IGF-1R
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74 products
Popular Products
- GSK1904529ACAS: 1089283-49-7 Formula: C44H47F2N9O5S Molecular Weight: 851.96Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G127237View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)S(=O)(=O)C)OC)NC4=NC=CC(=N4)C5=C(N=C6N5C=CC=C6)C7=CC(=C(C=C7)OC)C(=O)NC8=C(C=CC=C8F)F
- InChIKey
- MOSKATHMXWSZTQ-UHFFFAOYSA-N
- InChI
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- Synonyms
- MOSKATHMXWSZTQ-UHFFFAOYSA-N | SB18897 | Trifluralin [ANSI:BSI:ISO] | AMY24202 | A24618 | GSK 4529 | IGF-1R inhibitor ...
- NBI 31772CAS: 374620-70-9 Formula: C17H11NO7 Molecular Weight: 341.27● In Stock — US warehouse, ships to EU* Item #: N287388View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid
- SMILES
- C1=CC(=C(C=C1C(=O)C2=NC(=CC3=CC(=C(C=C32)O)O)C(=O)O)O)O
- InChIKey
- ZCMFEWUYBFMLIN-UHFFFAOYSA-N
- InChI
- 1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)
- Synonyms
- BDBM50106431 | DTXSID80741040 | UNII-7DYH3XNP6H | 1-[(3,4-Dioxocyclohexa-1,5-dien-1-yl)(hydroxy)methylidene]-6,7-dihy...
- NVP-ADW742CAS: 475488-23-4 Formula: C28H31N5O Molecular Weight: 453.58● In Stock — US warehouse, ships to EU* Item #: N126810View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-(3-phenylmethoxyphenyl)-7-[3-(pyrrolidin-1-ylmethyl)cyclobutyl]pyrrolo[2,3-d]pyrimidin-4-amine
- SMILES
- C1CCN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6
- InChIKey
- LSFLAQVDISHMNB-UHFFFAOYSA-N
- InChI
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- Synonyms
- 5-(3-Benzyloxyphenyl)-7-[trans-3-[(pyrrolidin-1-yl)methyl]cyclobutyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine | AS-56233 |...
- AG-1024, Inhibitor of Insulin-like growth factor I receptorCAS: 65678-07-1 Formula: C14H13BrN2O Molecular Weight: 305.17Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: A126115View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[(3-bromo-5-tert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile
- SMILES
- CC(C)(C)C1=C(C(=CC(=C1)C=C(C#N)C#N)Br)O
- InChIKey
- ABBADGFSRBWENF-UHFFFAOYSA-N
- InChI
- 1S/C14H13BrN2O/c1-14(2,3)11-5-9(4-10(7-16)8-17)6-12(15)13(11)18/h4-6,18H,1-3H3
- Synonyms
- MFCD02179365 | Q27074330 | NCGC00346684-08 | 2-[[3-Bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinit...
- OSI-906 (Linsitinib), Inhibitor of Insulin-like growth factor I receptor;Inhibitor of Insulin receptor;Inhibitor of Insulin receptor-related receptorCAS: 867160-71-2 Formula: C26H23N5O Molecular Weight: 421.51Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: L126224View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
- SMILES
- CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
- InChIKey
- PKCDDUHJAFVJJB-UHFFFAOYSA-N
- InChI
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- Synonyms
- Linsitinib (USAN/INN) | Cis-3-(8-Amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol |...
- NVP-AEW541, Inhibitor of Insulin-like growth factor I receptorCAS: 475489-16-8 Formula: C27H29N5O Molecular Weight: 439.55Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: N125538View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-[3-(azetidin-1-ylmethyl)cyclobutyl]-5-(3-phenylmethoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine
- SMILES
- C1CN(C1)CC2CC(C2)N3C=C(C4=C(N=CN=C43)N)C5=CC(=CC=C5)OCC6=CC=CC=C6
- InChIKey
- AECDBHGVIIRMOI-UHFFFAOYSA-N
- InChI
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- Synonyms
- FT-0744338 | 7-[3-(azetidin-1-ylmethyl)cyclobutyl]-5-(3-phenylmethoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine | AECDBHG...
