mAChR

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  1. PD 102807, Antagonist of M 4 receptor
    CAS: 23062-91-1 PubChem CID: 4995951 Formula: C23H24N2O4 Molecular Weight: 392.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P288145
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    IUPAC Name
    ethyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
    SMILES
    CCOC(=O)C1=C(NC2=C1C3=C(C=C2)OC4C5=C(CCN4C3)C=C(C=C5)OC)C
    InChIKey
    VDDUJINYXKGZLV-UHFFFAOYSA-N
    InChI
    1S/C23H24N2O4/c1-4-28-23(26)20-13(2)24-18-7-8-19-17(21(18)20)12-25-10-9-14-11-15(27-3)5-6-16(14)22(25)29-19/h5-8,11,22,24H,4,9-10,12H2,1-3H3
    Synonyms
    3,6a,11,14-tetrahydro-9-methoxy-2-methyl-12h-isoquino[1,2-b]pyrrolo[3,2-f][1,3]benzoxazine-1-carboxylic acid ethyl es...
  2. N-desmethylclozapine, Allosteric modulator of M 1 receptor
    CAS: 6104-71-8 EC Number: 636-421-7 Formula: C17H17ClN4 Molecular Weight: 312.8
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: N298816
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    IUPAC Name
    3-chloro-6-piperazin-1-yl-11H-benzo[b][1,4]benzodiazepine
    SMILES
    C1CN(CCN1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42
    InChIKey
    JNNOSTQEZICQQP-UHFFFAOYSA-N
    InChI
    1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19-20H,7-10H2
    Synonyms
    BCP30683 | CAS_2820 | GTPL333 | UNII-1I9001LWY8 | BDBM50122054 | BRD-K10042277-001-04-3 | Desmethylclozapine | 3-chlo...
  3. Piperidolate
    CAS: 82-98-4 PubChem CID: 4839 Formula: C21H25NO2 Molecular Weight: 323.43
    ● In Stock — US warehouse, ships to EU* Item #: P195207
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    IUPAC Name
    (1-ethylpiperidin-3-yl) 2,2-diphenylacetate
    SMILES
    CCN1CCCC(C1)OC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3
    InChIKey
    KTHVBAZBLKXIHZ-UHFFFAOYSA-N
    InChI
    1S/C21H25NO2/c1-2-22-15-9-14-19(16-22)24-21(23)20(17-10-5-3-6-11-17)18-12-7-4-8-13-18/h3-8,10-13,19-20H,2,9,14-16H2,1H3
    Synonyms
    3-Piperidinol, 1-ethyl-, diphenylacetate | KBio3_002408 | Spectrum_001383 | HY-B0962A | MS-24807 | SPBio_001086 | KBi...
  4. Gallamine Triethiodide, Muscle-type nicotinic acetylcholine receptor antagonist
    CAS: 65-29-2 EC Number: 200-605-1 PubChem CID: 6172 Formula: C30H60I3N3O3 Molecular Weight: 891.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: G129967
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    IUPAC Name
    2-[2,3-bis[2-(triethylazaniumyl)ethoxy]phenoxy]ethyl-triethylazanium;triiodide
    SMILES
    CC[N+](CC)(CC)CCOC1=C(C(=CC=C1)OCC[N+](CC)(CC)CC)OCC[N+](CC)(CC)CC.[I-].[I-].[I-]
    InChIKey
    REEUVFCVXKWOFE-UHFFFAOYSA-K
    InChI
    1S/C30H60N3O3.3HI/c1-10-31(11-2,12-3)22-25-34-28-20-19-21-29(35-26-23-32(13-4,14-5)15-6)30(28)36-27-24-33(16-7,17-8)18-9;;;/h19-21H,10-18,22-27H2,1-9Hshow more
    Synonyms
    1,2,3-Tri(beta-diethylaminoethoxy)benzene triethiodide | GALLAMINE TRIETHIODIDE [MI] | 3.697 R.P. | Gallamine triiodo...
  5. AF-DX 384, Antagonist of M 1 receptor;Antagonist of M 2 receptor;Antagonist of M 3 receptor;Antagonist of M 4 receptor;Antagonist of M 5 receptor
    CAS: 118290-27-0 Formula: C27H38N6O2 Molecular Weight: 478.64
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: A274921
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    IUPAC Name
    N-[2-[2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
    SMILES
    CCCN(CCC)CC1CCCCN1CCNC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4
    InChIKey
    MZDYABXXPZNUCT-UHFFFAOYSA-N
    InChI
    1S/C27H38N6O2/c1-3-16-31(17-4-2)20-21-10-7-8-18-32(21)19-15-29-27(35)33-24-13-6-5-11-22(24)26(34)30-23-12-9-14-28-25(23)33/h5-6,9,11-14,21H,3-4,7-8,10show more
    Synonyms
    N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carbox...
  6. SM21 maleate
    CAS: 155059-42-0 Formula: C18H24ClNO3.C4H4O4 Molecular Weight: 453.92
    ◐ .Made to order · 8–12 wks Item #: S276279
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    IUPAC Name
    (Z)-but-2-enedioic acid;(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-(4-chlorophenoxy)butanoate
    SMILES
    CCC(C(=O)OC1CC2CCC(C1)N2C)OC3=CC=C(C=C3)Cl.C(=CC(=O)O)C(=O)O
    InChIKey
    BHXGTFUQDGMXHA-BTJKTKAUSA-N
    InChI
    1S/C18H24ClNO3.C4H4O4/c1-3-17(22-15-8-4-12(19)5-9-15)18(21)23-16-10-13-6-7-14(11-16)20(13)2;5-3(6)1-2-4(7)8/h4-5,8-9,13-14,16-17H,3,6-7,10-11H2,1-2H3;show more
    Synonyms
    J-009168 | (Z)-but-2-enedioic acid;(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 2-(4-chlorophenoxy)butanoate | Butanoic a...
