GPR55

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  1. O-1602, Agonist of GPR18;Agonist of GPR55
    CAS: 317321-41-8 Formula: C17H22O2 Molecular Weight: 258.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% 10mg/ml in methyl acetate
    ● In Stock — US warehouse, ships to EU* Item #: O275306
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    IUPAC Name
    5-methyl-4-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]benzene-1,3-diol
    SMILES
    CC1=CC(C(CC1)C(=C)C)C2=C(C=C(C=C2C)O)O
    InChIKey
    KDZOUSULXZNDJH-LSDHHAIUSA-N
    InChI
    1S/C17H22O2/c1-10(2)14-6-5-11(3)7-15(14)17-12(4)8-13(18)9-16(17)19/h7-9,14-15,18-19H,1,5-6H2,2-4H3/t14-,15+/m0/s1
    Synonyms
    J-018524 | SR-01000946749-1 | O 1602 | Q15409358 | SCHEMBL3763279 | 5-METHYL-4-[(1R,6R)-3-METHYL-6-(1-METHYLETHENYL)-...
  2. ML 184, Agonist of GPR55
    CAS: 794572-10-4 EC Number: 885-292-5 Formula: C25H34N4O3S Molecular Weight: 470.63
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: M286886
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    IUPAC Name
    3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-pyrrolidin-1-ylbenzenesulfonamide
    SMILES
    CC1=C(C(=CC=C1)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)S(=O)(=O)N(C)C)N4CCCC4)C
    InChIKey
    VRSJAHQGJHDACS-UHFFFAOYSA-N
    InChI
    1S/C25H34N4O3S/c1-19-8-7-9-23(20(19)2)28-14-16-29(17-15-28)25(30)22-18-21(33(31,32)26(3)4)10-11-24(22)27-12-5-6-13-27/h7-11,18H,5-6,12-17H2,1-4H3
    Synonyms
    ML184 | CID-2440433 | CID 2440433 | 3-[4-(2,3-Dimethylphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-pyrrolidin-1-ylben...
  3. Arachidonylethanolamide(AEA), Channel blocker of Ca v3.1;Channel blocker of Ca v3.2;Channel blocker of Ca v3.3;Agonist of CB 1 receptor;Agonist of CB 2 receptor;Allosteric modulator of glycine receptor α1 subunit;Agonist of GPR18;Agonist of GPR55;Channel blocker of K 2P3.1;Inhibitor o
    CAS: 94421-68-8 Formula: C22H37NO2 Molecular Weight: 347.543
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A274932
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    IUPAC Name
    (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide
    SMILES
    CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCO
    InChIKey
    LGEQQWMQCRIYKG-DOFZRALJSA-N
    InChI
    1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9show more
    Synonyms
    AEA | [14C]Anandamide | AEA-D8 | NAE(20:4) | NCGC00161195-05 | 5,8,11,14-Eicosatetraenamide, N-(2-hydroxyethyl)-, (al...
  4. CID 16020046, Antagonist of GPR55
    CAS: 834903-43-4 EC Number: 806-167-3 Formula: C25H19N3O4 Molecular Weight: 425.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: C288401
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    IUPAC Name
    4-[4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoic acid
    SMILES
    CC1=CC=C(C=C1)C2=NNC3=C2C(N(C3=O)C4=CC=C(C=C4)C(=O)O)C5=CC(=CC=C5)O
    InChIKey
    VGUQVYZXABOXCX-UHFFFAOYSA-N
    InChI
    1S/C25H19N3O4/c1-14-5-7-15(8-6-14)21-20-22(27-26-21)24(30)28(18-11-9-16(10-12-18)25(31)32)23(20)17-3-2-4-19(29)13-17/h2-13,23,29H,1H3,(H,26,27)(H,31,3show more
    Synonyms
    4-[4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1,4-dihydropyrrolo[3,4-d]pyrazol-5-yl]benzoic acid | 4-[4-(3-hydroxyp...
