Microtubule/Tubulin

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  1. Sertaconazole nitrate, Cytochrome P450 51 inhibitor
    CAS: 99592-39-9 PubChem CID: 200103 Formula: C20H15Cl3N2OS·HNO3 Molecular Weight: 500.78
    ● In Stock — US warehouse, ships to EU* Item #: S129395
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    IUPAC Name
    1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid
    SMILES
    C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl.[N+](=O)(O)[O-]
    InChIKey
    HAAITRDZHUANGT-UHFFFAOYSA-N
    InChI
    1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4)
    Synonyms
    HMS1571A12 | CAS-99592-39-9 | A851341 | 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H...
  2. Fosbretabulin disodium, Tubulin inhibitor
    CAS: 168555-66-6 Formula: C18H19O8P·2Na Molecular Weight: 440.29
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: F129767
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    IUPAC Name
    disodium;[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] phosphate
    SMILES
    COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)OP(=O)([O-])[O-].[Na+].[Na+]
    InChIKey
    VXNQMUVMEIGUJW-XNOMRPDFSA-L
    InChI
    1S/C18H21O8P.2Na/c1-22-14-8-7-12(9-15(14)26-27(19,20)21)5-6-13-10-16(23-2)18(25-4)17(11-13)24-3;;/h5-11H,1-4H3,(H2,19,20,21);;/q;2*+1/p-2/b6-5-;;
    Synonyms
    CA 4P | CA-4P | MFCD00943911 | Zybrestat | Fosbretabulin Disodium Salt | PHENOL, 2-METHOXY-5-((1Z)-2-(3,4,5-TRIMETHOX...
  3. S-Me-DM1
    CAS: 912569-84-7 PubChem CID: 154705356 Formula: C36H50ClN3O10S Molecular Weight: 752.31
    ◐ .Made to order · 8–12 wks Item #: S276125
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    IUPAC Name
    [(1S,2R,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.0show more
    SMILES
    CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)N(C)C(=O)CCSC)C)C)OC)(NC(=O)O2)O
    InChIKey
    PLYHSTGTQYPYMT-UDXCHANISA-N
    InChI
    1S/C36H50ClN3O10S/c1-20-11-10-12-27(47-8)36(45)19-26(48-34(44)38-36)21(2)32-35(4,50-32)28(49-33(43)22(3)39(5)29(41)13-14-51-9)18-30(42)40(6)24-16-23(1show more
    Synonyms
    N2'-Deacetyl-N2'-(3-thiomethyl-1-oxopropyl)-maytansine
  4. Griseofulvin, Tubulin inhibitor
    CAS: 126-07-8 EC Number: 204-767-4 Formula: C17H17ClO6 Molecular Weight: 352.77
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: G101269
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    IUPAC Name
    (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
    SMILES
    CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
    InChIKey
    DDUHZTYCFQRHIY-RBHXEPJQSA-N
    InChI
    1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
    Synonyms
    CCRIS 320 | Grifulin | (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-...
  5. Docetaxel Trihydrate, Tubulin inhibitor
    CAS: 148408-66-6 EC Number: 642-361-2 PubChem CID: 148123 Formula: C43H59NO17 Molecular Weight: 861.9
    ● In Stock — US warehouse, ships to EU* Item #: D337470
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    IUPAC Name
    [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-1show more
    SMILES
    CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O.O.O.O
    InChIKey
    XCDIRYDKECHIPE-QHEQPUDQSA-N
    InChI
    1S/C43H53NO14.3H2O/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)2show more
    Synonyms
    (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropano...
  6. MMAF
    CAS: 745017-94-1 Formula: C39H65N5O8 Molecular Weight: 731.96
    ● In Stock — US warehouse, ships to EU* Item #: M395755
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    IUPAC Name
    (2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]show more
    SMILES
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C(=O)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC
    InChIKey
    MFRNYXJJRJQHNW-DEMKXPNLSA-N
    InChI
    1S/C39H65N5O8/c1-12-25(6)34(43(9)38(48)33(24(4)5)42-37(47)32(40-8)23(2)3)30(51-10)22-31(45)44-20-16-19-29(44)35(52-11)26(7)36(46)41-28(39(49)50)21-27-show more
    Synonyms
    MMAF | (2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl...