  7. Olanzapine, D2-like dopamine receptor antagonist
    CAS: 132539-06-1 EC Number: 603-618-4 Formula: C17H20N4S Molecular Weight: 312.43
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: O126519
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    IUPAC Name
    2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
    SMILES
    CC1=CC2=C(S1)NC3=CC=CC=C3N=C2N4CCN(CC4)C
    InChIKey
    KVWDHTXUZHCGIO-UHFFFAOYSA-N
    InChI
    1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3
    Synonyms
    NSC_4585 | Olanzapine Teva | 2-Methyl-4-(4-methylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine | OLANZAPIN...
  8. 5-hydroxymethyl Tolterodine (PNU 200577, 5-HMT, 5-HM)
    CAS: 207679-81-0 Formula: C22H31NO2 Molecular Weight: 341.49
    ● In Stock — US warehouse, ships to EU* Item #: H129983
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    IUPAC Name
    2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenol
    SMILES
    CC(C)N(CCC(C1=CC=CC=C1)C2=C(C=CC(=C2)CO)O)C(C)C
    InChIKey
    DUXZAXCGJSBGDW-HXUWFJFHSA-N
    InChI
    1S/C22H31NO2/c1-16(2)23(17(3)4)13-12-20(19-8-6-5-7-9-19)21-14-18(15-24)10-11-22(21)25/h5-11,14,16-17,20,24-25H,12-13,15H2,1-4H3/t20-/m1/s1
    Synonyms
    Desfesoterodine | NCGC00346585-01 | (R)-2-(3-(Diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol | AMY14591 | ...
  9. Milameline hydrochloride
    CAS: 139886-04-7 Formula: C8H14N2O.HCl Molecular Weight: 190.67
    ◐ .Made to order · 8–12 wks Item #: M288672
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    IUPAC Name
    (E)-N-methoxy-1-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)methanimine;hydrochloride
    SMILES
    CN1CCC=C(C1)C=NOC.Cl
    InChIKey
    WEBMRZODPLSRKR-MLBSPLJJSA-N
    InChI
    1S/C8H14N2O.ClH/c1-10-5-3-4-8(7-10)6-9-11-2;/h4,6H,3,5,7H2,1-2H3;1H/b9-6+;
    Synonyms
    RU 35926 | 1,2,5,6-Tetrahydro-1-methylnicotinaldehyde (E)-O-methyloxime monohydrochloride | MILAMELINE HYDROCHLORIDE ...
  10. Atropine, Muscarinic acetylcholine receptor M2 antagonist
    CAS: 51-55-8 EC Number: 200-104-8 Formula: C17H23NO3 Molecular Weight: 289.37
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: A135946
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    IUPAC Name
    [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate
    SMILES
    CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3
    InChIKey
    RKUNBYITZUJHSG-PJPHBNEVSA-N
    InChI
    1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15?,16?
    Synonyms
    (1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate | alpha-(Hydroxymethyl)benzeneacetic a...
  11. BML-278
    CAS: 15301-69-6 Formula: C24H25NO4 Molecular Weight: 391.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: B348267
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    IUPAC Name
    2-piperidin-1-ylethyl 3-methyl-4-oxo-2-phenylchromene-8-carboxylate
    SMILES
    CC1=C(OC2=C(C1=O)C=CC=C2C(=O)OCCN3CCCCC3)C4=CC=CC=C4
    InChIKey
    SPIUTQOUKAMGCX-UHFFFAOYSA-N
    InChI
    1S/C24H25NO4/c1-17-21(26)19-11-8-12-20(23(19)29-22(17)18-9-4-2-5-10-18)24(27)28-16-15-25-13-6-3-7-14-25/h2,4-5,8-12H,3,6-7,13-16H2,1H3
    Synonyms
    2-(1-Piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate # | SCHEMBL25801 | beta-piperidinoethyl 3-me...
  12. Oxyphenonium bromide, Muscarinic acetylcholine receptor M1 antagonist
    CAS: 50-10-2 EC Number: 200-010-7 Formula: C₂₁H₃₄NO₃Br Molecular Weight: 428.40
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: O332704
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    IUPAC Name
    2-(2-cyclohexyl-2-hydroxy-2-phenylacetyl)oxyethyl-diethyl-methylazanium;bromide
    SMILES
    CC[N+](C)(CC)CCOC(=O)C(C1CCCCC1)(C2=CC=CC=C2)O.[Br-]
    InChIKey
    UKLQXHUGTKWPSR-UHFFFAOYSA-M
    InChI
    1S/C21H34NO3.BrH/c1-4-22(3,5-2)16-17-25-20(23)21(24,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6,8-9,12-13,19,24H,4-5,7,10-11,14-17H2,1-3H3;1H/q+1;/p-1
    Synonyms
    DTXSID4045632 | OXYPHENONIUM BROMIDE (MART.) | Spasmophen | Z1544404024 | EINECS 200-010-7 | Antrenyl bromide | Oxyph...
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Frequently Asked Questions

How is the mAChR listing put together?
It draws on reported mAChR annotations within GPCR/G Protein and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a mAChR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the mAChR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for mAChR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For mAChR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the mAChR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of mAChR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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