Brain and Neurological Disease Targets

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  1. Supercinnamaldehyde
    CAS: 70351-51-8 EC Number: 635-329-4 PubChem CID: 12480412 Formula: C12H11NO2 Molecular Weight: 201.22
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: S275603
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    IUPAC Name
    (3Z)-1-methyl-3-(2-oxopropylidene)indol-2-one
    SMILES
    CC(=O)C=C1C2=CC=CC=C2N(C1=O)C
    InChIKey
    CZKBLHCEDVWPRN-YFHOEESVSA-N
    InChI
    1S/C12H11NO2/c1-8(14)7-10-9-5-3-4-6-11(9)13(2)12(10)15/h3-7H,1-2H3/b10-7-
    Synonyms
    (3Z)-1-methyl-3-(2-oxopropylidene)-2,3-dihydro-1H-indol-2-one | LP00237 | NCGC00185999-01 | HMS3260P15 | supercinnama...
  2. Recombinant Human GM-CSF Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥98%(SDS-PAGE&HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: rp146523
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    Technical Identifiers
    Species
    Human
    Accession #
    P04141
    Expression system
    E. coli
    Protein Day
    No tag
    Endotoxin Concentration
    <0.01 EU/μg
    Bioactivity
    Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is typically < 0.2ng/mL.
    Synonyms
    Human Granulocyte-Macrophage Colony Stimulating Factor | Colony stimulating factor 2 (granulocyte-macrophage) | Colon...
  3. Native Human Myeloperoxidase Protein
    Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥80%(SDS-PAGE) See COA
    ● In Stock — US warehouse, ships to EU* Item #: M572740
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    Species
    Human
    Accession #
    P05164
    Synonyms
    MPO Human | Myeloperoxidase (MPO | non recombinant) | MPO | mpx | myeloid-specific peroxidase | Myeloperoxidase | Mye...
  4. Recombinant Rat GM-CSF Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥98%(SDS-PAGE&HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: rp155067
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    Species
    Rat
    Accession #
    P48750
    Expression system
    E. coli
    Protein Day
    No tag
    Endotoxin Concentration
    <0.01 EU/μg
    Bioactivity
    Measured in a cell proliferation assay using murine FDC-P1 cells. The ED50 for this effect is typically <0.02 ng/mL.
    Synonyms
    Colony stimulating factor 2 (granulocyte-macrophage) | Colony-stimulating factor | CSF | CSF2 | CSF-2 | GMCSF | GM-CS...
  5. Recombinant Human VEGF Protein
    CAS: 127464-60-2 Formula: Molecular Weight: 19.2 kD(单体)
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥95%(SDS-PAGE)
    ● In Stock — US warehouse, ships to EU* Item #: rp155965
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    Technical Identifiers
    Species
    Human
    Accession #
    P15692-4
    Expression system
    Oryza sativa
    Protein Day
    No tag
    Endotoxin Concentration
    <0.2 EU/μg
    Bioactivity
    The ED50 value was lower than 10.0 ng/ml, that is, the corresponding active unit was greater than or equal to 1 x 10^5 units/mg by primary HUVECs cell proliferation method.
    Synonyms
    MVCD1 | VAS | Vascular endothelial growth factor A | Vascular permeability factor | Vasculotropin | VEGF | VEGFA | VE...
  6. Recombinant Human TNFRSF1A Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥97%(SDS-PAGE&HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: rp152513
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    Technical Identifiers
    Species
    Human
    Accession #
    P19438
    Expression system
    E. coli
    Protein Day
    No tag
    Endotoxin Concentration
    <0.1 EU/μg
    Bioactivity
    Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha.
    Synonyms
    CD120a antigen | CD120a | FPF | p55 | p55-R | p60 | TNF RI | TNFARMGC19588 | TNF-R | TNF-R1 | TNFR1TBP1 | TNFR55 | TN...
