TGF-β Receptor

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  1. LY2157299, TGF-beta receptor type I inhibitor
    CAS: 700874-72-2 EC Number: 142-220-0 Formula: C22H19N5O Molecular Weight: 369.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: L126937
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    IUPAC Name
    4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide
    SMILES
    CC1=NC(=CC=C1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N
    InChIKey
    IVRXNBXKWIJUQB-UHFFFAOYSA-N
    InChI
    1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28)
    Synonyms
    BDBM50015640 | 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]quinoline-6-carboxamide | MFCD00...
  2. LY2109761, Inhibitor of transforming growth factor beta receptor 1;Inhibitor of transforming growth factor beta receptor 2
    CAS: 700874-71-1 Formula: C26H27N5O2 Molecular Weight: 441.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: L126135
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    IUPAC Name
    4-[2-[4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl]oxyethyl]morpholine
    SMILES
    C1CC2=C(C(=NN2C1)C3=CC=CC=N3)C4=C5C=CC(=CC5=NC=C4)OCCN6CCOCC6
    InChIKey
    IHLVSLOZUHKNMQ-UHFFFAOYSA-N
    InChI
    1S/C26H27N5O2/c1-2-9-27-22(4-1)26-25(24-5-3-11-31(24)29-26)21-8-10-28-23-18-19(6-7-20(21)23)33-17-14-30-12-15-32-16-13-30/h1-2,4,6-10,18H,3,5,11-17H2
    Synonyms
    HMS3674E17 | SB19481 | AKOS022183732 | GTPL8075 | BCP9000868 | LY 2109761 | Q27082613 | .ALPHA.-KETOGLUCONIC ACID | Q...
  3. Melamine
    CAS: 108-78-1 EC Number: 203-615-4 Formula: C3H6N6 Molecular Weight: 126.12
    ● In Stock — Germany Item #: M108433
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    IUPAC Name
    1,3,5-triazine-2,4,6-triamine
    SMILES
    C1(=NC(=NC(=N1)N)N)N
    InChIKey
    JDSHMPZPIAZGSV-UHFFFAOYSA-N
    InChI
    1S/C3H6N6/c4-1-7-2(5)9-3(6)8-1/h(H6,4,5,6,7,8,9)
    Synonyms
    Triaminotriazine | s-Triazinetriamine | Pluragard | Cyanuric triamide | Yukamelamine | Hicophor PR | Cyanurotriamine ...
  4. SB-505124 hydrochloride
    CAS: 356559-13-2 PubChem CID: 16079009 Formula: C20H21N3O2HCl Molecular Weight: 371.86
    ● In Stock — US warehouse, ships to EU* Item #: T334804
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    IUPAC Name
    2-[4-(1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine;hydrochloride
    SMILES
    CC1=NC(=CC=C1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4.Cl
    InChIKey
    BTUOOXPZOVNPMF-UHFFFAOYSA-N
    InChI
    1S/C20H21N3O2.ClH/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2,3)4)13-8-9-15-16(10-13)25-11-24-15;/h5-10H,11H2,1-4H3,(H,22,23);1H
    Synonyms
    2-(5-benzo[1,3]dioxol-5-yl-2-tert-butyl-3h-imidazol-4-yl)-6-methylpyridine hydrochloride | BCP19172 | SCHEMBL140197 |...
  5. NCX 466
    CAS: 1262956-64-8 PubChem CID: 49855334 Formula: C20H24N2O9 Molecular Weight: 436.41
    ◐ .Made to order · 8–12 wks Item #: N288651
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    IUPAC Name
    [(5S)-5,6-dinitrooxyhexyl] (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
    SMILES
    CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OCCCCC(CO[N+](=O)[O-])O[N+](=O)[O-]
    InChIKey
    QTUSNUCZIUBIBF-LIRRHRJNSA-N
    InChI
    1S/C20H24N2O9/c1-14(15-6-7-17-12-18(28-2)9-8-16(17)11-15)20(23)29-10-4-3-5-19(31-22(26)27)13-30-21(24)25/h6-9,11-12,14,19H,3-5,10,13H2,1-2H3/t14-,19-/show more
    Synonyms
    (αS)-6-Methoxy-α-methyl-2-naphthaleneacetic acid (5S)-5,6-bis(nitrooxy)hexyl ester | (S)-(S)-5,6-bis(nitrooxy)hexyl 2...
