MetAP

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  1. 5-Methyl-2-pyridin-2-yl-1H-benzoimidazole
    CAS: 7471-12-7 Formula: C13H11N3 Molecular Weight: 209.25
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: M425806
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    Technical Identifiers
    IUPAC Name
    6-methyl-2-pyridin-2-yl-1H-benzimidazole
    SMILES
    CC1=CC2=C(C=C1)N=C(N2)C3=CC=CC=N3
    InChIKey
    HFYFOFMVURXVSD-UHFFFAOYSA-N
    InChI
    1S/C13H11N3/c1-9-5-6-10-12(8-9)16-13(15-10)11-4-2-3-7-14-11/h2-8H,1H3,(H,15,16)
    Synonyms
    5-methyl-2-pyridin-2-yl-1(3)H-benzoimidazole | UNII-9RVR7V4EAG | 6-methyl-2-pyridin-2-yl-1H-benzimidazole | 6-methyl-...
  2. Ebelactone A
    CAS: 76808-16-7 Formula: C20H34O4 Molecular Weight: 338.48
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: E329503
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    IUPAC Name
    4-[(E)-9-hydroxy-4,6,8,10-tetramethyl-7-oxododec-4-en-2-yl]-3-methyloxetan-2-one
    SMILES
    CCC(C)C(C(C)C(=O)C(C)C=C(C)CC(C)C1C(C(=O)O1)C)O
    InChIKey
    WOISDAHQBUYEAF-PKNBQFBNSA-N
    InChI
    1S/C20H34O4/c1-8-12(3)17(21)15(6)18(22)13(4)9-11(2)10-14(5)19-16(7)20(23)24-19/h9,12-17,19,21H,8,10H2,1-7H3/b11-9+
    Synonyms
    Ebelactone A microbial | NSC335650 | NSC-335650 | SCHEMBL10021628 | (3S,4S)-4-[(E,2S,6R,8S,9R,10R)-9-hydroxy-4,6,8,10...
  3. 5-Methyl-2-pyridin-2-yl-1H-benzoimidazole
    CAS: 7471-12-7 Formula: C13H11N3 Molecular Weight: 209.25
    ● In Stock — US warehouse, ships to EU* Item #: W417054
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    Technical Identifiers
    IUPAC Name
    6-methyl-2-pyridin-2-yl-1H-benzimidazole
    SMILES
    CC1=CC2=C(C=C1)N=C(N2)C3=CC=CC=N3
    InChIKey
    HFYFOFMVURXVSD-UHFFFAOYSA-N
    InChI
    1S/C13H11N3/c1-9-5-6-10-12(8-9)16-13(15-10)11-4-2-3-7-14-11/h2-8H,1H3,(H,15,16)
    Synonyms
    5-methyl-2-pyridin-2-yl-1(3)H-benzoimidazole | UNII-9RVR7V4EAG | 6-methyl-2-pyridin-2-yl-1H-benzimidazole | 6-methyl-...
  4. beloranib, Methionine aminopeptidase 2 inhibitor
    CAS: 251111-30-5 PubChem CID: 6918502 Formula: C29H41NO6 Molecular Weight: 499.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: B607980
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    Technical Identifiers
    IUPAC Name
    [(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] (E)-3-[4-[2-(dimethylamino)ethoxy]phenyl]prshow more
    SMILES
    CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC4=CC=C(C=C4)OCCN(C)C)OC)C
    InChIKey
    ZEZFKUBILQRZCK-MJSCXXSSSA-N
    InChI
    1S/C29H41NO6/c1-20(2)7-13-24-28(3,36-24)27-26(32-6)23(15-16-29(27)19-34-29)35-25(31)14-10-21-8-11-22(12-9-21)33-18-17-30(4)5/h7-12,14,23-24,26-27H,13,show more
    Synonyms
    [(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] (E)-3-[4-(...
  5. Metapro
    CAS: 431077-35-9 PubChem CID: 6918653 Formula: C22H36N2O6 Molecular Weight: 424.5
    ◐ .Made to order · 8–12 wks Item #: M668988
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    Technical Identifiers
    IUPAC Name
    [(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] N-[(2R)-1-amino-3-methyl-1-oxobutan-2-yl]cashow more
    SMILES
    CC(C)C(C(=O)N)NC(=O)OC1CCC2(CO2)C(C1OC)C3(C(O3)CC=C(C)C)C
    InChIKey
    QBDVVYNLLXGUGN-XGTBZJOHSA-N
    InChI
    1S/C22H36N2O6/c1-12(2)7-8-15-21(5,30-15)18-17(27-6)14(9-10-22(18)11-28-22)29-20(26)24-16(13(3)4)19(23)25/h7,13-18H,8-11H2,1-6H3,(H2,23,25)(H,24,26)/t1show more
    Synonyms
    PPI-2458 | Metapro | UNII-NA0Y2SRR29 | PPI 2458 | NA0Y2SRR29 | Carbamic acid, ((1R)-1-(aminocarbonyl)-2-methylpropyl)...
