Melatonin Receptor

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  1. Luzindole, Antagonist of MT 1 receptor;Antagonist of MT 2 receptor
    CAS: 117946-91-5 Formula: C19H20N2O Molecular Weight: 292.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ● In Stock — US warehouse, ships to EU* Item #: L132758
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    IUPAC Name
    N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide
    SMILES
    CC(=O)NCCC1=C(NC2=CC=CC=C21)CC3=CC=CC=C3
    InChIKey
    WVVXBPKOIZGVNS-UHFFFAOYSA-N
    InChI
    1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)
    Synonyms
    2-Benzyl-N-acetyltryptamine | HMS3411B10 | N-(2-(2-(PHENYLMETHYL)-1H-INDOL-3-YL)ETHYL)ETHANAMIDE | AM20020263 | Q6706...
  2. Melatonin, Antagonist of 5-HT 2B receptor;Agonist of MT 1 receptor;Agonist of MT 2 receptor
    CAS: 73-31-4 EC Number: 200-797-7 Formula: C13H16N2O2 Molecular Weight: 232.28
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: M118674
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    IUPAC Name
    N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
    SMILES
    CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC
    InChIKey
    DRLFMBDRBRZALE-UHFFFAOYSA-N
    InChI
    1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)
    Synonyms
    N-Acetyl-5-methoxytryptamine
  3. N-Acetyltryptamine
    CAS: 1016-47-3 Formula: C12H14N2O Molecular Weight: 202.26
    ● In Stock — US warehouse, ships to EU* Item #: N159539
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    IUPAC Name
    N-[2-(1H-indol-3-yl)ethyl]acetamide
    SMILES
    CC(=O)NCCC1=CNC2=CC=CC=C21
    InChIKey
    NVUGEQAEQJTCIX-UHFFFAOYSA-N
    InChI
    1S/C12H14N2O/c1-9(15)13-7-6-10-8-14-12-5-3-2-4-11(10)12/h2-5,8,14H,6-7H2,1H3,(H,13,15)
    Synonyms
    Acetamide,N-[2-(1H-indol-3-yl)ethyl]- | BRD-K73700643-001-04-7 | MLS001250169 | NCGC00024552-03 | AKOS040759465 | ISU...
  4. Agomelatine, Serotonin 2c (5-HT2c) receptor antagonist
    CAS: 138112-76-2 EC Number: 629-727-7 Formula: C15H17NO2 Molecular Weight: 243.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: A124691
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    IUPAC Name
    N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
    SMILES
    CC(=O)NCCC1=CC=CC2=C1C=C(C=C2)OC
    InChIKey
    YJYPHIXNFHFHND-UHFFFAOYSA-N
    InChI
    1S/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17)
    Synonyms
    Agomelatine [INN:BAN] | F0001-2383 | HMS3654B07 | N-(2-(7-Methoxynaphth-1-yl)ethyl)acetamide | Q-102507 | Acetamide, ...
  5. DH 97, Antagonist of MT 2 receptor
    CAS: 220339-00-4 Formula: C22H26N2O Molecular Weight: 334.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: D287006
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    IUPAC Name
    N-[2-(2-benzyl-1H-indol-3-yl)ethyl]pentanamide
    SMILES
    CCCCC(=O)NCCC1=C(NC2=CC=CC=C21)CC3=CC=CC=C3
    InChIKey
    HDOIPCLEKCEANF-UHFFFAOYSA-N
    InChI
    1S/C22H26N2O/c1-2-3-13-22(25)23-15-14-19-18-11-7-8-12-20(18)24-21(19)16-17-9-5-4-6-10-17/h4-12,24H,2-3,13-16H2,1H3,(H,23,25)
    Synonyms
    N-pentanoyl 2-benzyltryptamine | Q27077041 | HMS3267D11 | Pentanoic acid [2-(2-benzyl-1H-indol-3-yl)-ethyl]-amide | D...
  6. 8-M-PDOT
    CAS: 134865-70-6 Formula: C14H19NO2 Molecular Weight: 233.31
    ◐ .Made to order · 8–12 wks Item #: M286683
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    IUPAC Name
    N-(8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide
    SMILES
    CCC(=O)NC1CCC2=C(C1)C(=CC=C2)OC
    InChIKey
    RVIGBTUDFAGRTQ-UHFFFAOYSA-N
    InChI
    1S/C14H19NO2/c1-3-14(16)15-11-8-7-10-5-4-6-13(17-2)12(10)9-11/h4-6,11H,3,7-9H2,1-2H3,(H,15,16)
    Synonyms
    8-Methoxy-2-propionamidotetralin
  7. DH 97
    CAS: 343263-95-6 Formula: C22H26N2O Molecular Weight: 334.46
    ◐ .Made to order · 8–12 wks Item #: D339863
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    Technical Identifiers
    IUPAC Name
    N-[2-(2-benzyl-1H-indol-3-yl)ethyl]pentanamide
    SMILES
    CCCCC(=O)NCCC1=C(NC2=CC=CC=C21)CC3=CC=CC=C3
    InChIKey
    HDOIPCLEKCEANF-UHFFFAOYSA-N
    InChI
    1S/C22H26N2O/c1-2-3-13-22(25)23-15-14-19-18-11-7-8-12-20(18)24-21(19)16-17-9-5-4-6-10-17/h4-12,24H,2-3,13-16H2,1H3,(H,23,25)
    Synonyms
    N-pentanoyl 2-benzyltryptamine | Q27077041 | HMS3267D11 | Pentanoic acid [2-(2-benzyl-1H-indol-3-yl)-ethyl]-amide | D...
