Raf

Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.

115 products

Popular Products

View as List Grid

Showing 1-12 of 115

Set Descending Direction
  1. ZM 336372, Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    CAS: 208260-29-1 EC Number: 106-467-8 PubChem CID: 5730 Formula: C23H23N3O3 Molecular Weight: 389.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: Z129624
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]benzamide
    SMILES
    CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O
    InChIKey
    PYEFPDQFAZNXLI-UHFFFAOYSA-N
    InChI
    1S/C23H23N3O3/c1-15-7-10-18(24-23(29)17-5-4-6-19(13-17)26(2)3)14-21(15)25-22(28)16-8-11-20(27)12-9-16/h4-14,27H,1-3H3,(H,24,29)(H,25,28)
    Synonyms
    Bio1_001346 | Q27089299 | BiomolKI2_000059 | KBioSS_000580 | SMR004702983 | NCGC00025109-02 | ZINC00581684 | Benzamid...
  2. B-Raf inhibitor 1 dihydrochloride
    CAS: 1191385-19-9 PubChem CID: 44247765 Formula: C26H21Cl3N8 Molecular Weight: 551.86
    ● In Stock — US warehouse, ships to EU* Item #: I172449
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-N-(4-chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine;dihydrochloride
    SMILES
    CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6.Cl.Cl
    InChIKey
    HRLQRNBAJCQMMG-UHFFFAOYSA-N
    InChI
    1S/C26H19ClN8.2ClH/c1-15-4-9-19-18(10-12-29-24(19)34-17-7-5-16(27)6-8-17)21(15)35-25-20(3-2-11-28-25)22-23-26(32-13-30-22)33-14-31-23;;/h2-14H,1H3,(H,show more
    Synonyms
    1-N-(4-chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine | dihydrochloride
  3. GW5074, Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    CAS: 220904-83-6 Formula: C15H8Br2INO2 Molecular Weight: 520.94
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: G129612
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (3Z)-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1H-indol-2-one
    SMILES
    C1=CC2=C(C=C1I)C(=CC3=CC(=C(C(=C3)Br)O)Br)C(=O)N2
    InChIKey
    LMXYVLFTZRPNRV-KMKOMSMNSA-N
    InChI
    1S/C15H8Br2INO2/c16-11-4-7(5-12(17)14(11)20)3-10-9-6-8(18)1-2-13(9)19-15(10)21/h1-6,20H,(H,19,21)/b10-3-
    Synonyms
    Q27077947 | (3Z)-3-[(3,5-dibromo-4-hydroxy-phenyl)methylene]-5-iodo-indolin-2-one | GW 5074 | Lopac0_000510 | 5-iodo-...
  4. RRD-251 hydrochloride
    CAS: 72214-67-6 PubChem CID: 12526767 Formula: C8H8Cl2N2S· HCl Molecular Weight: 271.59
    ● In Stock — US warehouse, ships to EU* Item #: R338914
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (2,4-dichlorophenyl)methyl carbamimidothioate;hydrochloride
    SMILES
    C1=CC(=C(C=C1Cl)Cl)CSC(=N)N.Cl
    InChIKey
    COMNQRICZGJVLE-UHFFFAOYSA-N
    InChI
    1S/C8H8Cl2N2S.ClH/c9-6-2-1-5(7(10)3-6)4-13-8(11)12;/h1-3H,4H2,(H3,11,12);1H
    Synonyms
    2,4-dichlorobenzyl imidothiocarbamate hydrochloride | (2,4-Dichlorophenyl)carbamimidothioic acid methyl ester hydroch...
  5. RAF265 (CHIR-265), Vascular endothelial growth factor receptor 2 inhibitor
    CAS: 927880-90-8 PubChem CID: 11656518 Formula: C24H16F6N6O Molecular Weight: 518.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: R127906
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine
    SMILES
    CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
    InChIKey
    YABJJWZLRMPFSI-UHFFFAOYSA-N
    InChI
    1S/C24H16F6N6O/c1-36-19-7-6-15(10-17(19)34-22(36)33-14-4-2-13(3-5-14)23(25,26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28,29)30/h2-12H,1H3,(H,32,show more
    Synonyms
    CHIR265 | CHIR-265 | FT-0746327 | HMS3672I21 | NCGC00015003-02 | 1-methyl-5-[2-(5-trifluoromethyl-1H-imidazol-2-yl)py...
  6. PLX-4720, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of kinase insert domain receptor
    CAS: 918505-84-7 EC Number: 894-417-2 Formula: C17H14ClF2N3O3S Molecular Weight: 413.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: P127903
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide
    SMILES
    CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)Cl)F
    InChIKey
    YZDJQTHVDDOVHR-UHFFFAOYSA-N
    InChI
    1S/C17H14ClF2N3O3S/c1-2-5-27(25,26)23-13-4-3-12(19)14(15(13)20)16(24)11-8-22-17-10(11)6-9(18)7-21-17/h3-4,6-8,23H,2,5H2,1H3,(H,21,22)
    Synonyms
    AKOS015919071 | N-[3-(5-Chloro-7-azaindole-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide | HMS3750K11 | N-[3-(...
  7. Regorafenib (BAY 73-4506), Nerve growth factor receptor Trk-A
    CAS: 755037-03-7 EC Number: 815-051-1 PubChem CID: 11167602 Formula: C21H15ClF4N4O3 Molecular Weight: 482.82
