Farnesyl Transferase

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  1. Manumycin A
    CAS: 52665-74-4 PubChem CID: 6438330 Formula: C31H38N2O7 Molecular Weight: 550.64
    ◐ .Made to order · 8–12 wks Item #: M274901
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    IUPAC Name
    (2E,4E,6R)-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-show more
    SMILES
    CCCCC(C)C=C(C)C=C(C)C(=O)NC1=CC(C2C(C1=O)O2)(C=CC=CC=CC(=O)NC3=C(CCC3=O)O)O
    InChIKey
    TWWQHCKLTXDWBD-MVTGTTCWSA-N
    InChI
    1S/C31H38N2O7/c1-5-6-11-19(2)16-20(3)17-21(4)30(38)32-22-18-31(39,29-28(40-29)27(22)37)15-10-8-7-9-12-25(36)33-26-23(34)13-14-24(26)35/h7-10,12,15-19,show more
    Synonyms
    DTXSID401025744 | Manumycin A | LMFA08020185 | NCGC00163464-01 | NCGC00163464-02 | Ucfi-C | 2,4-DECADIENAMIDE, N-(5-H...
  2. BMS-214662 hydrochloride
    CAS: 195981-08-9 PubChem CID: 44189294 Formula: C25H24ClN5O2S2 Molecular Weight: 526.07
    ◐ .Made to order · 8–12 wks Item #: B168288
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    IUPAC Name
    (3R)-3-benzyl-1-(1H-imidazol-5-ylmethyl)-4-thiophen-2-ylsulfonyl-3,5-dihydro-2H-1,4-benzodiazepine-7-carbonitrile;hydrochloride
    SMILES
    C1C(N(CC2=C(N1CC3=CN=CN3)C=CC(=C2)C#N)S(=O)(=O)C4=CC=CS4)CC5=CC=CC=C5.Cl
    InChIKey
    LBPFLNDUCNNGPS-GNAFDRTKSA-N
    InChI
    1S/C25H23N5O2S2.ClH/c26-13-20-8-9-24-21(11-20)15-30(34(31,32)25-7-4-10-33-25)23(12-19-5-2-1-3-6-19)17-29(24)16-22-14-27-18-28-22;/h1-11,14,18,23H,12,1show more
    Synonyms
    195981-08-9|BMS-214662 hydrochloride|(R)-1-((1H-Imidazol-4-yl)methyl)-3-benzyl-4-(thiophen-2-ylsulfonyl)-2,3,4,5-tetr...
  3. Zaragozic Acid A, Inhibitor of squalene synthase
    CAS: 142561-96-4 PubChem CID: 6438355 Formula: C35H46O14 Molecular Weight: 690.73
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: Z329476
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    IUPAC Name
    (1S,3S,4S,5R,6R,7R)-1-[(4S,5R)-4-acetyloxy-5-methyl-3-methylidene-6-phenylhexyl]-6-[(E,4S,6S)-4,6-dimethyloct-2-enoyl]oxy-4,7-dihydroxy-2,8-dioxabicycshow more
    SMILES
    CCC(C)CC(C)C=CC(=O)OC1C(C2(OC(C(C1(O2)C(=O)O)(C(=O)O)O)C(=O)O)CCC(=C)C(C(C)CC3=CC=CC=C3)OC(=O)C)O
    InChIKey
    DFKDOZMCHOGOBR-NCSQYGPNSA-N
    InChI
    1S/C35H46O14/c1-7-19(2)17-20(3)13-14-25(37)47-28-27(38)33(48-29(30(39)40)34(45,31(41)42)35(28,49-33)32(43)44)16-15-21(4)26(46-23(6)36)22(5)18-24-11-9-show more
    Synonyms
    J-007666 | Zaragozic acid A | (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-4,7-dihyd...
