Poly(ADP-ribose) Glycohydrolase (PARG)

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  1. PDD 00017272
    CAS: 1945950-20-8 PubChem CID: 134169694 Formula: C23H25N5O4S3 Molecular Weight: 531.66
    ◐ .Made to order · 8–12 wks Item #: P287050
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    Technical Identifiers
    IUPAC Name
    1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-N-(1-methylcyclopropyl)-3-[(2-methyl-1,3-thiazol-5-yl)methyl]-2,4-dioxoquinazoline-6-sulfonamide
    SMILES
    CC1=C(SC(=N1)C)CN2C3=C(C=C(C=C3)S(=O)(=O)NC4(CC4)C)C(=O)N(C2=O)CC5=CN=C(S5)C
    InChIKey
    QOEXRJYTAZZRPL-UHFFFAOYSA-N
    InChI
    1S/C23H25N5O4S3/c1-13-20(34-15(3)25-13)12-27-19-6-5-17(35(31,32)26-23(4)7-8-23)9-18(19)21(29)28(22(27)30)11-16-10-24-14(2)33-16/h5-6,9-10,26H,7-8,11-1show more
    Synonyms
    1-[(2,4-Dimethyl-5-thiazolyl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-...
  2. PDD 00017273
    CAS: 1945950-21-9 PubChem CID: 121398766 Formula: C23H26N6O4S2 Molecular Weight: 514.62
    ● In Stock — US warehouse, ships to EU* Item #: P287939
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    IUPAC Name
    1-[(2,5-dimethylpyrazol-3-yl)methyl]-N-(1-methylcyclopropyl)-3-[(2-methyl-1,3-thiazol-5-yl)methyl]-2,4-dioxoquinazoline-6-sulfonamide
    SMILES
    CC1=NN(C(=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)NC4(CC4)C)C(=O)N(C2=O)CC5=CN=C(S5)C)C
    InChIKey
    IFWUBRBMMNTBRZ-UHFFFAOYSA-N
    InChI
    1S/C23H26N6O4S2/c1-14-9-16(27(4)25-14)12-28-20-6-5-18(35(32,33)26-23(3)7-8-23)10-19(20)21(30)29(22(28)31)13-17-11-24-15(2)34-17/h5-6,9-11,26H,7-8,12-1show more
    Synonyms
    1-[(1,3-Dimethyl-1H-pyrazol-5-yl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-...
  3. PDD 00017238
    CAS: 1952247-05-0 PubChem CID: 121415983 Formula: C19H20N6O3S3 Molecular Weight: 476.59
    ◐ .Made to order · 8–12 wks Item #: P286744
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    IUPAC Name
    1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)benzimidazole-5-sulfonamide
    SMILES
    CC1=C(SC(=N1)C)CN2C3=C(C=C(C=C3)S(=O)(=O)NC4(CC4)C)N(C2=O)C5=NC=NS5
    InChIKey
    FLUZEVGWXJVSPX-UHFFFAOYSA-N
    InChI
    1S/C19H20N6O3S3/c1-11-16(29-12(2)22-11)9-24-14-5-4-13(31(27,28)23-19(3)6-7-19)8-15(14)25(18(24)26)17-20-10-21-30-17/h4-5,8,10,23H,6-7,9H2,1-3H3
    Synonyms
    1-[(2,4-Dimethyl-5-thiazolyl)methyl]-2,3-dihydro-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)-1H-benzimida...
  4. PDD 00017273
    CAS: 1945950-21-9 PubChem CID: 121398766 Formula: C23H26N6O4S2 Molecular Weight: 514.62
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: P422376
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    Technical Identifiers
    IUPAC Name
    1-[(2,5-dimethylpyrazol-3-yl)methyl]-N-(1-methylcyclopropyl)-3-[(2-methyl-1,3-thiazol-5-yl)methyl]-2,4-dioxoquinazoline-6-sulfonamide
    SMILES
    CC1=NN(C(=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)NC4(CC4)C)C(=O)N(C2=O)CC5=CN=C(S5)C)C
    InChIKey
    IFWUBRBMMNTBRZ-UHFFFAOYSA-N
    InChI
    1S/C23H26N6O4S2/c1-14-9-16(27(4)25-14)12-28-20-6-5-18(35(32,33)26-23(3)7-8-23)10-19(20)21(30)29(22(28)31)13-17-11-24-15(2)34-17/h5-6,9-11,26H,7-8,12-1show more
    Synonyms
    1-[(1,3-Dimethyl-1H-pyrazol-5-yl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-...
