TGF-beta/Smad - PKA Supplier | High Purity

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N⁶,2′-O-Dibutyryladenosine 3′,5′ -cyclic monophosphate sodium salt
CAS: 16980-89-5 EC Number: 241-059-4 Formula: C₁₈H₂₃N₅O₈PNa Molecular Weight: 491.37

≥97%(HPLC)

● In Stock — US warehouse, ships to EU* Item #: D124575
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IUPAC Name

sodium;[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate

SMILES

CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C4C(O3)COP(=O)(O4)[O-])OC(=O)CCC.[Na+]

InChIKey
KRBZRVBLIUDQNG-JBVYASIDSA-M

InChI

1S/C18H24N5O8P.Na/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14;/h8-10,14-15,18H,3-7H2,1-2H3,(H,show more

Synonyms
Dibutyryl cAMP (sodium salt);DBcAMP (sodium salt) | InChI=1/C6H10O2/c7-6-4-2-1-3-5-8-6/h1-5H | Actosin | Adenosine, N...
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Taurodeoxychloic acid
CAS: 516-50-7 Formula: C₂₆H₄₅NO₆S Molecular Weight: 499.70

Solid ≥98%

◐ .Made to order · 8–12 wks Item #: T336191
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IUPAC Name

2-[[(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrshow more

SMILES

CC(CCC(=O)NCCS(=O)(=O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C

InChIKey
AWDRATDZQPNJFN-VAYUFCLWSA-N

InChI

1S/C26H45NO6S/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3/h16-23,28-29H,4-15H2,1-3H3,(H,show more

Synonyms
2-[4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydr...
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PKI 14-22 amide,myristoylated TFA, Inhibitor of protein kinase A
CAS: 201422-03-9 PubChem CID: 71312213 Formula: C₅₃H₁₀₀N₂₀O₁₂(free) Molecular Weight: 1209.49(free)

Moligand™ ? ≥98%

● In Stock — US warehouse, ships to EU* Item #: P287239
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IUPAC Name

(2S)-N-[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-(diaminomethylidenshow more

SMILES

CCCCCCCCCCCCCC(=O)NCC(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC(=O)N)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)N

InChIKey
GQPQKQWUUHDDIS-JDLJUXOTSA-N

InChI

1S/C53H100N20O12/c1-6-8-9-10-11-12-13-14-15-16-17-24-39(76)65-29-40(77)69-35(22-19-26-63-52(58)59)48(83)73-43(33(5)74)50(85)66-30-41(78)68-34(21-18-25show more

Synonyms
Protein kinase inhibitor-(14-22)-amide, myristoylated
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cAMPS-Rp, triethylammonium salt
CAS: 151837-09-1 Formula: C₁₀H₁₂N₅O₅PS.C₆H₁₅N Molecular Weight: 446.46

≥98%(HPLC)

◐ .Made to order · 8–12 wks Item #: C286882
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IUPAC Name

(4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-hydroxy-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol;N,N-diethylethanamine

SMILES

CCN(CC)CC.C1C2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)OP(=S)(O1)O

InChIKey
OXIPZMKSNMRTIV-NVGWRVNNSA-N

InChI

1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6show more

Synonyms
(R)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium
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cAMPS-Sp, triethylammonium salt
CAS: 93602-66-5 Formula: C₁₀H₁₂N₅O₅PS.C₆H₁₅N Molecular Weight: 446.46

≥98%(HPLC)

◐ .Made to order · 8–12 wks Item #: C288425
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IUPAC Name

6-(6-aminopurin-9-yl)-2-hydroxy-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol;N,N-diethylethanamine

SMILES

CCN(CC)CC.C1C2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)OP(=S)(O1)O

InChIKey
OXIPZMKSNMRTIV-UHFFFAOYSA-N

InChI

1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6show more

Synonyms
cAMPS-Sp, triethylammonium salt | 6-(6-aminopurin-9-yl)-2-hydroxy-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d]...
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TX-1123
CAS: 157397-06-3 PubChem CID: 403661 Formula: C₂₀H₂₄O₃ Molecular Weight: 312.4

◐ .Made to order · 8–12 wks Item #: T339226
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IUPAC Name

2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]cyclopent-4-ene-1,3-dione

SMILES

CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C2C(=O)C=CC2=O

InChIKey
VUEUMQIBGLKJJD-UHFFFAOYSA-N

InChI

1S/C20H24O3/c1-19(2,3)14-10-12(9-13-16(21)7-8-17(13)22)11-15(18(14)23)20(4,5)6/h7-11,23H,1-6H3

Synonyms
2-((3,5-di-tert-Butyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione
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D-Mannitol
CAS: 69-65-8 EC Number: 200-711-8 Formula: C₆H₁₄O₆ Molecular Weight: 182.17

