Sodium Channel

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  1. PF-05089771 (tosylate)
    CAS: 1430806-04-4 PubChem CID: 71554187 Formula: C18H12Cl2FN5O3S2•C7H8O3S Molecular Weight: 672.56
    Solid ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: P287496
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    IUPAC Name
    4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide;4-methylbenzenesulfonic acid
    SMILES
    CC1=CC=C(C=C1)S(=O)(=O)O.C1=CC(=C(C=C1Cl)C2=C(NN=C2)N)OC3=CC(=C(C=C3Cl)S(=O)(=O)NC4=CSC=N4)F
    InChIKey
    NVKBPDYKPNYMDR-UHFFFAOYSA-N
    InChI
    1S/C18H12Cl2FN5O3S2.C7H8O3S/c19-9-1-2-14(10(3-9)11-6-24-25-18(11)22)29-15-5-13(21)16(4-12(15)20)31(27,28)26-17-7-30-8-23-17;1-6-2-4-7(5-3-6)11(8,9)10/show more
    Synonyms
    1430806-04-4 | SCHEMBL14880153 | AKOS027470316 | NVKBPDYKPNYMDR-UHFFFAOYSA-N | UNII-NG8E748OWS | 4-[2-(5-amino-1H-pyr...
  2. Zonisamide-d4
    CAS: 1020720-04-0 PubChem CID: 45040707 Formula: C8H4D4N2O3S Molecular Weight: 216.25
    ● In Stock — US warehouse, ships to EU* Item #: Z334653
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    IUPAC Name
    (4,5,6,7-tetradeuterio-1,2-benzoxazol-3-yl)methanesulfonamide
    SMILES
    C1=CC=C2C(=C1)C(=NO2)CS(=O)(=O)N
    InChIKey
    UBQNRHZMVUUOMG-RHQRLBAQSA-N
    InChI
    1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)/i1D,2D,3D,4D
    Synonyms
    1-[(~2~H_4_)-1,2-Benzoxazol-3-yl]methanesulfonamide | 3-(Sulfamoylmethyl)-1,2-benzisoxazole-d4 | 1020720-04-0 | 1,2-B...
  3. Lidocaine hydrochloride
    CAS: 73-78-9 Formula: C14H22N2O.HCl Molecular Weight: 270.8
    ● In Stock — US warehouse, ships to EU* Item #: L276132
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    IUPAC Name
    2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrochloride
    SMILES
    CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.Cl
    InChIKey
    IYBQHJMYDGVZRY-UHFFFAOYSA-N
    InChI
    1S/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H
    Synonyms
    Rucaina hydrochloride | Xilina hydrochloride | Xyloneural | Lidocaine hydrochloride | Lidothesin | Xycaine hydrochlor...
  4. NAV 26
    CAS: 1198160-14-3 Formula: C22H21F3N2O4 Molecular Weight: 434.41
    ● In Stock — US warehouse, ships to EU* Item #: N287524
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    IUPAC Name
    2-(oxan-4-yl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
    SMILES
    C1COCCC1N2C(C3=CC=CC=C3C2=O)C(=O)NCC4=CC=C(C=C4)OC(F)(F)F
    InChIKey
    ICGMZCVSHDKQTE-UHFFFAOYSA-N
    InChI
    1S/C22H21F3N2O4/c23-22(24,25)31-16-7-5-14(6-8-16)13-26-20(28)19-17-3-1-2-4-18(17)21(29)27(19)15-9-11-30-12-10-15/h1-8,15,19H,9-13H2,(H,26,28)
    Synonyms
    2,3-Dihydro-3-oxo-2-(tetrahydro-2H-pyran-4-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
  5. PF 04885614, Inhibitor of K v11.1;Inhibitor of Na v1.6;Inhibitor of Na v1.8
    CAS: 1480833-70-2 PubChem CID: 65459349 Formula: C13H14F3N3O Molecular Weight: 285.26
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: P288823
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    IUPAC Name
    2-[5-[4-(trifluoromethoxy)phenyl]-1H-imidazol-2-yl]propan-2-amine
    SMILES
    CC(C)(C1=NC=C(N1)C2=CC=C(C=C2)OC(F)(F)F)N
    InChIKey
    AGORGFNWYAUYSU-UHFFFAOYSA-N
    InChI
    1S/C13H14F3N3O/c1-12(2,17)11-18-7-10(19-11)8-3-5-9(6-4-8)20-13(14,15)16/h3-7H,17H2,1-2H3,(H,18,19)
    Synonyms
    1-Methyl-[1-[4-(4-trifluoromethoxy)phenyl]-imidazol-2-yl]-ethanamine
  6. Huwentoxin IV
    CAS: 526224-73-7 PubChem CID: 90488968 Formula: C₁₇₄H₂₇₈N₅₂O₅₁S₆ Molecular Weight: 4106.79
    ◐ .Made to order · 8–12 wks Item #: H287997
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    IUPAC Name
    4-amino-5-[[30-[[6-amino-1-[[1-[[5-amino-1-[(1-amino-3-methyl-1-oxopentan-2-yl)amino]-1,5-dioxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-ylshow more
    SMILES
    CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC2CSSCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N1)CCC(show more
    InChIKey
    MJMLBAPXMAOKDU-UHFFFAOYSA-N
    InChI
    1S/C174H278N52O51S6/c1-13-87(9)135(138(185)243)223-149(254)106(51-54-128(182)234)201-152(257)110(68-92-45-47-94(232)48-46-92)206-144(249)100(39-22-27-show more
  7. Flecainide-d3
    CAS: 127413-31-4 Formula: C17H17D3F6N2O3 Molecular Weight: 417.36
    ◐ .Made to order · 8–12 wks Item #: F342768
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    IUPAC Name
    2,4,5-trideuterio-N-(piperidin-2-ylmethyl)-3,6-bis(2,2,2-trifluoroethoxy)benzamide
    SMILES
    C1CCNC(C1)CNC(=O)C2=C(C=CC(=C2)OCC(F)(F)F)OCC(F)(F)F
    InChIKey
    DJBNUMBKLMJRSA-JZLVSFENSA-N
    InChI
    1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)/i4D,5D,7D
    Synonyms
    HY-W010950S | AKOS030243259 | DTXSID40675897 | N-(Piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide-d3 | ...
