HSP

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  1. Retaspimycin
    CAS: 857402-23-4 Formula: C31H45N3O8 Molecular Weight: 587.7
    ◐ .Made to order · 8–12 wks Item #: R127859
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    Technical Identifiers
    IUPAC Name
    [(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13,20,22-trihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3-oxo-19-(prop-2-enylamino)-2-azabicyclo[16.3.1]docosa-1(show more
    SMILES
    CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=C(C(=C2O)C1)NCC=C)O)C)OC)OC(=O)N)C)C)O)OC
    InChIKey
    OAKGNIRUXAZDQF-TXHRRWQRSA-N
    InChI
    1S/C31H45N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-11,15-17,show more
    Synonyms
    D09375 | IPI-504 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13,20,22-Trihydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3-oxo-...
  2. Tamoxifen, Agonist of Estrogen receptor-α;Antagonist of Estrogen receptor-α;Agonist of Estrogen receptor-β;Antagonist of Estrogen receptor-β;Agonist of GPER
    CAS: 10540-29-1 EC Number: 234-118-0 Formula: C26H29NO Molecular Weight: 371.51
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: T137975
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    IUPAC Name
    2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
    SMILES
    CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
    InChIKey
    NKANXQFJJICGDU-QPLCGJKRSA-N
    InChI
    1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
    Synonyms
    (Z)-Tamoxifen | ICI 47699 | trans-Tamoxifen
  3. Tamoxifen-ethyl-d5
    CAS: 157698-32-3 Formula: C26H24D5NO Molecular Weight: 376.55
    ◐ .Made to order · 8–12 wks Item #: T334676
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    IUPAC Name
    N,N-dimethyl-2-[4-[(Z)-3,3,4,4,4-pentadeuterio-1,2-diphenylbut-1-enyl]phenoxy]ethanamine
    SMILES
    CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
    InChIKey
    NKANXQFJJICGDU-FUYVPVGLSA-N
    InChI
    1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-/i1D3,4D2
    Synonyms
    J-009441 | (E/Z)-Tamoxifen-d5 | AKOS040739817 | MS-26118 | (Z)-2-(4-(1,2-Diphenyl-1-butenyl-3,3,4,4,4-d5)phenoxy)-N,N...
  4. Rocaglamide(Roc-A)
    CAS: 84573-16-0 PubChem CID: 331783 Formula: C29H31NO7 Molecular Weight: 505.57
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: R276055
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    IUPAC Name
    (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
    SMILES
    CN(C)C(=O)C1C(C2(C(C1O)(C3=C(O2)C=C(C=C3OC)OC)O)C4=CC=C(C=C4)OC)C5=CC=CC=C5
    InChIKey
    DAPAQENNNINUPW-IDAMAFBJSA-N
    InChI
    1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,3show more
    Synonyms
    FRG4N852F7 | B603847K064 | NSC326408 | Rocaglamide | 1H-Cyclopenta(b)benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1...
  5. (R)-(−)-Falcarinol
    CAS: 21852-80-2 PubChem CID: 5281149 Formula: C17H24O Molecular Weight: 244.37
    ◐ .Made to order · 8–12 wks Item #: R337109
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    IUPAC Name
    (3R,9Z)-heptadeca-1,9-dien-4,6-diyn-3-ol
    SMILES
    CCCCCCCC=CCC#CC#CC(C=C)O
    InChIKey
    UGJAEDFOKNAMQD-QXPKXGMISA-N
    InChI
    1S/C17H24O/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17(18)4-2/h4,10-11,17-18H,2-3,5-9,12H2,1H3/b11-10-/t17-/m1/s1
    Synonyms
    FALCARINOL [HSDB] | Q413192 | BDBM50573712 | (R,Z)-Heptadeca-1,9-dien-4,6-diyn-3-ol | MS-23462 | 1,9-Heptadecadiene-4...
  6. Neoantimycin
    CAS: 22862-63-1 Formula: C36H46N2O12 Molecular Weight: 698.76
    ● In Stock — US warehouse, ships to EU* Item #: N329566
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    Technical Identifiers
    IUPAC Name
    N-(15-benzyl-10-butan-2-yl-14-hydroxy-7,13,13-trimethyl-2,5,9,12-tetraoxo-3-propan-2-yl-1,4,8,11-tetraoxacyclopentadec-6-yl)-3-formamido-2-hydroxybenzshow more
    SMILES
    CCC(C)C1C(=O)OC(C(C(=O)OC(C(=O)OC(C(C(C(=O)O1)(C)C)O)CC2=CC=CC=C2)C(C)C)NC(=O)C3=C(C(=CC=C3)NC=O)O)C
    InChIKey
    JIJATTFJYJZEBT-UHFFFAOYSA-N
    InChI
    1S/C36H46N2O12/c1-8-20(4)29-34(45)47-21(5)26(38-31(42)23-15-12-16-24(27(23)40)37-18-39)32(43)49-28(19(2)3)33(44)48-25(17-22-13-10-9-11-14-22)30(41)36(show more
    Synonyms
    1,4,8,11-Tetraoxacyclopentadecane, neoantimycin deriv. | 3-(Formylamino)-2-hydroxy-N-[(3S,6S,7R,10S,14R,15R)-14-hydro...
  7. Palmitic acid-1-(¹³C)
    CAS: 57677-53-9 Formula: (13C)C15H32O2 Molecular Weight: 257.42
    ● In Stock — US warehouse, ships to EU* Item #: P346808
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    IUPAC Name
    (113C)hexadecanoic acid
    SMILES
    CCCCCCCCCCCCCCCC(=O)O
    InChIKey
    IPCSVZSSVZVIGE-LOYIAQTISA-N
    InChI
    1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)/i16+1
    Synonyms
    2QQO35IYD7 | D78975 | HEXADECANOICACID-1-¹³C | Palmitic acid-1-(¹³-C) | DTXSID40432301 | HY-N0830S3 | starbld0016623 ...