  5. CID 16020046, Antagonist of GPR55
    CAS: 834903-43-4 EC Number: 806-167-3 Formula: C25H19N3O4 Molecular Weight: 425.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: C426162
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    IUPAC Name
    4-[4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoic acid
    SMILES
    CC1=CC=C(C=C1)C2=NNC3=C2C(N(C3=O)C4=CC=C(C=C4)C(=O)O)C5=CC(=CC=C5)O
    InChIKey
    VGUQVYZXABOXCX-UHFFFAOYSA-N
    InChI
    1S/C25H19N3O4/c1-14-5-7-15(8-6-14)21-20-22(27-26-21)24(30)28(18-11-9-16(10-12-18)25(31)32)23(20)17-3-2-4-19(29)13-17/h2-13,23,29H,1H3,(H,26,27)(H,31,3show more
    Synonyms
    4-[4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1,4-dihydropyrrolo[3,4-d]pyrazol-5-yl]benzoic acid | 4-[4-(3-hydroxyp...
  6. ML 193, Antagonist of GPR55
    CAS: 713121-80-3 Formula: C28H25N5O4S Molecular Weight: 527.59
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: M288575
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    IUPAC Name
    N-[4-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]phenyl]-6,8-dimethyl-2-pyridin-2-ylquinoline-4-carboxamide
    SMILES
    CC1=CC(=C2C(=C1)C(=CC(=N2)C3=CC=CC=N3)C(=O)NC4=CC=C(C=C4)S(=O)(=O)NC5=C(C(=NO5)C)C)C
    InChIKey
    HTSLEZOTMYUPLU-UHFFFAOYSA-N
    InChI
    1S/C28H25N5O4S/c1-16-13-17(2)26-22(14-16)23(15-25(31-26)24-7-5-6-12-29-24)27(34)30-20-8-10-21(11-9-20)38(35,36)33-28-18(3)19(4)32-37-28/h5-15,33H,1-4Hshow more
    Synonyms
    CID 1261822 | N-[4-[[(3,4-Dimethyl-5-isoxazolyl)amino]sulfonyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarbox...
  7. ML-191
    CAS: 931695-79-3 Formula: C24H25N3O3 Molecular Weight: 403.47
    ● In Stock — US warehouse, ships to EU* Item #: M333024
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    IUPAC Name
    3-[1-[1-(4-methylphenyl)cyclopropanecarbonyl]piperidin-4-yl]-5-phenyl-1,3,4-oxadiazol-2-one
    SMILES
    CC1=CC=C(C=C1)C2(CC2)C(=O)N3CCC(CC3)N4C(=O)OC(=N4)C5=CC=CC=C5
    InChIKey
    WWJKJCDOYFKZBJ-UHFFFAOYSA-N
    InChI
    1S/C24H25N3O3/c1-17-7-9-19(10-8-17)24(13-14-24)22(28)26-15-11-20(12-16-26)27-23(29)30-21(25-27)18-5-3-2-4-6-18/h2-10,20H,11-16H2,1H3
    Synonyms
    3-[1-[[1-(4-methylphenyl)cyclopropyl]-oxomethyl]-4-piperidinyl]-5-phenyl-1,3,4-oxadiazol-2-one | CID23612552 | 3-[1-[...
  8. Tocrifluor T1117, Agonist of GPR55
    CAS: 1186195-59-4 PubChem CID: 57369426 Formula: C₅₆H₅₃Cl₂N₇O₅ Molecular Weight: 974.97
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%(HPLC)
    ◐ .Made to order · 8–12 wks Item #: T287844
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    IUPAC Name
    5-[4-[4-[3-[[3',6'-bis(dimethylamino)-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carbonyl]amino]propyl]phenyl]phenyl]-1-(2,4-dichlorophenyl)-4-methyl-N-show more
    SMILES
    CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)C5=CC=C(C=C5)CCCNC(=O)C6=CC7=C(C=C6)C8(C9=C(C=C(C=C9)N(C)C)OC1=C8C=CC(=C1)N(C)C)OC7=O
    InChIKey
    RNAPRXIZPJDYPH-UHFFFAOYSA-N
    InChI
    1S/C56H53Cl2N7O5/c1-34-51(54(67)61-64-28-7-6-8-29-64)60-65(48-26-20-40(57)31-47(48)58)52(34)38-17-15-37(16-18-38)36-13-11-35(12-14-36)10-9-27-59-53(66show more
    Synonyms
    5-(4'-(3-(3',6'-Bis(dimethylamino)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxamido)propyl)-[1,1'-biphenyl]-...
