RAD51

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  1. Amuvatinib (MP-470), Platelet-derived growth factor receptor alpha inhibitor
    CAS: 850879-09-3 Formula: C23H21N5O3S Molecular Weight: 447.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: M127412
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    IUPAC Name
    N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide
    SMILES
    C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6
    InChIKey
    FOFDIMHVKGYHRU-UHFFFAOYSA-N
    InChI
    1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,2show more
    Synonyms
    N-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide | NSC754349 | NSC-75...
  2. Disodium 4,4'-Diisothiocyanato -2,2'-stilbenedisulfonate Hydrate
    CAS: 67483-13-0 EC Number: 679-841-6 Formula: C16H8N2Na2O6S4 Molecular Weight: 498.47
    ● In Stock — US warehouse, ships to EU* Item #: D131281
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    IUPAC Name
    disodium;5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfonatophenyl)ethenyl]benzenesulfonate
    SMILES
    C1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])C=CC2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-].[Na+].[Na+]
    InChIKey
    GEPAYBXVXXBSKP-SEPHDYHBSA-L
    InChI
    1S/C16H10N2O6S4.2Na/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24;;/h1-8H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2/b2show more
    Synonyms
    4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt | 4,4'-diisothiocyanatostilbene-2,2'-disul-fonic aci...
  3. RI-1
    CAS: 415713-60-9 PubChem CID: 1074953 Formula: C14H11Cl3N2O3 Molecular Weight: 361.61
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: R125517
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    IUPAC Name
    3-chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione
    SMILES
    C1COCCN1C2=C(C(=O)N(C2=O)C3=CC(=C(C=C3)Cl)Cl)Cl
    InChIKey
    MWSUIZKGNWELRF-UHFFFAOYSA-N
    InChI
    1S/C14H11Cl3N2O3/c15-9-2-1-8(7-10(9)16)19-13(20)11(17)12(14(19)21)18-3-5-22-6-4-18/h1-2,7H,3-6H2
    Synonyms
    Q18392915 | HY-15317 | STL503566 | NCGC00371132-01 | RI1 | RI-1 | RI-1 (chemical) | RAD51 inhibitor 1 | UNII-S8WG8ZRQ...
  4. B02
    CAS: 1290541-46-6 EC Number: 802-984-4 Formula: C22H17N3O Molecular Weight: 339.39
    ● In Stock — US warehouse, ships to EU* Item #: B276133
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    IUPAC Name
    3-benzyl-2-[(E)-2-pyridin-3-ylethenyl]quinazolin-4-one
    SMILES
    C1=CC=C(C=C1)CN2C(=NC3=CC=CC=C3C2=O)C=CC4=CN=CC=C4
    InChIKey
    GEKDQXSPTHHANP-OUKQBFOZSA-N
    InChI
    1S/C22H17N3O/c26-22-19-10-4-5-11-20(19)24-21(13-12-17-9-6-14-23-15-17)25(22)16-18-7-2-1-3-8-18/h1-15H,16H2/b13-12+
    Synonyms
    cid_5738263 | RAD51 inhibitor B02 | B02; B-02; B 02; RAD51-IN-02 | SR-01000722866 | s8434 | BDBM48804 | RAD51 Inhibit...
  5. 4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamide
    CAS: 312756-74-4 Formula: C20H16Br2N2O3S Molecular Weight: 524.23
    ● In Stock — US warehouse, ships to EU* Item #: B137570
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    IUPAC Name
    3-(benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide
    SMILES
    C1=CC=C(C=C1)CNS(=O)(=O)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)Br)Br
    InChIKey
    SWKAVEUTKGKHSR-UHFFFAOYSA-N
    InChI
    1S/C20H16Br2N2O3S/c21-16-7-9-17(10-8-16)24-20(25)15-6-11-18(22)19(12-15)28(26,27)23-13-14-4-2-1-3-5-14/h1-12,23H,13H2,(H,24,25)
    Synonyms
    3-[(benzylamino)sulfonyl]-4-bromo-N-(4-bromophenyl)benzamide | AC-35367 | 3-(N-Benzylsulfamoyl)-4-bromo-N-(4-bromophe...
  6. 4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamide
    CAS: 312756-74-4 EC Number: 683-710-9 Formula: C20H16Br2N2O3S Molecular Weight: 524.23
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B423223
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    Technical Identifiers
    IUPAC Name
    3-(benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide
    SMILES
    C1=CC=C(C=C1)CNS(=O)(=O)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)Br)Br
    InChIKey
    SWKAVEUTKGKHSR-UHFFFAOYSA-N
    InChI
    1S/C20H16Br2N2O3S/c21-16-7-9-17(10-8-16)24-20(25)15-6-11-18(22)19(12-15)28(26,27)23-13-14-4-2-1-3-5-14/h1-12,23H,13H2,(H,24,25)
    Synonyms
    3-[(benzylamino)sulfonyl]-4-bromo-N-(4-bromophenyl)benzamide | AC-35367 | 3-(N-Benzylsulfamoyl)-4-bromo-N-(4-bromophe...
  7. B02
    CAS: 1290541-46-6 EC Number: 802-984-4 Formula: C22H17N3O Molecular Weight: 339.39
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B421153
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    Technical Identifiers
    IUPAC Name
    3-benzyl-2-[(E)-2-pyridin-3-ylethenyl]quinazolin-4-one
    SMILES
    C1=CC=C(C=C1)CN2C(=NC3=CC=CC=C3C2=O)C=CC4=CN=CC=C4
    InChIKey
    GEKDQXSPTHHANP-OUKQBFOZSA-N
    InChI
    1S/C22H17N3O/c26-22-19-10-4-5-11-20(19)24-21(13-12-17-9-6-14-23-15-17)25(22)16-18-7-2-1-3-8-18/h1-15H,16H2/b13-12+
    Synonyms
    cid_5738263 | RAD51 inhibitor B02 | B02; B-02; B 02; RAD51-IN-02 | SR-01000722866 | s8434 | BDBM48804 | RAD51 Inhibit...
