SHMT

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  1. SHIN 1
    CAS: 2146095-85-2 PubChem CID: 134335083 Formula: C24H24N4O2 Molecular Weight: 400.48
    ● In Stock — US warehouse, ships to EU* Item #: S288641
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    IUPAC Name
    6-amino-4-[3-(hydroxymethyl)-5-phenylphenyl]-3-methyl-4-propan-2-yl-2H-pyrano[2,3-c]pyrazole-5-carbonitrile
    SMILES
    CC1=C2C(=NN1)OC(=C(C2(C3=CC(=CC(=C3)C4=CC=CC=C4)CO)C(C)C)C#N)N
    InChIKey
    VVVOFJZXKJKHTD-UHFFFAOYSA-N
    InChI
    1S/C24H24N4O2/c1-14(2)24(20(12-25)22(26)30-23-21(24)15(3)27-28-23)19-10-16(13-29)9-18(11-19)17-7-5-4-6-8-17/h4-11,14,29H,13,26H2,1-3H3,(H,27,28)
    Synonyms
    6-Amino-1,4-dihydro-4-[5-(hydroxymethyl)[1,1'-biphenyl]-3-yl]-3-methyl-4-(1-methylethyl)pyrano[2,3-c]pyrazole-5-carbo...
  2. (+)-SHIN1
    CAS: 2443966-90-1 PubChem CID: 134335071 Formula: C24H24N4O2 Molecular Weight: 400.47
    ◐ .Made to order · 8–12 wks Item #: S649190
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    IUPAC Name
    (4S)-6-amino-4-[3-(hydroxymethyl)-5-phenylphenyl]-3-methyl-4-propan-2-yl-2H-pyrano[2,3-c]pyrazole-5-carbonitrile
    SMILES
    CC1=C2C(=NN1)OC(=C(C2(C3=CC(=CC(=C3)C4=CC=CC=C4)CO)C(C)C)C#N)N
    InChIKey
    VVVOFJZXKJKHTD-DEOSSOPVSA-N
    InChI
    1S/C24H24N4O2/c1-14(2)24(20(12-25)22(26)30-23-21(24)15(3)27-28-23)19-10-16(13-29)9-18(11-19)17-7-5-4-6-8-17/h4-11,14,29H,13,26H2,1-3H3,(H,27,28)/t24-/show more
  3. SHMT-IN-3
    CAS: 330638-43-2 PubChem CID: 2712855
    ◐ .Made to order · 8–12 wks Item #: S1443690
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    IUPAC Name
    4-[4-[2-[4-(3-carboxypropanoylamino)phenyl]pyrimidin-4-yl]anilino]-4-oxobutanoic acid
    SMILES
    C1=CC(=CC=C1C2=NC(=NC=C2)C3=CC=C(C=C3)NC(=O)CCC(=O)O)NC(=O)CCC(=O)O
    InChIKey
    LZRQXDAEFLBXCL-UHFFFAOYSA-N
    InChI
    1S/C24H22N4O6/c29-20(9-11-22(31)32)26-17-5-1-15(2-6-17)19-13-14-25-24(28-19)16-3-7-18(8-4-16)27-21(30)10-12-23(33)34/h1-8,13-14H,9-12H2,(H,26,29)(H,27show more
  4. SHMT-IN-2
    CAS: 2102681-49-0 PubChem CID: 134335070
    ◐ .Made to order · 8–12 wks Item #: S1443694
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    IUPAC Name
    6-amino-3-methyl-4-propan-2-yl-4-[3-pyrrolidin-1-yl-5-(trifluoromethyl)phenyl]-2H-pyrano[2,3-c]pyrazole-5-carbonitrile
    SMILES
    CC1=C2C(=NN1)OC(=C(C2(C3=CC(=CC(=C3)N4CCCC4)C(F)(F)F)C(C)C)C#N)N
    InChIKey
    NOKJZHRLDAOFCV-UHFFFAOYSA-N
    InChI
    1S/C22H24F3N5O/c1-12(2)21(17(11-26)19(27)31-20-18(21)13(3)28-29-20)14-8-15(22(23,24)25)10-16(9-14)30-6-4-5-7-30/h8-10,12H,4-7,27H2,1-3H3,(H,28,29)
  5. (Rac)-SHIN2
    CAS: 2204289-53-0 Formula: C23H26N4O3 Molecular Weight: 406.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: R1496358
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  6. SHMT-IN-1
    CAS: 1508286-18-7 Formula: C18H16Cl2N4O Molecular Weight: 375.25
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: S1495997
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  7. SHIN1
    CAS: 2146095-85-2 PubChem CID: 134335083 Formula: C24H24N4O2 Molecular Weight: 400.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Made to order · 8–12 wks Item #: S1494575
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

What can I find under SHMT?
This listing collects compounds associated with SHMT within our Metabolic Enzyme/Protease area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for SHMT?
Consider the reported potency of each SHMT compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for SHMT compounds?
Each SHMT product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search SHMT compounds by activity or structure?
Yes. Filter the SHMT listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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