Polo-like Kinase (PLK)
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86 products
Popular Products
- GSK461364, Serine/threonine-protein kinase PLK1 inhibitorCAS: 929095-18-1 Formula: C27H28F3N5O2S Molecular Weight: 543.62Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G127124View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-[6-[(4-methylpiperazin-1-yl)methyl]benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxamide
- SMILES
- CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N
- InChIKey
- ZHJGWYRLJUCMRT-QGZVFWFLSA-N
- InChI
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- Synonyms
- CCG-264940 | GTPL5684 | SW220052-1 | AC-23167 | GSK 461364 | 5-[6-[(4-Methyl-1-piperazinyl)methyl]-1h-benzimidazol-1-...
- Ro3280, Inhibitor of FER tyrosine kinase;Inhibitor of polo like kinase 1;Inhibitor of TTK protein kinaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: R127227View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-8H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
- SMILES
- CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC
- InChIKey
- DJNZZLZKAXGMMC-UHFFFAOYSA-N
- InChI
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- Synonyms
- BCP05205 | HMS3653O21 | PharmaGSID_48511 | 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid | 4-((9-Cyclope...
- ON-01910CAS: 1225497-78-8 Formula: C21H24NO8S・Na Molecular Weight: 473.43● In Stock — US warehouse, ships to EU* Item #: O335808View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- sodium;2-[2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]anilino]acetate
- SMILES
- COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)NCC(=O)[O-].[Na+]
- InChIKey
- VLQLUZFVFXYXQE-USRGLUTNSA-M
- InChI
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- Synonyms
- ON-01910Na | ON-019190 (sodium) | rigosertib sodium salt | ON 01910.Na | SODIUM 2-[(2-METHOXY-5-{[2-(2,4,6-TRIMETHOXY...
- MLN0905, Inhibitor of polo like kinase 1CAS: 1228960-69-7 Formula: C24H25F3N6S Molecular Weight: 486.56Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: M126487View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[[5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl]amino]-9-(trifluoromethyl)-5,7-dihydropyrimido[5,4-d][1]benzazepine-6-thione
- SMILES
- CC1=C(C=C(C=N1)CCCN(C)C)NC2=NC=C3CC(=S)NC4=C(C3=N2)C=CC(=C4)C(F)(F)F
- InChIKey
- CODBZFJPKJDNDT-UHFFFAOYSA-N
- InChI
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- Synonyms
- 2-(5-(3-(DIMETHYLAMINO)PROPYL)-2-METHYLPYRIDIN-3-YLAMINO)-9-(TRIFLUOROMETHYL)-5H-BENZO[B]PYRIMIDO[4,5-D]AZEPINE-6(7H)...
- BI 2536, Serine/threonine-protein kinase PLK1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: B129994View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
- SMILES
- CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
- InChIKey
- XQVVPGYIWAGRNI-JOCHJYFZSA-N
- InChI
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- Synonyms
- (R)-4-(8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylamino)-3-methoxy-N-(1-methylpiperidin-4-yl...
- HMN-214CAS: 173529-46-9 Formula: C22H20N2O5S Molecular Weight: 424.48● In Stock — US warehouse, ships to EU* Item #: H125770View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(4-methoxyphenyl)sulfonyl-N-[2-[(E)-2-(1-oxidopyridin-1-ium-4-yl)ethenyl]phenyl]acetamide
- SMILES
- CC(=O)N(C1=CC=CC=C1C=CC2=CC=[N+](C=C2)[O-])S(=O)(=O)C3=CC=C(C=C3)OC
- InChIKey
- OCKHRKSTDPOHEN-BQYQJAHWSA-N
- InChI
- 1S/C22H20N2O5S/c1-17(25)24(30(27,28)21-11-9-20(29-2)10-12-21)22-6-4-3-5-19(22)8-7-18-13-15-23(26)16-14-18/h3-16H,1-2H3/b8-7+
- Synonyms
- BRD-K70511574-001-01-0 | (E)-4-(2-(2-(N-Acetyl-N-((p-methoxyphenyl)sulfonyl)amino)phenyl)ethenyl)pyridine 1-oxide | a...
