NAMPT

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  1. STF 118804
    CAS: 894187-61-2 PubChem CID: 20916937 Formula: C25H23N3O4S Molecular Weight: 461.53
    ● In Stock — US warehouse, ships to EU* Item #: S287747
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    Technical Identifiers
    IUPAC Name
    4-[5-methyl-4-[(4-methylphenyl)sulfonylmethyl]-1,3-oxazol-2-yl]-N-(pyridin-3-ylmethyl)benzamide
    SMILES
    CC1=CC=C(C=C1)S(=O)(=O)CC2=C(OC(=N2)C3=CC=C(C=C3)C(=O)NCC4=CN=CC=C4)C
    InChIKey
    DLFCEZOMHBPDGI-UHFFFAOYSA-N
    InChI
    1S/C25H23N3O4S/c1-17-5-11-22(12-6-17)33(30,31)16-23-18(2)32-25(28-23)21-9-7-20(8-10-21)24(29)27-15-19-4-3-13-26-14-19/h3-14H,15-16H2,1-2H3,(H,27,29)
    Synonyms
    4-[5-Methyl-4-[[(4-methylphenyl)sulfonyl]methyl]-2-oxazolyl]-N-(3-pyridinylmethyl)benzamide | 4-(5-Methyl-4-(tosylmet...
  2. FK866 (APO866, Daporinad), Nicotinamide phosphoribosyltransferase inhibitor
    CAS: 658084-64-1 Formula: C24H29N3O2 Molecular Weight: 391.51
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: F127321
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    IUPAC Name
    (E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-pyridin-3-ylprop-2-enamide
    SMILES
    C1CN(CCC1CCCCNC(=O)C=CC2=CN=CC=C2)C(=O)C3=CC=CC=C3
    InChIKey
    KPBNHDGDUADAGP-VAWYXSNFSA-N
    InChI
    1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,show more
    Synonyms
    DAPORINAD [WHO-DD] | DGB | NCGC00182868-04 | GTPL7745 | 4o1b | EX-A430 | s2799 | (E)-N-[4-(1-benzoylpiperidin-4-yl)bu...
  3. GMX1778
    CAS: 200484-11-3 Formula: C19H22ClN5O Molecular Weight: 371.86
    ● In Stock — US warehouse, ships to EU* Item #: G168348
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    IUPAC Name
    2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine
    SMILES
    C1=CC(=CC=C1OCCCCCCN=C(NC#N)NC2=CC=NC=C2)Cl
    InChIKey
    BOIPLTNGIAPDBY-UHFFFAOYSA-N
    InChI
    1S/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25)
    Synonyms
    A857604 | AKOS028109359 | N0607 | AS-71873 | 1-[6-(4-Chlorophenoxy)hexyl]-3-cyano-2-pyridin-4-ylguanidine | N-CYANO-N...
  4. CB30865
    CAS: 206275-15-2 Formula: C26H22BrN5O2 Molecular Weight: 516.39
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: C125837
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    IUPAC Name
    4-[(7-bromo-2-methyl-4-oxo-3H-quinazolin-6-yl)methyl-prop-2-ynylamino]-N-(pyridin-3-ylmethyl)benzamide
    SMILES
    CC1=NC2=C(C=C(C(=C2)Br)CN(CC#C)C3=CC=C(C=C3)C(=O)NCC4=CN=CC=C4)C(=O)N1
    InChIKey
    SHNBLWMBWXIKMR-UHFFFAOYSA-N
    InChI
    1S/C26H22BrN5O2/c1-3-11-32(16-20-12-22-24(13-23(20)27)30-17(2)31-26(22)34)21-8-6-19(7-9-21)25(33)29-15-18-5-4-10-28-14-18/h1,4-10,12-14H,11,15-16H2,2Hshow more
    Synonyms
    4-(((7-bromo-2-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)(prop-2-yn-1-yl)amino)-N-(pyridin-3-ylmethyl)benzamide ...
  5. FK866 (APO866, Daporinad), Nicotinamide phosphoribosyltransferase inhibitor
    CAS: 658084-64-1 Formula: C24H29N3O2 Molecular Weight: 391.51
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: F425320
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    Technical Identifiers
    IUPAC Name
    (E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-pyridin-3-ylprop-2-enamide
    SMILES
    C1CN(CCC1CCCCNC(=O)C=CC2=CN=CC=C2)C(=O)C3=CC=CC=C3
    InChIKey
    KPBNHDGDUADAGP-VAWYXSNFSA-N
    InChI
    1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,show more
    Synonyms
    Daporinad|658084-64-1|FK866|FK-866|APO-866|APO866|201034-75-5|FK 866|Daporinad [INN]|APO 866|(E)-N-[4-(1-benzoylpiper...
