Na+/Ca2+ Exchanger

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  1. Benzamil, Channel blocker of ASIC1;Channel blocker of ENaCαβγ;Channel blocker of TRPP2
    CAS: 2898-76-2 Formula: C13H14ClN7O Molecular Weight: 319.75
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: B275880
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    IUPAC Name
    3,5-diamino-N-(N'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide
    SMILES
    C1=CC=C(C=C1)CN=C(N)NC(=O)C2=C(N=C(C(=N2)Cl)N)N
    InChIKey
    KXDROGADUISDGY-UHFFFAOYSA-N
    InChI
    1S/C13H14ClN7O/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22)
    Synonyms
    AKOS027382092 | NCGC00015147-11 | SPBio_002614 | CCG-204306 | KBio2_000300 | NCGC00015147-01 | Pyrazinecarboxamide, 3...
  2. S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate, Channel blocker of TRPC3;Channel blocker of TRPC5;Channel blocker of TRPC6
    CAS: 182004-65-5 PubChem CID: 9823846 Formula: C16H17N3O3S·CH4O3S Molecular Weight: 427.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: S161158
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    IUPAC Name
    methanesulfonic acid;2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl carbamimidothioate
    SMILES
    CS(=O)(=O)O.C1=CC(=CC=C1CCSC(=N)N)OCC2=CC=C(C=C2)[N+](=O)[O-]
    InChIKey
    WGIKEBHIKKWJLG-UHFFFAOYSA-N
    InChI
    1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4)
    Synonyms
    GTPL4232 | HY-15415 | s4643 | 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE | 2-(2-(4-(4-nitrobenzyloxy...
  3. YM-244769 dihydrochloride
    CAS: 1780390-65-9 PubChem CID: 90488952 Formula: C26H22FN3O3•2HCl Molecular Weight: 516.39
    ● In Stock — US warehouse, ships to EU* Item #: Y286782
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    IUPAC Name
    N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]pyridine-3-carboxamide;dihydrochloride
    SMILES
    C1=CC(=CC(=C1)N)CNC(=O)C2=CN=C(C=C2)OC3=CC=C(C=C3)OCC4=CC(=CC=C4)F.Cl.Cl
    InChIKey
    OCKIUNLKEPKCRE-UHFFFAOYSA-N
    InChI
    1S/C26H22FN3O3.2ClH/c27-21-5-1-4-19(13-21)17-32-23-8-10-24(11-9-23)33-25-12-7-20(16-29-25)26(31)30-15-18-3-2-6-22(28)14-18;;/h1-14,16H,15,17,28H2,(H,3show more
    Synonyms
    N-[(3-Aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-3-pyridinecarboxamide dihydrochloride
  4. Benzamil hydrochloride
    CAS: 161804-20-2 EC Number: 634-062-0 PubChem CID: 5702295 Formula: C13H14ClN7O•HCl Molecular Weight: 356.21
    ● In Stock — US warehouse, ships to EU* Item #: B287915
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    IUPAC Name
    3,5-diamino-N-(N'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide;hydrochloride
    SMILES
    C1=CC=C(C=C1)CN=C(N)NC(=O)C2=C(N=C(C(=N2)Cl)N)N.Cl
    InChIKey
    ZNWMRWWNJBXNKJ-UHFFFAOYSA-N
    InChI
    1S/C13H14ClN7O.ClH/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7;/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22);1H
    Synonyms
    Benzamil (hydrochloride) | Tox21_500211 | MLS002153937 | SR-01000075711 | SR-01000075711-4 | 3,5-diamino-6-chloro-N-[...
  5. SN6
    CAS: 415697-08-4 PubChem CID: 10222761 Formula: C20H22N2O5S Molecular Weight: 402.46
    ● In Stock — US warehouse, ships to EU* Item #: S303682
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    IUPAC Name
    ethyl 2-[[4-[(4-nitrophenyl)methoxy]phenyl]methyl]-1,3-thiazolidine-4-carboxylate
    SMILES
    CCOC(=O)C1CSC(N1)CC2=CC=C(C=C2)OCC3=CC=C(C=C3)[N+](=O)[O-]
    InChIKey
    ZVYIJXLMBWCGHP-UHFFFAOYSA-N
    InChI
    1S/C20H22N2O5S/c1-2-26-20(23)18-13-28-19(21-18)11-14-5-9-17(10-6-14)27-12-15-3-7-16(8-4-15)22(24)25/h3-10,18-19,21H,2,11-13H2,1H3
    Synonyms
    BCP32885 | Ethyl 2-(4-((4-nitrobenzyl)oxy)benzyl)thiazolidine-4-carboxylate | N16889 | BRD-A14316475-001-01-5 | HMS36...
