Guanylate Cyclase

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  1. YC-1, Activator of Guanylyl cyclase; α 1β 1;Activator of Guanylyl cyclase; α 2β 1
    CAS: 170632-47-0 PubChem CID: 5712 Formula: C19H16N2O2 Molecular Weight: 304.34
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: Y274733
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    IUPAC Name
    [5-(1-benzylindazol-3-yl)furan-2-yl]methanol
    SMILES
    C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=N2)C4=CC=C(O4)CO
    InChIKey
    OQQVFCKUDYMWGV-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2/c22-13-15-10-11-18(23-15)19-16-8-4-5-9-17(16)21(20-19)12-14-6-2-1-3-7-14/h1-11,22H,12-13H2
    Synonyms
    3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole | A907557 | YC1 | yc-1 | [5-[1-(phenylmethyl)indazol-3-yl]furan-2-yl]...
  2. Methylene blue
    CAS: 61-73-4 EC Number: 200-515-2 Formula: C16H18ClN3S Molecular Weight: 319.85
    Solid ≥70%
    ● In Stock — US warehouse, ships to EU* Item #: M134389
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    IUPAC Name
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride
    SMILES
    CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-]
    InChIKey
    CXKWCBBOMKCUKX-UHFFFAOYSA-M
    InChI
    1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1
    Synonyms
    Methylene Blue BB (Zinc Free) | Methylene Blue USP (Medicinal) | 3H-Phenothiazine, 7-(dimethylamino)-3-(methylimino)-...
  3. Methylene Blue hydrate
    CAS: 122965-43-9 Formula: C16H18ClN3S·xH2O Molecular Weight: 319.85 (anhydrous basis)
    ● In Stock — US warehouse, ships to EU* Item #: M190219
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    IUPAC Name
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;hydrate
    SMILES
    CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.[Cl-]
    InChIKey
    WQVSELLRAGBDLX-UHFFFAOYSA-M
    InChI
    1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1
    Synonyms
    UNII-O3YJW1TB3C | O3YJW1TB3C | (+/-)-5-bromo-2-aminoindane hydrobromide | E79163 | FT-0775246 | Zinc free Methylene B...
  4. Methylene blue
    CAS: 7220-79-3 EC Number: 615-731-6 Formula: C16H18ClN3S·3H2O Molecular Weight: 373.9
    Indicator ? Indicator grade — characterized dye giving a defined color change at a known transition. Use to signal pH or titration endpoints visually.
    ● In Stock — Germany Item #: M102719
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    IUPAC Name
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
    SMILES
    CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]
    InChIKey
    XQAXGZLFSSPBMK-UHFFFAOYSA-M
    InChI
    1S/C16H18N3S.ClH.3H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;;;/h5-10H,1-4H3;1H;3*1H2/q+1;;;;/p-1
    Synonyms
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate | METHYLENE BLUE [IARC] | Methylene blu...
  5. Methylene Blue trihydrate
    CAS: 7220-79-3 EC Number: 615-731-6 Formula: C16H18ClN3S·3H2O Molecular Weight: 373.9
    Solid Biological Stain ? Biological stain grade — dyes characterized for staining cells and tissues. Use in histology and microscopy where staining consistency matters. Purifed ? Purified grade — refined to remove major impurities for cleaner results. Use when crude material would introduce unwanted interference. ≥90%(HPLC)
    ● In Stock — Germany Item #: M102717
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    Technical Identifiers
    IUPAC Name
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate
    SMILES
    CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]
    InChIKey
    XQAXGZLFSSPBMK-UHFFFAOYSA-M
    InChI
    1S/C16H18N3S.ClH.3H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;;;/h5-10H,1-4H3;1H;3*1H2/q+1;;;;/p-1
    Synonyms
    [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate | METHYLENE BLUE [IARC] | Methylene blu...
  6. BAY 41-2272, Activator of Guanylyl cyclase; α 1β 1
    CAS: 256376-24-6 Formula: C20H17FN6 Molecular Weight: 360.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: B303240
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    IUPAC Name
    5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine
    SMILES
    C1CC1C2=CN=C(N=C2N)C3=NN(C4=C3C=CC=N4)CC5=CC=CC=C5F
    InChIKey
    ATOAHNRJAXSBOR-UHFFFAOYSA-N
    InChI
    1S/C20H17FN6/c21-16-6-2-1-4-13(16)11-27-20-14(5-3-9-23-20)17(26-27)19-24-10-15(12-7-8-12)18(22)25-19/h1-6,9-10,12H,7-8,11H2,(H2,22,24,25)
    Synonyms
    CCG-268161 | 5-cyclopropyl-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine | 5-Cyclopropyl-2-[...
  7. BAY 41-8543
    CAS: 256498-66-5 Formula: C21H21FN8O Molecular Weight: 420.44
    ◐ .Made to order · 8–12 wks Item #: B288616
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    IUPAC Name
    2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]-5-morpholin-4-ylpyrimidine-4,6-diamine
    SMILES
    C1COCCN1C2=C(N=C(N=C2N)C3=NN(C4=C3C=CC=N4)CC5=CC=CC=C5F)N
    InChIKey
    AQYFUZRYBJBAGZ-UHFFFAOYSA-N
    InChI
    1S/C21H21FN8O/c22-15-6-2-1-4-13(15)12-30-21-14(5-3-7-25-21)16(28-30)20-26-18(23)17(19(24)27-20)29-8-10-31-11-9-29/h1-7H,8-12H2,(H4,23,24,26,27)
    Synonyms
    AS-35182 | Q27256130 | 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-morpholinopyrimidine-4,6-diamine | b]p...
