TSH Receptor

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  1. D3-βArr
    CAS: 662164-09-2 Formula: C20H23N5 Molecular Weight: 333.43
    ● In Stock — US warehouse, ships to EU* Item #: D412320
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    Technical Identifiers
    IUPAC Name
    N-(1-phenylethyl)-2-piperazin-1-ylquinazolin-4-amine
    SMILES
    CC(C1=CC=CC=C1)NC2=NC(=NC3=CC=CC=C32)N4CCNCC4
    InChIKey
    LOGWGZNWEWFTJV-UHFFFAOYSA-N
    InChI
    1S/C20H23N5/c1-15(16-7-3-2-4-8-16)22-19-17-9-5-6-10-18(17)23-20(24-19)25-13-11-21-12-14-25/h2-10,15,21H,11-14H2,1H3,(H,22,23,24)
    Synonyms
    NCGC00379308 | N-(1-Phenylethyl)-2-(1-piperazinyl)-4-quinazolinamine, N-(1-Phenylethyl)-2-(piperazin-1-yl)quinazolin-...
  2. Teprotumumab (anti-IGF1R), ANTAGONIST of Insulin-like growth factor I receptor antagonist
    CAS: 1036734-93-6
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab170834
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    Technical Identifiers
    Associated targets
    IGF1R
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    CD221 antibody | CD221 antigen antibody | IGF 1 receptor antibody | IGF 1R antibody | IGF I receptor antibody | IGF-I...
  3. VA-K-14 hydrochloride
    CAS: 1171341-19-7 PubChem CID: 17479126 Formula: C18H16ClN3S Molecular Weight: 341.86
    ◐ .Made to order · 8–12 wks Item #: V648128
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    IUPAC Name
    N-methyl-4-(2-phenyl-1H-indol-3-yl)-1,3-thiazol-2-amine;hydrochloride
    SMILES
    CNC1=NC(=CS1)C2=C(NC3=CC=CC=C32)C4=CC=CC=C4.Cl
    InChIKey
    MMEANJJDNROSBC-UHFFFAOYSA-N
    InChI
    1S/C18H15N3S.ClH/c1-19-18-21-15(11-22-18)16-13-9-5-6-10-14(13)20-17(16)12-7-3-2-4-8-12;/h2-11,20H,1H3,(H,19,21);1H
  4. TSHR antagonist S37b
    CAS: 2143452-22-4 Formula: C25H20N2O3S2 Molecular Weight: 460.57
    ◐ .Made to order · 8–12 wks Item #: T648280
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    Technical Identifiers
    SMILES
    O=C(N1)SC([C@@H]2C3=CC=CC=C3)=C1S[C@]([C@]2([H])[C@]4([H])[C@]56[H])([H])[C@@](C4)([H])[C@@]6([H])C(N(C7=CC=CC=C7)C5=O)=O
  5. Org41841
    CAS: 301847-37-0 PubChem CID: 9887381 Formula: C19H22N4O2S2 Molecular Weight: 402.53
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: O648726
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    Technical Identifiers
    IUPAC Name
    5-amino-N-tert-butyl-4-(3-methoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
    SMILES
    CC(C)(C)NC(=O)C1=C(C2=C(N=C(N=C2S1)SC)C3=CC(=CC=C3)OC)N
    InChIKey
    DVSFSADBOJYPGF-UHFFFAOYSA-N
    InChI
    1S/C19H22N4O2S2/c1-19(2,3)23-16(24)15-13(20)12-14(10-7-6-8-11(9-10)25-4)21-18(26-5)22-17(12)27-15/h6-9H,20H2,1-5H3,(H,23,24)
    Synonyms
    cid_9887381 | 5-amino-N-tert-butyl-4-(3-methoxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide | CHEBI:...
  6. ML-109
    CAS: 1186649-91-1 PubChem CID: 25246343 Formula: C31H29N3O5 Molecular Weight: 523.58
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: M651343
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    Technical Identifiers
    IUPAC Name
