Pyroptosis

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  1. 2,3',4,4',5-Pentachlorobiphenyl Standard Solution
    CAS: 31508-00-6 PubChem CID: 35823 Formula: C12H5Cl5 Molecular Weight: 326.4
    100 μg/mL in n-hexane
    ● In Stock — US warehouse, ships to EU* Item #: P399192
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    IUPAC Name
    1,2,4-trichloro-5-(3,4-dichlorophenyl)benzene
    SMILES
    C1=CC(=C(C=C1C2=CC(=C(C=C2Cl)Cl)Cl)Cl)Cl
    InChIKey
    IUTPYMGCWINGEY-UHFFFAOYSA-N
    InChI
    1S/C12H5Cl5/c13-8-2-1-6(3-10(8)15)7-4-11(16)12(17)5-9(7)14/h1-5H
    Synonyms
    31508-00-6|2,3',4,4',5-PENTACHLOROBIPHENYL|PCB118|PCB 118|1,1'-Biphenyl, 2,3',4,4',5-pentachloro-|PCB No 118|3,4,2',4...
  2. 2,3',4,4',5-Pentachlorobiphenyl Standard Solution
    CAS: 31508-00-6 PubChem CID: 35823 Formula: C12H5Cl5 Molecular Weight: 326.4
    100 μg/mL in Methanol
    ● In Stock — US warehouse, ships to EU* Item #: P299599
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    IUPAC Name
    1,2,4-trichloro-5-(3,4-dichlorophenyl)benzene
    SMILES
    C1=CC(=C(C=C1C2=CC(=C(C=C2Cl)Cl)Cl)Cl)Cl
    InChIKey
    IUTPYMGCWINGEY-UHFFFAOYSA-N
    InChI
    1S/C12H5Cl5/c13-8-2-1-6(3-10(8)15)7-4-11(16)12(17)5-9(7)14/h1-5H
    Synonyms
    31508-00-6|2,3',4,4',5-PENTACHLOROBIPHENYL|PCB118|PCB 118|1,1'-Biphenyl, 2,3',4,4',5-pentachloro-|PCB No 118|3,4,2',4...
  3. Nigericin sodium salt
    CAS: 28643-80-3 EC Number: 608-231-4 PubChem CID: 16760591 Formula: C40H67NaO11 Molecular Weight: 746.94
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: N102401
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    IUPAC Name
    sodium;(2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyshow more
    SMILES
    CC1CCC(OC1C(C)C(=O)[O-])CC2CC(C(C3(O2)C(CC(O3)(C)C4CCC(O4)(C)C5C(CC(O5)C6C(CC(C(O6)(CO)O)C)C)C)C)C)OC.[Na+]
    InChIKey
    MOYOTUKECQMGHE-PDEFJWSRSA-M
    InChI
    1S/C40H68O11.Na/c1-21-11-12-28(46-33(21)26(6)36(42)43)17-29-18-30(45-10)27(7)40(48-29)25(5)19-38(9,51-40)32-13-14-37(8,49-32)35-23(3)16-31(47-35)34-22show more
    Synonyms
    NIGERICIN, MONOSODIUM SALT | Q27276393 | NIGERICIN SODIUM SALT [MI] | Nigericin, sodium salt (1:1) | Nigericin (sodiu...
  4. D-Aspartic acid, Excitatory amino acid transporter 1;Excitatory amino acid transporter 2;Excitatory amino acid transporter 3;Excitatory amino acid transporter 4;Excitatory amino acid transporter 5;Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agon
    CAS: 1783-96-6 EC Number: 217-234-6 Formula: C4H7NO4 Molecular Weight: 133.10
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — Germany Item #: A105951
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    IUPAC Name
    (2R)-2-aminobutanedioic acid
    SMILES
    C(C(C(=O)O)N)C(=O)O
    InChIKey
    CKLJMWTZIZZHCS-UWTATZPHSA-N
    InChI
    1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
    Synonyms
    2,2'-methanediylbis(1H-benzimidazole) | 6-benzyloxy-1H-indole | C4H7NO4 | delta-aspartate | SR-01000597731 | C00402 |...
  5. Ethyl pyruvate
    CAS: 617-35-6 EC Number: 210-511-2 Formula: C5H8O3 Molecular Weight: 116.12
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: E113332
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    IUPAC Name
    ethyl 2-oxopropanoate
    SMILES
    CCOC(=O)C(=O)C
    InChIKey
    XXRCUYVCPSWGCC-UHFFFAOYSA-N
    InChI
    1S/C5H8O3/c1-3-8-5(7)4(2)6/h3H2,1-2H3
    Synonyms
    Ethyl methylglyoxylate | 2-oxopropanoic acid ethyl ester | Ethyl 2-oxopropanoate | Ethyl 2-oxopropionate | Methyl eth...
  6. Morroniside
    CAS: 25406-64-8 Formula: C17H26O11 Molecular Weight: 406.38
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: M303231
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    IUPAC Name
    methyl (1S,3R,4aS,8S,8aS)-3-hydroxy-1-methyl-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,3,4,4a,8,8a-hexahydropyrano[3,4-c]pshow more
    SMILES
    CC1C2C(CC(O1)O)C(=COC2OC3C(C(C(C(O3)CO)O)O)O)C(=O)OC
    InChIKey
    YTZSBJLNMIQROD-SFBCHFHNSA-N
    InChI
    1S/C17H26O11/c1-6-11-7(3-10(19)26-6)8(15(23)24-2)5-25-16(11)28-17-14(22)13(21)12(20)9(4-18)27-17/h5-7,9-14,16-22H,3-4H2,1-2H3/t6-,7+,9+,10+,11+,12+,13show more
    Synonyms
    CCG-268714 | C17000 | DTXSID60948257 | s5465 | Methyl 8-(hexopyranosyloxy)-3-hydroxy-1-methyl-4,4a,8,8a-tetrahydro-1H...
