mGluR

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  1. L-CCG-l, Agonist of mGlu 1 receptor;Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Agonist of mGlu 4 receptor;Agonist of mGlu 5 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
    CAS: 117857-93-9 Formula: C6H9NO4 Molecular Weight: 159.14
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ◐ .Made to order · 8–12 wks Item #: L287585
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    IUPAC Name
    (1S,2S)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid
    SMILES
    C1C(C1C(=O)O)C(C(=O)O)N
    InChIKey
    GZOVEPYOCJWRFC-HZLVTQRSSA-N
    InChI
    1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3-,4-/m0/s1
    Synonyms
    AM85789 | L-CCG I | NCGC00024541-02 | SCHEMBL664330 | 2-(Amino-carboxy-methyl)-cyclopropanecarboxylic acid(2S,3S,4S-C...
  2. YM298198 hydrochloride, Allosteric modulator of mGlu 1 receptor
    CAS: 748758-45-4 PubChem CID: 9819432 Formula: C18H22N4OS.HCl Molecular Weight: 378.92
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: Y276490
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    IUPAC Name
    7-amino-N-cyclohexyl-N,1-dimethyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide
    SMILES
    CC1=C(SC2=NC3=C(N12)C=C(C=C3)N)C(=O)N(C)C4CCCCC4
    InChIKey
    KCBXOMYXOBVLED-UHFFFAOYSA-N
    InChI
    1S/C18H22N4OS/c1-11-16(17(23)21(2)13-6-4-3-5-7-13)24-18-20-14-9-8-12(19)10-15(14)22(11)18/h8-10,13H,3-7,19H2,1-2H3
    Synonyms
    6-Amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamidehydrochloride
  3. SIB 1757, Allosteric modulator of mGlu 5 receptor
    CAS: 31993-01-8 PubChem CID: 5218788 Formula: C12H11N3O Molecular Weight: 213.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S287942
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    IUPAC Name
    6-methyl-2-phenyldiazenylpyridin-3-ol
    SMILES
    CC1=NC(=C(C=C1)O)N=NC2=CC=CC=C2
    InChIKey
    LOCPVWIREQIGNQ-UHFFFAOYSA-N
    InChI
    1S/C12H11N3O/c1-9-7-8-11(16)12(13-9)15-14-10-5-3-2-4-6-10/h2-8,16H,1H3
    Synonyms
    NCGC00185991-01 | CHEBI:93722 | SR-01000076142-1 | BCP33033 | BDBM50478347 | DTXSID00425754 | EU-0101161 | CCG-205235...
  4. SIB 1893, Allosteric modulator of mGlu 4 receptor;Allosteric modulator of mGlu 5 receptor
    CAS: 6266-99-5 EC Number: 635-306-9 PubChem CID: 5311432 Formula: C14H13N Molecular Weight: 195.26
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S286680
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    IUPAC Name
    2-methyl-6-[(E)-2-phenylethenyl]pyridine
    SMILES
    CC1=NC(=CC=C1)C=CC2=CC=CC=C2
    InChIKey
    SISOFUCTXZKSOQ-ZHACJKMWSA-N
    InChI
    1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+
    Synonyms
    (E/Z)-SIB-1893 | 2-Methyl-6-styryl-pyridine(SIB-1893) | AKOS006279967 | BDBM86715 | HY-102094 | 2-Methyl-6-((E)-styry...
  5. MNI 137, Allosteric modulator of mGlu 2 receptor;Allosteric modulator of mGlu 3 receptor
    CAS: 946619-21-2 Formula: C15H9BrN4O Molecular Weight: 341.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ◐ .Made to order · 8–12 wks Item #: M288647
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    IUPAC Name
    4-(8-bromo-2-oxo-1,3-dihydro-1,5-benzodiazepin-4-yl)pyridine-2-carbonitrile
    SMILES
    C1C(=NC2=C(C=C(C=C2)Br)NC1=O)C3=CC(=NC=C3)C#N
    InChIKey
    KMKZCMKOSAKVGY-UHFFFAOYSA-N
    InChI
    1S/C15H9BrN4O/c16-10-1-2-12-14(6-10)20-15(21)7-13(19-12)9-3-4-18-11(5-9)8-17/h1-6H,7H2,(H,20,21)
    Synonyms
    4-(8-Bromo-2,3-dihydro-2-oxo-1H-1,5-benzodiazepin-4-yl)-2-pyridinecarbonitrile | 4-(7-bromo-4-hydroxy-3H-benzo[b][1,4...
  6. MSOP, Antagonist of mGlu 2 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu 8 receptor
    CAS: 66515-29-5 EC Number: 809-692-6 Formula: C4H10NO6P Molecular Weight: 199.1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: M275068
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    IUPAC Name
    2-amino-2-methyl-3-phosphonooxypropanoic acid
    SMILES
    CC(COP(=O)(O)O)(C(=O)O)N
    InChIKey
    GSFCOAGADOGIGE-UHFFFAOYSA-N
    InChI
    1S/C4H10NO6P/c1-4(5,3(6)7)2-11-12(8,9)10/h2,5H2,1H3,(H,6,7)(H2,8,9,10)
    Synonyms
    (RS)-?-Methylserine-O-phosphate | 2-AMINO-2-METHYL-3-(PHOSPHONOOXY)PROPANOIC ACID | DTXSID40398271 | Q27074406 | alph...
