Transthyretin (TTR)

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  1. A 1120, Inhibitor of retinol binding protein 4
    CAS: 1152782-19-8 Formula: C20H19F3N2O3 Molecular Weight: 392.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: A288923
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    IUPAC Name
    2-[[4-[2-(trifluoromethyl)phenyl]piperidine-1-carbonyl]amino]benzoic acid
    SMILES
    C1CN(CCC1C2=CC=CC=C2C(F)(F)F)C(=O)NC3=CC=CC=C3C(=O)O
    InChIKey
    MEAQCLPMSVEOQF-UHFFFAOYSA-N
    InChI
    1S/C20H19F3N2O3/c21-20(22,23)16-7-3-1-5-14(16)13-9-11-25(12-10-13)19(28)24-17-8-4-2-6-15(17)18(26)27/h1-8,13H,9-12H2,(H,24,28)(H,26,27)
    Synonyms
    GTPL8792 | HY-107633 | A 1120 | 2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid | NCGC00...
  2. gamma-Mangostin
    CAS: 31271-07-5 Formula: C23H24O6 Molecular Weight: 396.43
    ● In Stock — US warehouse, ships to EU* Item #: G169488
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    IUPAC Name
    1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one
    SMILES
    CC(=CCC1=C(C2=C(C=C1O)OC3=C(C2=O)C(=C(C(=C3)O)O)CC=C(C)C)O)C
    InChIKey
    VEZXFTKZUMARDU-UHFFFAOYSA-N
    InChI
    1S/C23H24O6/c1-11(2)5-7-13-15(24)9-18-20(22(13)27)23(28)19-14(8-6-12(3)4)21(26)16(25)10-17(19)29-18/h5-6,9-10,24-27H,7-8H2,1-4H3
    Synonyms
    9H-Xanthen-9-one, 1,3,6,7-tetrahydroxy-2,8-bis(3-methyl-2-butenyl)- | PDSP2_000060 | SCHEMBL3753526 | BDBM50241453 | ...
  3. Tafamidis, Transthyretin stabiliser
    CAS: 594839-88-0 EC Number: 813-715-5 PubChem CID: 11001318 Formula: C14H7Cl2NO3 Molecular Weight: 308.12
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: T424958
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    IUPAC Name
    2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
    SMILES
    C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
    InChIKey
    TXEIIPDJKFWEEC-UHFFFAOYSA-N
    InChI
    1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)
    Synonyms
    TAFAMIDIS|594839-88-0|Vyndamax|FX-1006|2-(3,5-Dichlorophenyl)-1,3-Benzoxazole-6-Carboxylic Acid|tafamidisum|2-(3,5-Di...
  4. Tafamidis, Transthyretin stabiliser
    CAS: 594839-88-0 EC Number: 813-715-5 PubChem CID: 11001318 Formula: C14H7Cl2NO3 Molecular Weight: 308.12
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● In Stock — US warehouse, ships to EU* Item #: T413467
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    Technical Identifiers
    IUPAC Name
    2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid
    SMILES
    C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
    InChIKey
    TXEIIPDJKFWEEC-UHFFFAOYSA-N
    InChI
    1S/C14H7Cl2NO3/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13/h1-6H,(H,18,19)
    Synonyms
    AKOS017550076 | Tafamidis [USAN] | DTXCID20130676 | FX-1005 | TAFAMIDIS [MI] | BDBM50197883 | s6465 | 6-Benzoxazoleca...
  5. WAY-300033
    CAS: 23983-05-3 PubChem CID: 689165 Formula: C16H9ClN2OS Molecular Weight: 312.77
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: W422800
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    IUPAC Name
    (2Z)-2-[(2-chlorophenyl)methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-1-one
    SMILES
    C1=CC=C(C(=C1)C=C2C(=O)N3C4=CC=CC=C4N=C3S2)Cl
    InChIKey
    LSMPFFSYANAQSU-ZROIWOOFSA-N
    InChI
    1S/C16H9ClN2OS/c17-11-6-2-1-5-10(11)9-14-15(20)19-13-8-4-3-7-12(13)18-16(19)21-14/h1-9H/b14-9-
    Synonyms
    2-(2-Chlorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one | HY-153577 | Thiazolo(3,2-a)benzimidazol-3(2H)-one,...
  6. WAY-300033
    CAS: 23983-05-3 PubChem CID: 689165 Formula: C16H9ClN2OS Molecular Weight: 312.77
    ● In Stock — US warehouse, ships to EU* Item #: W416818
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    Technical Identifiers
    IUPAC Name
    (2Z)-2-[(2-chlorophenyl)methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-1-one
    SMILES
    C1=CC=C(C(=C1)C=C2C(=O)N3C4=CC=CC=C4N=C3S2)Cl
    InChIKey
    LSMPFFSYANAQSU-ZROIWOOFSA-N
    InChI
    1S/C16H9ClN2OS/c17-11-6-2-1-5-10(11)9-14-15(20)19-13-8-4-3-7-12(13)18-16(19)21-14/h1-9H/b14-9-
    Synonyms
    2-(2-Chlorobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one | HY-153577 | Thiazolo(3,2-a)benzimidazol-3(2H)-one,...
