JAK
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447 products
Popular Products
- Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitorCAS: 111358-88-4 Formula: C26H21N3O4 Molecular Weight: 439.46Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: L275009View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
- InChIKey
- UIARLYUEJFELEN-LROUJFHJSA-N
- InChI
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- Synonyms
- SPM-924 | (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanod...
- ZM 449829Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: Z275707View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-naphthalen-2-ylprop-2-en-1-one
- SMILES
- C=CC(=O)C1=CC2=CC=CC=C2C=C1
- InChIKey
- FOTCGZPFSUWZBN-UHFFFAOYSA-N
- InChI
- 1S/C13H10O/c1-2-13(14)12-8-7-10-5-3-4-6-11(10)9-12/h2-9H,1H2
- Synonyms
- 1-(2-Naphthalenyl)-2-propen-1-one
- ZM 39923 HClCAS: 1021868-92-7 Formula: C23H25NO.HCl Molecular Weight: 367.91Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: Z129618View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one;hydrochloride
- SMILES
- CC(C)N(CCC(=O)C1=CC2=CC=CC=C2C=C1)CC3=CC=CC=C3.Cl
- InChIKey
- NJTUORMLOPXPBY-UHFFFAOYSA-N
- InChI
- 1S/C23H25NO.ClH/c1-18(2)24(17-19-8-4-3-5-9-19)15-14-23(25)22-13-12-20-10-6-7-11-21(20)16-22;/h3-13,16,18H,14-15,17H2,1-2H3;1H
- Synonyms
- DTXSID301017077 | 3-BENZYLISOPROPYLAMINO-1-NAPHTHALEN-2-YL-PROPAN-1-ONE HYDROCHLORIDE | ZM39923 HCl;ZM-39923 HCl | 3-...
- CurculigosideCAS: 85643-19-2 Formula: C22H26O11 Molecular Weight: 466.44Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.● In Stock — US warehouse, ships to EU* Item #: C399228View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [5-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl 2,6-dimethoxybenzoate
- SMILES
- COC1=C(C(=CC=C1)OC)C(=O)OCC2=C(C=CC(=C2)O)OC3C(C(C(C(O3)CO)O)O)O
- InChIKey
- SJJRKHVKAXVFJQ-QKYBYQKWSA-N
- InChI
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- Synonyms
- [5-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl2,6-dimethoxybenzoate | A6...
- SwertiamarineSolid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: S110090View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3S,4R,4aR)-4-ethenyl-4a-hydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4,5,6-tetrahydropyrano[3,4-c]pyran-8-one
- SMILES
- C=CC1C(OC=C2C1(CCOC2=O)O)OC3C(C(C(C(O3)CO)O)O)O
- InChIKey
- HEYZWPRKKUGDCR-QBXMEVCASA-N
- InChI
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- Synonyms
- A811580 | Swertiamarin, >=95% (LC/MS-ELSD) | 1H,3H-Pyrano(3,4-c)pyran-1-one, 5-ethenyl-6-(beta-D-glucopyranosyloxy)-4...
- Atractylenolide ICAS: 73069-13-3 Formula: C15H18O2 Molecular Weight: 230.3Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.● In Stock — US warehouse, ships to EU* Item #: A304497View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (4aS,8aS)-3,8a-dimethyl-5-methylidene-4a,6,7,8-tetrahydro-4H-benzo[f][1]benzofuran-2-one
- SMILES
- CC1=C2CC3C(=C)CCCC3(C=C2OC1=O)C
- InChIKey
- ZTVSGQPHMUYCRS-SWLSCSKDSA-N
- InChI
- 1S/C15H18O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h8,12H,1,4-7H2,2-3H3/t12-,15+/m0/s1
- Synonyms
- HMS3886N08 | Atractylenolide I | Atractylenolide I, >=98% (HPLC) | s8291 | (4aS,8aS)-3,8a-dimethyl-5-methylene-4a,5,6...