  7. LSN2463359, Allosteric modulator of mGlu 5 receptor
    CAS: 1401031-52-4 EC Number: 802-759-0 Formula: C16H15N3O Molecular Weight: 265.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: L167188
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    IUPAC Name
    N-propan-2-yl-5-(2-pyridin-4-ylethynyl)pyridine-2-carboxamide
    SMILES
    CC(C)NC(=O)C1=NC=C(C=C1)C#CC2=CC=NC=C2
    InChIKey
    STAFRSGTRKNXHF-UHFFFAOYSA-N
    InChI
    1S/C16H15N3O/c1-12(2)19-16(20)15-6-5-14(11-18-15)4-3-13-7-9-17-10-8-13/h5-12H,1-2H3,(H,19,20)
    Synonyms
    BGC03152 | GTPL6394 | 2-Pyridinecarboxamide, N-(1-methylethyl)-5-[2-(4-pyridinyl)ethynyl]- | N-Isopropyl-5-(pyridin-4...
  8. JNJ 16259685, Allosteric modulator of mGlu 1 receptor
    CAS: 409345-29-5 Formula: C20H23NO3 Molecular Weight: 325.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ● In Stock — US warehouse, ships to EU* Item #: J287450
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    IUPAC Name
    3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl-(4-methoxycyclohexyl)methanone
    SMILES
    COC1CCC(CC1)C(=O)C2=CC3=CC4=C(N=C3C=C2)OCCC4
    InChIKey
    QOTAQTRFJWLFCR-UHFFFAOYSA-N
    InChI
    1S/C20H23NO3/c1-23-17-7-4-13(5-8-17)19(22)14-6-9-18-16(11-14)12-15-3-2-10-24-20(15)21-18/h6,9,11-13,17H,2-5,7-8,10H2,1H3
    Synonyms
    J-110 | (3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl)(4-methoxycyclohexyl)methanone | HB0348 | NCGC00092375-01 | CHEBI:...
  9. VU 0361737, Allosteric modulator of mGlu 4 receptor
    CAS: 1161205-04-4 EC Number: 802-357-5 PubChem CID: 44191096 Formula: C13H11ClN2O2 Molecular Weight: 262.69
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: V129527
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    IUPAC Name
    N-(4-chloro-3-methoxyphenyl)pyridine-2-carboxamide
    SMILES
    COC1=C(C=CC(=C1)NC(=O)C2=CC=CC=N2)Cl
    InChIKey
    ARYUXFNGXHNNDM-UHFFFAOYSA-N
    InChI
    1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
    Synonyms
    AC-32871 | VU 0361737 | VU0361737 | VU-0361737 | J-003384 | AKOS024457762 | BCP06488 | Benzo-1,4-quinone dioxime # | ...
  10. VU 0364770, Allosteric modulator of mGlu 4 receptor
    CAS: 61350-00-3 EC Number: 111-965-3 PubChem CID: 836002 Formula: C12H9ClN2O Molecular Weight: 232.67
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: V129525
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    Technical Identifiers
    IUPAC Name
    N-(3-chlorophenyl)pyridine-2-carboxamide
    SMILES
    C1=CC=NC(=C1)C(=O)NC2=CC(=CC=C2)Cl
    InChIKey
    SUYUTNCKIOLMAJ-UHFFFAOYSA-N
    InChI
    1S/C12H9ClN2O/c13-9-4-3-5-10(8-9)15-12(16)11-6-1-2-7-14-11/h1-8H,(H,15,16)
    Synonyms
    HY-100588 | HMS3884L20 | VU 0364770 | N-(3-chloro-phenyl)-pyridine-2-carboxamide | N-(3-chlorophenyl)pyridine-2-carbo...
  11. VU 0409551, Allosteric modulator of mGlu 5 receptor
    CAS: 1363281-27-9 PubChem CID: 56846694 Formula: C20H17FN2O3 Molecular Weight: 352.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: V288400
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    IUPAC Name
    (4-fluorophenyl)-[2-(phenoxymethyl)-6,7-dihydro-4H-[1,3]oxazolo[5,4-c]pyridin-5-yl]methanone
    SMILES
    C1CN(CC2=C1N=C(O2)COC3=CC=CC=C3)C(=O)C4=CC=C(C=C4)F
    InChIKey
    QUZLMKNNIUSREV-UHFFFAOYSA-N
    InChI
    1S/C20H17FN2O3/c21-15-8-6-14(7-9-15)20(24)23-11-10-17-18(12-23)26-19(22-17)13-25-16-4-2-1-3-5-16/h1-9H,10-13H2
    Synonyms
    JNJ-46778212 | VU040955 | [6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](4-fluorophenyl)methanone
  12. VU 0422288, Allosteric modulator of mGlu 8 receptor
    CAS: 1630936-95-6 PubChem CID: 73058507 Formula: C17H11Cl2N3O2 Molecular Weight: 360.19
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: V287914
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    Technical Identifiers
    IUPAC Name
    N-[3-chloro-4-(5-chloropyridin-2-yl)oxyphenyl]pyridine-2-carboxamide
    SMILES
    C1=CC=NC(=C1)C(=O)NC2=CC(=C(C=C2)OC3=NC=C(C=C3)Cl)Cl
    InChIKey
    MZRLPXFGQKQHST-UHFFFAOYSA-N
    InChI
    1S/C17H11Cl2N3O2/c18-11-4-7-16(21-10-11)24-15-6-5-12(9-13(15)19)22-17(23)14-3-1-2-8-20-14/h1-10H,(H,22,23)
    Synonyms
    ML 396 | N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide | ML396 | N-(3-Chloro-4-((5-chloropyr...
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Frequently Asked Questions

Which compounds are listed for mGluR?
Compounds associated with mGluR are grouped here under the GPCR/G Protein classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does mGluR sit within GPCR/G Protein?
mGluR is one target listing within the GPCR/G Protein classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from mGluR?
For compounds listed under mGluR, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for mGluR?
Browse the parent GPCR/G Protein listing to reach targets neighbouring mGluR, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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