Thyroid Hormone Receptor

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  1. Thyroxine methyl ester
    CAS: 32180-11-3 PubChem CID: 13911218 Formula: C16H13I4NO4 Molecular Weight: 790.9
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: T275997
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    IUPAC Name
    methyl (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate
    SMILES
    COC(=O)C(CC1=CC(=C(C(=C1)I)OC2=CC(=C(C(=C2)I)O)I)I)N
    InChIKey
    ZTSGDCMQRKBJKC-ZDUSSCGKSA-N
    InChI
    1S/C16H13I4NO4/c1-24-16(23)13(21)4-7-2-11(19)15(12(20)3-7)25-8-5-9(17)14(22)10(18)6-8/h2-3,5-6,13,22H,4,21H2,1H3/t13-/m0/s1
    Synonyms
    (S)-Methyl 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate | SCHEMBL8369341 | Thyroxine Methyl...
  2. Levothyroxine sodium hydrate
    CAS: 25416-65-3 PubChem CID: 23667619 Formula: C15H10I4NNaO4·xH2O Molecular Weight: 798.86 (anhydrous basis)
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: L135598
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    IUPAC Name
    sodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;hydrate
    SMILES
    C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])N.O.[Na+]
    InChIKey
    ANMYAHDLKVNJJO-LTCKWSDVSA-M
    InChI
    1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0show more
    Synonyms
    3,3',5,5'-Tetraiodo-L-thyronine monosodium salt | E78443 | Q27107209 | Sodium (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodop...
  3. L-Thyroxine (T4), Agonist of Thyroid hormone receptor-α;Agonist of Thyroid hormone receptor-β
    CAS: 51-48-9 EC Number: 200-101-1 PubChem CID: 5819 Formula: C15H11I4NO4 Molecular Weight: 776.87
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: T106193
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    IUPAC Name
    (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
    SMILES
    C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)O)N
    InChIKey
    XUIIKFGFIJCVMT-LBPRGKRZSA-N
    InChI
    1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
    Synonyms
    T4 | DivK1c_006967 | L-Thyroxine, free acid | Spectrum_001076 | 2ceo | Eutirox | L Thyroxine | LEVOTHYROXINE (USP-RS)...
  4. 6-Propyl-2-thiouracil
    CAS: 51-52-5 EC Number: 200-103-2 Formula: C7H10N2OS Molecular Weight: 170.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P106338
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    IUPAC Name
    6-propyl-2-sulfanylidene-1H-pyrimidin-4-one
    SMILES
    CCCC1=CC(=O)NC(=S)N1
    InChIKey
    KNAHARQHSZJURB-UHFFFAOYSA-N
    InChI
    1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)
    Synonyms
    6-PTU | BSPBio_000387 | PROPYLTHIOURACIL [IARC] | PROPYLTHIOURACIL [EP MONOGRAPH] | Propylthiouracil; 2,3-dihydro-6-p...
  5. Levothyroxine sodium hydrate
    CAS: 25416-65-3 EC Number: 685-634-1 PubChem CID: 23667619 Formula: C15H10I4NNaO4·xH2O Molecular Weight: 798.86 (anhydrous basis)
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: T113354
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    IUPAC Name
    sodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;hydrate
    SMILES
    C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])N.O.[Na+]
    InChIKey
    ANMYAHDLKVNJJO-LTCKWSDVSA-M
    InChI
    1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0show more
    Synonyms
    Levothyroxine sodium | 3,3′,5,5′-Tetraiodo-L-thyronine monosodium salt hydrate, L-Thyroxin monosodium salt hydrate | ...
  6. Iopanoic Acid
    CAS: 96-83-3 EC Number: 202-539-9 Formula: C11H12I3NO2 Molecular Weight: 570.94
    Solid ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: I340871
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    IUPAC Name
    2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid
    SMILES
    CCC(CC1=C(C(=C(C=C1I)I)N)I)C(=O)O
    InChIKey
    OIRFJRBSRORBCM-UHFFFAOYSA-N
    InChI
    1S/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,2-3,15H2,1H3,(H,16,17)
    Synonyms
    HMS1922K20 | Iopanoic acid (USP:INN:BAN:JAN) | NINDS_000902 | OIRFJRBSRORBCM-UHFFFAOYSA- | IOPANOIC ACID [EP IMPURITY...
  7. Taltirelin, Thyrotropin-releasing hormone receptor agonist
    CAS: 103300-74-9 PubChem CID: 114750 Formula: C17H23N7O5 Molecular Weight: 405.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: T288583
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    IUPAC Name
    (4S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-1-methyl-2,6-dioxo-1,3-diazinane-4-carboxamide
    SMILES
    CN1C(=O)CC(NC1=O)C(=O)NC(CC2=CN=CN2)C(=O)N3CCCC3C(=O)N
    InChIKey
    LQZAIAZUDWIVPM-SRVKXCTJSA-N
    InChI
    1S/C17H23N7O5/c1-23-13(25)6-10(22-17(23)29)15(27)21-11(5-9-7-19-8-20-9)16(28)24-4-2-3-12(24)14(18)26/h7-8,10-12H,2-6H2,1H3,(H2,18,26)(H,19,20)(H,21,27show more
    Synonyms
    TALTIRELIN [MI] | CHEBI:135653 | GTPL2143 | Tox21_112682 | (S)-N-((S)-1-((S)-2-carbamoylpyrrolidin-1-yl)-3-(1H-imidaz...