- Ruxolitinib phosphate salt, Tyrosine-protein kinase JAK2 inhibitorCAS: 1092939-17-7 EC Number: 641-390-8 PubChem CID: 25127112 Formula: C17H21N6O4P Molecular Weight: 404.4● In Stock — US warehouse, ships to EU* Item #: R171967View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;phosphoric acid
- SMILES
- C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
- InChIKey
- JFMWPOCYMYGEDM-XFULWGLBSA-N
- InChI
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- Synonyms
- (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrilephosphate | Jakavi (TN) | (3R)...
- LFM-A13● In Stock — US warehouse, ships to EU* Item #: L286934View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide
- SMILES
- CC(=C(C#N)C(=O)NC1=C(C=CC(=C1)Br)Br)O
- InChIKey
- UVSVTDVJQAJIFG-UHFFFAOYSA-N
- InChI
- 1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)
- Synonyms
- AKOS028108222 | alpha-Cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide | KBio3_001038 | HMS3370M16 | L...
- LY2784544, Tyrosine-protein kinase JAK2 inhibitorCAS: 1229236-86-5 Formula: C23H25ClFN7O Molecular Weight: 469.95Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: L126490View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine
- SMILES
- CC1=CC(=NN1)NC2=NN3C(=C(N=C3C(=C2)CN4CCOCC4)C)CC5=C(C=C(C=C5)Cl)F
- InChIKey
- SQSZANZGUXWJEA-UHFFFAOYSA-N
- InChI
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- Synonyms
- C23H25ClFN7O | 3-(4-chloro-2-fluorobenzyl)-2-methyl-N-(3-methyl-1H-pyrazol-5-yl)-8-(morpholinomethyl)imidazo[1,2-b]py...
- WHI-P131 hydrochloride◐ .Made to order · 8–12 wks Item #: W274689View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol;hydrochloride
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC.Cl
- InChIKey
- HNJNNCPPISFBGR-UHFFFAOYSA-N
- InChI
- 1S/C16H15N3O3.ClH/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-3-5-11(20)6-4-10;/h3-9,20H,1-2H3,(H,17,18,19);1H
- Synonyms
- 4-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenolhydrochloride
- WHI-P154, Inhibitor of epidermal growth factor receptor;Inhibitor of Janus kinase 1;Inhibitor of Janus kinase 2;Inhibitor of Janus kinase 3CAS: 211555-04-3 EC Number: 809-014-9 PubChem CID: 3795 Formula: C16H14BrN3O3 Molecular Weight: 376.2Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: W125072View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-bromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC
- InChIKey
- CBIAKDAYHRWZCU-UHFFFAOYSA-N
- InChI
- 1S/C16H14BrN3O3/c1-22-14-6-10-12(7-15(14)23-2)18-8-19-16(10)20-9-3-4-13(21)11(17)5-9/h3-8,21H,1-2H3,(H,18,19,20)
- Synonyms
- HB1431 | BCP09619 | SR-02000000171 | 4-(3'-bromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline | GTPL5993 | 2-Bromo...
- WHI-P97Solid ≥98%● In Stock — US warehouse, ships to EU* Item #: W125855View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2,6-dibromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C(=C3)Br)O)Br)OC
- InChIKey
- YVCXQRVVNQMZEI-UHFFFAOYSA-N
- InChI
- 1S/C16H13Br2N3O3/c1-23-13-5-9-12(6-14(13)24-2)19-7-20-16(9)21-8-3-10(17)15(22)11(18)4-8/h3-7,22H,1-2H3,(H,19,20,21)
- Synonyms
- HMS3265F24 | 2,6-Dibromo-4-((6,7-dimethoxyquinazolin-4-yl)amino)phenol | 2,6-Dibromo-4-(6,7-dimethoxy-quinazolin-4-yl...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
Which compounds are listed for JAK?
Compounds associated with JAK are grouped here under the Protein Tyrosine Kinase/RTK classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does JAK sit within Protein Tyrosine Kinase/RTK?
JAK is one target listing within the Protein Tyrosine Kinase/RTK classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from JAK?
For compounds listed under JAK, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for JAK?
Browse the parent Protein Tyrosine Kinase/RTK listing to reach targets neighbouring JAK, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.