  7. Tetraethylthiuram disulfide(TETD), Aldehyde dehydrogenase inhibitor
    CAS: 97-77-8 EC Number: 202-607-8 Formula: C10H20N2S4 Molecular Weight: 296.54
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — Germany Item #: T110101
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    IUPAC Name
    diethylcarbamothioylsulfanyl N,N-diethylcarbamodithioate
    SMILES
    CCN(CC)C(=S)SSC(=S)N(CC)CC
    InChIKey
    AUZONCFQVSMFAP-UHFFFAOYSA-N
    InChI
    1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3
    Synonyms
    TETD | Disulfiram | Contrapot | Ethyl tuads | Tetraethylthiuram disulfide | CHEBI:4659 | Ethyl Thiudad | Hoca | NSC 1...
  8. Sodium metatungstate(POM-1)
    CAS: 12141-67-2 EC Number: 412-770-9 PubChem CID: 71311259 Formula: H2O40Na6W12 Molecular Weight: 2986.01
    ● In Stock — US warehouse, ships to EU* Item #: P287759
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    Technical Identifiers
    SMILES
    O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.[O-]show more
    InChIKey
    YVQUUPJGDSQKML-UHFFFAOYSA-N
    Synonyms
    hexa-Sodium tungstate (W12) | Sodium polytungstate
  9. cis-Diammineplatinum dichloride
    CAS: 15663-27-1 EC Number: 239-733-8 Formula: H6Cl2N2Pt Molecular Weight: 300.1
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Pt,65%
    ● In Stock — US warehouse, ships to EU* Item #: D109812
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    SMILES
    N.N.Cl[Pt]Cl
    InChIKey
    LXZZYRPGZAFOLE-UHFFFAOYSA-L
    InChI
    1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
    Synonyms
    Cisplatin
  10. cis-Diammineplatinum dichloride
    CAS: 15663-27-1 EC Number: 239-733-8 Formula: H6Cl2N2Pt Molecular Weight: 300.1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99.5%
    ● In Stock — US warehouse, ships to EU* Item #: C295225
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    SMILES
    N.N.Cl[Pt]Cl
    InChIKey
    LXZZYRPGZAFOLE-UHFFFAOYSA-L
    InChI
    1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
    Synonyms
    Cisplatin | cis-Dichlorodiammine platinum(II) | cis-Platinum(II) diammine dichloride | cis-Diammineplatinum(II) dichl...
  11. 2-Bromohexadecanoic acid
    CAS: 18263-25-7 EC Number: 242-137-0 Formula: CH3(CH2)13CH(Br)CO2H Molecular Weight: 335.32
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: B135567
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    IUPAC Name
    2-bromohexadecanoic acid
    SMILES
    CCCCCCCCCCCCCCC(C(=O)O)Br
    InChIKey
    DPRAYRYQQAXQPE-UHFFFAOYSA-N
    InChI
    1S/C16H31BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19)
    Synonyms
    CAS-18263-25-7 | CHEBI:133152 | NCGC00164251-02 | PD165437 | FT-0611564 | SCHEMBL97565 | LMFA01090011 | Spiro(isobenz...
  12. Sodium metatungstate hydrate
    CAS: 314075-43-9 EC Number: 412-770-9 Formula: 3Na2WO4·9WO3·xH2O Molecular Weight: 2968.00 (anhydrous basis)
    W, 70%
    ● In Stock — US warehouse, ships to EU* Item #: S342348
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    IUPAC Name
    hexasodium;hydroxy-[(oxido(dioxo)tungstenio)oxy-dioxotungstenio]oxy-dioxotungsten;hydroxy-[[(oxido(dioxo)tungstenio)oxy-dioxotungstenio]oxy-dioxotungsshow more
    SMILES
    O.[OH-].[OH-].[OH-].O[W](=O)(=O)O[W](=O)(=O)O[W](=O)(=O)[O-].O[W](=O)(=O)O[W](=O)(=O)O[W](=O)(=O)O[W](=O)(=O)[O-].O[W](=O)(=O)O[W](=O)(=O)O[W](=O)(=O)show more
    InChIKey
    ZHHYGMAYHOPMBY-UHFFFAOYSA-H
    InChI
    1S/6Na.7H2O.33O.12W/h;;;;;;7*1H2;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/q6*+1;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;3*-1;;;;;;;;;;3*+1/p-6
    Synonyms
    Hexasodium;hydroxy-[(oxido(dioxo)tungstenio)oxy-dioxotungstenio]oxy-dioxotungsten;hydroxy-[[(oxido(dioxo)tungstenio)o...
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Frequently Asked Questions

How is the Pyroptosis listing put together?
It draws on reported Pyroptosis annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Pyroptosis modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Pyroptosis entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Pyroptosis compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Pyroptosis work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Pyroptosis compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Pyroptosis compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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