MALT1

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  1. MI 2
    CAS: 1047953-91-2 Formula: C19H17Cl3N4O3 Molecular Weight: 455.72
    ● In Stock — US warehouse, ships to EU* Item #: M276284
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    IUPAC Name
    2-chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1,2,4-triazol-1-yl]phenyl]acetamide
    SMILES
    COCCOC1=NN(C(=N1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)NC(=O)CCl
    InChIKey
    TWJGQZBSEMDPQP-UHFFFAOYSA-N
    InChI
    1S/C19H17Cl3N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7,10H,8-9,11H2,1H3,(H,23,27)
    Synonyms
    2-Chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenyl]acetamide | MI-2 (MALT1 inhibi...
  2. JNJ-67856633, Inhibitor of Janus kinase 2;Inhibitor of MALT1 paracaspase
    CAS: 2230273-76-2 Formula: C20H11F6N5O2 Molecular Weight: 467.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: J420001
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    IUPAC Name
    1-(1-oxo-2H-isoquinolin-5-yl)-5-(trifluoromethyl)-N-[2-(trifluoromethyl)pyridin-4-yl]pyrazole-4-carboxamide
    SMILES
    C1=CC2=C(C=CNC2=O)C(=C1)N3C(=C(C=N3)C(=O)NC4=CC(=NC=C4)C(F)(F)F)C(F)(F)F
    InChIKey
    APWRZPQBPCAXFP-UHFFFAOYSA-N
    InChI
    1S/C20H11F6N5O2/c21-19(22,23)15-8-10(4-6-27-15)30-18(33)13-9-29-31(16(13)20(24,25)26)14-3-1-2-12-11(14)5-7-28-17(12)32/h1-9H,(H,28,32)(H,27,30,33)
    Synonyms
    APWRZPQBPCAXFP-UHFFFAOYSA-N | SAFIMALTIB [INN] | safimaltib | SCHEMBL23417687 | 1-(1-Oxo-1,2-dihydro-5-isoquinolyl)-5...
  3. MI 2
    CAS: 1047953-91-2 Formula: C19H17Cl3N4O3 Molecular Weight: 455.72
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M420460
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    Technical Identifiers
    IUPAC Name
    2-chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1,2,4-triazol-1-yl]phenyl]acetamide
    SMILES
    COCCOC1=NN(C(=N1)C2=CC(=C(C=C2)Cl)Cl)C3=CC=C(C=C3)NC(=O)CCl
    InChIKey
    TWJGQZBSEMDPQP-UHFFFAOYSA-N
    InChI
    1S/C19H17Cl3N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7,10H,8-9,11H2,1H3,(H,23,27)
    Synonyms
    2-Chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenyl]acetamide
  4. MLT-748
    CAS: 1832578-30-9 PubChem CID: 129072285 Formula: C19H19Cl2N9O3 Molecular Weight: 492.32
    ● In Stock — US warehouse, ships to EU* Item #: M414254
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    Technical Identifiers
    IUPAC Name
    1-[2-chloro-7-[(1R,2R)-1,2-dimethoxypropyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-chloro-6-(triazol-2-yl)pyridin-3-yl]urea
    SMILES
    CC(C(C1=C(C=NC2=CC(=NN21)Cl)NC(=O)NC3=CC(=C(N=C3)N4N=CC=N4)Cl)OC)OC
    InChIKey
    XKQLNDPUQSZBJW-QGHHPUGFSA-N
    InChI
    1S/C19H19Cl2N9O3/c1-10(32-2)17(33-3)16-13(9-22-15-7-14(21)28-29(15)16)27-19(31)26-11-6-12(20)18(23-8-11)30-24-4-5-25-30/h4-10,17H,1-3H3,(H2,26,27,31)/show more
    Synonyms
    Urea,N-​[2-​chloro-​7-​[(1R,​2R)​-​1,​2-​dimethoxypropyl]​pyrazolo[1,​5-​a]​pyrimidin-​6-​yl]​-​N'-​[5-​chloro-​6-​(2H-...