    N-[4-[[5-(3-benzyl-5-hydroxy-4-oxo-1,2-dihydroquinazolin-2-yl)-2-methoxyphenyl]methoxy]phenyl]acetamide
    SMILES
    CC(=O)NC1=CC=C(C=C1)OCC2=C(C=CC(=C2)C3NC4=C(C(=CC=C4)O)C(=O)N3CC5=CC=CC=C5)OC
    InChIKey
    JRVXFGNCHKHBPA-UHFFFAOYSA-N
    InChI
    1S/C31H29N3O5/c1-20(35)32-24-12-14-25(15-13-24)39-19-23-17-22(11-16-28(23)38-2)30-33-26-9-6-10-27(36)29(26)31(37)34(30)18-21-7-4-3-5-8-21/h3-17,30,33,show more
    Synonyms
    AC-36479 | AKOS037648530 | ML 109; ML109 | NCGC00161870-01 | CHEBI:91942 | D81075 | MFCD31746908 | Q27163740 | BS-144...
  7. ML224
    CAS: 1338824-21-7 PubChem CID: 50897809 Formula: C31H31N3O5 Molecular Weight: 525.59
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ◐ .Made to order · 8–12 wks Item #: M651548
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    Technical Identifiers
    IUPAC Name
    N-[4-[[5-[3-(furan-2-ylmethyl)-4-oxo-1,2-dihydroquinazolin-2-yl]-2-methoxyphenyl]methoxy]-3,5-dimethylphenyl]acetamide
    SMILES
    CC1=CC(=CC(=C1OCC2=C(C=CC(=C2)C3NC4=CC=CC=C4C(=O)N3CC5=CC=CO5)OC)C)NC(=O)C
    InChIKey
    BFTSWGYWHRJVNI-UHFFFAOYSA-N
    InChI
    1S/C31H31N3O5/c1-19-14-24(32-21(3)35)15-20(2)29(19)39-18-23-16-22(11-12-28(23)37-4)30-33-27-10-6-5-9-26(27)31(36)34(30)17-25-8-7-13-38-25/h5-16,30,33Hshow more
    Synonyms
    NCGC00242364 | ANTAG3
  8. TSHR antagonist S37a
    CAS: 2143452-20-2 Formula: C25H20N2O3S2 Molecular Weight: 460.57
    ◐ .Made to order · 8–12 wks Item #: T648377
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    Pricing & Pack Sizes
    Technical Identifiers
    SMILES
    O=C(N1)SC([C@H]2C3=CC=CC=C3)=C1S[C@@]([C@@]2([H])[C@@]4([H])[C@@]56[H])([H])[C@](C4)([H])[C@]6([H])C(N(C7=CC=CC=C7)C5=O)=O
  9. Benzyl 6-methyl-2-oxo-4-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
    CAS: 512840-45-8 EC Number: 975-935-9 Formula: C20H17F3N2O3 Molecular Weight: 390.4
    ◐ .Made to order · 8–12 wks Item #: B1265476
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    Technical Identifiers
    IUPAC Name
    benzyl 6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate
    SMILES
    CC1=C(C(NC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)OCC3=CC=CC=C3
    InChIKey
    CRJLZKUONIFOEQ-UHFFFAOYSA-N
    InChI
    1S/C20H17F3N2O3/c1-12-16(18(26)28-11-13-5-3-2-4-6-13)17(25-19(27)24-12)14-7-9-15(10-8-14)20(21,22)23/h2-10,17H,11H2,1H3,(H2,24,25,27)
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R&D Use Only Products supplied for research and development use

Frequently Asked Questions

How is the TSH Receptor listing put together?
It draws on reported TSH Receptor annotations within GPCR/G Protein and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a TSH Receptor modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the TSH Receptor entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for TSH Receptor compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For TSH Receptor work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the TSH Receptor compound I need is not listed?
Search by CAS number or SMILES first, since analogs of TSH Receptor compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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