PD-1/PD-L1

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  1. PD-1/PD-L1 inhibitor 1
    CAS: 1675201-83-8 PubChem CID: 91663303 Formula: C29H33NO5 Molecular Weight: 475.6
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P276510
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    IUPAC Name
    (2S)-1-[[2,6-dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylic acid
    SMILES
    CC1=C(C=CC=C1C2=CC=CC=C2)COC3=CC(=C(C(=C3)OC)CN4CCCCC4C(=O)O)OC
    InChIKey
    ZBOYJODMIAUJHH-SANMLTNESA-N
    InChI
    1S/C29H33NO5/c1-20-22(12-9-13-24(20)21-10-5-4-6-11-21)19-35-23-16-27(33-2)25(28(17-23)34-3)18-30-15-8-7-14-26(30)29(31)32/h4-6,9-13,16-17,26H,7-8,14-1show more
    Synonyms
    (2S)-1-[[2,6-dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylicacid | (S)-1-(2,6-dim...
  2. Acesulfame K
    CAS: 55589-62-3 EC Number: 259-715-3 Formula: C4H4KNO4S Molecular Weight: 201.24
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — Germany Item #: A113942
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    IUPAC Name
    potassium;6-methyl-2,2-dioxo-1-oxa-2λ6-thia-3-azanidacyclohex-5-en-4-one
    SMILES
    CC1=CC(=O)[N-]S(=O)(=O)O1.[K+]
    InChIKey
    WBZFUFAFFUEMEI-UHFFFAOYSA-M
    InChI
    1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1
    Synonyms
    4-(1H-Tetrazol-1-yl)benzoic acid, AldrichCPR | INS-950 | 1-Phenyl-3-(pyridin-3-yl)urea | Acesulfame potassium, Europe...
  3. BMS202 (PD-1/PD-L1 inhibitor 2), Agonist of CB 1 receptor;Agonist of CB 2 receptor
    CAS: 1675203-84-5 Formula: C25H29N3O3 Molecular Weight: 419.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: B276435
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    IUPAC Name
    N-[2-[[2-methoxy-6-[(2-methyl-3-phenylphenyl)methoxy]pyridin-3-yl]methylamino]ethyl]acetamide
    SMILES
    CC1=C(C=CC=C1C2=CC=CC=C2)COC3=NC(=C(C=C3)CNCCNC(=O)C)OC
    InChIKey
    JEDPSOYOYVELLZ-UHFFFAOYSA-N
    InChI
    1S/C25H29N3O3/c1-18-22(10-7-11-23(18)20-8-5-4-6-9-20)17-31-24-13-12-21(25(28-24)30-3)16-26-14-15-27-19(2)29/h4-13,26H,14-17H2,1-3H3,(H,27,29)
    Synonyms
    N-[2-[[[2-Methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]-3-pyridinyl]methyl]amino]ethyl]acetamide;PD1-PDL1 inhibit...
  4. Sulfamethoxypyridazine, Bacterial dihydropteroate synthase inhibitor
    CAS: 80-35-3 PubChem CID: 5330 Formula: C11H12N4O3S Molecular Weight: 280.3
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: S114298
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    IUPAC Name
    4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide
    SMILES
    COC1=NN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N
    InChIKey
    VLYWMPOKSSWJAL-UHFFFAOYSA-N
    InChI
    1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)
    Synonyms
    KBio2_006767 | Lentac | Slosul | Altezol | DTXSID5023611 | Opera_ID_698 | SPBio_002587 | Sulfamethoxypyridazinum | Di...
  5. Sulindac, Cyclooxygenase inhibitor
    CAS: 38194-50-2 EC Number: 250-893-8, 232-527-9, 253-819-2 PubChem CID: 1548887 Formula: C20H17FO3S Molecular Weight: 356.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S125148
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    IUPAC Name
    2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid
    SMILES
    CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O
    InChIKey
    MLKXDPUZXIRXEP-MFOYZWKCSA-N
    InChI
    1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-
    Synonyms
    1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)- | Aflodac | SULINDAC (USP M...
  6. (+)-JQ1 carboxylic acid
    CAS: 202592-23-2 Formula: C19H17ClN4O2S Molecular Weight: 400.88
    ● In Stock — US warehouse, ships to EU* Item #: J286888
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    IUPAC Name
    2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetic acid
    SMILES
    CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)O)C4=CC=C(C=C4)Cl)C
    InChIKey
    LJOSBOOJFIRCSO-AWEZNQCLSA-N
    InChI
    1S/C19H17ClN4O2S/c1-9-10(2)27-19-16(9)17(12-4-6-13(20)7-5-12)21-14(8-15(25)26)18-23-22-11(3)24(18)19/h4-7,14H,8H2,1-3H3,(H,25,26)/t14-/m0/s1
    Synonyms
    EX-A1891 | MFCD28167916 | BCP20870 | 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorop...
  7. Panaxadiol
    CAS: 19666-76-3 Formula: C30H52O3 Molecular Weight: 460.7
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: P110219
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    IUPAC Name
    (3S,5R,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-2,6,6-trimethyloxan-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[ashow more
    SMILES
    CC1(CCCC(O1)(C)C2CCC3(C2C(CC4C3(CCC5C4(CCC(C5(C)C)O)C)C)O)C)C
    InChIKey
    PVLHOJXLNBFHDX-XHJPDDKBSA-N
    InChI
    1S/C30H52O3/c1-25(2)13-9-14-30(8,33-25)19-10-16-29(7)24(19)20(31)18-22-27(5)15-12-23(32)26(3,4)21(27)11-17-28(22,29)6/h19-24,31-32H,9-18H2,1-8H3/t19-,show more
    Synonyms
    20(R)-Panaxadiol | (3S,5R,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-2,6,6-trimethyloxan-2-yl]-2,3,5...