  5. Z-VRPR-FMK(TFA)
    CAS: 1381885-28-4(free base) Formula: C31H49FN10O6 . C2HF3O2 Molecular Weight: 790.81
    Solid ≥90%
    ◐ .Made to order · 8–12 wks Item #: V275362
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    Technical Identifiers
    Synonyms
    MALT1 Inhibitor | Z-Val-Arg-Pro-DL-Arg-FMK(TFA) | VRPR
  6. MLT-943
    CAS: 1832576-04-1 PubChem CID: 118540057 Formula: C16H14ClF3N6O2 Molecular Weight: 414.77
    ◐ .Made to order · 8–12 wks Item #: M648386
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    Technical Identifiers
    IUPAC Name
    1-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[2-(trifluoromethyl)pyridin-4-yl]urea
    SMILES
    CC(C1=C(C=NC2=CC(=NN21)Cl)NC(=O)NC3=CC(=NC=C3)C(F)(F)F)OC
    InChIKey
    ZMPUACZRXUZAJD-QMMMGPOBSA-N
    InChI
    1S/C16H14ClF3N6O2/c1-8(28-2)14-10(7-22-13-6-12(17)25-26(13)14)24-15(27)23-9-3-4-21-11(5-9)16(18,19)20/h3-8H,1-2H3,(H2,21,23,24,27)/t8-/m0/s1
  7. MLT-747
    CAS: 2097853-86-4 PubChem CID: 129117094 Formula: C20H21Cl2N7O3 Molecular Weight: 478.33
    ◐ .Made to order · 8–12 wks Item #: M647585
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    Technical Identifiers
    IUPAC Name
    1-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-3-[5-chloro-6-(pyrrolidine-1-carbonyl)pyridin-3-yl]urea
    SMILES
    CC(C1=C(C=NC2=CC(=NN21)Cl)NC(=O)NC3=CC(=C(N=C3)C(=O)N4CCCC4)Cl)OC
    InChIKey
    OJTGJRAKRGEDPI-NSHDSACASA-N
    InChI
    1S/C20H21Cl2N7O3/c1-11(32-2)18-14(10-23-16-8-15(22)27-29(16)18)26-20(31)25-12-7-13(21)17(24-9-12)19(30)28-5-3-4-6-28/h7-11H,3-6H2,1-2H3,(H2,25,26,31)/show more
  8. Mepazine hydrochloride
    CAS: 2975-36-2 EC Number: 221-020-8 PubChem CID: 102907 Formula: C19H23ClN2S Molecular Weight: 346.92
    ◐ .Made to order · 8–12 wks Item #: M651959
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    Technical Identifiers
    IUPAC Name
    10-[(1-methylpiperidin-3-yl)methyl]phenothiazine;hydrochloride
    SMILES
    CN1CCCC(C1)CN2C3=CC=CC=C3SC4=CC=CC=C42.Cl
    InChIKey
    RLCFKYRNUBRPIK-UHFFFAOYSA-N
    InChI
    1S/C19H22N2S.ClH/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21;/h2-5,8-11,15H,6-7,12-14H2,1H3;1H
    Synonyms
    BENZOTHIAZOLE, 1-(P-AMINOPHENYL)-5-METHYL- | NSC64076 | NSC-64076 | Q27289984 | (Acetyloxy)(5-nitro-2-furyl)methyl ac...
  9. Mepazine, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 inhibitor
    CAS: 60-89-9 Formula: C19H22N2S Molecular Weight: 310.46
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: M668738
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    10-[(1-methylpiperidin-3-yl)methyl]phenothiazine
    SMILES
    CN1CCCC(C1)CN2C3=CC=CC=C3SC4=CC=CC=C42
    InChIKey
    CBHCDHNUZWWAPP-UHFFFAOYSA-N
    InChI
    1S/C19H22N2S/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21/h2-5,8-11,15H,6-7,12-14H2,1H3
    Synonyms
    Pacatal Base | Lacumin | MEPAZINE | Mepazine Base | Pakatal | mepasin | MPMP | CAS-60-89-9 | Pacatal | Paxital | (N-M...
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

Which compounds are listed for MALT1?
Compounds associated with MALT1 are grouped here under the Metabolic Enzyme/Protease classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does MALT1 sit within Metabolic Enzyme/Protease?
MALT1 is one target listing within the Metabolic Enzyme/Protease classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from MALT1?
For compounds listed under MALT1, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for MALT1?
Browse the parent Metabolic Enzyme/Protease listing to reach targets neighbouring MALT1, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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