RET
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103 products
Popular Products
- RPI-1≥98% mixture of isomers,● In Stock — US warehouse, ships to EU* Item #: R337832View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3Z)-3-[(4-hydroxyphenyl)methylidene]-5,6-dimethoxy-1H-indol-2-one
- SMILES
- COC1=C(C=C2C(=C1)C(=CC3=CC=C(C=C3)O)C(=O)N2)OC
- InChIKey
- JGSMCYNBVCGIHC-QPEQYQDCSA-N
- InChI
- 1S/C17H15NO4/c1-21-15-8-12-13(7-10-3-5-11(19)6-4-10)17(20)18-14(12)9-16(15)22-2/h3-9,19H,1-2H3,(H,18,20)/b13-7-
- Synonyms
- RPI1 | RPI-1 | 2H-Indol-2-one, 1,3-dihydro-3-[(4-hydroxyphenyl)methylene]-5,6-dimethoxy- | HY-101246 | MFCD03852474 |...
- Regorafenib (BAY 73-4506), Nerve growth factor receptor Trk-ACAS: 755037-03-7 EC Number: 815-051-1 PubChem CID: 11167602 Formula: C21H15ClF4N4O3 Molecular Weight: 482.82Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: R127804View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
- SMILES
- CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
- InChIKey
- FNHKPVJBJVTLMP-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- CCG-269571 | AB00076187-01 | CHEBI:68647 | 755037-03-7 , Regorafenib | AC-25075 | MFCD16038047 | Regorafenib,BAY 73-4...
- SPP 86CAS: 1357349-91-7 EC Number: 110-164-6 PubChem CID: 66549796 Formula: C16H15N5 Molecular Weight: 277.32Solid ≥98%(HPLC)● In Stock — US warehouse, ships to EU* Item #: S288209View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-(2-phenylethynyl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine
- SMILES
- CC(C)N1C2=NC=NC(=C2C(=N1)C#CC3=CC=CC=C3)N
- InChIKey
- JQOIRTDBHMDWMT-UHFFFAOYSA-N
- InChI
- 1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7,10-11H,1-2H3,(H2,17,18,19)
- Synonyms
- SPP8 | 1-Isopropyl-3-(phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 1-(1-Methylethyl)-3-(2-phenylethynyl)-1H-p...
- PF-477736, Inhibitor of checkpoint kinase 1;Inhibitor of checkpoint kinase 2CAS: 952021-60-2 Formula: C22H25N7O2 Molecular Weight: 419.48Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P120184View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2R)-2-amino-2-cyclohexyl-N-[2-(1-methylpyrazol-4-yl)-9-oxo-3,10,11-triazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),11-pentaen-6-yl]acetamide
- SMILES
- CN1C=C(C=N1)C2=C3C=NNC(=O)C4=C3C(=CC(=C4)NC(=O)C(C5CCCCC5)N)N2
- InChIKey
- NDEXUOWTGYUVGA-LJQANCHMSA-N
- InChI
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- Synonyms
- (2R)-2-amino-2-cyclohexyl-N-[2-(1-methyl-1H-pyrazol-4-yl)-9-oxo-3,10,11-triazatricyclo[6.4.1.0,4,13]trideca-1,4(13),5...
- Lenvatinib (E7080), Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: L125518View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
- SMILES
- COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
- InChIKey
- WOSKHXYHFSIKNG-UHFFFAOYSA-N
- InChI
- 1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)
- Synonyms
- LENVATINIB [MI] | UNII-EE083865G2 | AS-16203 | LEV | NSC800781 | NSC-800781 | DB09078 | AKOS021983298 | LENVATINIB [I...
- Amuvatinib (MP-470), Platelet-derived growth factor receptor alpha inhibitorCAS: 850879-09-3 Formula: C23H21N5O3S Molecular Weight: 447.52Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: M127412View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide
- SMILES
- C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6
- InChIKey
- FOFDIMHVKGYHRU-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide | NSC754349 | NSC-75...
