Kallikrein

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  1. PKSI-527
    CAS: 128837-71-8 PubChem CID: 3035562 Formula: C25H32ClN3O4 Molecular Weight: 474
    ◐ .Made to order · 8–12 wks Item #: P275072
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    Technical Identifiers
    IUPAC Name
    2-[4-[[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]acetic acid;hydrochloride
    SMILES
    C1CC(CCC1CN)C(=O)NC(CC2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)CC(=O)O.Cl
    InChIKey
    NAXNMKUKSBHHMP-QCXPCDNBSA-N
    InChI
    1S/C25H31N3O4.ClH/c26-16-19-6-10-20(11-7-19)24(31)28-22(14-17-4-2-1-3-5-17)25(32)27-21-12-8-18(9-13-21)15-23(29)30;/h1-5,8-9,12-13,19-20,22H,6-7,10-11show more
    Synonyms
    DTXSID00926216 | Benzeneacetic acid, 4-((2-(((4-(aminomethyl)cyclohexyl)carbonyl)amino)-1-oxo-3-phenylpropyl)amino)-,...
  2. LSP-249
    CAS: 1801253-04-2 Formula: C24H22ClN5O Molecular Weight: 431.92
    ● In Stock — US warehouse, ships to EU* Item #: L413428
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    IUPAC Name
    N-[(6-amino-2,4-dimethylpyridin-3-yl)methyl]-2-[(3-chloroquinolin-6-yl)methyl]pyridine-4-carboxamide
    SMILES
    CC1=CC(=NC(=C1CNC(=O)C2=CC(=NC=C2)CC3=CC4=CC(=CN=C4C=C3)Cl)C)N
    InChIKey
    BDLURRLRBKLEDL-UHFFFAOYSA-N
    InChI
    1S/C24H22ClN5O/c1-14-7-23(26)30-15(2)21(14)13-29-24(31)17-5-6-27-20(11-17)9-16-3-4-22-18(8-16)10-19(25)12-28-22/h3-8,10-12H,9,13H2,1-2H3,(H2,26,30)(H,show more
  3. avoralstat, Plasma kallikrein inhibitor
    CAS: 918407-35-9 EC Number: 811-719-1 PubChem CID: 86566678 Formula: C28H27N5O5 Molecular Weight: 513.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: A607821
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    IUPAC Name
    3-[2-[(4-carbamimidoylphenyl)carbamoyl]-4-ethenyl-5-methoxyphenyl]-6-(cyclopropylmethylcarbamoyl)pyridine-2-carboxylic acid
    SMILES
    COC1=CC(=C(C=C1C=C)C(=O)NC2=CC=C(C=C2)C(=N)N)C3=C(N=C(C=C3)C(=O)NCC4CC4)C(=O)O
    InChIKey
    TUWMKPVJGGWGNL-UHFFFAOYSA-N
    InChI
    1S/C28H27N5O5/c1-3-16-12-21(26(34)32-18-8-6-17(7-9-18)25(29)30)20(13-23(16)38-2)19-10-11-22(33-24(19)28(36)37)27(35)31-14-15-4-5-15/h3,6-13,15H,1,4-5,show more
    Synonyms
    3-(2-((4-carbamimidoylphenyl)carbamoyl)-5-methoxy-4-vinylphenyl)-6-((cyclopropylmethyl)carbamoyl)picolinic acid | BCX...
  4. ecallantide, INHIBITOR of Plasma kallikrein inhibitor
    CAS: 460738-38-9 PubChem CID: 44152182
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .US Made to order · 2–4 wks Item #: rp173941
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    SMILES
    CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4CCC[C@H]4C(=O)N[C@H](C(=O)N[C@Hshow more
    InChIKey
    VBGWSQKGUZHFPS-VGMMZINCSA-N
    Synonyms
    DX-88 | Kalbitor | GTPL6955 | FOV2302 | Ecallantide
  5. berotralstat, Inhibitor of kallikrein B1
    CAS: 1809010-50-1 PubChem CID: 137528262
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: B608004
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    IUPAC Name
    2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
    SMILES
    C1CC1CNC(C2=CC(=C(C=C2)F)NC(=O)C3=CC(=NN3C4=CC=CC(=C4)CN)C(F)(F)F)C5=CC=CC(=C5)C#N
    InChIKey
    UXNXMBYCBRBRFD-MUUNZHRXSA-N
    InChI
    1S/C30H26F4N6O/c31-24-10-9-22(28(37-17-18-7-8-18)21-5-1-3-19(11-21)15-35)13-25(24)38-29(41)26-14-27(30(32,33)34)39-40(26)23-6-2-4-20(12-23)16-36/h1-6,show more
    Synonyms
    EU-0100725 | EX-A5537 | HY-109127 | Tin, rod, 500mm, diameter 9.5mm, 99.75% | BDBM50602174 | Q413540 | Orladeyo | 1-[...
  6. PPACK II diTFA
    CAS: 649748-23-2 PubChem CID: 131698209 Formula: C29H35ClF6N6O7 Molecular Weight: 615.04
    ◐ .Made to order · 8–12 wks Item #: P648671
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    IUPAC Name
    (2R)-2-amino-N-[(2S)-1-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide;2,2,2-trifluoshow more
    SMILES
    C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CCCN=C(N)N)C(=O)CCl)N.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O
    InChIKey
    JVMDQRDDGVKUMG-WOSURGFKSA-N
    InChI
    1S/C25H33ClN6O3.2C2HF3O2/c26-16-22(33)20(12-7-13-30-25(28)29)31-24(35)21(15-18-10-5-2-6-11-18)32-23(34)19(27)14-17-8-3-1-4-9-17;2*3-2(4,5)1(6)7/h1-6,8show more
  7. Berotralstat dihydrochloride, Plasma kallikrein inhibitor
    CAS: 1809010-52-3 PubChem CID: 139030242 Formula: C30H28Cl2F4N6O Molecular Weight: 635.48
    ◐ .Made to order · 8–12 wks Item #: B650745
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    Pricing & Pack Sizes
    Technical Identifiers
    SMILES
    C1CC1CN[C@@H](C2=CC(=C(C=C2)F)NC(=O)C3=CC(=NN3C4=CC=CC(=C4)CN)C(F)(F)F)C5=CC=CC(=C5)C#N.Cl.Cl
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

Which compounds are listed for Kallikrein?
Compounds associated with Kallikrein are grouped here under the Immunology/Inflammation classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Kallikrein sit within Immunology/Inflammation?
Kallikrein is one target listing within the Immunology/Inflammation classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Kallikrein?
For compounds listed under Kallikrein, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Kallikrein?
Browse the parent Immunology/Inflammation listing to reach targets neighbouring Kallikrein, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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