  8. Fraxinellone
    CAS: 28808-62-0 EC Number: 683-158-9 Formula: C14H16O3 Molecular Weight: 232.28
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: F405738
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    IUPAC Name
    (3R,3aR)-3-(furan-3-yl)-3a,7-dimethyl-3,4,5,6-tetrahydro-2-benzofuran-1-one
    SMILES
    CC1=C2C(=O)OC(C2(CCC1)C)C3=COC=C3
    InChIKey
    XYYAFLHHHZVPRN-GXTWGEPZSA-N
    InChI
    1S/C14H16O3/c1-9-4-3-6-14(2)11(9)13(15)17-12(14)10-5-7-16-8-10/h5,7-8,12H,3-4,6H2,1-2H3/t12-,14+/m0/s1
    Synonyms
    (3R,3aR)-3-(uran-3-yl)-3a,7-dimethyl-3,4,5,6-tetrahydro-2-benzouran-1-one | F1187 | NCI60_012928 | 4-(m-chlorophenyl)...
  9. (D)-PPA 1
    CAS: 1620813-53-7 PubChem CID: 134160249 Formula: C70H98N20O21 Molecular Weight: 1555.67
    ◐ .Made to order · 8–12 wks Item #: D287924
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    IUPAC Name
    (3R)-4-[[(2R)-1-[[(2R)-5-amino-1-[[(2R)-1-[[(2R)-1-[[(1R)-1-carboxy-2-phenylethyl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenshow more
    SMILES
    CC(C(C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CC2=CNC=N2)C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C4CCCN4C(=O)C(CCshow more
    InChIKey
    ZEZZLZKHZPMELC-SDQLLZIZSA-N
    InChI
    1S/C70H98N20O21/c1-36(92)57(89-66(107)53-13-8-26-90(53)68(109)46(11-5-6-24-71)82-65(106)52(34-91)88-62(103)47(27-38-14-18-41(93)19-15-38)83-58(99)43(7show more
  10. (+)-JQ1 carboxylic acid
    CAS: 202592-23-2 EC Number: 874-556-5 Formula: C19H17ClN4O2S Molecular Weight: 400.88
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: J422464
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    IUPAC Name
    2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetic acid
    SMILES
    CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)O)C4=CC=C(C=C4)Cl)C
    InChIKey
    LJOSBOOJFIRCSO-AWEZNQCLSA-N
    InChI
    1S/C19H17ClN4O2S/c1-9-10(2)27-19-16(9)17(12-4-6-13(20)7-5-12)21-14(8-15(25)26)18-23-22-11(3)24(18)19/h4-7,14H,8H2,1-3H3,(H,25,26)/t14-/m0/s1
    Synonyms
    EX-A1891 | MFCD28167916 | BCP20870 | 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorop...
  11. AUNP-12
    CAS: 1353563-85-5 PubChem CID: 154701623 Formula: C142H226N40O48 C2HF3O2 Molecular Weight: 3375.57
    10mM in Water
    ◐ .Made to order · 8–12 wks Item #: A421343
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    IUPAC Name
    (4S)-5-amino-4-[[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S,3R)-2-[[(2S)-2show more
    SMILES
    CCC(C)C(C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C1CCCN1C(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)C(Cshow more
    InChIKey
    ZBJUUYIGBAQYBN-QKLNNLIKSA-N
    InChI
    1S/C142H226N40O48/c1-12-70(6)109(137(226)165-84(37-23-26-52-144)119(208)158-81(113(151)202)43-48-105(196)197)178-125(214)87(42-47-102(148)193)159-114(show more
    Synonyms
    AUNP-12|1353563-85-5|CHEMBL4635204|EX-A7438
  12. Acesulfame K
    CAS: 55589-62-3 EC Number: 259-715-3 Formula: C4H4KNO4S Molecular Weight: 201.24
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: A113941
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    Technical Identifiers
    IUPAC Name
    potassium;6-methyl-2,2-dioxo-1-oxa-2λ6-thia-3-azanidacyclohex-5-en-4-one
    SMILES
    CC1=CC(=O)[N-]S(=O)(=O)O1.[K+]
    InChIKey
    WBZFUFAFFUEMEI-UHFFFAOYSA-M
    InChI
    1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1
    Synonyms
    4-(1H-Tetrazol-1-yl)benzoic acid, AldrichCPR | INS-950 | 1-Phenyl-3-(pyridin-3-yl)urea | Acesulfame potassium, Europe...
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Frequently Asked Questions

What can I find under PD-1/PD-L1?
This listing collects compounds associated with PD-1/PD-L1 within our Immunology/Inflammation area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for PD-1/PD-L1?
Consider the reported potency of each PD-1/PD-L1 compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for PD-1/PD-L1 compounds?
Each PD-1/PD-L1 product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search PD-1/PD-L1 compounds by activity or structure?
Yes. Filter the PD-1/PD-L1 listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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