- AD80CAS: 1384071-99-1 Formula: C22H19F4N7O Molecular Weight: 473.44● In Stock — US warehouse, ships to EU* Item #: A275119View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[4-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
- SMILES
- CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)N
- InChIKey
- CYORWDWRQMVGHN-UHFFFAOYSA-N
- InChI
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- Synonyms
- N-[4-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea
- TG101209● In Stock — US warehouse, ships to EU* Item #: T127523View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-tert-butyl-3-[[5-methyl-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide
- SMILES
- CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)N4CCN(CC4)C
- InChIKey
- JVDOKQYTTYUYDV-UHFFFAOYSA-N
- InChI
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- Synonyms
- NCGC00262608-02 | AC-24600 | N-(tert-Butyl)-3-((5-methyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)am...
- WHI-P180● In Stock — US warehouse, ships to EU* Item #: W336667View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC
- InChIKey
- BNDYIYYKEIXHNK-UHFFFAOYSA-N
- InChI
- 1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-4-3-5-11(20)6-10/h3-9,20H,1-2H3,(H,17,18,19)
- Synonyms
- DB03365 | AKOS002350928 | BDBM4622 | WHI-P180(Janex 3) | DTXSID50943478 | s6520 | Phenol, 3-[(6,7-dimethoxy-4-quinazo...
- lenvatinib Mesylate, Vascular endothelial growth factor receptor inhibitorCAS: 857890-39-2 EC Number: 812-398-0 PubChem CID: 11237762 Formula: C21H19N4O4Cl.CH4O3S Molecular Weight: 522.96Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: M304782View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide;methanesulfonic acid
- SMILES
- COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl.CS(=O)(=O)O
- InChIKey
- HWLFIUUAYLEFCT-UHFFFAOYSA-N
- InChI
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- Synonyms
- DTXCID90157572 | CCG-269873 | 3-(2-aminoethyl) pyridine | AC-30100 | BCP11858 | DS-19245 | SB16581 | 6-carbamoyl-4-(3...
- 4-Aminopyrazolo[3,4-d]pyrimidine● In Stock — US warehouse, ships to EU* Item #: A151533View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1H-pyrazolo[3,4-d]pyrimidin-4-amine
- SMILES
- C1=NNC2=NC=NC(=C21)N
- InChIKey
- LHCPRYRLDOSKHK-UHFFFAOYSA-N
- InChI
- 1S/C5H5N5/c6-4-3-1-9-10-5(3)8-2-7-4/h1-2H,(H3,6,7,8,9,10)
- Synonyms
- (4S-(4alpha,4aalpha,8abeta))-Octahydro-4,8a-dimethyl-4a(2H)-naphthol | 4-Amino-1H-pyrazolo[3,4-D]pyrimidine | 4-Amino...
- WHI-P180 Hydrochloride● In Stock — US warehouse, ships to EU* Item #: W404124View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol;hydrochloride
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC.Cl
- InChIKey
- MJLLZROGIFJFJJ-UHFFFAOYSA-N
- InChI
- 1S/C16H15N3O3.ClH/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-4-3-5-11(20)6-10;/h3-9,20H,1-2H3,(H,17,18,19);1H
- Synonyms
- 3-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol Hydrochloride | 3-[(6,7-Dimethoxyquinazolin-4-yl)amino]phenol Hydrochlo...
![4-Aminopyrazolo[3,4-d]pyrimidine](https://www.aladdinsci.com/media/catalog/product/cache/6360e336b2a70951114dbd37294096ee/A/1/A151533.png)
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
Which compounds are listed for RET?
Compounds associated with RET are grouped here under the Protein Tyrosine Kinase/RTK classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does RET sit within Protein Tyrosine Kinase/RTK?
RET is one target listing within the Protein Tyrosine Kinase/RTK classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from RET?
For compounds listed under RET, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for RET?
Browse the parent Protein Tyrosine Kinase/RTK listing to reach targets neighbouring RET, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.