- BMS-536924, Inhibitor of CYP3A4;Inhibitor of Insulin-like growth factor I receptor;Inhibitor of Insulin receptorCAS: 468740-43-4 Formula: C25H26ClN5O3 Molecular Weight: 479.97Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: B126005View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one
- SMILES
- CC1=CC(=CC2=C1N=C(N2)C3=C(C=CNC3=O)NCC(C4=CC(=CC=C4)Cl)O)N5CCOCC5
- InChIKey
- ZWVZORIKUNOTCS-OAQYLSRUSA-N
- InChI
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- Synonyms
- HY-10262 | N6I | 4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-3-[7-methyl-5-(morpholin-4-yl)-1H-1,3-benzodiazol-...
- Piperonylic Acid● In Stock — Germany Item #: P160472View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1,3-benzodioxole-5-carboxylic acid
- SMILES
- C1OC2=C(O1)C=C(C=C2)C(=O)O
- InChIKey
- VDVJGIYXDVPQLP-UHFFFAOYSA-N
- InChI
- 1S/C8H6O4/c9-8(10)5-1-2-6-7(3-5)12-4-11-6/h1-3H,4H2,(H,9,10)
- Synonyms
- P0459 | KBioSS_001644 | Spectrum3_001022 | 1,3-benzodioxole-5-carbonsäure | Benzo[d][I,3]dioxole-5-carboxylic acid | ...
- LDK378, NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: L127618View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine
- SMILES
- CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl
- InChIKey
- VERWOWGGCGHDQE-UHFFFAOYSA-N
- InChI
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- Synonyms
- K418KG2GET | 5-chloro-2-N-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-4-N-[2-(propane-2-sulfonyl)phenyl]py...
- ChromeceptinCAS: 331859-86-0 Formula: C19H16F3N3O Molecular Weight: 359.35● In Stock — US warehouse, ships to EU* Item #: C338592View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile
- SMILES
- CN(C)C1=CC2=C(C=C1)C(C(=C(O2)N)C#N)C3=CC(=CC=C3)C(F)(F)F
- InChIKey
- GVINXTXGDDSXFQ-UHFFFAOYSA-N
- InChI
- 1S/C19H16F3N3O/c1-25(2)13-6-7-14-16(9-13)26-18(24)15(10-23)17(14)11-4-3-5-12(8-11)19(20,21)22/h3-9,17H,24H2,1-2H3
- Synonyms
- AKOS040758881 | Chromeceptin | NCGC00485180-01 | SCHEMBL4327759 | Chromeceptin, >=98% (HPLC), solid | MS-25660 | 2-am...
- PQ 401, Inhibitor of Insulin-like growth factor I receptorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: P125823View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4-yl)urea
- SMILES
- CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC
- InChIKey
- YBLWOZUPHDKFOT-UHFFFAOYSA-N
- InChI
- 1S/C18H16ClN3O2/c1-11-9-15(13-5-3-4-6-14(13)20-11)21-18(23)22-16-10-12(19)7-8-17(16)24-2/h3-10H,1-2H3,(H2,20,21,22,23)
- Synonyms
- BRD-K67537649-001-01-1 | PQ401 | PQ-401 | BCP28370 | BDBM50230005 | UNII-2N3LV83S8J | HMS2317A04 | 2N3LV83S8J | HMS36...
- Picropodophyllotoxin, Insulin-like growth factor I receptor inhibitorAnalytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P114058View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
- SMILES
- COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O
- InChIKey
- YJGVMLPVUAXIQN-HAEOHBJNSA-N
- InChI
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- Synonyms
- Picropodophyllotoxin;Picropodophyllin;PPP | KBioGR_002538 | 0F35AOI227 | 1352873-82-5 | DTXSID9025740 | Kyselina isof...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the IGF-1R listing put together?
It draws on reported IGF-1R annotations within Protein Tyrosine Kinase/RTK and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an IGF-1R modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the IGF-1R entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for IGF-1R compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For IGF-1R work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the IGF-1R compound I need is not listed?
Search by CAS number or SMILES first, since analogs of IGF-1R compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.