Toll-like Receptor (TLR)

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  1. N-cyclopentyl-N,N-dimethyl-3,4-bis(tetradecyloxy)-benzenemethanaminium, iodide
    CAS: 1202208-36-3 PubChem CID: 25223004 Formula: C42H78INO2 Molecular Weight: 756
    ◐ .Made to order · 8–12 wks Item #: N343863
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    IUPAC Name
    cyclopentyl-[[3,4-di(tetradecoxy)phenyl]methyl]-dimethylazanium;iodide
    SMILES
    CCCCCCCCCCCCCCOC1=C(C=C(C=C1)C[N+](C)(C)C2CCCC2)OCCCCCCCCCCCCCC.[I-]
    InChIKey
    UXOPVNPWTUWUEA-UHFFFAOYSA-M
    InChI
    1S/C42H78NO2.HI/c1-5-7-9-11-13-15-17-19-21-23-25-29-35-44-41-34-33-39(38-43(3,4)40-31-27-28-32-40)37-42(41)45-36-30-26-24-22-20-18-16-14-12-10-8-6-2;/show more
    Synonyms
    MS-31339 | CAY10614 | N-{[3,4-BIS(TETRADECYLOXY)PHENYL]METHYL}-N,N-DIMETHYLCYCLOPENTANAMINIUM IODIDE | AKOS040756392 ...
  2. Chloranil (TCBQ)
    CAS: 118-75-2 EC Number: 204-274-4 PubChem CID: 8371 Formula: C6Cl4O2 Molecular Weight: 245.88
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: T105286
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    IUPAC Name
    2,3,5,6-tetrachlorocyclohexa-2,5-diene-1,4-dione
    SMILES
    C1(=C(C(=O)C(=C(C1=O)Cl)Cl)Cl)Cl
    InChIKey
    UGNWTBMOAKPKBL-UHFFFAOYSA-N
    InChI
    1S/C6Cl4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11
    Synonyms
    2,3,5,6-Tetrachloro-p-benzoquinone | DivK1c_006946 | EN300-18125 | Spectrum5_001386 | Spergon | 2,5,6-Tetrachloroquin...
  3. Isofraxidin
    CAS: 486-21-5 Formula: C11H10O5 Molecular Weight: 222.19
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: I101319
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    IUPAC Name
    7-hydroxy-6,8-dimethoxychromen-2-one
    SMILES
    COC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O
    InChIKey
    HOEVRHHMDJKUMZ-UHFFFAOYSA-N
    InChI
    1S/C11H10O5/c1-14-7-5-6-3-4-8(12)16-10(6)11(15-2)9(7)13/h3-5,13H,1-2H3
    Synonyms
    CCG-266730 | FT-0607262 | Phytodolor | HOEVRHHMDJKUMZ-UHFFFAOYSA-N | HY-N0774 | NSC324637 | NSC-324637 | 2H-1-Benzopy...
  4. (±)-Naringenin
    CAS: 67604-48-2 EC Number: 266-769-1 Formula: C15H12O5 Molecular Weight: 272.26
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ● In Stock — US warehouse, ships to EU* Item #: R135669
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    IUPAC Name
    5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
    SMILES
    C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O
    InChIKey
    FTVWIRXFELQLPI-UHFFFAOYSA-N
    InChI
    1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
    Synonyms
    4H-1-Benzopyran-4-one,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)- | EINECS 266-769-1 | NCGC00017346-04 | NCGC0...
  5. Gardiquimod
    CAS: 1020412-43-4 EC Number: 806-274-5 Formula: C17H23N5O Molecular Weight: 313.4
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: G274801
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    IUPAC Name
    1-[4-amino-2-(ethylaminomethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
    SMILES
    CCNCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
    InChIKey
    FHJATBIERQTCTN-UHFFFAOYSA-N
    InChI
    1S/C17H23N5O/c1-4-19-9-13-21-14-15(22(13)10-17(2,3)23)11-7-5-6-8-12(11)20-16(14)18/h5-8,19,23H,4,9-10H2,1-3H3,(H2,18,20)
    Synonyms
    1-[4-amino-2-(ethylaminomethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol | 1-(4-amino-2-((ethylamino)methyl)-1...
