Huntingtin

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  1. 1-{4-[1,2-Diphenyl-2-(p-tolyl)vinyl]phenyl}-1H-pyrrole-2,5-dione
    CAS: 1245606-71-6 Formula: C31H23NO2 Molecular Weight: 441.52
    ◐ .Made to order · 8–12 wks Item #: D486586
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    Technical Identifiers
    IUPAC Name
    1-[4-[(E)-2-(4-methylphenyl)-1,2-diphenylethenyl]phenyl]pyrrole-2,5-dione
    SMILES
    CC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)C3=CC=C(C=C3)N4C(=O)C=CC4=O)C5=CC=CC=C5
    InChIKey
    CIMVFJJQFXGASK-NVQSTNCTSA-N
    InChI
    1S/C31H23NO2/c1-22-12-14-25(15-13-22)30(23-8-4-2-5-9-23)31(24-10-6-3-7-11-24)26-16-18-27(19-17-26)32-28(33)20-21-29(32)34/h2-21H,1H3/b31-30+
    Synonyms
    TPE-Thiol
  2. Buntanetap
    CAS: 116839-68-0 PubChem CID: 11249342 Formula: C20H23N3O2 Molecular Weight: 337.42
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: B647602
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    IUPAC Name
    [(3aS,8bR)-3,4,8b-trimethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-7-yl] N-phenylcarbamate
    SMILES
    CC12CCN(C1N(C3=C2C=C(C=C3)OC(=O)NC4=CC=CC=C4)C)C
    InChIKey
    PBHFNBQPZCRWQP-AZUAARDMSA-N
    InChI
    1S/C20H23N3O2/c1-20-11-12-22(2)18(20)23(3)17-10-9-15(13-16(17)20)25-19(24)21-14-7-5-4-6-8-14/h4-10,13,18H,11-12H2,1-3H3,(H,21,24)/t18-,20+/m0/s1
    Synonyms
    UNII-Z0O4TJ588O | F82032 | ANVS401 | ANVS-401 | buntanetap [INN] | MS-25127 | Phenserine, (+)- | WHO 12342 | R-Phense...
  3. SEN177
    CAS: 2117405-13-5 EC Number: 821-054-9 PubChem CID: 91618245 Formula: C18H19FN6 Molecular Weight: 338.38
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ◐ .Made to order · 8–12 wks Item #: S648491
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    IUPAC Name
    2-fluoro-5-[2-[4-(4-methyl-1,2,4-triazol-3-yl)piperidin-1-yl]pyridin-3-yl]pyridine
    SMILES
    CN1C=NN=C1C2CCN(CC2)C3=C(C=CC=N3)C4=CN=C(C=C4)F
    InChIKey
    AJIAMIPUWJQSPR-UHFFFAOYSA-N
    InChI
    1S/C18H19FN6/c1-24-12-22-23-17(24)13-6-9-25(10-7-13)18-15(3-2-8-20-18)14-4-5-16(19)21-11-14/h2-5,8,11-13H,6-7,9-10H2,1H3
    Synonyms
    2-fluoro-5-[2-[4-(4-methyl-1,2,4-triazol-3-yl)piperidin-1-yl]pyridin-3-yl]pyridine | BDBM50519291 | s77 | SEN177 | 2-...
  4. Benzamide, N-(4-bromophenyl)-3-(((4-bromophenyl)amino)sulfonyl)
    CAS: 300670-16-0 EC Number: 636-913-1 PubChem CID: 1076689 Formula: C19H14Br2N2O3S Molecular Weight: 510.2
    ◐ .Made to order · 8–12 wks Item #: B1066109
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    IUPAC Name
    N-(4-bromophenyl)-3-[(4-bromophenyl)sulfamoyl]benzamide
    SMILES
    C1=CC(=CC(=C1)S(=O)(=O)NC2=CC=C(C=C2)Br)C(=O)NC3=CC=C(C=C3)Br
    InChIKey
    SJJKUNDBFWUAQB-UHFFFAOYSA-N
    InChI
    1S/C19H14Br2N2O3S/c20-14-4-8-16(9-5-14)22-19(24)13-2-1-3-18(12-13)27(25,26)23-17-10-6-15(21)7-11-17/h1-12,23H,(H,22,24)
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the Huntingtin listing put together?
It draws on reported Huntingtin annotations within Neuronal Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Huntingtin modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Huntingtin entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Huntingtin compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Huntingtin work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Huntingtin compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Huntingtin compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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