Opioid Receptor

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  1. GR 89696 fumarate
    CAS: 126766-32-3 PubChem CID: 6442840 Formula: C19H25Cl2N3O3•C4H4O4 Molecular Weight: 530.4
    ● In Stock — US warehouse, ships to EU* Item #: G286626
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    IUPAC Name
    (E)-but-2-enedioic acid;methyl 4-[2-(3,4-dichlorophenyl)acetyl]-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate
    SMILES
    COC(=O)N1CCN(C(C1)CN2CCCC2)C(=O)CC3=CC(=C(C=C3)Cl)Cl.C(=CC(=O)O)C(=O)O
    InChIKey
    ABTNETSDXZBJTE-WLHGVMLRSA-N
    InChI
    1S/C19H25Cl2N3O3.C4H4O4/c1-27-19(26)23-8-9-24(15(13-23)12-22-6-2-3-7-22)18(25)11-14-4-5-16(20)17(21)10-14;5-3(6)1-2-4(7)8/h4-5,10,15H,2-3,6-9,11-13H2,show more
    Synonyms
    (E)-but-2-enedioic acid;methyl 4-[2-(3,4-dichlorophenyl)acetyl]-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate | (...
  2. Naloxone HCl, Opioid receptors; mu/kappa/delta antagonist
    CAS: 357-08-4 EC Number: 206-611-0 Formula: C19H21NO4·HCl Molecular Weight: 363.84
    ● In Stock — US warehouse, ships to EU* Item #: N129470
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    IUPAC Name
    (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride
    SMILES
    C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl
    InChIKey
    RGPDIGOSVORSAK-STHHAXOLSA-N
    InChI
    1S/C19H21NO4.ClH/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;/h2-4,14,17,21,23H,1,5-10H2;1H/t14-,17+,18+,19-;/m1./sshow more
    Synonyms
    4(5)-imidazolecarboxylic acid | 6-methoxy-tetralone | CHEBI:31892 | Morphinan-6-one, 17-allyl-4,5-alpha-epoxy-3,14-di...
  3. GNTI dihydrochloride
    CAS: 351183-88-5 PubChem CID: 90479777 Formula: C₂₇H₂₉N₅O₃•₂HCl Molecular Weight: 544.48
    ◐ .Made to order · 8–12 wks Item #: G287224
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    OC3=CC=C2CC([C@@]5(O)[C@@]4(CC8)C2=C3O[C@H]4C(NC7=C6C=C(NC=N)C=C7)=C6C5)N8CC1CC1.Cl.Cl
    InChIKey
    GJPIMNXJPMPQHK-CVVXFVLRSA-N
    Synonyms
    5'-Guanidinyl-17-(cyclopropylmethyl)-6,7-dehydro-4,5α-epoxy-3,14-dihydroxy-6,7-2',3'-indolomorphinan dihydrochloride
  4. Bisacodyl
    CAS: 603-50-9 EC Number: 210-044-4 Formula: C22H19NO4 Molecular Weight: 361.39
    ● In Stock — US warehouse, ships to EU* Item #: B129453
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    IUPAC Name
    [4-[(4-acetyloxyphenyl)-pyridin-2-ylmethyl]phenyl] acetate
    SMILES
    CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3
    InChIKey
    KHOITXIGCFIULA-UHFFFAOYSA-N
    InChI
    1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3
    Synonyms
    LACO | Neolax | UNII-10X0709Y6I | Womans Laxative | CCRIS 8864 | SMR000058226 | Stadalax | Bisacodyl Laxative | Defic...
  5. N-desmethylclozapine, Allosteric modulator of M 1 receptor
    CAS: 6104-71-8 EC Number: 636-421-7 Formula: C17H17ClN4 Molecular Weight: 312.8
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: N298816
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    IUPAC Name
    3-chloro-6-piperazin-1-yl-11H-benzo[b][1,4]benzodiazepine
    SMILES
    C1CN(CCN1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42
    InChIKey
    JNNOSTQEZICQQP-UHFFFAOYSA-N
    InChI
    1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19-20H,7-10H2
    Synonyms
    BCP30683 | CAS_2820 | GTPL333 | UNII-1I9001LWY8 | BDBM50122054 | BRD-K10042277-001-04-3 | Desmethylclozapine | 3-chlo...