  6. 5-Chloroisoquinoline
    CAS: 5430-45-5 Formula: C9H6ClN Molecular Weight: 163.6
    ● In Stock — US warehouse, ships to EU* Item #: C135973
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    IUPAC Name
    5-chloroisoquinoline
    SMILES
    C1=CC2=C(C=CN=C2)C(=C1)Cl
    InChIKey
    PJHSMEMFNSINJE-UHFFFAOYSA-N
    InChI
    1S/C9H6ClN/c10-9-3-1-2-7-6-11-5-4-8(7)9/h1-6H
    Synonyms
    5-Chloro-isoquinoline
  7. SM 324405
    CAS: 677773-91-0 PubChem CID: 23079483 Formula: C19H23N5O4 Molecular Weight: 385.42
    ● In Stock — US warehouse, ships to EU* Item #: S288301
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    IUPAC Name
    methyl 2-[3-[(6-amino-2-butoxy-8-oxo-7H-purin-9-yl)methyl]phenyl]acetate
    SMILES
    CCCCOC1=NC(=C2C(=N1)N(C(=O)N2)CC3=CC=CC(=C3)CC(=O)OC)N
    InChIKey
    MXILFZWMVNDOIZ-UHFFFAOYSA-N
    InChI
    1S/C19H23N5O4/c1-3-4-8-28-18-22-16(20)15-17(23-18)24(19(26)21-15)11-13-7-5-6-12(9-13)10-14(25)27-2/h5-7,9H,3-4,8,10-11H2,1-2H3,(H,21,26)(H2,20,22,23)
    Synonyms
    Methyl 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]benzeneacetate
  8. 5-Hydroxy-1,4-naphthoquinone
    CAS: 481-39-0 EC Number: 207-567-5 Formula: C10H6O3 Molecular Weight: 174.16
    ● In Stock — US warehouse, ships to EU* Item #: H136625
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    IUPAC Name
    5-hydroxynaphthalene-1,4-dione
    SMILES
    C1=CC2=C(C(=O)C=CC2=O)C(=C1)O
    InChIKey
    KQPYUDDGWXQXHS-UHFFFAOYSA-N
    InChI
    1S/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12H
    Synonyms
    5-Hydroxy-1,4-naphthoquinone, 97% | 1, 8-hydroxy- | HMS503M13 | NSC 153189 | SDCCGMLS-0066542.P001 | KBio1_001026 | 1...
  9. 5-Iodoisoquinoline
    CAS: 58142-99-7 Formula: C9H6IN Molecular Weight: 255.06
    ● In Stock — US warehouse, ships to EU* Item #: I194049
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    Technical Identifiers
    IUPAC Name
    5-iodoisoquinoline
    SMILES
    C1=CC2=C(C=CN=C2)C(=C1)I
    InChIKey
    CUILFTFMBBGSFT-UHFFFAOYSA-N
    InChI
    1S/C9H6IN/c10-9-3-1-2-7-6-11-5-4-8(7)9/h1-6H
    Synonyms
    Isoquinoline, 5-iodo- (9CI) | DTXSID90464455 | SY113381 | DSRM-3716 | 5-iodoisoquinoline | MFCD11226893 | ZB1085 | O1...
  10. Atractylenolide I
    CAS: 73069-13-3 Formula: C15H18O2 Molecular Weight: 230.3
    Solid Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● In Stock — US warehouse, ships to EU* Item #: A304497
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    IUPAC Name
    (4aS,8aS)-3,8a-dimethyl-5-methylidene-4a,6,7,8-tetrahydro-4H-benzo[f][1]benzofuran-2-one
    SMILES
    CC1=C2CC3C(=C)CCCC3(C=C2OC1=O)C
    InChIKey
    ZTVSGQPHMUYCRS-SWLSCSKDSA-N
    InChI
    1S/C15H18O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h8,12H,1,4-7H2,2-3H3/t12-,15+/m0/s1
    Synonyms
    HMS3886N08 | Atractylenolide I | Atractylenolide I, >=98% (HPLC) | s8291 | (4aS,8aS)-3,8a-dimethyl-5-methylene-4a,5,6...
  11. Bropirimine
    CAS: 56741-95-8 Formula: C10H8BrN3O Molecular Weight: 266.09
    ● In Stock — US warehouse, ships to EU* Item #: B134495
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    IUPAC Name
    2-amino-5-bromo-4-phenyl-1H-pyrimidin-6-one
    SMILES
    C1=CC=C(C=C1)C2=C(C(=O)NC(=N2)N)Br
    InChIKey
    CIUUIPMOFZIWIZ-UHFFFAOYSA-N
    InChI
    1S/C10H8BrN3O/c11-7-8(6-4-2-1-3-5-6)13-10(12)14-9(7)15/h1-5H,(H3,12,13,14,15)
    Synonyms
    4(3H)-Pyrimidinone, 2-amino-5-bromo-6-phenyl- | Bropirimine | BROPIRIMINE [JAN] | SCHEMBL4058 | AB00081669-01 | CHEBI...
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Frequently Asked Questions

What can I find under Toll-like Receptor (TLR)?
This listing collects compounds associated with Toll-like Receptor (TLR) within our Immunology/Inflammation area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Toll-like Receptor (TLR)?
Consider the reported potency of each Toll-like Receptor (TLR) compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Toll-like Receptor (TLR) compounds?
Each Toll-like Receptor (TLR) product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Toll-like Receptor (TLR) compounds by activity or structure?
Yes. Filter the Toll-like Receptor (TLR) listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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