  8. Liriodendrin
    CAS: 573-44-4 Formula: C34H46O18 Molecular Weight: 742.72
    ● In Stock — US warehouse, ships to EU* Item #: L171049
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    Technical Identifiers
    IUPAC Name
    2-[4-[6-[3,5-dimethoxy-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2,6-dimethoxyphenoxy]-6show more
    SMILES
    COC1=CC(=CC(=C1OC2C(C(C(C(O2)CO)O)O)O)OC)C3C4COC(C4CO3)C5=CC(=C(C(=C5)OC)OC6C(C(C(C(O6)CO)O)O)O)OC
    InChIKey
    FFDULTAFAQRACT-UHFFFAOYSA-N
    InChI
    1S/C34H46O18/c1-43-17-5-13(6-18(44-2)31(17)51-33-27(41)25(39)23(37)21(9-35)49-33)29-15-11-48-30(16(15)12-47-29)14-7-19(45-3)32(20(8-14)46-4)52-34-28(4show more
    Synonyms
    Eleutheroside E|Liriodendrin|Eleutheroside D|39432-56-9|573-44-4|Acanthoside D|2-[4-[6-[3,5-dimethoxy-4-[3,4,5-trihyd...
  9. TRC 051384
    CAS: 867164-40-7 PubChem CID: 11634093 Formula: C25H31N5O4 Molecular Weight: 465.54
    ● In Stock — US warehouse, ships to EU* Item #: T288893
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    IUPAC Name
    1-(2-morpholin-4-ylethyl)-3-[4-[(E)-3-(6-morpholin-4-ylpyridin-2-yl)prop-2-enoyl]phenyl]urea
    SMILES
    C1COCCN1CCNC(=O)NC2=CC=C(C=C2)C(=O)C=CC3=NC(=CC=C3)N4CCOCC4
    InChIKey
    SQTSPANZQDCPLB-CMDGGOBGSA-N
    InChI
    1S/C25H31N5O4/c31-23(9-8-21-2-1-3-24(27-21)30-14-18-34-19-15-30)20-4-6-22(7-5-20)28-25(32)26-10-11-29-12-16-33-17-13-29/h1-9H,10-19H2,(H2,26,28,32)/b9show more
    Synonyms
    N-[2-(4-Morpholinyl)ethyl]-N'-[4-[3-[6-(4-morpholinyl)-2-pyridinyl]-1-oxo-2-propen-1-yl]phenyl]urea | (Z)-N'-(2-morph...
  10. Geldanamycin from Streptomyces hygroscopicus, Inhibitor of heat shock protein 90 alpha family class B member 1
    CAS: 30562-34-6 EC Number: 805-356-8 Formula: C29H40N2O9 Molecular Weight: 560.64
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: G102383
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    Technical Identifiers
    IUPAC Name
    [(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentshow more
    SMILES
    CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC
    InChIKey
    QTQAWLPCGQOSGP-KSRBKZBZSA-N
    InChI
    1S/C29H40N2O9/c1-15-11-19-25(34)20(14-21(32)27(19)39-7)31-28(35)16(2)9-8-10-22(37-5)26(40-29(30)36)18(4)13-17(3)24(33)23(12-15)38-6/h8-10,13-15,17,22-show more
    Synonyms
    [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16....
  11. Novobiocin Sodium
    CAS: 1476-53-5 EC Number: 216-023-6 PubChem CID: 54730021 Formula: C31H35N2NaO11 Molecular Weight: 634.61
    Solid ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: N129248
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    Technical Identifiers
    IUPAC Name
    sodium;4-[[7-(4-carbamoyloxy-3-hydroxy-5-methoxy-6,6-dimethyloxan-2-yl)oxy-4-hydroxy-8-methyl-2-oxochromen-3-yl]carbamoyl]-2-(3-methylbut-2-enyl)phenoshow more
    SMILES
    CC1=C(C=CC2=C1OC(=O)C(=C2O)NC(=O)C3=CC(=C(C=C3)[O-])CC=C(C)C)OC4C(C(C(C(O4)(C)C)OC)OC(=O)N)O.[Na+]
    InChIKey
    WWPRGAYLRGSOSU-UHFFFAOYSA-M
    InChI
    1S/C31H36N2O11.Na/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44show more
    Synonyms
    EN300-123645 | HMS3656A08 | AS-57689 | Novobiocin (Sodium) | Albamycin;Cathomycin | HMS3374H11 | AKOS037645151 | Alba...
  12. Benzbromarone
    CAS: 3562-84-3 EC Number: 222-630-7 Formula: C17H12Br2O3 Molecular Weight: 424.08
    ● In Stock — US warehouse, ships to EU* Item #: B131634
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    Technical Identifiers
    IUPAC Name
    (3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone
    SMILES
    CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)Br)O)Br
    InChIKey
    WHQCHUCQKNIQEC-UHFFFAOYSA-N
    InChI
    1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
    Synonyms
    MJ 10061 | Prestwick3_000370 | SPBio_002420 | CPD000058310 | NCGC00013895-08 | Prestwick0_000370 | 3,5-Dibromo-4-hydr...
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Frequently Asked Questions

How is the HSP listing put together?
It draws on reported HSP annotations within Metabolic Enzyme/Protease and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a HSP modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the HSP entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for HSP compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For HSP work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the HSP compound I need is not listed?
Search by CAS number or SMILES first, since analogs of HSP compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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