  7. Mebendazole, Tubulin inhibitor
    CAS: 31431-39-7 EC Number: 250-635-4 Formula: C16H13N3O3 Molecular Weight: 295.29
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: M111946
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    IUPAC Name
    methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate
    SMILES
    COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3
    InChIKey
    OPXLLQIJSORQAM-UHFFFAOYSA-N
    InChI
    1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)
    Synonyms
    81G6I5V05I | Mebendazol | NCGC00016806-01 | Verpanyl | Equivurm Plus | HSDB 3232 | MEBENDAZOLE [USP-RS] | methyl N-(6...
  8. Nocodazole
    CAS: 31430-18-9 EC Number: 250-626-5 Formula: C14H11N3O3S Molecular Weight: 301.32
    ● In Stock — US warehouse, ships to EU* Item #: N129755
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    IUPAC Name
    methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
    SMILES
    COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
    InChIKey
    KYRVNWMVYQXFEU-UHFFFAOYSA-N
    InChI
    1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)
    Synonyms
    HMS587E01 | Methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate | MLS001164242 | DTXCID7011800 | KBio3_0027...
  9. MMAD
    CAS: 203849-91-6 PubChem CID: 10723894 Formula: C41H66N6O6S Molecular Weight: 771.06
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: M125063
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    IUPAC Name
    (2S)-N-[(2S)-1-[[(3R,4S,5S)-3-methoxy-1-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino]propyl]pyrrolidin-show more
    SMILES
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC
    InChIKey
    BLUGYPPOFIHFJS-UUFHNPECSA-N
    InChI
    1S/C41H66N6O6S/c1-12-27(6)36(46(9)41(51)35(26(4)5)45-39(50)34(42-8)25(2)3)32(52-10)24-33(48)47-21-16-19-31(47)37(53-11)28(7)38(49)44-30(40-43-20-22-54show more
    Synonyms
    Monomethylauristatin D | Monomethyl Dolastatin 10 | Demethyldolastatin 10
  10. Colchicine
    CAS: 64-86-8 EC Number: 200-598-5 Formula: C22H25NO6 Molecular Weight: 399.44
    Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: C106739
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    IUPAC Name
    N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
    SMILES
    CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC
    InChIKey
    IAKHMKGGTNLKSZ-INIZCTEOSA-N
    InChI
    1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
    Synonyms
    COLBENEMID COMPONENT COLCHICINE | Colchicin | COLCHICINE [MI] | EINECS 200-598-5 | HSDB 3044 | COLCHICINE [HSDB] | CO...
  11. D-(+)-chiro-Inositol
    CAS: 643-12-9 EC Number: 211-394-0 Formula: C6H12O6 Molecular Weight: 180.16
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: D131001
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    IUPAC Name
    cyclohexane-1,2,3,4,5,6-hexol
    SMILES
    C1(C(C(C(C(C1O)O)O)O)O)O
    InChIKey
    CDAISMWEOUEBRE-UHFFFAOYSA-N
    InChI
    1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H
    Synonyms
    AZD 103 | D-chiro-Inositol | (1R,2R,3R,4S,5S,6s)-cyclohexane-1,2,3,4,5,6-hexaol | Inosite | L-Inositol | (-)-chiro-In...
  12. Oryzalin
    CAS: 19044-88-3 EC Number: 242-777-0 Formula: C12H18N4O6S Molecular Weight: 346.36
    ● In Stock — US warehouse, ships to EU* Item #: O140969
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    IUPAC Name
    4-(dipropylamino)-3,5-dinitrobenzenesulfonamide
    SMILES
    CCCN(CCC)C1=C(C=C(C=C1[N+](=O)[O-])S(=O)(=O)N)[N+](=O)[O-]
    InChIKey
    UNAHYJYOSSSJHH-UHFFFAOYSA-N
    InChI
    1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)
    Synonyms
    3,5-Dinitro-N',N'-dipropylsulfanilamide
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Frequently Asked Questions

How is the Microtubule/Tubulin listing put together?
It draws on reported Microtubule/Tubulin annotations within Cytoskeleton and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Microtubule/Tubulin modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Microtubule/Tubulin entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Microtubule/Tubulin compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Microtubule/Tubulin work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Microtubule/Tubulin compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Microtubule/Tubulin compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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