  6. SM 16
    CAS: 614749-78-9 PubChem CID: 10387982 Formula: C25H26N4O3 Molecular Weight: 430.5
    ◐ .Made to order · 8–12 wks Item #: S287888
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    IUPAC Name
    4-[4-(1,3-benzodioxol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl]bicyclo[2.2.2]octane-1-carboxamide
    SMILES
    CC1=NC(=CC=C1)C2=C(N=C(N2)C34CCC(CC3)(CC4)C(=O)N)C5=CC6=C(C=C5)OCO6
    InChIKey
    JUHTXZGCTPDXRU-UHFFFAOYSA-N
    InChI
    1S/C25H26N4O3/c1-15-3-2-4-17(27-15)21-20(16-5-6-18-19(13-16)32-14-31-18)28-23(29-21)25-10-7-24(8-11-25,9-12-25)22(26)30/h2-6,13H,7-12,14H2,1H3,(H2,26,show more
    Synonyms
    4-[4-(1,3-Benzodioxol-5-yl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-2-yl]bicyclo[2.2.2]octane-1-carboxamide
  7. GW788388
    CAS: 452342-67-5 Formula: C25H23N5O2 Molecular Weight: 425.48
    ● In Stock — US warehouse, ships to EU* Item #: G125999
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    IUPAC Name
    N-(oxan-4-yl)-4-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]benzamide
    SMILES
    C1COCCC1NC(=O)C2=CC=C(C=C2)C3=NC=CC(=C3)C4=C(NN=C4)C5=CC=CC=N5
    InChIKey
    SAGZIBJAQGBRQA-UHFFFAOYSA-N
    InChI
    1S/C25H23N5O2/c31-25(29-20-9-13-32-14-10-20)18-6-4-17(5-7-18)23-15-19(8-12-27-23)21-16-28-30-24(21)22-3-1-2-11-26-22/h1-8,11-12,15-16,20H,9-10,13-14H2show more
    Synonyms
    FT-0700309 | HMS3656N21 | UNII-N14114957J | Q27284368 | N-(oxan-4-yl)-4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-...
  8. RepSox
    CAS: 446859-33-2 EC Number: 663-924-9 Formula: C17H13N5 Molecular Weight: 287.32
    ● In Stock — US warehouse, ships to EU* Item #: R125531
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    IUPAC Name
    2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
    SMILES
    CC1=NC(=CC=C1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4
    InChIKey
    LBPKYPYHDKKRFS-UHFFFAOYSA-N
    InChI
    1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)
    Synonyms
    ALK5 Inhibitor II | 2-(3-(6-methyl-2-pyridinyl)-1h-pyrazol-4-yl)-1,5-naphthyridine | DTXSID80332295 | AKOS016009677 |...
  9. Neuropathiazol
    CAS: 880090-88-0 Formula: C19H18N2O2S Molecular Weight: 338.42
    ● In Stock — US warehouse, ships to EU* Item #: N287361
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    IUPAC Name
    ethyl 4-[methyl-(2-phenyl-1,3-thiazol-4-yl)amino]benzoate
    SMILES
    CCOC(=O)C1=CC=C(C=C1)N(C)C2=CSC(=N2)C3=CC=CC=C3
    InChIKey
    MGKYEWWFHSESJN-UHFFFAOYSA-N
    InChI
    1S/C19H18N2O2S/c1-3-23-19(22)15-9-11-16(12-10-15)21(2)17-13-24-18(20-17)14-7-5-4-6-8-14/h4-13H,3H2,1-2H3
    Synonyms
    AKOS015919526 | BCPP000150 | Ethyl 4-(methyl(2-phenylthiazol-4-yl)amino)benzoate;Neuropathiazol | SCHEMBL8238620 | BC...
  10. SB431542, Inhibitor of activin A receptor type 1C;Inhibitor of transforming growth factor beta receptor 1
    CAS: 301836-41-9 EC Number: 188-365-3 Formula: C22H16N4O3 Molecular Weight: 384.39
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S125924
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    IUPAC Name
    4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
    SMILES
    C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
    InChIKey
    FHYUGAJXYORMHI-UHFFFAOYSA-N
    InChI
    1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
    Synonyms
    4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide | 4-[4-(1,3-BENZODIOXOL-5-YL)-5-(2-PYRIDI...
  11. SB505124, Inhibitor of transforming growth factor beta receptor 1
    CAS: 694433-59-5 PubChem CID: 9858940 Formula: C20H21N3O2 Molecular Weight: 335.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S126125
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    IUPAC Name
    2-[4-(1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine
    SMILES
    CC1=NC(=CC=C1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4
    InChIKey
    WGZOTBUYUFBEPZ-UHFFFAOYSA-N
    InChI
    1S/C20H21N3O2/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2,3)4)13-8-9-15-16(10-13)25-11-24-15/h5-10H,11H2,1-4H3,(H,22,23)
    Synonyms
    HMS3655F08 | SCHEMBL373422 | AS-74679 | amino-4,6-dimethoxypyrimidine | CCG-267861 | TGF-beta RI Inhibitor III | etho...
  12. SB525334
    CAS: 356559-20-1 EC Number: 636-855-7 PubChem CID: 9967941 Formula: C21H21N5 Molecular Weight: 343.42
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S129327
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    IUPAC Name
    6-[2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl]quinoxaline
    SMILES
    CC1=NC(=CC=C1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=NC=CN=C4C=C3
    InChIKey
    DKPQHFZUICCZHF-UHFFFAOYSA-N
    InChI
    1S/C21H21N5/c1-13-6-5-7-16(24-13)19-18(25-20(26-19)21(2,3)4)14-8-9-15-17(12-14)23-11-10-22-15/h5-12H,1-4H3,(H,25,26)
    Synonyms
    6-(2-(tert-Butyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline
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Frequently Asked Questions

What can I find under TGF-β Receptor?
This listing collects compounds associated with TGF-β Receptor within our TGF-beta/Smad area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for TGF-β Receptor?
Consider the reported potency of each TGF-β Receptor compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for TGF-β Receptor compounds?
Each TGF-β Receptor product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search TGF-β Receptor compounds by activity or structure?
Yes. Filter the TGF-β Receptor listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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