Proteasome

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  1. Isoginkgetin
    CAS: 548-19-6 Formula: C32H22O10 Molecular Weight: 566.51
    ● In Stock — US warehouse, ships to EU* Item #: I288348
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    IUPAC Name
    8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)chromen-4-one
    SMILES
    COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5=CC(=O)C6=C(C=C(C=C6O5)O)O)OC
    InChIKey
    HUOOMAOYXQFIDQ-UHFFFAOYSA-N
    InChI
    1S/C32H22O10/c1-39-18-6-3-15(4-7-18)26-14-24(38)31-22(36)12-21(35)29(32(31)42-26)19-9-16(5-8-25(19)40-2)27-13-23(37)30-20(34)10-17(33)11-28(30)41-27/hshow more
    Synonyms
    AS-56807 | CHEBI:79087 | KBio2_006022 | HY-N2117 | MFCD00597035 | BRD-K72661036-001-02-1 | KBioSS_000886 | 8-[5-(5,7-...
  2. Gabexate Mesylate
    CAS: 56974-61-9 Formula: C16H23N3O4·CH4O3S Molecular Weight: 417.48
    Solid ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: G129271
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    IUPAC Name
    ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;methanesulfonic acid
    SMILES
    CCOC(=O)C1=CC=C(C=C1)OC(=O)CCCCCN=C(N)N.CS(=O)(=O)O
    InChIKey
    DNTNDFLIKUKKOC-UHFFFAOYSA-N
    InChI
    1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4)
    Synonyms
    HMS3370J02 | ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;methanesulfonic acid | Gabexate mesilate (JP17)...
  3. MG-115
    CAS: 133407-86-0 Formula: C25H39N3O5 Molecular Weight: 461.59
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: M275487
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    IUPAC Name
    benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxopentan-2-yl]amino]pentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
    SMILES
    CCCC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
    InChIKey
    QEJRGURBLQWEOU-FKBYEOEOSA-N
    InChI
    1S/C25H39N3O5/c1-6-10-20(15-29)26-23(30)21(13-17(2)3)27-24(31)22(14-18(4)5)28-25(32)33-16-19-11-8-7-9-12-19/h7-9,11-12,15,17-18,20-22H,6,10,13-14,16H2show more
    Synonyms
    N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxopentan-2-yl]amino]pentan-2-yl]amino]-1-oxopentan-2-yl]carbamic...
  4. PD 151746
    CAS: 179461-52-0 PubChem CID: 5353866 Formula: C11H8FNO2S Molecular Weight: 237.25
    ● In Stock — US warehouse, ships to EU* Item #: P276048
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    IUPAC Name
    (Z)-3-(5-fluoro-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid
    SMILES
    C1=CC2=C(C=C1F)C(=CN2)C=C(C(=O)O)S
    InChIKey
    HWMQHECFXSVZGN-KMKOMSMNSA-N
    InChI
    1S/C11H8FNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3-
    Synonyms
    3-(5-Fluoro-1H-indol-3-yl)-2-mercapto-2-propenoicacid
  5. ONX-0914 (PR-957), Inhibitor of proteasome 20S subunit beta 8
    CAS: 960374-59-8 Formula: C31H40N4O7 Molecular Weight: 580.67
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: O127572
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    IUPAC Name
    (2S)-3-(4-methoxyphenyl)-N-[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]proshow more
    SMILES
    CC(C(=O)NC(CC1=CC=C(C=C1)OC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C)NC(=O)CN4CCOCC4
    InChIKey
    WQAVPPWWLLVGFK-VTNASVEKSA-N
    InChI
    1S/C31H40N4O7/c1-21(32-27(36)19-35-13-15-41-16-14-35)29(38)34-26(18-23-9-11-24(40-3)12-10-23)30(39)33-25(28(37)31(2)20-42-31)17-22-7-5-4-6-8-22/h4-12,show more
    Synonyms
    PR-957 | ONX 0914 | ONX0914 | PR957 | PR 957 | N-[2-(4-Morpholinyl)acetyl]-L-alanyl-O-methyl-N-[(1S)-2-[(2R)-2-methyl...
  6. MLN2238, 26S proteasome inhibitor
    CAS: 1072833-77-2 Formula: C14H19BCl2N2O4 Molecular Weight: 361.03
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: M128010
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    IUPAC Name
    [(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid
    SMILES
    B(C(CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O
    InChIKey
    MXAYKZJJDUDWDS-LBPRGKRZSA-N
    InChI
    1S/C14H19BCl2N2O4/c1-8(2)5-12(15(22)23)19-13(20)7-18-14(21)10-6-9(16)3-4-11(10)17/h3-4,6,8,12,22-23H,5,7H2,1-2H3,(H,18,21)(H,19,20)/t12-/m0/s1
    Synonyms
    ENT 25,543 | BCP9000953 | L01XX50 | MFCD18251438 | HY-10453 | BDBM50398609 | Q20948663 | DTXSID701025662 | Ixozamib |...