  8. tasimelteon, Melatonin receptor agonist
    CAS: 609799-22-6 EC Number: 612-059-5 PubChem CID: 10220503 Formula: C15H19NO2 Molecular Weight: 245.322
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: T176929
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    IUPAC Name
    N-[[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl]propanamide
    SMILES
    CCC(=O)NCC1CC1C2=C3CCOC3=CC=C2
    InChIKey
    PTOIAAWZLUQTIO-GXFFZTMASA-N
    InChI
    1S/C15H19NO2/c1-2-15(17)16-9-10-8-13(10)11-4-3-5-14-12(11)6-7-18-14/h3-5,10,13H,2,6-9H2,1H3,(H,16,17)/t10-,13+/m0/s1
    Synonyms
    SB40737 | NSC-157318 | Tasimelteon [USAN] | Tasimelteon [USAN:INN] | Hetlioz | BMS-214778;VEC-162 | CHEBI:79042 | Tas...
  9. 6-Chloromelatonin, Agonist of MT 1 receptor;Agonist of MT 2 receptor
    CAS: 63762-74-3 EC Number: 636-315-0 Formula: C13H15ClN2O2 Molecular Weight: 266.73
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: C288328
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    Technical Identifiers
    IUPAC Name
    N-[2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl]acetamide
    SMILES
    CC(=O)NCCC1=CNC2=CC(=C(C=C21)OC)Cl
    InChIKey
    LUINDDOUWHRIPW-UHFFFAOYSA-N
    InChI
    1S/C13H15ClN2O2/c1-8(17)15-4-3-9-7-16-12-6-11(14)13(18-2)5-10(9)12/h5-7,16H,3-4H2,1-2H3,(H,15,17)
    Synonyms
    NCGC00024593-01 | SR-01000075735 | BRN 0410191 | HMS3374G08 | n-[2-(6-chloro-5-methoxy-1h-indol-3-yl)ethyl]acetamide ...
  10. Ramelteon, Melatonin receptor agonist
    CAS: 196597-26-9 EC Number: 200-835-2 PubChem CID: 208902 Formula: C16H21NO2 Molecular Weight: 259.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: R125051
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    Technical Identifiers
    IUPAC Name
    N-[2-[(8S)-2,6,7,8-tetrahydro-1H-cyclopenta[e][1]benzofuran-8-yl]ethyl]propanamide
    SMILES
    CCC(=O)NCCC1CCC2=C1C3=C(C=C2)OCC3
    InChIKey
    YLXDSYKOBKBWJQ-LBPRGKRZSA-N
    InChI
    1S/C16H21NO2/c1-2-15(18)17-9-7-12-4-3-11-5-6-14-13(16(11)12)8-10-19-14/h5-6,12H,2-4,7-10H2,1H3,(H,17,18)/t12-/m0/s1
    Synonyms
    TAK-375 | MLS003915619 | N-{2-[(8S)-1H,2H,6H,7H,8H-INDENO[5,4-B]FURAN-8-YL]ETHYL}PROPANAMIDE | PROPANAMIDE, N-(2-((8S...
  11. 2-Iodomelatonin, Agonist of MT 1 receptor;Agonist of MT 2 receptor
    CAS: 93515-00-5 Formula: C13H15IN2O2 Molecular Weight: 358.18
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: I287335
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    Technical Identifiers
    IUPAC Name
    N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide
    SMILES
    CC(=O)NCCC1=C(NC2=C1C=C(C=C2)OC)I
    InChIKey
    FJDDSMSDZHURBJ-UHFFFAOYSA-N
    InChI
    1S/C13H15IN2O2/c1-8(17)15-6-5-10-11-7-9(18-2)3-4-12(11)16-13(10)14/h3-4,7,16H,5-6H2,1-2H3,(H,15,17)
    Synonyms
    2-Iodomelatonin | 2-iodo-melatonin | Tocris-0737 | EU-0100610 | Lopac-I-1899 | BRD-K25649279-001-01-2 | GTPL1343 | To...
  12. UCM 608
    CAS: 151889-03-1 PubChem CID: 4018512 Formula: C19H20N2O2 Molecular Weight: 308.38
    ● In Stock — US warehouse, ships to EU* Item #: P288352
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    Technical Identifiers
    IUPAC Name
    N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide
    SMILES
    CC(=O)NCCC1=C(NC2=C1C=C(C=C2)OC)C3=CC=CC=C3
    InChIKey
    OFCLARYYBGKCHN-UHFFFAOYSA-N
    InChI
    1S/C19H20N2O2/c1-13(22)20-11-10-16-17-12-15(23-2)8-9-18(17)21-19(16)14-6-4-3-5-7-14/h3-9,12,21H,10-11H2,1-2H3,(H,20,22)
    Synonyms
    UCM608;UCM-608 | CHEBI:107661 | Q27185983 | UCM 608 | N-[2-(5-METHOXY-2-PHENYLINDOL-3-YL)ETHYL]ACETAMIDE | AM20030035...
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Frequently Asked Questions

How is the Melatonin Receptor listing put together?
It draws on reported Melatonin Receptor annotations within Neuronal Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Melatonin Receptor modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Melatonin Receptor entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Melatonin Receptor compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Melatonin Receptor work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Melatonin Receptor compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Melatonin Receptor compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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