  7. Inotersen sodium
    CAS: 1432726-13-0 PubChem CID: 121493436 Molecular Weight: 7601.00
    ◐ .Made to order · 8–12 wks Item #: I647785
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    Technical Identifiers
    SMILES
    CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=S)([O-])O[C@H]3C[C@@H](O[C@@H]3COP(=S)([O-])O[C@H]4C[C@@H](O[C@@H]4COP(=S)([O-])O[C@@H]5[C@H](O[C@H]([C@show more
  8. Acoramidis hydrochloride
    CAS: 2242751-53-5 PubChem CID: 135307127 Formula: C15H18ClFN2O3 Molecular Weight: 328.77
    ◐ .Made to order · 8–12 wks Item #: A646727
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    IUPAC Name
    3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid;hydrochloride
    SMILES
    CC1=C(C(=NN1)C)CCCOC2=C(C=CC(=C2)C(=O)O)F.Cl
    InChIKey
    MGFZEARHINUOMX-UHFFFAOYSA-N
    InChI
    1S/C15H17FN2O3.ClH/c1-9-12(10(2)18-17-9)4-3-7-21-14-8-11(15(19)20)5-6-13(14)16;/h5-6,8H,3-4,7H2,1-2H3,(H,17,18)(H,19,20);1H
    Synonyms
    Acoramidis hydrochloride [USAN] | UNII-VY9C88C2NV | Acoramidis (hydrochloride) | Alxn2060 hydrochloride | Alxn-2060 h...
  9. Dichlorophenyl-ABA
    CAS: 18201-65-5 PubChem CID: 644279 Formula: C13H9Cl2NO2 Molecular Weight: 282.12
    ◐ .Made to order · 8–12 wks Item #: D648506
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    Technical Identifiers
    IUPAC Name
    2-(3,5-dichloroanilino)benzoic acid
    SMILES
    C1=CC=C(C(=C1)C(=O)O)NC2=CC(=CC(=C2)Cl)Cl
    InChIKey
    FNGSQOJHNAYHAT-UHFFFAOYSA-N
    InChI
    1S/C13H9Cl2NO2/c14-8-5-9(15)7-10(6-8)16-12-4-2-1-3-11(12)13(17)18/h1-7,16H,(H,17,18)
    Synonyms
    benzoic acid, 2-[(3,5-dichlorophenyl)amino]- | benzoic acid,2-[(3,5-dichlorophenyl)amino]- | 2-[(3,5-dichlorophenyl)a...
  10. Tafamidis meglumine, Transthyretin stabiliser
    CAS: 951395-08-7 EC Number: 813-716-0 Formula: C21H24Cl2N2O8 Molecular Weight: 503.33
    ● In Stock — US warehouse, ships to EU* Item #: T651781
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    Technical Identifiers
    IUPAC Name
    2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
    SMILES
    CNCC(C(C(C(CO)O)O)O)O.C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl
    InChIKey
    DQJDBUPLRMRBAB-WZTVWXICSA-N
    InChI
    1S/C14H7Cl2NO3.C7H17NO5/c15-9-3-8(4-10(16)6-9)13-17-11-2-1-7(14(18)19)5-12(11)20-13;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-6H,(H,18,19);4-13H,2-3H2,1H3/t;4-show more
    Synonyms
    Tafamidis meglumine | Vyndaqel | (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol 2-(3,5-dichlorophenyl)benzo[d]...
  11. 3-[3-(3,5-Dimethyl-1h-Pyrazol-4-Yl)propoxy]-4-Fluorobenzoic Acid, Transthyretin stabiliser
    CAS: 1446711-81-4 PubChem CID: 71464713 Formula: C15H17FN2O3 Molecular Weight: 292.3
    ◐ .Made to order · 8–12 wks Item #: D671270
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    Technical Identifiers
    IUPAC Name
    3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid
    SMILES
    CC1=C(C(=NN1)C)CCCOC2=C(C=CC(=C2)C(=O)O)F
    InChIKey
    WBFUHHBPNXWNCC-UHFFFAOYSA-N
    InChI
    1S/C15H17FN2O3/c1-9-12(10(2)18-17-9)4-3-7-21-14-8-11(15(19)20)5-6-13(14)16/h5-6,8H,3-4,7H2,1-2H3,(H,17,18)(H,19,20)
    Synonyms
    Acoramidis | 4hiq | 3-[3-(3,5-Dimethyl-1h-Pyrazol-4-Yl)propoxy]-4-Fluorobenzoic Acid | HY-109165 | AG10 | SCHEMBL1581...
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Frequently Asked Questions

What can I find under Transthyretin (TTR)?
This listing collects compounds associated with Transthyretin (TTR) within our Neuronal Signaling area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Transthyretin (TTR)?
Consider the reported potency of each Transthyretin (TTR) compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Transthyretin (TTR) compounds?
Each Transthyretin (TTR) product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Transthyretin (TTR) compounds by activity or structure?
Yes. Filter the Transthyretin (TTR) listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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