  8. Bractoppin
    CAS: 2290527-07-8 Formula: C25H23FN4O Molecular Weight: 414.47
    ● In Stock — US warehouse, ships to EU* Item #: B413015
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    IUPAC Name
    [4-[(2-fluorophenyl)methyl]piperazin-1-yl]-(2-phenyl-3H-benzimidazol-5-yl)methanone
    SMILES
    C1CN(CCN1CC2=CC=CC=C2F)C(=O)C3=CC4=C(C=C3)N=C(N4)C5=CC=CC=C5
    InChIKey
    UHDGSNOZRAAGIZ-UHFFFAOYSA-N
    InChI
    1S/C25H23FN4O/c26-21-9-5-4-8-20(21)17-29-12-14-30(15-13-29)25(31)19-10-11-22-23(16-19)28-24(27-22)18-6-2-1-3-7-18/h1-11,16H,12-15,17H2,(H,27,28)
    Synonyms
    (4-(2-Fluorobenzyl)piperazin-1-yl)(2-phenyl-1H-benzo[d]imidazol-6-yl)methanone
  9. RI-1
    CAS: 415713-60-9 PubChem CID: 1074953 Formula: C14H11Cl3N2O3 Molecular Weight: 361.61
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: R423882
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    Technical Identifiers
    IUPAC Name
    3-chloro-1-(3,4-dichlorophenyl)-4-morpholin-4-ylpyrrole-2,5-dione
    SMILES
    C1COCCN1C2=C(C(=O)N(C2=O)C3=CC(=C(C=C3)Cl)Cl)Cl
    InChIKey
    MWSUIZKGNWELRF-UHFFFAOYSA-N
    InChI
    1S/C14H11Cl3N2O3/c15-9-2-1-8(7-10(9)16)19-13(20)11(17)12(14(19)21)18-3-5-22-6-4-18/h1-2,7H,3-6H2
    Synonyms
    Q18392915 | HY-15317 | STL503566 | NCGC00371132-01 | RI1 | RI-1 | RI-1 (chemical) | RAD51 inhibitor 1 | UNII-S8WG8ZRQ...
  10. DIDS, Channel blocker of CaCC;Channel blocker of ClC-6;Channel blocker of ClC-7;Channel blocker of ClC-Ka;Channel blocker of ClC-Kb
    CAS: 53005-05-3 PubChem CID: 40600
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: D609876
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    IUPAC Name
    5-isothiocyanato-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzene-1-sulfonic acid
    SMILES
    S=C=Nc1ccc(c(c1)S(=O)(=O)O)C=Cc1ccc(cc1S(=O)(=O)O)N=C=S
    InChIKey
    YSCNMFDFYJUPEF-UHFFFAOYSA-N
    InChI
    1S/C16H10N2O6S4/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24/h1-8H,(H,19,20,21)(H,22,23,24)
    Synonyms
    DTXSID20164976 | GTPL4177 | QHR3Z2PN8M | ABC inhibitor 2 | UNII-QHR3Z2PN8M | Benzenesulfonic acid, 2,2'-(1,2-ethenedi...
  11. Guaiol
    CAS: 489-86-1 PubChem CID: 227829 Formula: C15H26O Molecular Weight: 222.37
    ● In Stock — US warehouse, ships to EU* Item #: G646994
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    IUPAC Name
    2-[(3S,5R,8S)-3,8-dimethyl-1,2,3,4,5,6,7,8-octahydroazulen-5-yl]propan-2-ol
    SMILES
    CC1CCC(CC2=C1CCC2C)C(C)(C)O
    InChIKey
    TWVJWDMOZJXUID-SDDRHHMPSA-N
    InChI
    1S/C15H26O/c1-10-5-7-12(15(3,4)16)9-14-11(2)6-8-13(10)14/h10-12,16H,5-9H2,1-4H3/t10-,11-,12+/m0/s1
    Synonyms
    DTXSID40883399 | MFCD00043336 | SR-05000002468-1 | HY-N3980 | 5-Azulenemethanol, 1,2,3,4,5,6,7,8-octahydro-alpha,alph...
  12. IBR2
    CAS: 313526-24-8 PubChem CID: 4664423 Formula: C24H20N2O2S Molecular Weight: 400.5
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: I646314
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    Technical Identifiers
    IUPAC Name
    2-benzylsulfonyl-1-(1H-indol-3-yl)-1H-isoquinoline
    SMILES
    C1=CC=C(C=C1)CS(=O)(=O)N2C=CC3=CC=CC=C3C2C4=CNC5=CC=CC=C54
    InChIKey
    YCOHEPDJLXZVBZ-UHFFFAOYSA-N
    InChI
    1S/C24H20N2O2S/c27-29(28,17-18-8-2-1-3-9-18)26-15-14-19-10-4-5-11-20(19)24(26)22-16-25-23-13-7-6-12-21(22)23/h1-16,24-25H,17H2
    Synonyms
    2-(Benzylsulfonyl)-1-(1H-indol-3-yl)-1,2-dihydroisoquinoline
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Frequently Asked Questions

How is the RAD51 listing put together?
It draws on reported RAD51 annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a RAD51 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the RAD51 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for RAD51 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For RAD51 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the RAD51 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of RAD51 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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