Indoleamine 2,3-Dioxygenase (IDO)

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  1. IDO-IN-1
    CAS: 914638-30-5 PubChem CID: 135741412 Formula: C9H7BrFN5O2 Molecular Weight: 316.087
    ● In Stock — US warehouse, ships to EU* Item #: Z178183
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    IUPAC Name
    4-amino-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
    SMILES
    C1=CC(=C(C=C1N=C(C2=NON=C2N)NO)Br)F
    InChIKey
    ORHZJUSHZUCMKR-UHFFFAOYSA-N
    InChI
    1S/C9H7BrFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14)
    Synonyms
    (Z)-4-amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
  2. β-Cembrenediol
    CAS: 57605-81-9 Formula: C20H34O2 Molecular Weight: 306.48
    ◐ .Made to order · 8–12 wks Item #: C275839
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    IUPAC Name
    (1R,3R,4Z,8Z,12S,13Z)-1,5,9-trimethyl-12-propan-2-ylcyclotetradeca-4,8,13-triene-1,3-diol
    SMILES
    CC1=CCCC(=CC(CC(C=CC(CC1)C(C)C)(C)O)O)C
    InChIKey
    RIVKDDXPCFBMOV-PCFHHCMKSA-N
    InChI
    1S/C20H34O2/c1-15(2)18-10-9-16(3)7-6-8-17(4)13-19(21)14-20(5,22)12-11-18/h7,11-13,15,18-19,21-22H,6,8-10,14H2,1-5H3/b12-11-,16-7-,17-13-/t18-,19+,20+/show more
    Synonyms
    (1R,3R,4Z,8Z,12S,13Z)-1,5,9-trimethyl-12-propan-2-ylcyclotetradeca-4,8,13-triene-1,3-diol | beta -Cembrenediol | (1R-...
  3. Necrostatin-1, Inhibitor of indoleamine 2;3-dioxygenase 1;Inhibitor of receptor interacting serine/threonine kinase 1
    CAS: 4311-88-0 Formula: C13H13N3OS Molecular Weight: 259.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: N125522
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    IUPAC Name
    5-(1H-indol-3-ylmethyl)-3-methyl-2-sulfanylideneimidazolidin-4-one
    SMILES
    CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
    InChIKey
    TXUWMXQFNYDOEZ-UHFFFAOYSA-N
    InChI
    1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18)
    Synonyms
    5-(1H-indol-3-ylmethyl)-3-methyl-2-sulfanyl-3,5-dihydro-4H-imidazol-4-one | 5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxo...
  4. PF-06840003, Inhibitor of indoleamine 2;3-dioxygenase 1
    CAS: 198474-05-4 PubChem CID: 23063810 Formula: C12H9FN2O2 Molecular Weight: 232.21
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P175464
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    IUPAC Name
    3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
    SMILES
    C1C(C(=O)NC1=O)C2=CNC3=C2C=C(C=C3)F
    InChIKey
    MXKLDYKORJEOPR-UHFFFAOYSA-N
    InChI
    1S/C12H9FN2O2/c13-6-1-2-10-7(3-6)9(5-14-10)8-4-11(16)15-12(8)17/h1-3,5,8,14H,4H2,(H,15,16,17)
    Synonyms
    AKOS027252536 | EOS200271 | EOS-200271 | Q420698 | US9603836, Compound 1 | GTPL9565 | A925049 | s8657 | SCHEMBL546346...
  5. Palmatine
    CAS: 3486-67-7 Formula: C21H22NO4+ Molecular Weight: 352.4
    ● In Stock — US warehouse, ships to EU* Item #: P111384
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    IUPAC Name
    2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
    SMILES
    COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC
    InChIKey
    QUCQEUCGKKTEBI-UHFFFAOYSA-N
    InChI
    1S/C21H22NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,9-12H,7-8H2,1-4H3/q+1
    Synonyms
    KBio2_007496 | PALMITINE | 7,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxyberbinium | KBio1_001659 | KBio3_001854 | Palma...
  6. Palmatine
    CAS: 3486-67-7 Formula: C21H22NO4+ Molecular Weight: 352.4
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: P111383
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    IUPAC Name
    2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
    SMILES
    COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC
    InChIKey
    QUCQEUCGKKTEBI-UHFFFAOYSA-N
    InChI
    1S/C21H22NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,9-12H,7-8H2,1-4H3/q+1
    Synonyms
    KBio2_007496 | PALMITINE | 7,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxyberbinium | KBio1_001659 | KBio3_001854 | Palma...
  7. INCB024360 analogue
    CAS: 914471-09-3 Formula: C9H7ClFN5O2 Molecular Weight: 271.64
    ● In Stock — US warehouse, ships to EU* Item #: I126281
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    IUPAC Name
    4-amino-N'-(3-chloro-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide
    SMILES
    C1=CC(=C(C=C1N=C(C2=NON=C2N)NO)Cl)F
    InChIKey
    HGXSLPIXNPASGZ-UHFFFAOYSA-N
    InChI
    1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14)
    Synonyms
    NSC785571 | NSC-785571 | SCHEMBL19654569 | UNII-2HR315841W | 914471-09-3 (INCB14943) | BDBM50300305 | (4E)-4-[(3-chlo...