  5. PDD 00031705
    CAS: 2032096-45-8 PubChem CID: 123131658 Formula: C20H22N6O3S3 Molecular Weight: 490.62
    ◐ .Made to order · 8–12 wks Item #: P288048
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    Technical Identifiers
    IUPAC Name
    1-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-N-methyl-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)benzimidazole-5-sulfonamide
    SMILES
    CC1=C(SC(=N1)C)CN2C3=C(C=C(C=C3)S(=O)(=O)N(C)C4(CC4)C)N(C2=O)C5=NC=NS5
    InChIKey
    KWGUETFSHQZXMA-UHFFFAOYSA-N
    InChI
    1S/C20H22N6O3S3/c1-12-17(30-13(2)23-12)10-25-15-6-5-14(32(28,29)24(4)20(3)7-8-20)9-16(15)26(19(25)27)18-21-11-22-31-18/h5-6,9,11H,7-8,10H2,1-4H3
    Synonyms
    1-[(2,4-Dimethyl-5-thiazolyl)methyl]-2,3-dihydro-N-methyl-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)-1H-...
  6. COH34
    CAS: 906439-72-3 PubChem CID: 135443632 Formula: C18H15NOS Molecular Weight: 293.38
    ◐ .Made to order · 8–12 wks Item #: C648836
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    IUPAC Name
    1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol
    SMILES
    CC1=CC=C(C=C1)SN=CC2=C(C=CC3=CC=CC=C32)O
    InChIKey
    SFUAIBHPGDRCFL-XDHOZWIPSA-N
    InChI
    1S/C18H15NOS/c1-13-6-9-15(10-7-13)21-19-12-17-16-5-3-2-4-14(16)8-11-18(17)20/h2-12,20H,1H3/b19-12+
  7. JA2131
    CAS: 6505-99-3 PubChem CID: 4361023 Formula: C13H19N5O2S2 Molecular Weight: 341.45
    ◐ .Made to order · 8–12 wks Item #: J650902
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    Technical Identifiers
    IUPAC Name
    1,3-dimethyl-8-(2-morpholin-4-ylethylsulfanyl)-6-sulfanylidene-7H-purin-2-one
    SMILES
    CN1C2=C(C(=S)N(C1=O)C)NC(=N2)SCCN3CCOCC3
    InChIKey
    XHNSOGDMSSHQFY-UHFFFAOYSA-N
    InChI
    1S/C13H19N5O2S2/c1-16-10-9(11(21)17(2)13(16)19)14-12(15-10)22-8-5-18-3-6-20-7-4-18/h3-8H2,1-2H3,(H,14,15)
    Synonyms
    EX-A5812 | DTXSID10402359 | NSC98003 | NSC-98003 | HY-137924 | SCHEMBL24559257 | JA2131 | 1,3-dimethyl-8-(2-morpholin...
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Frequently Asked Questions

How is the Poly(ADP-ribose) Glycohydrolase (PARG) listing put together?
It draws on reported Poly(ADP-ribose) Glycohydrolase (PARG) annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Poly(ADP-ribose) Glycohydrolase (PARG) modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Poly(ADP-ribose) Glycohydrolase (PARG) entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Poly(ADP-ribose) Glycohydrolase (PARG) compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Poly(ADP-ribose) Glycohydrolase (PARG) work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Poly(ADP-ribose) Glycohydrolase (PARG) compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Poly(ADP-ribose) Glycohydrolase (PARG) compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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