  6. Terfenadine, Inhibitor of CYP2J2;Antagonist of H 1 receptor;Channel blocker of K v10.1;Channel blocker of K v11.1
    CAS: 50679-08-8 EC Number: 256-710-8 PubChem CID: 5405 Formula: C32H41NO2 Molecular Weight: 471.67
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: T137617
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    IUPAC Name
    1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol
    SMILES
    CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O
    InChIKey
    GUGOEEXESWIERI-UHFFFAOYSA-N
    InChI
    1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35show more
    Synonyms
    (±)-Terfenadine | MDL-991 | 1-(4-(tert-Butyl)phenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol
  7. CGP 37157, Inhibitor of Sodium/potassium/calcium exchanger 6
    CAS: 75450-34-9 EC Number: 684-725-3 Formula: C15H11Cl2NOS Molecular Weight: 324.2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: C276488
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    IUPAC Name
    7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2-one
    SMILES
    C1C(=O)NC2=C(C=C(C=C2)Cl)C(S1)C3=CC=CC=C3Cl
    InChIKey
    KQEPIRKXSUIUTH-UHFFFAOYSA-N
    InChI
    1S/C15H11Cl2NOS/c16-9-5-6-13-11(7-9)15(20-8-14(19)18-13)10-3-1-2-4-12(10)17/h1-7,15H,8H2,(H,18,19)
    Synonyms
    7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2-one | CM-119 | IDI1_034026 | Q27163475 | KBio3_000552 | ...
  8. S-[4-[(4-Nitrobenzyl)oxy]phenethyl]isothiourea Methanesulfonate, Channel blocker of TRPC3;Channel blocker of TRPC5;Channel blocker of TRPC6
    CAS: 182004-65-5 PubChem CID: 9823846 Formula: C16H17N3O3S·CH4O3S Molecular Weight: 427.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: S422233
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    Technical Identifiers
    IUPAC Name
    methanesulfonic acid;2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl carbamimidothioate
    SMILES
    CS(=O)(=O)O.C1=CC(=CC=C1CCSC(=N)N)OCC2=CC=C(C=C2)[N+](=O)[O-]
    InChIKey
    WGIKEBHIKKWJLG-UHFFFAOYSA-N
    InChI
    1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4)
    Synonyms
    GTPL4232 | HY-15415 | s4643 | 2-[2-[4-(4-NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA MESYLATE | 2-(2-(4-(4-nitrobenzyloxy...
  9. SEA0400
    CAS: 223104-29-8 PubChem CID: 644100 Formula: C21H19F2NO3 Molecular Weight: 371.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S125871
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    IUPAC Name
    2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline
    SMILES
    CCOC1=CC(=C(C=C1)OC2=CC=C(C=C2)OCC3=C(C=CC(=C3)F)F)N
    InChIKey
    YSUBLPUJDOWYDP-UHFFFAOYSA-N
    InChI
    1S/C21H19F2NO3/c1-2-25-18-8-10-21(20(24)12-18)27-17-6-4-16(5-7-17)26-13-14-11-15(22)3-9-19(14)23/h3-12H,2,13,24H2,1H3
    Synonyms
    GTPL4617 | 2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline | J-690265 | SEA0400 | SEA-0400 | SEA 0400 | DT...
  10. SN6
    CAS: 415697-08-4 PubChem CID: 10222761 Formula: C20H22N2O5S Molecular Weight: 402.46
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: S423881
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    Technical Identifiers
    IUPAC Name
    ethyl 2-[[4-[(4-nitrophenyl)methoxy]phenyl]methyl]-1,3-thiazolidine-4-carboxylate
    SMILES
    CCOC(=O)C1CSC(N1)CC2=CC=C(C=C2)OCC3=CC=C(C=C3)[N+](=O)[O-]
    InChIKey
    ZVYIJXLMBWCGHP-UHFFFAOYSA-N
    InChI
    1S/C20H22N2O5S/c1-2-26-20(23)18-13-28-19(21-18)11-14-5-9-17(10-6-14)27-12-15-3-7-16(8-4-15)22(24)25/h3-10,18-19,21H,2,11-13H2,1H3
    Synonyms
    BCP32885 | Ethyl 2-(4-((4-nitrobenzyl)oxy)benzyl)thiazolidine-4-carboxylate | N16889 | BRD-A14316475-001-01-5 | HMS36...
  11. ORM-10103
    CAS: 488847-28-5 PubChem CID: 17978512 Formula: C20H16N2O4 Molecular Weight: 348.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: O612553
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    IUPAC Name
    5-nitro-2-[(2-phenyl-3,4-dihydro-2H-chromen-6-yl)oxy]pyridine
    SMILES
    C1CC2=C(C=CC(=C2)OC3=NC=C(C=C3)[N+](=O)[O-])OC1C4=CC=CC=C4
    InChIKey
    GZONLGPIHCCJOI-UHFFFAOYSA-N
    InChI
    1S/C20H16N2O4/c23-22(24)16-7-11-20(21-13-16)25-17-8-10-19-15(12-17)6-9-18(26-19)14-4-2-1-3-5-14/h1-5,7-8,10-13,18H,6,9H2
    Synonyms
    5-nitro-2-(2-phenylchroman-6-yl)oxypyridine | NCGC00485395-01 | 5-Nitro-2-[(2-phenyl-3,4-dihydro-2H-1-benzopyran-6-yl...
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Frequently Asked Questions

What can I find under Na+/Ca2+ Exchanger?
This listing collects compounds associated with Na+/Ca2+ Exchanger within our Membrane Transporter/Ion Channel area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Na+/Ca2+ Exchanger?
Consider the reported potency of each Na+/Ca2+ Exchanger compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Na+/Ca2+ Exchanger compounds?
Each Na+/Ca2+ Exchanger product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Na+/Ca2+ Exchanger compounds by activity or structure?
Yes. Filter the Na+/Ca2+ Exchanger listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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