  8. Ebselen Oxide
    CAS: 104473-83-8 Formula: C13H9NO2Se Molecular Weight: 290.18
    ● In Stock — US warehouse, ships to EU* Item #: E344603
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    IUPAC Name
    1-oxo-2-phenyl-1λ4,2-benzoselenazol-3-one
    SMILES
    C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2=O
    InChIKey
    SBTLFLABILGUMK-UHFFFAOYSA-N
    InChI
    1S/C13H9NO2Se/c15-13-11-8-4-5-9-12(11)17(16)14(13)10-6-2-1-3-7-10/h1-9H
    Synonyms
    NSC639772 | NSC-639772 | 1-oxo-2-phenyl-1lambda4,2-benzoselenazol-3-one | Ebselen Oxide | 1,2-Benzisoselenazole-1,3-d...
  9. Riociguat, Soluble guanylate cyclase positive allosteric modulator
    CAS: 625115-55-1 EC Number: 641-755-1 PubChem CID: 11304743 Formula: C20H19FN8O2 Molecular Weight: 422.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: R127750
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    IUPAC Name
    methyl N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]-N-methylcarbamate
    SMILES
    CN(C1=C(N=C(N=C1N)C2=NN(C3=C2C=CC=N3)CC4=CC=CC=C4F)N)C(=O)OC
    InChIKey
    WXXSNCNJFUAIDG-UHFFFAOYSA-N
    InChI
    1S/C20H19FN8O2/c1-28(20(30)31-2)15-16(22)25-18(26-17(15)23)14-12-7-5-9-24-19(12)29(27-14)10-11-6-3-4-8-13(11)21/h3-9H,10H2,1-2H3,(H4,22,23,25,26)
    Synonyms
    AMY4218 | HMS3413M12 | Methyl 4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl(methyl)...
  10. 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one, Inhibitor of Guanylyl cyclase; α 1β 1;Inhibitor of Guanylyl cyclase; α 2β 1
    CAS: 41443-28-1 EC Number: 637-000-0 Formula: C9H5N3O2 Molecular Weight: 187.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: H133434
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    IUPAC Name
    [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one
    SMILES
    C1=CC=C2C(=C1)N=CC3=NOC(=O)N23
    InChIKey
    LZMHWZHOZLVYDL-UHFFFAOYSA-N
    InChI
    1S/C9H5N3O2/c13-9-12-7-4-2-1-3-6(7)10-5-8(12)11-14-9/h1-5H
    Synonyms
    [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | EU-0100953 | 3-METHYL(1,1'-BIPHENYL)-4-AMINE | S57V2NMV38 | O0400 | Tocris...
  11. Ataciguat, Soluble guanylate cyclase activator
    CAS: 254877-67-3 Formula: C21H19Cl2N3O6S3 Molecular Weight: 576.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A358567
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    IUPAC Name
    5-chloro-2-[(5-chlorothiophen-2-yl)sulfonylamino]-N-(4-morpholin-4-ylsulfonylphenyl)benzamide
    SMILES
    C1COCCN1S(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=C(C=CC(=C3)Cl)NS(=O)(=O)C4=CC=C(S4)Cl
    InChIKey
    PQHLRGARXNPFCF-UHFFFAOYSA-N
    InChI
    1S/C21H19Cl2N3O6S3/c22-14-1-6-18(25-34(28,29)20-8-7-19(23)33-20)17(13-14)21(27)24-15-2-4-16(5-3-15)35(30,31)26-9-11-32-12-10-26/h1-8,13,25H,9-12H2,(H,show more
    Synonyms
    Ataciguat | GTPL5141 | A911275 | HY-17500 | 5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfo...
  12. 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one, Inhibitor of Guanylyl cyclase; α 1β 1;Inhibitor of Guanylyl cyclase; α 2β 1
    CAS: 41443-28-1 EC Number: 637-000-0 Formula: C9H5N3O2 Molecular Weight: 187.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: H423879
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    Technical Identifiers
    IUPAC Name
    [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one
    SMILES
    C1=CC=C2C(=C1)N=CC3=NOC(=O)N23
    InChIKey
    LZMHWZHOZLVYDL-UHFFFAOYSA-N
    InChI
    1S/C9H5N3O2/c13-9-12-7-4-2-1-3-6(7)10-5-8(12)11-14-9/h1-5H
    Synonyms
    [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | EU-0100953 | 3-METHYL(1,1'-BIPHENYL)-4-AMINE | S57V2NMV38 | O0400 | Tocris...
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Frequently Asked Questions

What can I find under Guanylate Cyclase?
This listing collects compounds associated with Guanylate Cyclase within our GPCR/G Protein area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Guanylate Cyclase?
Consider the reported potency of each Guanylate Cyclase compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Guanylate Cyclase compounds?
Each Guanylate Cyclase product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Guanylate Cyclase compounds by activity or structure?
Yes. Filter the Guanylate Cyclase listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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