Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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Products
- Debio 0617BCAS: 1332329-27-7 PubChem CID: 67328148◐ .Made to order · 8–12 wks Item #: D1428507View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-chloro-3-[2-[4-(methylcarbamoyl)anilino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]phenyl]-4-(trifluoromethyl)pyridine-2-carboxamide
- SMILES
- CNC(=O)C1=CC=C(C=C1)NC2=NC=C3CN(CCC3=N2)C4=C(C=CC(=C4)NC(=O)C5=NC=CC(=C5)C(F)(F)F)Cl
- InChIKey
- FLJSOYXRJCMRAE-UHFFFAOYSA-N
- InChI
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- Dosimertinib-dmesylateCAS: 2403760-72-3 Formula: C29H32D5N7O5S Molecular Weight: 600.74◐ .Made to order · 8–12 wks Item #: D1435735View ProductPricing & Pack Sizes
Technical Identifiers
- Dosimertinib-dCAS: 2403760-70-1 Formula: C28H28D5N7O2 Molecular Weight: 504.64◐ .Made to order · 8–12 wks Item #: D1435457View ProductPricing & Pack Sizes
Technical Identifiers
- EGA◐ .Made to order · 8–12 wks Item #: E1435766View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(E)-(4-bromophenyl)methylideneamino]-3-(2,6-dimethylphenyl)urea
- SMILES
- CC1=C(C(=CC=C1)C)NC(=O)NN=CC2=CC=C(C=C2)Br
- InChIKey
- QVNLLEFLGISSAQ-VCHYOVAHSA-N
- InChI
- 1S/C16H16BrN3O/c1-11-4-3-5-12(2)15(11)19-16(21)20-18-10-13-6-8-14(17)9-7-13/h3-10H,1-2H3,(H2,19,20,21)/b18-10+
- EGFR T790M/L858R-IN-3Formula: C28H32ClN7O2S2 Molecular Weight: 598.18◐ .Made to order · 8–12 wks Item #: E1434990View ProductPricing & Pack Sizes
Technical Identifiers
- EGFR T790M/L858R-IN-2CAS: 2955607-40-4 Formula: C28H28FN7O Molecular Weight: 497.57◐ .Made to order · 8–12 wks Item #: E1419223View ProductPricing & Pack Sizes
Technical Identifiers
- EGFR Protein Tyrosine Kinase SubstrateCAS: 945830-38-6 Formula: C48H73N11O17 Molecular Weight: 1076.16◐ .Made to order · 8–12 wks Item #: E1435465View ProductPricing & Pack Sizes
Technical Identifiers
- EGFR-IN-1 hydrochlorideCAS: 2227455-78-7 Formula: C28H31ClN6O4 Molecular Weight: 551.04◐ .Made to order · 8–12 wks Item #: E1435475View ProductPricing & Pack Sizes
Technical Identifiers
- EGFR-IN-131Formula: C26H23FN4O2S Molecular Weight: 474.55◐ .Made to order · 8–12 wks Item #: E1418130View ProductPricing & Pack Sizes
Technical Identifiers
- EGFR-IN-132CAS: 2809982-20-3 Formula: C27H31N7O3 Molecular Weight: 501.58◐ .Made to order · 8–12 wks Item #: E1434800View ProductPricing & Pack Sizes
Technical Identifiers
- EGFR-IN-133CAS: 2809982-26-9 Formula: C27H29F2N7O3 Molecular Weight: 537.56◐ .Made to order · 8–12 wks Item #: E1434698View ProductPricing & Pack Sizes
Technical Identifiers
- EGFR-IN-134Formula: C36H30N6O5 Molecular Weight: 626.66◐ .Made to order · 8–12 wks Item #: E1417411View ProductPricing & Pack Sizes
Technical Identifiers
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].