  6. GMX1778
    CAS: 200484-11-3 EC Number: 803-180-6 Formula: C19H22ClN5O Molecular Weight: 371.86
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: G422439
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    Technical Identifiers
    IUPAC Name
    2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine
    SMILES
    C1=CC(=CC=C1OCCCCCCN=C(NC#N)NC2=CC=NC=C2)Cl
    InChIKey
    BOIPLTNGIAPDBY-UHFFFAOYSA-N
    InChI
    1S/C19H22ClN5O/c20-16-5-7-18(8-6-16)26-14-4-2-1-3-11-23-19(24-15-21)25-17-9-12-22-13-10-17/h5-10,12-13H,1-4,11,14H2,(H2,22,23,24,25)
    Synonyms
    A857604 | AKOS028109359 | N0607 | AS-71873 | 1-[6-(4-Chlorophenoxy)hexyl]-3-cyano-2-pyridin-4-ylguanidine | N-CYANO-N...
  7. GNE-617
    CAS: 1362154-70-8 Formula: C21H15F2N3O3S Molecular Weight: 427.42
    ● In Stock — US warehouse, ships to EU* Item #: G413558
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    Technical Identifiers
    IUPAC Name
    N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]imidazo[1,2-a]pyridine-6-carboxamide
    SMILES
    C1=CC(=CC=C1CNC(=O)C2=CN3C=CN=C3C=C2)S(=O)(=O)C4=CC(=CC(=C4)F)F
    InChIKey
    XRDVXQQZLHVEQZ-UHFFFAOYSA-N
    InChI
    1S/C21H15F2N3O3S/c22-16-9-17(23)11-19(10-16)30(28,29)18-4-1-14(2-5-18)12-25-21(27)15-3-6-20-24-7-8-26(20)13-15/h1-11,13H,12H2,(H,25,27)
    Synonyms
    Imidazo[1,​2-​a]​pyridine-​6-​carboxamide,N-​[[4-​[(3,​5-​difluorophenyl)​sulfonyl]​phenyl]​methyl]​-
  8. GNE-617
    CAS: 1362154-70-8 Formula: C21H15F2N3O3S Molecular Weight: 427.42
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: G421376
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    Technical Identifiers
    IUPAC Name
    N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]imidazo[1,2-a]pyridine-6-carboxamide
    SMILES
    C1=CC(=CC=C1CNC(=O)C2=CN3C=CN=C3C=C2)S(=O)(=O)C4=CC(=CC(=C4)F)F
    InChIKey
    XRDVXQQZLHVEQZ-UHFFFAOYSA-N
    InChI
    1S/C21H15F2N3O3S/c22-16-9-17(23)11-19(10-16)30(28,29)18-4-1-14(2-5-18)12-25-21(27)15-3-6-20-24-7-8-26(20)13-15/h1-11,13H,12H2,(H,25,27)
    Synonyms
    Imidazo[1,​2-​a]​pyridine-​6-​carboxamide,N-​[[4-​[(3,​5-​difluorophenyl)​sulfonyl]​phenyl]​methyl]​-
  9. KPT 9274 ( ATG-019)
    CAS: 1643913-93-2 Formula: C35H29F3N4O3 Molecular Weight: 610.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: K414012
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    IUPAC Name
    (E)-3-(6-aminopyridin-3-yl)-N-[[5-[4-(4,4-difluoropiperidine-1-carbonyl)phenyl]-7-(4-fluorophenyl)-1-benzofuran-2-yl]methyl]prop-2-enamide
    SMILES
    C1CN(CCC1(F)F)C(=O)C2=CC=C(C=C2)C3=CC(=C4C(=C3)C=C(O4)CNC(=O)C=CC5=CN=C(C=C5)N)C6=CC=C(C=C6)F
    InChIKey
    MRFOPLWJZULAQD-SWGQDTFXSA-N
    InChI
    1S/C35H29F3N4O3/c36-28-9-7-24(8-10-28)30-19-26(23-3-5-25(6-4-23)34(44)42-15-13-35(37,38)14-16-42)17-27-18-29(45-33(27)30)21-41-32(43)12-2-22-1-11-31(3show more
    Synonyms
    (E)-3-(6-aminopyridin-3-yl)-N-((5-(4-(4,4-difluoropiperidine-1-carbonyl)phenyl)-7-(4-fluorophenyl)benzofuran-2-yl)met...