  7. SB-649868, Orexin receptor 2 antagonist
    CAS: 380899-24-1 Formula: C26H24FN3O3S Molecular Weight: 477.55
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: S613466
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    IUPAC Name
    N-[[(2S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
    SMILES
    CC1=NC(=C(S1)C2=CC=C(C=C2)F)C(=O)N3CCCCC3CNC(=O)C4=C5C=COC5=CC=C4
    InChIKey
    ZJXIUGNEAIHSBI-IBGZPJMESA-N
    InChI
    1S/C26H24FN3O3S/c1-16-29-23(24(34-16)17-8-10-18(27)11-9-17)26(32)30-13-3-2-5-19(30)15-28-25(31)21-6-4-7-22-20(21)12-14-33-22/h4,6-12,14,19H,2-3,5,13,1show more
    Synonyms
    GTPL4461 | C26H24FN3O3S | SB649868 | SB-649868 | SCHEMBL8045969 | Q7388914 | N-[[(2S)-1-[[5-(4-Fluorophenyl)-2-methyl...
  8. Recombinant Human IL-2 Receptor Alpha Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥97%(SDS-PAGE)
    ● In Stock — US warehouse, ships to EU* Item #: rp147480
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    Technical Identifiers
    Species
    Human
    Accession #
    P01589
    Expression system
    HEK293
    Protein Day
    C-His
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    1. Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.2 ‑1.2 µg/mL in the presence of 30 ng/mL of recombinant human IL-2. 2. Immobilized Recombinant Human IL-2 Protein (rp156004) at 1 μg/mL can bind biotinylated Recombinant Human IL-2 Receptor Alpha Protein (rp147480).
    Synonyms
    Interleukin 2 receptor alpha chain | CD25 | CD25 antigen | IDDM10 | IL 2 receptor alpha subunit | IL-2 receptor subun...
  9. Recombinant Human Alpha-synuclein Protein
    Lyophilized Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥90%(SDS-PAGE)
    ● In Stock — US warehouse, ships to EU* Item #: rp156673
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    Technical Identifiers
    Species
    Human
    Accession #
    P37840
    Expression system
    E. coli
    Protein Day
    N-His
    Endotoxin Concentration
    <1.0 EU/μg
    Synonyms
    NACP | Non-A beta component of AD amyloid | Non-A4 component of amyloid precursor
  10. Recombinant Human IL-6R Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥90%(SDS-PAGE)
    ● In Stock — US warehouse, ships to EU* Item #: rp147628
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    Technical Identifiers
    Species
    Human
    Accession #
    P08887
    Expression system
    HEK293
    Protein Day
    C-His
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    1. Immobilized Recombinant Human IL-6 Protein at 2 μg/mL can bind Recombinant Human IL-6R Protein (rp147628) the EC50 is 8.0 - 24.0 ng/mL. 2. Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10.0 - 60.0 ng/mL.3. Using the Octet RED System, the affinity constant (Kd) of Recombinant Human IL-6R Protein (rp147628) bound Anti-IL6R Antibody was 0.1 nM.
    Synonyms
    CD126 | gp80 | IL-6 R alpha | IL6Q | IL6R alpha | IL-6R alpha | IL6R | IL-6R-1 | IL6RA | IL-6Ra | IL6RQ | interleukin...
  11. Recombinant Human Nectin-2/CD112 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)
    ● In Stock — US warehouse, ships to EU* Item #: rp149154
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    Technical Identifiers
    Species
    Human
    Accession #
    Q92692
    Expression system
    HEK293
    Protein Day
    No tag
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    Recombinant Human Nectin-2/CD112 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human DNAM-1/CD226 hFc has been identified as an interactor of Nectin-2, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-2 and recombinant DNAM-1/CD226 hFc.
    Synonyms
    CD112 antigen | CD112 | Herpes virus entry mediator B | Herpesvirus entry mediator B | herpesvirus entry protein B | ...
  12. Recombinant Human Clusterin Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥90%(SDS-PAGE)
    ● In Stock — US warehouse, ships to EU* Item #: rp144473
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    P10909-1
    Expression system
    HEK293
    Protein Day
    C-His
    Endotoxin Concentration
    <0.1 EU/μg
    Bioactivity
    Measured by its ability to induce clustering of Caki‑2 human clear cell carcinoma epithelial cells.
    Synonyms
    40 | AAG4 | Aging-associated gene 4 protein | aging-associated protein 4 | Apo-J | APOJ | ApoJalpha | ApoJbeta | Apol...
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Define the transformation first, then narrow the Brain and Neurological Disease Targets listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
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Review the lot-specific Certificate of Analysis for the Brain and Neurological Disease Targets product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
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Yes. Within Brain and Neurological Disease Targets you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

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