Piezo Channel

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  1. Yoda 1, Activator of Piezo1
    CAS: 448947-81-7 EC Number: 998-870-8 PubChem CID: 2746822 Formula: C13H8Cl2N4S2 Molecular Weight: 355.27
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: Y287590
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    IUPAC Name
    2-[(2,6-dichlorophenyl)methylsulfanyl]-5-pyrazin-2-yl-1,3,4-thiadiazole
    SMILES
    C1=CC(=C(C(=C1)Cl)CSC2=NN=C(S2)C3=NC=CN=C3)Cl
    InChIKey
    BQNXBSYSQXSXPT-UHFFFAOYSA-N
    InChI
    1S/C13H8Cl2N4S2/c14-9-2-1-3-10(15)8(9)7-20-13-19-18-12(21-13)11-6-16-4-5-17-11/h1-6H,7H2
    Synonyms
    GTPL9817 | s6678 | UNII-TW6GF9RW6S | 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine | 2-[5-[[...
  2. Dooku 1, Inhibitor of Piezo1
    CAS: 2253744-54-4 Formula: C13H9Cl2N3OS Molecular Weight: 326.2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: D286644
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    IUPAC Name
    2-[(2,6-dichlorophenyl)methylsulfanyl]-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole
    SMILES
    C1=CC(=C(C(=C1)Cl)CSC2=NN=C(O2)C3=CC=CN3)Cl
    InChIKey
    MNPOBXLPCWFONX-UHFFFAOYSA-N
    InChI
    1S/C13H9Cl2N3OS/c14-9-3-1-4-10(15)8(9)7-20-13-18-17-12(19-13)11-5-2-6-16-11/h1-6,16H,7H2
    Synonyms
    2-[(2,6-Dichlorobenzyl)thio)-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole | Dooku1 | 2-((2,6-dichlorobenzyl)thio)-5-(1H-pyrrol...
  3. Jedi2, Activator of Piezo1
    CAS: 651005-90-2 Formula: C10H8O3S Molecular Weight: 208.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: J288068
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    IUPAC Name
    2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid
    SMILES
    CC1=C(C=C(O1)C2=CC=CS2)C(=O)O
    InChIKey
    YXDCRSXNEOKXDE-UHFFFAOYSA-N
    InChI
    1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12)
    Synonyms
    2-Methyl-5-(thien-2-yl)-3-furoic acid | HMS1431A19 | GLXC-25617 | 3-Furancarboxylic acid, 2-methyl-5-(2-thienyl)- | E...
  4. Dooku 1, Inhibitor of Piezo1
    CAS: 2253744-54-4 Formula: C13H9Cl2N3OS Molecular Weight: 326.2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: D422708
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    Technical Identifiers
    IUPAC Name
    2-[(2,6-dichlorophenyl)methylsulfanyl]-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole
    SMILES
    C1=CC(=C(C(=C1)Cl)CSC2=NN=C(O2)C3=CC=CN3)Cl
    InChIKey
    MNPOBXLPCWFONX-UHFFFAOYSA-N
    InChI
    1S/C13H9Cl2N3OS/c14-9-3-1-4-10(15)8(9)7-20-13-18-17-12(19-13)11-5-2-6-16-11/h1-6,16H,7H2
    Synonyms
    2-[(2,6-Dichlorobenzyl)thio)-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole | Dooku1 | 2-((2,6-dichlorobenzyl)thio)-5-(1H-pyrrol...
  5. Yoda 1, Activator of Piezo1
    CAS: 448947-81-7 EC Number: 998-870-8 PubChem CID: 2746822 Formula: C13H8Cl2N4S2 Molecular Weight: 355.27
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: Y424043
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-[(2,6-dichlorophenyl)methylsulfanyl]-5-pyrazin-2-yl-1,3,4-thiadiazole
    SMILES
    C1=CC(=C(C(=C1)Cl)CSC2=NN=C(S2)C3=NC=CN=C3)Cl
    InChIKey
    BQNXBSYSQXSXPT-UHFFFAOYSA-N
    InChI
    1S/C13H8Cl2N4S2/c14-9-2-1-3-10(15)8(9)7-20-13-19-18-12(21-13)11-6-16-4-5-17-11/h1-6H,7H2
    Synonyms
    GTPL9817 | s6678 | UNII-TW6GF9RW6S | 2-[5-[[(2,6-Dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]pyrazine | 2-[5-[[...
  6. Jedi2
    CAS: 651005-90-2 Formula: C10H8O3S Molecular Weight: 208.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: J1496071
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under Piezo Channel?
This listing collects compounds associated with Piezo Channel within our Membrane Transporter/Ion Channel area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Piezo Channel?
Consider the reported potency of each Piezo Channel compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Piezo Channel compounds?
Each Piezo Channel product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Piezo Channel compounds by activity or structure?
Yes. Filter the Piezo Channel listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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