Solid Suitable for plant cell culture ? ≥99%

● In Stock — US warehouse, ships to EU* Item #: M119324
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IUPAC Name

(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol

SMILES

C(C(C(C(C(CO)O)O)O)O)O

InChIKey
FBPFZTCFMRRESA-KVTDHHQDSA-N

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1

Synonyms
D-mitobronitol | Mannitol [USAN] | Mannitol, D- | Osmitrol 10% In Water | DL-Mannitol | Mannistol | Osmofundin | D-(-...
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H8 dihydrochloride
CAS: 113276-94-1 PubChem CID: 150584 Formula: C₁₂H₁₇Cl₂N₃O₂S Molecular Weight: 338.25

≥98%

● In Stock — US warehouse, ships to EU* Item #: H276181
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IUPAC Name

N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide;dihydrochloride

SMILES

CNCCNS(=O)(=O)C1=CC=CC2=C1C=CN=C2.Cl.Cl

InChIKey
RJJLZYZEVNCZIW-UHFFFAOYSA-N

InChI

1S/C12H15N3O2S.2ClH/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12;;/h2-6,9,13,15H,7-8H2,1H3;2*1H

Synonyms
AKOS015919086 | 5-Isoquinolinesulfonamide,N-[2-(methylamino)ethyl]-,hydrochloride(1:2) | Allene (ca. 2% in N,N-Dimeth...
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5-(Piperazin-1-ylsulfonyl)isoquinoline
CAS: 84468-24-6 EC Number: 635-920-7 Formula: C₁₃H₁₅N₃O₂S Molecular Weight: 277.34

≥98%

● In Stock — US warehouse, ships to EU* Item #: H275141
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IUPAC Name

5-piperazin-1-ylsulfonylisoquinoline

SMILES

C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3

InChIKey
UPTYCYWTFGTCCG-UHFFFAOYSA-N

InChI

1S/C13H15N3O2S/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13/h1-5,10,14H,6-9H2

Synonyms
1-(5-Isoquinolinesulfonyl)piperazine | Piperazine, 1-(5-isoquinolinylsulfonyl)- | BDBM15203 | MFCD00209852 | NCGC0002...
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HA-1004
CAS: 91742-10-8 Formula: C₁₂H₁₅N₅O₂S Molecular Weight: 293.35

Moligand™ ? ≥97%

◐ .Made to order · 8–12 wks Item #: H331174
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IUPAC Name

2-[2-(isoquinolin-5-ylsulfonylamino)ethyl]guanidine

SMILES

C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN=C(N)N

InChIKey
MZNDNBFMSVMUCX-UHFFFAOYSA-N

InChI

1S/C12H15N5O2S/c13-12(14)16-6-7-17-20(18,19)11-3-1-2-9-8-15-5-4-10(9)11/h1-5,8,17H,6-7H2,(H4,13,14,16)

Synonyms
HA 1004 | HA1004 | ha-1004 | N-(2-((Aminoiminomethyl)amino)ethyl)-5-isoquinolinesulfonamide | HT 1004 | KBio2_005589 ...
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Isovaleric acid
CAS: 503-74-2 EC Number: 207-975-3 Formula: C₅H₁₀O₂ Molecular Weight: 102.13

≥99%

● In Stock — Germany Item #: I108281
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IUPAC Name

3-methylbutanoic acid

SMILES

CC(C)CC(=O)O

InChIKey
GWYFCOCPABKNJV-UHFFFAOYSA-N

InChI

1S/C5H10O2/c1-4(2)3-5(6)7/h4H,3H2,1-2H3,(H,6,7)

Synonyms
ISOVALERIC ACID (MART.) | Isobutyl formic acid | 3,4-Diisovaleryl adrenaline | BCP32116 | b-Methylbutyric acid | CAS-...
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K-252a
CAS: 99533-80-9 EC Number: 640-127-4 Formula: C₂₇H₂₁N₃O₅ Molecular Weight: 467.47

Solid ≥97%(HPLC)

◐ .Made to order · 8–12 wks Item #: K139531
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IUPAC Name

methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,2show more

SMILES

CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)OC)O

InChIKey
KOZFSFOOLUUIGY-SOLYNIJKSA-N

InChI

1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11show more

Synonyms
K 252 | methyl (5S,6R,8R)-6-hydroxy-5-methyl-13-oxo-5,6,7,8,14,15-hexahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]...

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Frequently Asked Questions

What can I find under PKA?

This listing collects compounds associated with PKA within our TGF-beta/Smad area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.

What should I consider when picking a compound for PKA?

Consider the reported potency of each PKA compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.

What quality information is provided for PKA compounds?

Each PKA product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

Can I search PKA compounds by activity or structure?

Yes. Filter the PKA listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].