  4. Lonafarnib, Protein farnesyltransferase inhibitor
    CAS: 193275-84-2 Formula: C27H31Br2ClN4O2 Molecular Weight: 638.82
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: L125407
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    IUPAC Name
    4-[2-[4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboshow more
    SMILES
    C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N
    InChIKey
    DHMTURDWPRKSOA-RUZDIDTESA-N
    InChI
    1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11Hshow more
    Synonyms
    1-Piperidinecarboxamide, 4-(2-(4-((11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-y...
  5. Alendronate sodium trihydrate
    CAS: 121268-17-5 Formula: C4H12NaNO7P2·3H2O Molecular Weight: 325.12
    ● In Stock — US warehouse, ships to EU* Item #: A115345
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    IUPAC Name
    sodium;(4-amino-1-hydroxy-1-phosphonobutyl)-hydroxyphosphinate;trihydrate
    SMILES
    C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+]
    InChIKey
    DCSBSVSZJRSITC-UHFFFAOYSA-M
    InChI
    1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
    Synonyms
    AB09896 | ALENDRONATE SODIUM HYDRATE [JAN] | ALENDRONATE SODIUM SALT TRIHYDRATE | Indium, foil, 8mm disks, thickness ...
  6. Andrastin A
    CAS: 174232-42-9 PubChem CID: 6712564 Formula: C28H38O7 Molecular Weight: 486.6
    ◐ .Made to order · 8–12 wks Item #: A275495
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    IUPAC Name
    methyl (3S,5R,8S,9R,10S,13R,14R)-3-acetyloxy-10-formyl-4,4,8,12,13,16-hexamethyl-15,17-dioxo-2,3,5,6,7,9-hexahydro-1H-cyclopenta[a]phenanthrene-14-carshow more
    SMILES
    CC1C(=O)C2(C(=CC3C(C2(C1=O)C(=O)OC)(CCC4C3(CCC(C4(C)C)OC(=O)C)C=O)C)C)C
    InChIKey
    GRBXNADBNJGZRK-GJEDHNSHSA-N
    InChI
    1S/C28H38O7/c1-15-13-19-25(6,28(23(33)34-8)22(32)16(2)21(31)26(15,28)7)11-9-18-24(4,5)20(35-17(3)30)10-12-27(18,19)14-29/h13-14,16,18-20H,9-12H2,1-8H3show more
    Synonyms
    ACon0_000842 | Andrastin A, Aspergillus fumigatus | AKOS030589737 | Q15410283 | J-010973 | Andrastin A | Methyl-3-(ac...
  7. Incadronate disodium
    CAS: 138330-18-4 Formula: C8H17NNa2O6P2 Molecular Weight: 331.15
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: I276081
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    Synonyms
    Disodium[(cycloheptylamino)-[hydroxy(oxido)phosphoryl]methyl]-hydroxyphosphinate | YM 175 | Bisphonal | YM-175 | Cima...
  8. Tipifarnib, Inhibitor of farnesyltransferase; CAAX box; beta
    CAS: 192185-72-1 Formula: C27H22Cl2N4O Molecular Weight: 489.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: T125396
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    IUPAC Name
    6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one
    SMILES
    CN1C=NC=C1C(C2=CC=C(C=C2)Cl)(C3=CC4=C(C=C3)N(C(=O)C=C4C5=CC(=CC=C5)Cl)C)N
    InChIKey
    PLHJCIYEEKOWNM-HHHXNRCGSA-N
    InChI
    1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1show more
    Synonyms
    (+)-(r)-6-[amino(4-chlorophenyl)(1-methyl-1h-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1h)-quinolinone | 6-...
