Sigma Receptor

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  1. PB 28 dihydrochloride
    CAS: 172907-03-8 EC Number: 633-988-2 Formula: C24H40Cl2N2O Molecular Weight: 443.49
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: P286937
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    SMILES
    O=C1C=C(C)C(/C(C)=N/C2=C(N)C=CC=C2)=C(O)N1O.Cl.Cl
    InChIKey
    DSRBJOQIBXACIV-UHFFFAOYSA-N
    Synonyms
    HY-108511 | BP177452 | PB28 dihydrochloride, >=98% (HPLC), solid | EC-000.2424 | J-010863 | PB28 (dihydrochloride) | ...
  2. SKF 83959 hydrobromide
    CAS: 67287-95-0 Formula: C18H21BrClNO2 Molecular Weight: 398.73
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: S288574
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    IUPAC Name
    9-chloro-3-methyl-5-(3-methylphenyl)-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol;hydrobromide
    SMILES
    CC1=CC(=CC=C1)C2CN(CCC3=C(C(=C(C=C23)O)O)Cl)C.Br
    InChIKey
    FHYWNBUFNGHNCP-UHFFFAOYSA-N
    InChI
    1S/C18H20ClNO2.BrH/c1-11-4-3-5-12(8-11)15-10-20(2)7-6-13-14(15)9-16(21)18(22)17(13)19;/h3-5,8-9,15,21-22H,6-7,10H2,1-2H3;1H
    Synonyms
    EU-0101067 | MLS002153381 | SR-01000076126-2 | 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-m...
  3. NE 100 hydrochloride
    CAS: 149409-57-4 Formula: C23H33NO2•HCl Molecular Weight: 391.97
    ● In Stock — US warehouse, ships to EU* Item #: N286812
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    IUPAC Name
    N-[2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl]-N-propylpropan-1-amine;hydrochloride
    SMILES
    CCCN(CCC)CCC1=CC(=C(C=C1)OC)OCCC2=CC=CC=C2.Cl
    InChIKey
    ZHGMDXSHODHWHV-UHFFFAOYSA-N
    InChI
    1S/C23H33NO2.ClH/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20;/h6-12,19H,4-5,13-18H2,1-3H3;1H
    Synonyms
    NE-100 (hydrochloride) | 4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanamine hydrochloride | NE100 HCl | NE-10...
  4. PRE-084, Agonist of sigma non-opioid intracellular receptor 1
    CAS: 138847-85-5 Formula: C19H27NO3 Molecular Weight: 317.42
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: P288761
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    IUPAC Name
    2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate
    SMILES
    C1CCC(CC1)(C2=CC=CC=C2)C(=O)OCCN3CCOCC3
    InChIKey
    RQHKZUBCUZVZEF-UHFFFAOYSA-N
    InChI
    1S/C19H27NO3/c21-18(23-16-13-20-11-14-22-15-12-20)19(9-5-2-6-10-19)17-7-3-1-4-8-17/h1,3-4,7-8H,2,5-6,9-16H2
    Synonyms
    BRD-K57304726-003-03-6 | 2-(6-(Ethyl(2-hydroxypropyl)amino)-3-pyridazinyl)-hydrazinecarboxylic acid ethyl ester | CHE...
  5. Pentoxyverine Citrate, Sigma opioid receptor agonist
    CAS: 23142-01-0 EC Number: 245-449-5 Formula: C20H31NO3·C6H8O7 Molecular Weight: 525.59
    ● In Stock — US warehouse, ships to EU* Item #: P129500
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    IUPAC Name
    2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid
    SMILES
    CCN(CC)CCOCCOC(=O)C1(CCCC1)C2=CC=CC=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
    InChIKey
    AKJDEXBCRLOVTH-UHFFFAOYSA-N
    InChI
    1S/C20H31NO3.C6H8O7/c1-3-21(4-2)14-15-23-16-17-24-19(22)20(12-8-9-13-20)18-10-6-5-7-11-18;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-7,10-11H,3-4,8-9,12-17H2,1-show more
    Synonyms
    AKOS015899622 | NCGC00093760-01 | (E)-3,7-Dimethyl-2,6-octadienenitrile | A839013 | HMS2096M15 | Prestwick_748 | Tocl...