  10. KPT 9274 ( ATG-019)
    CAS: 1643913-93-2 Formula: C35H29F3N4O3 Molecular Weight: 610.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: K422035
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    Technical Identifiers
    IUPAC Name
    (E)-3-(6-aminopyridin-3-yl)-N-[[5-[4-(4,4-difluoropiperidine-1-carbonyl)phenyl]-7-(4-fluorophenyl)-1-benzofuran-2-yl]methyl]prop-2-enamide
    SMILES
    C1CN(CCC1(F)F)C(=O)C2=CC=C(C=C2)C3=CC(=C4C(=C3)C=C(O4)CNC(=O)C=CC5=CN=C(C=C5)N)C6=CC=C(C=C6)F
    InChIKey
    MRFOPLWJZULAQD-SWGQDTFXSA-N
    InChI
    1S/C35H29F3N4O3/c36-28-9-7-24(8-10-28)30-19-26(23-3-5-25(6-4-23)34(44)42-15-13-35(37,38)14-16-42)17-27-18-29(45-33(27)30)21-41-32(43)12-2-22-1-11-31(3show more
    Synonyms
    (E)-3-(6-aminopyridin-3-yl)-N-((5-(4-(4,4-difluoropiperidine-1-carbonyl)phenyl)-7-(4-fluorophenyl)benzofuran-2-yl)met...
  11. SBI-797812
    CAS: 2237268-08-3 PubChem CID: 135222620 Formula: C19H22N4O4S Molecular Weight: 402.47
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: S422688
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    Technical Identifiers
    IUPAC Name
    1-[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)phenyl]-3-(pyridin-4-ylmethyl)urea
    SMILES
    C1CC2CN(CC1O2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)NCC4=CC=NC=C4
    InChIKey
    KTSOHNHLOLGQCY-UHFFFAOYSA-N
    InChI
    1S/C19H22N4O4S/c24-19(21-11-14-7-9-20-10-8-14)22-15-1-5-18(6-2-15)28(25,26)23-12-16-3-4-17(13-23)27-16/h1-2,5-10,16-17H,3-4,11-13H2,(H2,21,22,24)
    Synonyms
    Urea,N-​[4-​(8-​oxa-​3-​azabicyclo[3.2.1]​oct-​3-​ylsulfonyl)​phenyl]​-​N'-​(4-​pyridinylmethyl)​-
  12. SBI-797812
    CAS: 2237268-08-3 PubChem CID: 135222620 Formula: C19H22N4O4S Molecular Weight: 402.47
    ● In Stock — US warehouse, ships to EU* Item #: S414308
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    Technical Identifiers
    IUPAC Name
    1-[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)phenyl]-3-(pyridin-4-ylmethyl)urea
    SMILES
    C1CC2CN(CC1O2)S(=O)(=O)C3=CC=C(C=C3)NC(=O)NCC4=CC=NC=C4
    InChIKey
    KTSOHNHLOLGQCY-UHFFFAOYSA-N
    InChI
    1S/C19H22N4O4S/c24-19(21-11-14-7-9-20-10-8-14)22-15-1-5-18(6-2-15)28(25,26)23-12-16-3-4-17(13-23)27-16/h1-2,5-10,16-17H,3-4,11-13H2,(H2,21,22,24)
    Synonyms
    1-[4-(8-Oxa-3-azabicyclo[3.2.1]octane-3-sulfonyl)-phenyl]-3-pyridin-4-ylmethylurea | N-[4-(8-Oxa-3-azabicyclo[3.2.1]o...
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Frequently Asked Questions

Which compounds are listed for NAMPT?
Compounds associated with NAMPT are grouped here under the Metabolic Enzyme/Protease classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does NAMPT sit within Metabolic Enzyme/Protease?
NAMPT is one target listing within the Metabolic Enzyme/Protease classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from NAMPT?
For compounds listed under NAMPT, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for NAMPT?
Browse the parent Metabolic Enzyme/Protease listing to reach targets neighbouring NAMPT, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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