  9. YM-53601
    CAS: 182959-33-7 PubChem CID: 9907532 Formula: C21H21FN2O・HCl Molecular Weight: 372.86
    ● In Stock — US warehouse, ships to EU* Item #: Y332775
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    IUPAC Name
    2-[2-(1-azabicyclo[2.2.2]octan-3-ylidene)-2-fluoroethoxy]-9H-carbazole;hydrochloride
    SMILES
    C1CN2CCC1C(=C(COC3=CC4=C(C=C3)C5=CC=CC=C5N4)F)C2.Cl
    InChIKey
    JWXYVHMBPISIJQ-UHFFFAOYSA-N
    InChI
    1S/C21H21FN2O.ClH/c22-19(18-12-24-9-7-14(18)8-10-24)13-25-15-5-6-17-16-3-1-2-4-20(16)23-21(17)11-15;/h1-6,11,14,23H,7-10,12-13H2;1H
    Synonyms
    2-[(2E)-2-(1-azabicyclo[2.2.2]oct-3-ylidene)-2-fluoroethoxy]-9H-carbazole, monohydrochloride
  10. BMS 214662, Inhibitor of farnesyltransferase; CAAX box; beta
    CAS: 195987-41-8 Formula: C25H23N5O2S2 Molecular Weight: 489.61
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: B345015
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    IUPAC Name
    (3R)-3-benzyl-1-(1H-imidazol-5-ylmethyl)-4-thiophen-2-ylsulfonyl-3,5-dihydro-2H-1,4-benzodiazepine-7-carbonitrile
    SMILES
    C1C(N(CC2=C(N1CC3=CN=CN3)C=CC(=C2)C#N)S(=O)(=O)C4=CC=CS4)CC5=CC=CC=C5
    InChIKey
    OLCWFLWEHWLBTO-HSZRJFAPSA-N
    InChI
    1S/C25H23N5O2S2/c26-13-20-8-9-24-21(11-20)15-30(34(31,32)25-7-4-10-33-25)23(12-19-5-2-1-3-6-19)17-29(24)16-22-14-27-18-28-22/h1-11,14,18,23H,12,15-17Hshow more
    Synonyms
    BMS214662 | BMS-214662 | CHEBI:167655 | BMS 214662 [WHO-DD] | DTXSID20173260 | DL-3-Amino-3-(3,4-dimethoxy-phenyl)pro...
  11. L-778123 Dihydrochloride
    CAS: 183499-56-1 PubChem CID: 22464354 Formula: C22H20ClN5O•2HCl Molecular Weight: 478.8
    ◐ .Made to order · 8–12 wks Item #: L404624
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    IUPAC Name
    4-[[5-[[4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl]imidazol-1-yl]methyl]benzonitrile;dihydrochloride
    SMILES
    C1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl.Cl.Cl
    InChIKey
    XNGJWEBJQJQXQR-UHFFFAOYSA-N
    InChI
    1S/C22H20ClN5O.2ClH/c23-19-2-1-3-20(10-19)28-9-8-26(15-22(28)29)14-21-12-25-16-27(21)13-18-6-4-17(11-24)5-7-18;;/h1-7,10,12,16H,8-9,13-15H2;2*1H
    Synonyms
    SCHEMBL7652771 | 183499-56-1 (2HCl) | L-778123 Dihydrochloride | L0337 | 4-[[5-[[4-(3-chlorophenyl)-3-oxopiperazin-1-...
  12. Alendronate sodium trihydrate
    CAS: 121268-17-5 EC Number: 601-766-4 Formula: C4H12NaNO7P2·3H2O Molecular Weight: 325.12
    10mM in Water
    ● In Stock — US warehouse, ships to EU* Item #: A420924
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    Technical Identifiers
    IUPAC Name
    sodium;(4-amino-1-hydroxy-1-phosphonobutyl)-hydroxyphosphinate;trihydrate
    SMILES
    C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.O.O.[Na+]
    InChIKey
    DCSBSVSZJRSITC-UHFFFAOYSA-M
    InChI
    1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
    Synonyms
    121268-17-5|Alendronate sodium trihydrate|Fosamax|Alendronate monosodium trihydrate|Alendronate sodium hydrate|Adrona...
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Frequently Asked Questions

What can I find under Farnesyl Transferase?
This listing collects compounds associated with Farnesyl Transferase within our Metabolic Enzyme/Protease area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Farnesyl Transferase?
Consider the reported potency of each Farnesyl Transferase compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Farnesyl Transferase compounds?
Each Farnesyl Transferase product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Farnesyl Transferase compounds by activity or structure?
Yes. Filter the Farnesyl Transferase listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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