  7. Oprozomib (ONX 0912), 26S proteosome inhibitor
    CAS: 935888-69-0 PubChem CID: 25067547 Formula: C25H32N4O7S Molecular Weight: 532.61
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: O129260
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    IUPAC Name
    N-[(2S)-3-methoxy-1-[[(2S)-3-methoxy-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-show more
    SMILES
    CC1=NC=C(S1)C(=O)NC(COC)C(=O)NC(COC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)C
    InChIKey
    SWZXEVABPLUDIO-WSZYKNRRSA-N
    InChI
    1S/C25H32N4O7S/c1-15-26-11-20(37-15)24(33)29-19(13-35-4)23(32)28-18(12-34-3)22(31)27-17(21(30)25(2)14-36-25)10-16-8-6-5-7-9-16/h5-9,11,17-19H,10,12-14show more
    Synonyms
    ONX-0912 | PR-047 | J-690398 | N-((S)-3-methoxy-1-(((S)-3-methoxy-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylp...
  8. Calpain Inhibitor VI
    CAS: 190274-53-4 Formula: C17H25FN2O4S Molecular Weight: 372.5
    ◐ .Made to order · 8–12 wks Item #: C336446
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    IUPAC Name
    2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-(4-methyl-1-oxopentan-2-yl)butanamide
    SMILES
    CC(C)CC(C=O)NC(=O)C(C(C)C)NS(=O)(=O)C1=CC=C(C=C1)F
    InChIKey
    WSJWUIDLGZAXID-UHFFFAOYSA-N
    InChI
    1S/C17H25FN2O4S/c1-11(2)9-14(10-21)19-17(22)16(12(3)4)20-25(23,24)15-7-5-13(18)6-8-15/h5-8,10-12,14,16,20H,9H2,1-4H3,(H,19,22)
    Synonyms
    N-(4-Fluorophenylsulfonyl)-L-Valyl-L-Leucinal | 2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-(4-methyl-1-oxopentan-2-...
  9. Celastrol, Inhibitor of regulator of G-protein signaling 17
    CAS: 34157-83-0 EC Number: 636-472-5 Formula: C29H38O4 Molecular Weight: 450.61
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: C107671
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    IUPAC Name
    (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
    SMILES
    CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
    InChIKey
    KQJSQWZMSAGSHN-JJWQIEBTSA-N
    InChI
    1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(show more
    Synonyms
    (2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carbox...
  10. Calpain Inhibitor XII
    CAS: 181769-57-3 Formula: C26H34N4O5 Molecular Weight: 482.57
    ● In Stock — US warehouse, ships to EU* Item #: C341237
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    IUPAC Name
    benzyl N-[1-[[1,2-dioxo-1-(pyridin-2-ylmethylamino)hexan-3-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
    SMILES
    CCCC(C(=O)C(=O)NCC1=CC=CC=N1)NC(=O)C(CC(C)C)NC(=O)OCC2=CC=CC=C2
    InChIKey
    PLVWMBFPIAQRHK-UHFFFAOYSA-N
    InChI
    1S/C26H34N4O5/c1-4-10-21(23(31)25(33)28-16-20-13-8-9-14-27-20)29-24(32)22(15-18(2)3)30-26(34)35-17-19-11-6-5-7-12-19/h5-9,11-14,18,21-22H,4,10,15-17H2show more
    Synonyms
    (Rac)-Calpain Inhibitor XII | [3-methyl-1-[[[1-[oxo[(2-pyridinylmethyl)amino]acetyl]butyl]amino]carbonyl]butyl]-carba...
  11. 5-Amino-8-hydroxyquinoline(5A8HQ)
    CAS: 13207-66-4 EC Number: 108-775-8 Formula: C9H8N2O Molecular Weight: 160.17
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    ◐ .Made to order · 8–12 wks Item #: A181160
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    IUPAC Name
    5-aminoquinolin-8-ol
    SMILES
    C1=CC2=C(C=CC(=C2N=C1)O)N
    InChIKey
    YDEUKNRKEYICTH-UHFFFAOYSA-N
    InChI
    1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2
    Synonyms
    N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide, >=97.0% (GC) | SY045850 | 5-Aminooxin | BB 0221209 | 5-Amino-8-...
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Frequently Asked Questions

Which compounds are listed for Proteasome?
Compounds associated with Proteasome are grouped here under the Metabolic Enzyme/Protease classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Proteasome sit within Metabolic Enzyme/Protease?
Proteasome is one target listing within the Metabolic Enzyme/Protease classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Proteasome?
For compounds listed under Proteasome, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Proteasome?
Browse the parent Metabolic Enzyme/Protease listing to reach targets neighbouring Proteasome, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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