  8. NLG919, Inhibitor of indoleamine 2;3-dioxygenase 1;Inhibitor of tryptophan 2;3-dioxygenase
    CAS: 1402836-58-1 Formula: C18H22N2O Molecular Weight: 282.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: N129887
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    IUPAC Name
    1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol
    SMILES
    C1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O
    InChIKey
    YTRRAUACYORZLX-UHFFFAOYSA-N
    InChI
    1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2
    Synonyms
    HY-13983 | BDBM50126144 | GTPL9019 | NLG919 (GDC-0919) | YTRRAUACYORZLX-UHFFFAOYSA-N | 2-Naphthalenesulfonic acid, 7,...
  9. 4-[(1-Naphtho[2,3-d]triazol-1-yl)methyl]benzoic acid
    CAS: 202582-08-9 Formula: C18H13N3O2 Molecular Weight: 303.31
    ◐ .Made to order · 8–12 wks Item #: N346524
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    IUPAC Name
    4-(benzo[f]benzotriazol-3-ylmethyl)benzoic acid
    SMILES
    C1=CC=C2C=C3C(=CC2=C1)N=NN3CC4=CC=C(C=C4)C(=O)O
    InChIKey
    CPVINIGXGKJNOS-UHFFFAOYSA-N
    InChI
    1S/C18H13N3O2/c22-18(23)13-7-5-12(6-8-13)11-21-17-10-15-4-2-1-3-14(15)9-16(17)19-20-21/h1-10H,11H2,(H,22,23)
    Synonyms
    AKOS040758952 | HY-D0033 | DTXSID60357360 | 4-((1H-Naphtho[2,3-d][1,2,3]triazol-1-yl)methyl)benzoic acid | J-100024 |...
  10. Palmatine chloride
    CAS: 10605-02-4 EC Number: 830-625-1 PubChem CID: 73442 Formula: C21H22ClNO4 Molecular Weight: 387.86
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P274975
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    IUPAC Name
    2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium;chloride
    SMILES
    COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC.[Cl-]
    InChIKey
    RLQYRXCUPVKSAW-UHFFFAOYSA-M
    InChI
    1S/C21H22NO4.ClH/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4;/h5-6,9-12H,7-8H2,1-4H3;1H/q+1;/p-1
    Synonyms
    MLS002153886 | P2138 | UNII-ZJ6W8881Z8 | Palmatine Hydrochloride,(S) | ZJ6W8881Z8 | 2,3-DNT | 2-Bromo-2-methylpropano...
  11. 2-Hydrazinobenzothiazole
    CAS: 615-21-4 Formula: C7H7N3S Molecular Weight: 165.21
    ● In Stock — US warehouse, ships to EU* Item #: H137644
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    IUPAC Name
    1,3-benzothiazol-2-ylhydrazine
    SMILES
    C1=CC=C2C(=C1)N=C(S2)NN
    InChIKey
    JYSUYJCLUODSLN-UHFFFAOYSA-N
    InChI
    1S/C7H7N3S/c8-10-7-9-5-3-1-2-4-6(5)11-7/h1-4H,8H2,(H,9,10)
    Synonyms
    WLN: T56 BN DSJ CMZ | STK394984 | Benzothiazol-2-yl-hydrazine | IDO1IN1 | IDO1-IN-1 | USAF EK-3967 | (2-BENZOTHIAZOLY...
  12. 1-Methyl-D-tryptophan, mTORC1 activator
    CAS: 110117-83-4 Formula: C12H14N2O2 Molecular Weight: 218.25
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ● In Stock — US warehouse, ships to EU* Item #: M115830
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    IUPAC Name
    (2R)-2-amino-3-(1-methylindol-3-yl)propanoic acid
    SMILES
    CN1C=C(C2=CC=CC=C21)CC(C(=O)O)N
    InChIKey
    ZADWXFSZEAPBJS-SNVBAGLBSA-N
    InChI
    1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1
    Synonyms
    AKOS015850753 | Indoximod (NLG-8189) | AKOS015898463 | D-1-methyltryptophan | NCGC00346842-01 | NSC721782 | NSC-72178...
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Frequently Asked Questions

How is the Indoleamine 2,3-Dioxygenase (IDO) listing put together?
It draws on reported Indoleamine 2,3-Dioxygenase (IDO) annotations within Metabolic Enzyme/Protease and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an Indoleamine 2,3-Dioxygenase (IDO) modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Indoleamine 2,3-Dioxygenase (IDO) entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Indoleamine 2,3-Dioxygenase (IDO) compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Indoleamine 2,3-Dioxygenase (IDO) work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Indoleamine 2,3-Dioxygenase (IDO) compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Indoleamine 2,3-Dioxygenase (IDO) compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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