  6. Siramesine hydrochloride
    CAS: 224177-60-0 PubChem CID: 9891778 Formula: C30H31FN2O.HCl Molecular Weight: 491.04
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S288444
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    IUPAC Name
    1'-[4-[1-(4-fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4'-piperidine];hydrochloride
    SMILES
    C1CN(CCC12C3=CC=CC=C3CO2)CCCCC4=CN(C5=CC=CC=C54)C6=CC=C(C=C6)F.Cl
    InChIKey
    ILSRGIFRZZSGPN-UHFFFAOYSA-N
    InChI
    1S/C30H31FN2O.ClH/c31-25-12-14-26(15-13-25)33-21-23(27-9-2-4-11-29(27)33)7-5-6-18-32-19-16-30(17-20-32)28-10-3-1-8-24(28)22-34-30;/h1-4,8-15,21H,5-7,1show more
    Synonyms
    Lu 28-179;Lu-28-179;Lu 28-179 hydrochloride | 1'-(4-(1-(4-Fluorophenyl)-1H-indol-3-yl)butyl)-3H-spiro[isobenzofuran-1...
  7. Rimcazole dihydrochloride
    CAS: 75859-03-9 PubChem CID: 53388 Formula: C21H27N3•2HCl Molecular Weight: 394.39
    ● In Stock — US warehouse, ships to EU* Item #: R286742
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    IUPAC Name
    9-[3-[(3S,5R)-3,5-dimethylpiperazin-1-yl]propyl]carbazole;dihydrochloride
    SMILES
    CC1CN(CC(N1)C)CCCN2C3=CC=CC=C3C4=CC=CC=C42.Cl.Cl
    InChIKey
    ZWHRZGHGYMUSRM-VWDRLOGHSA-N
    InChI
    1S/C21H27N3.2ClH/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24;;/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3;2*1H/t16-,17+;;
    Synonyms
    Rimcazole hydrochloride (USAN) | Rimcazole HCl | Rimcazole hydrochloride [USAN] | AKOS024456636 | DTXCID7025681 | SR-...
  8. PD 144418 oxalate
    CAS: 1794760-28-3 PubChem CID: 53447361 Formula: C20H24N2O5 Molecular Weight: 372.42
    ● In Stock — US warehouse, ships to EU* Item #: P287580
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    IUPAC Name
    3-(4-methylphenyl)-5-(1-propyl-3,6-dihydro-2H-pyridin-5-yl)-1,2-oxazole;oxalic acid
    SMILES
    CCCN1CCC=C(C1)C2=CC(=NO2)C3=CC=C(C=C3)C.C(=O)(C(=O)O)O
    InChIKey
    IWSFHSVGBKPYFN-UHFFFAOYSA-N
    InChI
    1S/C18H22N2O.C2H2O4/c1-3-10-20-11-4-5-16(13-20)18-12-17(19-21-18)15-8-6-14(2)7-9-15;3-1(4)2(5)6/h5-9,12H,3-4,10-11,13H2,1-2H3;(H,3,4)(H,5,6)
    Synonyms
    1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE | BP177453 | J-009071 | SCHEMBL466958...
