl-1,3-benzoxazol-2-yl)chromen-2-one

SMILES

CCN(CC)C1=CC2=C(C=C1)C=C(C(=O)O2)C3=NC4=C(O3)C=CC(=C4)C

InChIKey
PTAGJQADNFQMGR-UHFFFAOYSA-N

InChI

1S/C21H20N2O3/c1-4-23(5-2)15-8-7-14-11-16(21(24)26-19(14)12-15)20-22-17-10-13(3)6-9-18(17)25-20/h6-12H,4-5H2,1-3H3
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9H-Purine-9-butanoic acid, 6-amino-alpha-hydroxy-, methyl ester
CAS: 33231-14-0 Formula: C₁₀H₁₃N₅O₃ Molecular Weight: 251.240

≥99%

◐ .Made to order · 8–12 wks Item #: H1050561
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IUPAC Name

methyl 4-(6-aminopurin-9-yl)-2-hydroxybutanoate

SMILES

COC(=O)C(CCN1C=NC2=C(N=CN=C21)N)O

InChIKey
HNKGMGPCSSJYOT-UHFFFAOYSA-N

InChI

1S/C10H13N5O3/c1-18-10(17)6(16)2-3-15-5-14-7-8(11)12-4-13-9(7)15/h4-6,16H,2-3H2,1H3,(H2,11,12,13)
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Furanodienon
CAS: 24268-41-5 Formula: C₁₅H₁₈O₂ Molecular Weight: 230.30

Solid Moligand™ ? ≥99%

◐ .Made to order · 8–12 wks Item #: F1315834
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IUPAC Name

(5Z,9Z)-3,6,10-trimethyl-8,11-dihydro-7H-cyclodeca[b]furan-4-one

SMILES

CC1=CC(=O)C2=C(CC(=CCC1)C)OC=C2C

InChIKey
XVOHELPNOXGRBQ-LXQMTTSMSA-N

InChI

1S/C15H18O2/c1-10-5-4-6-11(2)8-14-15(13(16)7-10)12(3)9-17-14/h6-7,9H,4-5,8H2,1-3H3/b10-7-,11-6-

Synonyms
(5E,9E)-3,6,10-Trimethyl-7,8-dihydrocyclodeca[b]furan-4(11H)-one
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Jnj-26483327
CAS: 807640-87-5 PubChem CID: 11952856

≥99%

◐ .Made to order · 8–12 wks Item #: J1323257
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IUPAC Name

5-bromo-18-methoxy-10-methyl-16-oxa-2,10,21,23-tetrazatetracyclo[15.6.2.03,8.020,24]pentacosa-1(23),3(8),4,6,17,19,21,24-octaene

SMILES

CN1CCCCCOC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C1)C=CC(=C4)Br)OC

InChIKey
JXDYOSVKVSQGJM-UHFFFAOYSA-N

InChI

1S/C22H25BrN4O2/c1-27-8-4-3-5-9-29-21-11-17-19(12-20(21)28-2)24-14-25-22(17)26-18-10-16(23)7-6-15(18)13-27/h6-7,10-12,14H,3-5,8-9,13H2,1-2H3,(H,24,25,show more
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Mutant EGFR inhibitor
CAS: 1421373-62-7 PubChem CID: 78357783

≥99%

◐ .Made to order · 8–12 wks Item #: M1348838
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IUPAC Name

N-[5-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]-4-methoxyphenyl]prop-2-enamide

SMILES

CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=C(C(=N2)C3=CNC4=CC=CC=C43)Cl)OC

InChIKey
SUPQPCQJBYPRPC-UHFFFAOYSA-N

InChI

1S/C27H30ClN7O2/c1-6-25(36)31-21-13-22(24(37-5)14-23(21)35(4)12-11-34(2)3)32-27-30-16-19(28)26(33-27)18-15-29-20-10-8-7-9-17(18)20/h6-10,13-16,29H,1,1show more
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N-((6-(1,6-Dihydro-1-methyl-4-(methylamino)imidazo(4,5-d)pyrrolo(2,3-b)pyridin-7-yl)-2-pyridinyl)methyl)-2-methoxyacetamide
CAS: 914946-88-6 PubChem CID: 24825710

≥99%

◐ .Made to order · 8–12 wks Item #: N992863
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IUPAC Name

2-methoxy-N-[[6-[3-methyl-7-(methylamino)-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-11-yl]pyridin-2-yl]methyl]acetamide

SMILES

CNC1=C2C(=C3C=C(NC3=N1)C4=CC=CC(=N4)CNC(=O)COC)N(C=N2)C

InChIKey
ULTCRVJUAZCGPP-UHFFFAOYSA-N

InChI

1S/C19H21N7O2/c1-20-19-16-17(26(2)10-22-16)12-7-14(24-18(12)25-19)13-6-4-5-11(23-13)8-21-15(27)9-28-3/h4-7,10H,8-9H2,1-3H3,(H,21,27)(H2,20,24,25)
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Sdz-lap-977
CAS: 150779-71-8 PubChem CID: 9818362

≥98%

◐ .Made to order · 8–12 wks Item #: S1326252
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IUPAC Name

methyl 5-[2-(2,5-dimethoxyphenyl)ethyl]-2-hydroxybenzoate

SMILES

COC1=CC(=C(C=C1)OC)CCC2=CC(=C(C=C2)O)C(=O)OC

InChIKey
GZOFTOHENYHNMS-UHFFFAOYSA-N

InChI

1S/C18H20O5/c1-21-14-7-9-17(22-2)13(11-14)6-4-12-5-8-16(19)15(10-12)18(20)23-3/h5,7-11,19H,4,6H2,1-3H3
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R-348
CAS: 916742-11-5 Formula: C₂₃H₂₂FN₅O₄S Molecular Weight: 483.500

≥98%

◐ .Made to order · 8–12 wks Item #: R1013193
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IUPAC Name

N-[5-[[5-fluoro-4-(4-prop-2-ynoxyanilino)pyrimidin-2-yl]amino]-2-methylphenyl]sulfonylpropanamide

SMILES

CCC(=O)NS(=O)(=O)C1=C(C=CC(=C1)NC2=NC=C(C(=N2)NC3=CC=C(C=C3)OCC#C)F)C

InChIKey
IGLNXKVGKIFNBQ-UHFFFAOYSA-N

InChI

1S/C23H22FN5O4S/c1-4-12-33-18-10-8-16(9-11-18)26-22-19(24)14-25-23(28-22)27-17-7-6-15(3)20(13-17)34(31,32)29-21(30)5-2/h1,6-11,13-14H,5,12H2,2-3H3,(H,show more

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Frequently Asked Questions

What should I consider when selecting a JAK/STAT Signaling product?

Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.

Which JAK/STAT Signaling subcategory should I start with?

JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.

Which quality data should I check before ordering JAK/STAT Signaling?

Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

Can I search JAK/STAT Signaling by structure or CAS number?

Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

JAK/STAT signaling pages help researchers compare compounds relevant to cytokine signaling, transcriptional response, immune biology, and proliferative disease studies. Key evaluation points often include pathway node, isoform selectivity, upstream receptor context, cellular potency, biomarker response, and disease relevance. This category is useful when experiments need to connect receptor-level signaling with transcriptional outcomes across related pathway nodes. It supports both mechanism studies and discovery-stage compound selection.