Bcr-Abl
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175 products
Popular Products
- GNF-2Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: G126166View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[6-[4-(trifluoromethoxy)anilino]pyrimidin-4-yl]benzamide
- SMILES
- C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F
- InChIKey
- WEVYNIUIFUYDGI-UHFFFAOYSA-N
- InChI
- 1S/C18H13F3N4O2/c19-18(20,21)27-14-6-4-13(5-7-14)25-16-9-15(23-10-24-16)11-2-1-3-12(8-11)17(22)26/h1-10H,(H2,22,26)(H,23,24,25)
- Synonyms
- HMS3265C23 | Bcr-abl inhibitor GNF-2 | HMS3333I20 | SB19395 | SW219739-1 | 3-[6-(4-trifluoromethoxyphenyl-amino)-pyri...
- Nocodazole● In Stock — US warehouse, ships to EU* Item #: N129755View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
- SMILES
- COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
- InChIKey
- KYRVNWMVYQXFEU-UHFFFAOYSA-N
- InChI
- 1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)
- Synonyms
- HMS587E01 | Methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate | MLS001164242 | DTXCID7011800 | KBio3_0027...
- Nilotinib (AMN-107), Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: N126111View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
- SMILES
- CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
- InChIKey
- HHZIURLSWUIHRB-UHFFFAOYSA-N
- InChI
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- Synonyms
- Nilotinib [USAN:INN:BAN] | 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trif...
- Imatinib (STI571), Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: I124963View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
- SMILES
- CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
- InChIKey
- KTUFNOKKBVMGRW-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide | CGP-57148 | ...
- Imatinib-d8CAS: 1092942-82-9 Formula: C29H23D8N7O Molecular Weight: 501.65● In Stock — US warehouse, ships to EU* Item #: I341912View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)methyl]benzamide
- SMILES
- CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
- InChIKey
- KTUFNOKKBVMGRW-AZGHYOHESA-N
- InChI
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- Synonyms
- 4-{[4-Methyl(~2~H_8_)piperazin-1-yl]methyl}-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide | D...
- Tyrphostin AG 957Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: T275041View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- methyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate
- SMILES
- COC(=O)C1=CC=C(C=C1)NCC2=C(C=CC(=C2)O)O
- InChIKey
- QSFREBZMBNRGOK-UHFFFAOYSA-N
- InChI
- 1S/C15H15NO4/c1-20-15(19)10-2-4-12(5-3-10)16-9-11-8-13(17)6-7-14(11)18/h2-8,16-18H,9H2,1H3
- Synonyms
- NCI60_018914 | 4-[(2,5-dihydroxyphenyl)methylamino]benzoic acid methyl ester | Benzoic acid,4-[[(2,5-dihydroxyphenyl)...
- KW-2449, Tyrosine-protein kinase ABL inhibitorCAS: 1000669-72-6 Formula: C20H20N4O Molecular Weight: 332.4Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: K127169View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone
- SMILES
- C1CN(CCN1)C(=O)C2=CC=C(C=C2)C=CC3=NNC4=CC=CC=C43
- InChIKey
- YYLKKYCXAOBSRM-JXMROGBWSA-N
- InChI
- 1S/C20H20N4O/c25-20(24-13-11-21-12-14-24)16-8-5-15(6-9-16)7-10-19-17-3-1-2-4-18(17)22-23-19/h1-10,21H,11-14H2,(H,22,23)/b10-7+
- Synonyms
- (E)-1-{4-[2-(1H-indazol-3-yl)vinyl]benzoyl}piperazine | NCGC00346569-07 | (E)-(4-(2-(1H-Indazol-3-yl)vinyl)-phenyl)(p...
- N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide● In Stock — US warehouse, ships to EU* Item #: N183541View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide
- SMILES
- CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)Cl
- InChIKey
- LMXUWARKUIELGT-UHFFFAOYSA-N
- InChI
- 1S/C16H13Cl2N5OS/c1-8-4-3-5-10(17)14(8)23-15(24)11-7-19-16(25-11)22-13-6-12(18)20-9(2)21-13/h3-7H,1-2H3,(H,23,24)(H,19,20,21,22)
- Synonyms
- 2-[(6-Chloro-2-methyl-4-pyrimidyl)amino]-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide | 2-[(6-Chloro-2-methylpyr...
- PPY A● In Stock — US warehouse, ships to EU* Item #: P287412View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-[3-(2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylpyridine-3-carboxamide
- SMILES
- CN(C)C(=O)C1=CN=CC(=C1)C2=CC3=C(NC=C3C4=CC=CC=C4OC)N=C2
- InChIKey
- GYQRHHQPEMOLKH-UHFFFAOYSA-N
- InChI
- 1S/C22H20N4O2/c1-26(2)22(27)16-8-14(10-23-11-16)15-9-18-19(13-25-21(18)24-12-15)17-6-4-5-7-20(17)28-3/h4-13H,1-3H3,(H,24,25)
- Synonyms
- 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-3-pyridinecarboxamide | 5-[3-(2-methoxyphenyl)-1H-...
- DCC-2036 (Rebastinib), Tyrosine-protein kinase ABL inhibitorCAS: 1020172-07-9 Formula: C30H28FN7O3 Molecular Weight: 553.59Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: D126373View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
- SMILES
- CC(C)(C)C1=NN(C(=C1)NC(=O)NC2=C(C=C(C=C2)OC3=CC(=NC=C3)C(=O)NC)F)C4=CC5=C(C=C4)N=CC=C5
- InChIKey
- WVXNSAVVKYZVOE-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- BDBM185674 | 4-[4-[(5-Tert-butyl-2-quinolin-6-ylpyrazol-3-yl)carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carb...
- Dasatinib(BMS-354825), Bcr/Abl fusion proteinSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: D125110View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
- SMILES
- CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO
- InChIKey
- ZBNZXTGUTAYRHI-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- BMS 354825 | AR-270/43507994 | Dasatinib (JAN/INN) | HMS3744C11 | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHY...
- Dasatinib (monohydrate)● In Stock — US warehouse, ships to EU* Item #: D341181View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide;hydrate
- SMILES
- CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO.O
- InChIKey
- XHXFZZNHDVTMLI-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- AM20030145 | dasatinib.H2O | A16320 | N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpy...
![N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide](https://www.aladdinsci.com/media/catalog/product/cache/6360e336b2a70951114dbd37294096ee/N/1/N183541.png)
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Frequently Asked Questions
How is the Bcr-Abl listing put together?
It draws on reported Bcr-Abl annotations within Protein Tyrosine Kinase/RTK and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Bcr-Abl modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Bcr-Abl entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Bcr-Abl compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Bcr-Abl work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Bcr-Abl compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Bcr-Abl compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.