  6. 4-(4-bromophenyl)-1H-1,2,3-triazole
    CAS: 5301-98-4 Formula: C8H6BrN3 Molecular Weight: 224.06
    ◐ .Made to order · 8–12 wks Item #: B668962
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    Technical Identifiers
    IUPAC Name
    4-(4-bromophenyl)-2H-triazole
    SMILES
    C1=CC(=CC=C1C2=NNN=C2)Br
    InChIKey
    RYKZCPFWGNDOQV-UHFFFAOYSA-N
    InChI
    1S/C8H6BrN3/c9-7-3-1-6(2-4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)
    Synonyms
    4-(4-bromophenyl)-1H-1,2,3-triazole | MetAP2-IN-1 | 5-(4-bromophenyl)-1H-1,2,3-triazole | 1H-1,2,3-Triazole, 4-(4-bro...
  7. Aclimostat, Methionine aminopeptidase 2 inhibitor
    CAS: 2082752-83-6 PubChem CID: 126573394 Formula: C26H42N2O6 Molecular Weight: 478.6
    ◐ .Made to order · 8–12 wks Item #: A671327
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    Technical Identifiers
    IUPAC Name
    [(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] 3-(2-morpholin-4-ylethyl)azetidine-1-carboxshow more
    SMILES
    CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)N4CC(C4)CCN5CCOCC5)OC)C
    InChIKey
    QJWJPMLDQYEPPW-AUKZVGPFSA-N
    InChI
    1S/C26H42N2O6/c1-18(2)5-6-21-25(3,34-21)23-22(30-4)20(7-9-26(23)17-32-26)33-24(29)28-15-19(16-28)8-10-27-11-13-31-14-12-27/h5,19-23H,6-17H2,1-4H3/t20-show more
    Synonyms
    Aclimostat | BDBM148432 | (3R,4S,5S,6R)5Methoxy4((2R,3R)2methyl3(3methylbut2en1yl)oxiran2yl)1oxaspiro(2.5)octan6yl 3(...
  8. Beloranib hemioxalate
    CAS: 529511-79-3 PubChem CID: 71811218 Formula: C29H41NO6•/C2H2O4 Molecular Weight: 544.66
    ◐ .Made to order · 8–12 wks Item #: B1442610
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    Technical Identifiers
    IUPAC Name
    [(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl] (E)-3-[4-[2-(dimethylamino)ethoxy]phenyl]prshow more
    SMILES
    CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC4=CC=C(C=C4)OCCN(C)C)OC)C.C(=O)(C(=O)O)O
    InChIKey
    OBFUDFUBQNPMRQ-FTIILNKYSA-N
    InChI
    1S/C29H41NO6.C2H2O4/c1-20(2)7-13-24-28(3,36-24)27-26(32-6)23(15-16-29(27)19-34-29)35-25(31)14-10-21-8-11-22(12-9-21)33-18-17-30(4)5;3-1(4)2(5)6/h7-12,show more
  9. M8891
    CAS: 1464842-09-8 PubChem CID: 89855776
    ◐ .Made to order · 8–12 wks Item #: M1442616
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    Technical Identifiers
    IUPAC Name
    (3S)-N-[(3,5-difluorophenyl)methyl]-3-hydroxy-1-(1H-indol-5-yl)-2-oxopyrrolidine-3-carboxamide
    SMILES
    C1CN(C(=O)C1(C(=O)NCC2=CC(=CC(=C2)F)F)O)C3=CC4=C(C=C3)NC=C4
    InChIKey
    WVGGJQVCOTYFPV-FQEVSTJZSA-N
    InChI
    1S/C20H17F2N3O3/c21-14-7-12(8-15(22)10-14)11-24-18(26)20(28)4-6-25(19(20)27)16-1-2-17-13(9-16)3-5-23-17/h1-3,5,7-10,23,28H,4,6,11H2,(H,24,26)/t20-/m0/show more
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Frequently Asked Questions

How is the MetAP listing put together?
It draws on reported MetAP annotations within Metabolic Enzyme/Protease and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MetAP modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MetAP entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MetAP compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MetAP work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MetAP compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MetAP compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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