Methylenetetrahydrofolate Dehydrogenase (MTHFD)

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  1. DS44960156
    CAS: 2361327-08-2 PubChem CID: 138393352 Formula: C20H15NO5 Molecular Weight: 349.34
    ◐ .Made to order · 8–12 wks Item #: D646229
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    Technical Identifiers
    IUPAC Name
    4-(5-oxo-2,4-dihydro-1H-chromeno[3,4-c]pyridine-3-carbonyl)benzoic acid
    SMILES
    C1CN(CC2=C1C3=CC=CC=C3OC2=O)C(=O)C4=CC=C(C=C4)C(=O)O
    InChIKey
    OXUKTNZACAKVRG-UHFFFAOYSA-N
    InChI
    1S/C20H15NO5/c22-18(12-5-7-13(8-6-12)19(23)24)21-10-9-14-15-3-1-2-4-17(15)26-20(25)16(14)11-21/h1-8H,9-11H2,(H,23,24)
  2. LY 345899
    CAS: 10538-99-5 Formula: C20H21N7O7 Molecular Weight: 471.42
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: L647218
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    IUPAC Name
    (2S)-2-[[4-(3-amino-1,9-dioxo-5,6,6a,7-tetrahydro-2H-imidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid
    SMILES
    C1C2CN(C(=O)N2C3=C(N1)N=C(NC3=O)N)C4=CC=C(C=C4)C(=O)NC(CCC(=O)O)C(=O)O
    InChIKey
    JSNFRYBHBVDHSG-KIYNQFGBSA-N
    InChI
    1S/C20H21N7O7/c21-19-24-15-14(17(31)25-19)27-11(7-22-15)8-26(20(27)34)10-3-1-9(2-4-10)16(30)23-12(18(32)33)5-6-13(28)29/h1-4,11-12H,5-8H2,(H,23,30)(H,show more
    Synonyms
    (2S)-2-(4-(3-Amino-1,9-dioxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl)benzamido)pentanedioic acid
  3. DS18561882
    CAS: 2227149-22-4 PubChem CID: 139486677 Formula: C28H31F3N4O6S Molecular Weight: 608.63
    ◐ .Made to order · 8–12 wks Item #: D647615
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    IUPAC Name
    N-[4-[8-[(3S)-3,4-dimethylpiperazin-1-yl]-7-methyl-5-oxo-2,4-dihydro-1H-chromeno[3,4-c]pyridine-3-carbonyl]-2-(trifluoromethoxy)phenyl]methanesulfonamshow more
    SMILES
    CC1CN(CCN1C)C2=C(C3=C(C=C2)C4=C(CN(CC4)C(=O)C5=CC(=C(C=C5)NS(=O)(=O)C)OC(F)(F)F)C(=O)O3)C
    InChIKey
    OQKAKSSZSQPTDZ-INIZCTEOSA-N
    InChI
    1S/C28H31F3N4O6S/c1-16-14-34(12-11-33(16)3)23-8-6-20-19-9-10-35(15-21(19)27(37)40-25(20)17(23)2)26(36)18-5-7-22(32-42(4,38)39)24(13-18)41-28(29,30)31/show more
  4. DS44960156
    CAS: 2361327-08-2 PubChem CID: 138393352 Formula: C20H15NO5 Molecular Weight: 349.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: D1496133
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the Methylenetetrahydrofolate Dehydrogenase (MTHFD) listing put together?
It draws on reported Methylenetetrahydrofolate Dehydrogenase (MTHFD) annotations within Metabolic Enzyme/Protease and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Methylenetetrahydrofolate Dehydrogenase (MTHFD) modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Methylenetetrahydrofolate Dehydrogenase (MTHFD) entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Methylenetetrahydrofolate Dehydrogenase (MTHFD) compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Methylenetetrahydrofolate Dehydrogenase (MTHFD) work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Methylenetetrahydrofolate Dehydrogenase (MTHFD) compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Methylenetetrahydrofolate Dehydrogenase (MTHFD) compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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