- SBE 13 hydrochloride● In Stock — US warehouse, ships to EU* Item #: S165662View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[[4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl]methyl]-2-(3,4-dimethoxyphenyl)ethanamine;hydrochloride
- SMILES
- COC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl
- InChIKey
- QBGSVDJLQQXEGG-UHFFFAOYSA-N
- InChI
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- Synonyms
- AC-3511 | SBE-13 HCl;SBE13 HCl | N-{4-[(6-chloro-3-pyridinyl)methoxy]-3-methoxybenzyl}-N-[2-(3,4-dimethoxyphenyl)ethy...
- LFM-A13● In Stock — US warehouse, ships to EU* Item #: L286934View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide
- SMILES
- CC(=C(C#N)C(=O)NC1=C(C=CC(=C1)Br)Br)O
- InChIKey
- UVSVTDVJQAJIFG-UHFFFAOYSA-N
- InChI
- 1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)
- Synonyms
- AKOS028108222 | alpha-Cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide | KBio3_001038 | HMS3370M16 | L...
- Volasertib (BI 6727), Inhibitor of polo like kinase 1Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%● In Stock — US warehouse, ships to EU* Item #: V126966View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl]-4-[[(7R)-7-ethyl-5-methyl-6-oxo-8-propan-2-yl-7H-pteridin-2-yl]amino]-3-methoxybenzamide
- SMILES
- CCC1C(=O)N(C2=CN=C(N=C2N1C(C)C)NC3=C(C=C(C=C3)C(=O)NC4CCC(CC4)N5CCN(CC5)CC6CC6)OC)C
- InChIKey
- SXNJFOWDRLKDSF-XKHVUIRMSA-N
- InChI
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- Synonyms
- BCPP000341 | DTXSID901025694 | Benzamide, N-(trans-4-(4-(cyclopropylmethyl)-1-piperazinyl)cyclohexyl)-4-(((7R)-7-ethy...
- Wortmannin, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: W100984View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C5=COC(=C54)C3=O)COC)C)C
- InChIKey
- QDLHCMPXEPAAMD-QAIWCSMKSA-N
- InChI
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- Synonyms
- BRN 0067676 | SCHEMBL4531 | ST-415 | (1S,6bR,9aS,11R,11bR)-1-(methoxymethyl)-9a,11b-dimethyl-3,6,9-trioxo-3,6,6b,7,8,...
- Cyclapolin 9CAS: 40533-25-3 Formula: C9H4F3N3O4S Molecular Weight: 307.21● In Stock — US warehouse, ships to EU* Item #: C286952View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-nitro-3-oxido-5-(trifluoromethyl)-1,3-benzothiazol-3-ium-2-carboxamide
- SMILES
- C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])C(F)(F)F
- InChIKey
- FHFLXKUKCSDMLD-UHFFFAOYSA-N
- InChI
- 1S/C9H4F3N3O4S/c10-9(11,12)3-1-4-6(5(2-3)15(18)19)20-8(7(13)16)14(4)17/h1-2H,(H2,13,16)
- Synonyms
- 7-Nitro-5-(trifluoromethyl)-2-benzothiazolecarboxamide-3-oxide | 2-carbamoyl-7-nitro-5-(trifluoromethyl)benzo[d]thiaz...
- PoloximeCAS: 17302-61-3 Formula: C10H13NO2 Molecular Weight: 179.22◐ .Made to order · 8–12 wks Item #: P125366View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-methyl-4-nitroso-2-propan-2-ylphenol
- SMILES
- CC1=CC(=C(C=C1N=O)C(C)C)O
- InChIKey
- YQVCMSSJMLGWAM-UHFFFAOYSA-N
- InChI
- 1S/C10H13NO2/c1-6(2)8-5-9(11-13)7(3)4-10(8)12/h4-6,12H,1-3H3
- Synonyms
- DTXSID9062350 | Phenol, 5-methyl-2-(1-methylethyl)-4-nitroso- | 2-Methyl-5-(1-Methylethyl)cyclohexa-2,5-Diene-1,4-Dio...
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Frequently Asked Questions
Which compounds are listed for Polo-like Kinase (PLK)?
Compounds associated with Polo-like Kinase (PLK) are grouped here under the Cell Cycle/DNA Damage classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Polo-like Kinase (PLK) sit within Cell Cycle/DNA Damage?
Polo-like Kinase (PLK) is one target listing within the Cell Cycle/DNA Damage classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Polo-like Kinase (PLK)?
For compounds listed under Polo-like Kinase (PLK), check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Polo-like Kinase (PLK)?
Browse the parent Cell Cycle/DNA Damage listing to reach targets neighbouring Polo-like Kinase (PLK), and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.