  6. [Arg14,Lys15]Nociceptin
    CAS: 236098-40-1 Formula: C82H137N31O22 Molecular Weight: 1909.18
    ◐ .Made to order · 8–12 wks Item #: A287678
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    IUPAC Name
    (2S)-5-amino-2-[[(2S)-4-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,3R)show more
    SMILES
    CC(C(C(=O)NCC(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(show more
    InChIKey
    VULLMZOQBGUKAT-VUXBHJHDSA-N
    InChI
    1S/C82H137N31O22/c1-44(101-63(119)42-100-78(133)65(46(3)115)113-76(131)57(38-48-21-8-5-9-22-48)103-64(120)41-98-62(118)40-99-68(123)49(86)37-47-19-6-4show more
  7. Deltorphin 2 TFA, Agonist of δ receptor
    CAS: 122752-16-3(free basis) Formula: C38H54N8O10(free basis) Molecular Weight: 782.89(free basis)
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: D275239
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    Synonyms
    [D-Ala2]-Deltorphin II TFA
  8. Loperamide Oxide
    CAS: 106900-12-3 Formula: C29H33ClN2O3 Molecular Weight: 493.04
    ◐ .Made to order · 8–12 wks Item #: L356038
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    IUPAC Name
    4-[4-(4-chlorophenyl)-4-hydroxy-1-oxidopiperidin-1-ium-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
    SMILES
    CN(C)C(=O)C(CC[N+]1(CCC(CC1)(C2=CC=C(C=C2)Cl)O)[O-])(C3=CC=CC=C3)C4=CC=CC=C4
    InChIKey
    KXVSBTJVTUVNPM-UHFFFAOYSA-N
    InChI
    1S/C29H33ClN2O3/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32(35)20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3
    Synonyms
    1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, 1-oxide, cis- | TRANS-4-(P-C...
  9. Loperamide HCl, Mu opioid receptor agonist
    CAS: 34552-83-5 EC Number: 252-082-4 Formula: C29H33ClN2O2·HCl Molecular Weight: 513.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: L129465
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    IUPAC Name
    4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride
    SMILES
    CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl
    InChIKey
    PGYPOBZJRVSMDS-UHFFFAOYSA-N
    InChI
    1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3show more
    Synonyms
    Norepinephrine hydrochloride | SPECTRUM2300241 | Cardiazole | gamma-Picolinic acid | MFCD00058581 | Stomach Relief An...
  10. Nociceptin (Orphanin FQ), Agonist of NOP receptor
    CAS: 170713-75-4 PubChem CID: 16131448 Formula: C79H129N27O22 Molecular Weight: 1809.06
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: N274936
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    Technical Identifiers
    IUPAC Name
    (2S)-5-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,3R)-2-[[(2Sshow more
    SMILES
    CC(C)CC(C(=O)NC(C)C(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=Oshow more
    InChIKey
    PULGYDLMFSFVBL-SMFNREODSA-N
    InChI
    1S/C79H129N27O22/c1-41(2)33-54(72(122)95-44(5)66(116)103-56(36-59(84)110)73(123)102-53(77(127)128)27-28-58(83)109)104-70(120)49(23-13-15-29-80)100-69(show more
    Synonyms
    PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-UNK-ALA-ARG-LYS-LEU-ALA-ASN-GLN | SCHEMBL316725 | Human nociceptin | L-Phe-Gl...
  11. SCH 221510, Agonist of δ receptor;Agonist of κ receptor;Agonist of μ receptor;Agonist of NOP receptor
    CAS: 322473-89-2 PubChem CID: 9887077 Formula: C28H31NO Molecular Weight: 397.55
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S287959
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    IUPAC Name
    8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol
    SMILES
    CC1=CC=CC=C1C(C2=CC=CC=C2C)N3C4CCC3CC(C4)(C5=CC=CC=C5)O
    InChIKey
    LOSJNRBXNQTUNT-UHFFFAOYSA-N
    InChI
    1S/C28H31NO/c1-20-10-6-8-14-25(20)27(26-15-9-7-11-21(26)2)29-23-16-17-24(29)19-28(30,18-23)22-12-4-3-5-13-22/h3-15,23-24,27,30H,16-19H2,1-2H3
    Synonyms
    8-(dio-tolylmethyl)-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol | GTPL8868 | AKOS024457501 | 8-[bis(2-methylphenyl)methyl]...
  12. SNC 162
    CAS: 178803-51-5 PubChem CID: 6604878 Formula: C27H37N3O Molecular Weight: 419.61
    ◐ .Made to order · 8–12 wks Item #: S286825
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    IUPAC Name
    4-[(S)-[(2S,5R)-2,5-dimethyl-4-prop-2-enylpiperazin-1-yl]-phenylmethyl]-N,N-diethylbenzamide
    SMILES
    CCN(CC)C(=O)C1=CC=C(C=C1)C(C2=CC=CC=C2)N3CC(N(CC3C)CC=C)C
    InChIKey
    WGIDFDFAOQVAHY-UFPGJGBJSA-N
    InChI
    1S/C27H37N3O/c1-6-18-29-19-22(5)30(20-21(29)4)26(23-12-10-9-11-13-23)24-14-16-25(17-15-24)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,show more
    Synonyms
    4-[(S)-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]phenylmethyl]-N,N-diethylbenzamide
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Frequently Asked Questions

How is the Opioid Receptor listing put together?
It draws on reported Opioid Receptor annotations within GPCR/G Protein and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an Opioid Receptor modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Opioid Receptor entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Opioid Receptor compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Opioid Receptor work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Opioid Receptor compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Opioid Receptor compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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