  9. BD 1008 dihydrobromide
    CAS: 138356-09-9 Formula: C15H24Br2Cl2N2 Molecular Weight: 463.08
    ◐ .Made to order · 8–12 wks Item #: B275588
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    IUPAC Name
    2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylethyl)ethanamine;dihydrobromide
    SMILES
    CN(CCC1=CC(=C(C=C1)Cl)Cl)CCN2CCCC2.Br.Br
    InChIKey
    YTBUMHOSKIAYCZ-UHFFFAOYSA-N
    InChI
    1S/C15H22Cl2N2.2BrH/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13;;/h4-5,12H,2-3,6-11H2,1H3;2*1H
    Synonyms
    N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-1-pyrrolidineethanaminedihydrobromide
  10. AN2/AVex-73 hydrochloride salt
    CAS: 195615-84-0 Formula: C19H24ClNO Molecular Weight: 317.86
    ● In Stock — US warehouse, ships to EU* Item #: A175437
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    IUPAC Name
    1-(2,2-diphenyloxolan-3-yl)-N,N-dimethylmethanamine;hydrochloride
    SMILES
    CN(C)CC1CCOC1(C2=CC=CC=C2)C3=CC=CC=C3.Cl
    InChIKey
    FEQOLYDPQKHFTD-UHFFFAOYSA-N
    InChI
    1S/C19H23NO.ClH/c1-20(2)15-18-13-14-21-19(18,16-9-5-3-6-10-16)17-11-7-4-8-12-17;/h3-12,18H,13-15H2,1-2H3;1H
    Synonyms
    AVex-73 hydrochloride | (+/-)-.DELTA.-HEXALACTONE | Blarcamesine hydrochloride [USAN] | AC-33187 | MFCD30146449 | SCH...
  11. Siramesine fumarate salt
    CAS: 163630-79-3 PubChem CID: 9829525 Formula: C34H35FN2O5 Molecular Weight: 570.65
    ◐ .Made to order · 8–12 wks Item #: S167736
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    IUPAC Name
    (E)-but-2-enedioic acid;1'-[4-[1-(4-fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4'-piperidine]
    SMILES
    C1CN(CCC12C3=CC=CC=C3CO2)CCCCC4=CN(C5=CC=CC=C54)C6=CC=C(C=C6)F.C(=CC(=O)O)C(=O)O
    InChIKey
    VONJQLKJOYOVBE-WLHGVMLRSA-N
    InChI
    1S/C30H31FN2O.C4H4O4/c31-25-12-14-26(15-13-25)33-21-23(27-9-2-4-11-29(27)33)7-5-6-18-32-19-16-30(17-20-32)28-10-3-1-8-24(28)22-34-30;5-3(6)1-2-4(7)8/hshow more
    Synonyms
    1′-[4-[1-(4-Fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4′-piperidine] fumarate salt,Lu 28-179
  12. Oxeladin citrate
    CAS: 52432-72-1 Formula: C26H41NO10 Molecular Weight: 527.6
    ● In Stock — US warehouse, ships to EU* Item #: O303887
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    IUPAC Name
    2-[2-(diethylamino)ethoxy]ethyl 2-ethyl-2-phenylbutanoate;2-hydroxypropane-1,2,3-tricarboxylic acid
    SMILES
    CCC(CC)(C1=CC=CC=C1)C(=O)OCCOCCN(CC)CC.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
    InChIKey
    KVKJFNUGVOFNGU-UHFFFAOYSA-N
    InChI
    1S/C20H33NO3.C6H8O7/c1-5-20(6-2,18-12-10-9-11-13-18)19(22)24-17-16-23-15-14-21(7-3)8-4;7-3(8)1-6(13,5(11)12)2-4(9)10/h9-13H,5-8,14-17H2,1-4H3;13H,1-2Hshow more
    Synonyms
    2-(2-(Diethylamino)ethoxy)ethyl 2-ethyl-2-phenylbutanoate 2-hydroxypropane-1,2,3-tricarboxylate | DTXCID2026608 | Tox...
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Frequently Asked Questions

What can I find under Sigma Receptor?
This listing collects compounds associated with Sigma Receptor within our Neuronal Signaling area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Sigma Receptor?
Consider the reported potency of each Sigma Receptor compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Sigma Receptor compounds?
Each Sigma Receptor product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Sigma Receptor compounds by activity or structure?
Yes. Filter the Sigma Receptor listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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