  8. Disopyramide phosphate salt, Sodium channel alpha subunit blocker
    CAS: 22059-60-5 EC Number: 244-756-1 Formula: C21H32N3O5P Molecular Weight: 437.47
    ● In Stock — US warehouse, ships to EU* Item #: D332029
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    IUPAC Name
    4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide;phosphoric acid
    SMILES
    CC(C)N(CCC(C1=CC=CC=C1)(C2=CC=CC=N2)C(=O)N)C(C)C.OP(=O)(O)O
    InChIKey
    CGDDQFMPGMYYQP-UHFFFAOYSA-N
    InChI
    1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2show more
    Synonyms
    Disopyramide (phosphate) | Disopyramide phosphate (JAN/USP) | DISOPYRAMIDE PHOSPHATE [WHO-DD] | HMS3652M20 | LP00411 ...
  9. Jingzhaotoxin III, Gating inhibitor of K v2.1;Gating inhibitor of Na v1.5
    CAS: 925463-91-8 PubChem CID: 90488988 Formula: C174H241N47O46S6 Molecular Weight: 3919.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Made to order · 8–12 wks Item #: J288925
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    IUPAC Name
    1-[2-[[4-carboxy-2-[[3-methyl-2-[2-[[13,48,66,92-tetrakis(4-aminobutyl)-74-[[2-[[2-[(2-amino-3-carboxypropanoyl)amino]acetyl]amino]-4-carboxybutanoyl]show more
    SMILES
    CC1C(=O)NC2CSSCC3C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(CSSCC(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CO)CCCCN)C(Cshow more
    InChIKey
    OKELXNUZHJLTAQ-UHFFFAOYSA-N
    InChI
    1S/C174H241N47O46S6/c1-89(2)143(168(261)206-115(53-55-141(234)235)153(246)196-92(5)170(263)221-63-29-47-132(221)173(266)267)217-146(239)91(4)195-163(2show more
  10. Indoxacarb Solution in Acetonitrile
    CAS: 144171-61-9 EC Number: 604-398-2 Formula: C22H17ClF3N3O7 Molecular Weight: 527.83
    100μg/mL in Acetonitrile, uncertainty 3%
    ◐ .Made to order · 8–12 wks Item #: BWY396906
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    Technical Identifiers
    IUPAC Name
    methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate
    SMILES
    COC(=O)C12CC3=C(C1=NN(CO2)C(=O)N(C4=CC=C(C=C4)OC(F)(F)F)C(=O)OC)C=CC(=C3)Cl
    InChIKey
    VBCVPMMZEGZULK-UHFFFAOYSA-N
    InChI
    1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,1-2H3
    Synonyms
    HY-B0834 | Tox21_303872 | INDOXACARB, (R,S)- | methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamo...
  11. Indoxacarb Solution in Methanol
    CAS: 144171-61-9 EC Number: 604-398-2 Formula: C22H17ClF3N3O7 Molecular Weight: 527.83
    100μg/mL in Methanol, uncertainty 3%
    ◐ .Made to order · 8–12 wks Item #: BWY396902
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    Technical Identifiers
    IUPAC Name
    methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate
    SMILES
    COC(=O)C12CC3=C(C1=NN(CO2)C(=O)N(C4=CC=C(C=C4)OC(F)(F)F)C(=O)OC)C=CC(=C3)Cl
    InChIKey
    VBCVPMMZEGZULK-UHFFFAOYSA-N
    InChI
    1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,1-2H3
    Synonyms
    HY-B0834 | Tox21_303872 | INDOXACARB, (R,S)- | methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamo...
  12. Indoxacarb Solution in Acetonitrile
    CAS: 144171-61-9 Formula: C22H17ClF3N3O7 Molecular Weight: 527.83
    1000μg/mL in Acetonitrile, uncertainty 2%
    ◐ .Made to order · 8–12 wks Item #: BWY396904
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    Technical Identifiers
    IUPAC Name
    methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate
    SMILES
    COC(=O)C12CC3=C(C1=NN(CO2)C(=O)N(C4=CC=C(C=C4)OC(F)(F)F)C(=O)OC)C=CC(=C3)Cl
    InChIKey
    VBCVPMMZEGZULK-UHFFFAOYSA-N
    InChI
    1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,1-2H3
    Synonyms
    HY-B0834 | Tox21_303872 | INDOXACARB, (R,S)- | methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamo...
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Frequently Asked Questions

What can I find under Sodium Channel?
This listing collects compounds associated with Sodium Channel within our Membrane Transporter/Ion Channel area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Sodium Channel?
Consider the reported potency of each Sodium Channel compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Sodium Channel compounds?
Each Sodium Channel product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Sodium Channel compounds by activity or structure?
Yes. Filter the Sodium Channel listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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