  8. L-Thyroxine sodium salt pentahydrate
    CAS: 6106-07-6 PubChem CID: 23665037 Formula: C15H20I4NNaO9 Molecular Weight: 888.93
    ● In Stock — US warehouse, ships to EU* Item #: L274722
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    Technical Identifiers
    IUPAC Name
    sodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;pentahydrate
    SMILES
    C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])N.O.O.O.O.O.[Na+]
    InChIKey
    JMHCCAYJTTWMCX-QWPJCUCISA-M
    InChI
    1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-show more
    Synonyms
    HY-18341A | L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt, hydrate | L-TYROSINE, O-(4-HYDRO...
  9. L-Thyroxine sodium hydrate, Thyroid hormone receptor agonist
    CAS: 25416-65-3 EC Number: 685-634-1 PubChem CID: 23667619 Formula: C15H10I4NNaO4·xH2O Molecular Weight: 798.86 (anhydrous basis)
    Solid ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: S161194
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    Technical Identifiers
    IUPAC Name
    sodium;(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate;hydrate
    SMILES
    C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)[O-])N.O.[Na+]
    InChIKey
    ANMYAHDLKVNJJO-LTCKWSDVSA-M
    InChI
    1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0show more
    Synonyms
    3,3',5,5'-Tetraiodo-L-thyronine monosodium salt | E78443 | Q27107209 | Sodium (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodop...
  10. 3,3′,5-Triiodothyroacetic acid, Agonist of Thyroid hormone receptor-α;Agonist of Thyroid hormone receptor-β
    CAS: 51-24-1 EC Number: 200-086-1 PubChem CID: 5803 Formula: C14H9I3O4 Molecular Weight: 621.93
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥90%
    ● In Stock — US warehouse, ships to EU* Item #: T124580
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    Technical Identifiers
    IUPAC Name
    2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid
    SMILES
    C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(=O)O)I)I)O
    InChIKey
    UOWZUVNAGUAEQC-UHFFFAOYSA-N
    InChI
    1S/C14H9I3O4/c15-9-6-8(1-2-12(9)18)21-14-10(16)3-7(4-11(14)17)5-13(19)20/h1-4,6,18H,5H2,(H,19,20)
    Synonyms
    LIOTHYRONINE SODIUM IMPURITY C [EP IMPURITY] | TIRATRICOL [WHO-DD] | CCG-213970 | NCGC00016227-01 | AMY33311 | BCP071...
  11. 2-Ethylhexyl 4-Methoxycinnamate(OMC)
    CAS: 5466-77-3 EC Number: 226-775-7 Formula: C18H26O3 Molecular Weight: 290.4
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%(GC)
    ● In Stock — Germany Item #: E134205
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    IUPAC Name
    2-ethylhexyl (E)-3-(4-methoxyphenyl)prop-2-enoate
    SMILES
    CCCCC(CC)COC(=O)C=CC1=CC=C(C=C1)OC
    InChIKey
    YBGZDTIWKVFICR-JLHYYAGUSA-N
    InChI
    1S/C18H26O3/c1-4-6-7-15(5-2)14-21-18(19)13-10-16-8-11-17(20-3)12-9-16/h8-13,15H,4-7,14H2,1-3H3/b13-10+
    Synonyms
    OMC | Heliopan New | Surf Bay Lip Balm | Anti AgingStar | Foundation | Tetramethylene Blue | UNII-4Y5P7MUD51 | (E)-Oc...
  12. 3,3',5-Triiodo-L-thyronine, Thyroid hormone receptor agonist
    CAS: 6893-02-3 EC Number: 229-999-3 PubChem CID: 5920 Formula: C15H12I3NO4 Molecular Weight: 650.98
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: T162132
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    Technical Identifiers
    IUPAC Name
    (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
    SMILES
    C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)O)N)I)I)O
    InChIKey
    AUYYCJSJGJYCDS-LBPRGKRZSA-N
    InChI
    1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
    Synonyms
    triiodothyronine | UNII-06LU7C9H1V | REGID_for_CID_5920 | Thyrolar-0.25 | Triiodothyronine, l- | 06LU7C9H1V | DTXSID8...
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Frequently Asked Questions

Which compounds are listed for Thyroid Hormone Receptor?
Compounds associated with Thyroid Hormone Receptor are grouped here under the Vitamin D Related/Nuclear Receptor classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Thyroid Hormone Receptor sit within Vitamin D Related/Nuclear Receptor?
Thyroid Hormone Receptor is one target listing within the Vitamin D Related/Nuclear Receptor classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Thyroid Hormone Receptor?
For compounds listed under Thyroid Hormone Receptor, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Thyroid Hormone Receptor?
Browse the parent Vitamin D Related/Nuclear Receptor listing to reach targets neighbouring Thyroid Hormone Receptor, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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