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: R127804
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
    SMILES
    CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
    InChIKey
    FNHKPVJBJVTLMP-UHFFFAOYSA-N
    InChI
    1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32show more
    Synonyms
    CCG-269571 | AB00076187-01 | CHEBI:68647 | 755037-03-7 , Regorafenib | AC-25075 | MFCD16038047 | Regorafenib,BAY 73-4...
  8. SB590885
    CAS: 405554-55-4 PubChem CID: 135421339 Formula: C27H27N5O2 Molecular Weight: 453.54
    ● In Stock — US warehouse, ships to EU* Item #: S125513
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (NE)-N-[5-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl]-2,3-dihydroinden-1-ylidene]hydroxylamine
    SMILES
    CN(C)CCOC1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC5=C(C=C4)C(=NO)CC5
    InChIKey
    MLSAQOINCGAULQ-QFMPWRQOSA-N
    InChI
    1S/C27H27N5O2/c1-32(2)15-16-34-22-7-3-19(4-8-22)27-29-25(18-11-13-28-14-12-18)26(30-27)21-5-9-23-20(17-21)6-10-24(23)31-33/h3-5,7-9,11-14,17,33H,6,10,show more
    Synonyms
    SB-590885 | SB 590885 | 5-[2-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-1H-ind...
  9. Rafoxanide
    CAS: 22662-39-1 EC Number: 245-148-9 PubChem CID: 31475 Formula: C19H11Cl2I2NO3 Molecular Weight: 626.01
    ● In Stock — US warehouse, ships to EU* Item #: R136130
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[3-chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide
    SMILES
    C1=CC(=CC=C1OC2=C(C=C(C=C2)NC(=O)C3=C(C(=CC(=C3)I)I)O)Cl)Cl
    InChIKey
    NEMNPWINWMHUMR-UHFFFAOYSA-N
    InChI
    1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)
    Synonyms
    BDBM50022832 | Q12048733 | STK377482 | NEMNPWINWMHUMR-UHFFFAOYSA-N | SMR000768692 | N-(3-chloro-4-(4-chlorophenoxy) |...
  10. L-779450, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    CAS: 303727-31-3 Formula: C20H14ClN3O Molecular Weight: 347.8
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: L169419
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-chloro-5-(2-phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenol
    SMILES
    C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC(=C(C=C4)Cl)O
    InChIKey
    WXJLXRNWMLWVFB-UHFFFAOYSA-N
    InChI
    1S/C20H14ClN3O/c21-16-7-6-15(12-17(16)25)19-18(13-8-10-22-11-9-13)23-20(24-19)14-4-2-1-3-5-14/h1-12,25H,(H,23,24)
    Synonyms
    2-chloro-5-(2-phenyl-5-pyridin-4-yl-1H-imidazol-4-yl)phenol | HMS2847J19 | BDBM26041 | SCHEMBL7643418 | AC-35772 | HY...
  11. Vemurafenib (PLX4032, RG7204), Serine/threonine-protein kinase B-raf inhibitor
    CAS: 918504-65-1 EC Number: 850-250-7 PubChem CID: 42611257 Formula: C23H18ClF2N3O3S Molecular Weight: 489.92
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: V127521
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]propane-1-sulfonamide
    SMILES
    CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)Cl)F
    InChIKey
    GPXBXXGIAQBQNI-UHFFFAOYSA-N
    InChI
    1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,show more
    Synonyms
    1-Propanesulfonamide, N-(3-((5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)- | 207SMY...
  12. Locostatin
    CAS: 90719-30-5 Formula: C14H15NO3 Molecular Weight: 245.27
    ● In Stock — US warehouse, ships to EU* Item #: L171287
    View Product
    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (4S)-4-benzyl-3-[(E)-but-2-enoyl]-1,3-oxazolidin-2-one
    SMILES
    CC=CC(=O)N1C(COC1=O)CC2=CC=CC=C2
    InChIKey
    UTZAFVPPWUIPBH-QSLRECBCSA-N
    InChI
    1S/C14H15NO3/c1-2-6-13(16)15-12(10-18-14(15)17)9-11-7-4-3-5-8-11/h2-8,12H,9-10H2,1H3/b6-2+/t12-/m0/s1
    Synonyms
    AKOS024462522 | AKOS015913245 | AMY25984 | HY-W013411 | HY-W013411A | A843619 | SCHEMBL5058893 | (N-Crotonyl)-(4S)-be...
Page
per page
🚚
Fast Shipping Same-day shipping on in-stock items
📋
Technical Details Quality & specification info on every product page
📦
Pack Size Options Multiple packaging sizes with pricing access from listing
🔬
R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under Raf?
This listing collects compounds associated with Raf within our MAPK/ERK Pathway area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Raf?
Consider the reported potency of each Raf compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Raf compounds?
Each Raf product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Raf compounds by activity or structure?
Yes. Filter the Raf listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.