  9. CID1172084, Agonist of GPR55
    CAS: 459848-10-3 PubChem CID: 1172084
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: C608554
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    IUPAC Name
    N-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]-2-[(8-methoxy-4-methyl-[1,2,4]triazolo[4,5-a]quinolin-1-yl)sulfanyl]acetamide
    SMILES
    COc1ccc2c(c1)n1c(SCC(=O)Nc3scc(n3)c3ccc(cc3)F)nnc1c(c2)C
    InChIKey
    NQAXYXKWUOWLNN-UHFFFAOYSA-N
    InChI
    1S/C23H18FN5O2S2/c1-13-9-15-5-8-17(31-2)10-19(15)29-21(13)27-28-23(29)33-12-20(30)26-22-25-18(11-32-22)14-3-6-16(24)7-4-14/h3-11H,12H2,1-2H3,(H,25,26,show more
    Synonyms
    CID 1172084
  10. CID1792197, Agonist of GPR55
    CAS: 1164479-69-9 PubChem CID: 1792197
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: C608556
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    IUPAC Name
    3-(2-methoxyphenyl)-N-[[4-(methyl-phenylsulfamoyl)phenyl]carbamothioyl]prop-2-enamide
    SMILES
    COc1ccccc1/C=C/C(=O)NC(=S)Nc1ccc(cc1)S(=O)(=O)N(c1ccccc1)C
    InChIKey
    XOMQERYBMDFBAG-SFQUDFHCSA-N
    InChI
    1S/C24H23N3O4S2/c1-27(20-9-4-3-5-10-20)33(29,30)21-15-13-19(14-16-21)25-24(32)26-23(28)17-12-18-8-6-7-11-22(18)31-2/h3-17H,1-2H3,(H2,25,26,28,32)/b17-show more
    Synonyms
    CID 1792197
  11. PSB-SB-487
    CAS: 1399049-81-0 PubChem CID: 70678101 Formula: C26H32O4 Molecular Weight: 408.53
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: P648326
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    IUPAC Name
    5-hydroxy-3-[(2-hydroxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one
    SMILES
    CCCCCCCC(C)(C)C1=CC(=C2C=C(C(=O)OC2=C1)CC3=CC=CC=C3O)O
    InChIKey
    YNWOMOUVWNKICO-UHFFFAOYSA-N
    InChI
    1S/C26H32O4/c1-4-5-6-7-10-13-26(2,3)20-16-23(28)21-15-19(25(29)30-24(21)17-20)14-18-11-8-9-12-22(18)27/h8-9,11-12,15-17,27-28H,4-7,10,13-14H2,1-3H3
    Synonyms
    5-Hydroxy-3-(2-hydroxybenzyl)-7-(2-methylnonan-2-yl)-2h-chromen-2-one
  12. ML192
    CAS: 460331-61-7 PubChem CID: 1434953 Formula: C20H22N4O2S Molecular Weight: 382.48
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: M648928
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    IUPAC Name
    furan-2-yl-[4-(2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]methanone
    SMILES
    CC1=NC(=C2C3=C(CCCC3)SC2=N1)N4CCN(CC4)C(=O)C5=CC=CO5
    InChIKey
    GDPDARVUXXOYAJ-UHFFFAOYSA-N
    InChI
    1S/C20H22N4O2S/c1-13-21-18(17-14-5-2-3-7-16(14)27-19(17)22-13)23-8-10-24(11-9-23)20(25)15-6-4-12-26-15/h4,6,12H,2-3,5,7-11H2,1H3
    Synonyms
    Furan-2-yl(4-(2-methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl)methanone | ML 192,CID-...
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Frequently Asked Questions

How is the GPR55 listing put together?
It draws on reported GPR55 annotations within GPCR/G Protein and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a GPR55 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the GPR55 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for GPR55 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For GPR55 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the GPR55 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of GPR55 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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