Legumain

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  1. RR-11a analog
    CAS: 685543-66-2 PubChem CID: 11294791 Formula: C22H29N5O8 Molecular Weight: 491.49
    ◐ .Made to order · 8–12 wks Item #: R647865
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    Technical Identifiers
    IUPAC Name
    ethyl (E)-4-[(2-amino-2-oxoethyl)-[[(2S)-2-[[(2S)-2-(phenylmethoxycarbonylamino)propanoyl]amino]propanoyl]amino]amino]-4-oxobut-2-enoate
    SMILES
    CCOC(=O)C=CC(=O)N(CC(=O)N)NC(=O)C(C)NC(=O)C(C)NC(=O)OCC1=CC=CC=C1
    InChIKey
    YGVKPQSVBJEMMQ-BWLFODOESA-N
    InChI
    1S/C22H29N5O8/c1-4-34-19(30)11-10-18(29)27(12-17(23)28)26-21(32)15(3)24-20(31)14(2)25-22(33)35-13-16-8-6-5-7-9-16/h5-11,14-15H,4,12-13H2,1-3H3,(H2,23,show more
  2. Legumain inhibitor 1
    CAS: 2361157-34-6 Formula: C23H25N5O4S Molecular Weight: 467.54
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: L1495901
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the Legumain listing put together?
It draws on reported Legumain annotations within Neuronal Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Legumain modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Legumain entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Legumain compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Legumain work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Legumain compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Legumain compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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