c-Kit
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136 products
Popular Products
- Regorafenib (BAY 73-4506), Nerve growth factor receptor Trk-ACAS: 755037-03-7 EC Number: 815-051-1 PubChem CID: 11167602 Formula: C21H15ClF4N4O3 Molecular Weight: 482.82Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: R127804View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
- SMILES
- CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
- InChIKey
- FNHKPVJBJVTLMP-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- CCG-269571 | AB00076187-01 | CHEBI:68647 | 755037-03-7 , Regorafenib | AC-25075 | MFCD16038047 | Regorafenib,BAY 73-4...
- OSI-930, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of kinase insert domain receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;Inhibitor of Raf-1 proto-oncogene; serine/threonineCAS: 728033-96-3 Formula: C22H16F3N3O2S Molecular Weight: 443.45Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: O126155View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-(quinolin-4-ylmethylamino)-N-[4-(trifluoromethoxy)phenyl]thiophene-2-carboxamide
- SMILES
- C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
- InChIKey
- FGTCROZDHDSNIO-UHFFFAOYSA-N
- InChI
- 1S/C22H16F3N3O2S/c23-22(24,25)30-16-7-5-15(6-8-16)28-21(29)20-19(10-12-31-20)27-13-14-9-11-26-18-4-2-1-3-17(14)18/h1-12,27H,13H2,(H,28,29)
- Synonyms
- AKOS026750567 | BDBM50356877 | SMR004701347 | HMS3295O11 | OSI 930 | NSC800811 | NSC-800811 | CELASTROL [MI] | CHEBI:...
- Imatinib (STI571), Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of discoidin domain receptor tyrosine kinase 1;Inhibitor of discoidin domain receptor tyrosine kinase 2Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: I124963View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
- SMILES
- CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
- InChIKey
- KTUFNOKKBVMGRW-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide | CGP-57148 | ...
- Imatinib-d8CAS: 1092942-82-9 Formula: C29H23D8N7O Molecular Weight: 501.65● In Stock — US warehouse, ships to EU* Item #: I341912View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-[(2,2,3,3,5,5,6,6-octadeuterio-4-methylpiperazin-1-yl)methyl]benzamide
- SMILES
- CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
- InChIKey
- KTUFNOKKBVMGRW-AZGHYOHESA-N
- InChI
- show more
- Synonyms
- 4-{[4-Methyl(~2~H_8_)piperazin-1-yl]methyl}-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide | D...
- Tyrphostin AG 1296Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: T129775View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6,7-dimethoxy-2-phenylquinoxaline
- SMILES
- COC1=C(C=C2C(=C1)N=CC(=N2)C3=CC=CC=C3)OC
- InChIKey
- QNOXYUNHIGOWNY-UHFFFAOYSA-N
- InChI
- 1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3
- Synonyms
- AG 1296 | AS-62520 | MFCD00270913 | NCGC00163386-01 | Tyrphostin AG 1296 | IDI1_033892 | KBio2_000142 | ag1296 | AG-1...
- Lenvatinib (E7080), Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: L125518View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
- SMILES
- COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
- InChIKey
- WOSKHXYHFSIKNG-UHFFFAOYSA-N
- InChI
- 1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)
- Synonyms
- LENVATINIB [MI] | UNII-EE083865G2 | AS-16203 | LEV | NSC800781 | NSC-800781 | DB09078 | AKOS021983298 | LENVATINIB [I...
- Pazopanib, Inhibitor of colony stimulating factor 1 receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;InhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: P125184View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
- SMILES
- CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
- InChIKey
- CUIHSIWYWATEQL-UHFFFAOYSA-N
- InChI
- 1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)
- Synonyms
- 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-pyrimidin-2-yl]amino]-2-methyl-benzenesulfonamide | 5-[[4-[(2,3-d...
- Linifanib (ABT-869), Vascular endothelial growth factor receptor inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: L126993View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
- SMILES
- CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
- InChIKey
- MPVGZUGXCQEXTM-UHFFFAOYSA-N
- InChI
- 1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
- Synonyms
- A19393 | D09635 | A-741439 | FT-0696226 | LINIFANIB [INN] | NSC764237 | NSC-764237 | CCG-264767 | J-503186 | Linifani...
- Pexidartinib, Stem cell growth factor receptor inhibitorCAS: 1029044-16-3 Formula: C20H15ClF3N5 Molecular Weight: 417.81Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P171724View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine
- SMILES
- C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F
- InChIKey
- JGWRKYUXBBNENE-UHFFFAOYSA-N
- InChI
- 1S/C20H15ClF3N5/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29)
- Synonyms
- CML-261 | D11270 | PEXIDARTINIB [MI] | N-[5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluor...
- Amuvatinib (MP-470), Platelet-derived growth factor receptor alpha inhibitorCAS: 850879-09-3 Formula: C23H21N5O3S Molecular Weight: 447.52Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: M127412View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide
- SMILES
- C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6
- InChIKey
- FOFDIMHVKGYHRU-UHFFFAOYSA-N
- InChI
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- Synonyms
- N-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide | NSC754349 | NSC-75...
- Masitinib (AB1010), Platelet-derived growth factor receptor inhibitorCAS: 790299-79-5 Formula: C28H30N6OS Molecular Weight: 498.65Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: M126981View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide
- SMILES
- CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5
- InChIKey
- WJEOLQLKVOPQFV-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE | Masitinib...
- Pazopanib HCl (GW786034 HCl), Vascular endothelial growth factor receptor inhibitorCAS: 635702-64-6 Formula: C21H23N7O2S·HCl Molecular Weight: 473.98● In Stock — US warehouse, ships to EU* Item #: P129722View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride
- SMILES
- CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.Cl
- InChIKey
- MQHIQUBXFFAOMK-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- GW786034 HCl | 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydroch...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
Which compounds are listed for c-Kit?
Compounds associated with c-Kit are grouped here under the Protein Tyrosine Kinase/RTK classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does c-Kit sit within Protein Tyrosine Kinase/RTK?
c-Kit is one target listing within the Protein Tyrosine Kinase/RTK classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from c-Kit?
For compounds listed under c-Kit, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for c-Kit?
Browse the parent Protein Tyrosine Kinase/RTK listing to reach targets neighbouring c-Kit, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.