CFTR
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113 products
Popular Products
- GlyH 101, Channel blocker of CFTRCAS: 328541-79-3 Formula: C19H15Br2N3O3 Molecular Weight: 493.15Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% sum of trans and cis● In Stock — US warehouse, ships to EU* Item #: G288753View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylideneamino]-2-(naphthalen-2-ylamino)acetamide
- SMILES
- C1=CC=C2C=C(C=CC2=C1)NCC(=O)NN=CC3=CC(=C(C(=C3O)Br)O)Br
- InChIKey
- RMBDLOATEPYBSI-NUGSKGIGSA-N
- InChI
- 1S/C19H15Br2N3O3/c20-15-8-13(18(26)17(21)19(15)27)9-23-24-16(25)10-22-14-6-5-11-3-1-2-4-12(11)7-14/h1-9,22,26-27H,10H2,(H,24,25)/b23-9+
- Synonyms
- N-2-Naphthalenyl-2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]glycine hydrazide | N-(2-Naphthalenyl)-((3,5-dibromo-2...
- Glyburide, Sulfonylurea receptor 1, Kir6.2 blockerMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: G127198View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
- SMILES
- COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
- InChIKey
- ZNNLBTZKUZBEKO-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- Bastiverit | Daonil | Semi-daonil | Euglucan | Glucolon | Glibenil | glyburide | Duraglucon | Glibenclamide | Glybenc...
- CFTR(inh)-172CAS: 307510-92-5 Formula: C18H10F3NO3S2 Molecular Weight: 409.4● In Stock — US warehouse, ships to EU* Item #: C169456View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[(Z)-[4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene]methyl]benzoic acid
- SMILES
- C1=CC(=CC(=C1)N2C(=O)C(=CC3=CC=C(C=C3)C(=O)O)SC2=S)C(F)(F)F
- InChIKey
- JIMHYXZZCWVCMI-ZSOIEALJSA-N
- InChI
- 1S/C18H10F3NO3S2/c19-18(20,21)12-2-1-3-13(9-12)22-15(23)14(27-17(22)26)8-10-4-6-11(7-5-10)16(24)25/h1-9H,(H,24,25)/b14-8-
- Synonyms
- HY-16671 | CFinh-172 | EX-A2298 | 4-[4-Oxo-2-thioxo-3-(3-trifluoromethyl-phenyl)-thiazolidin-5Z)-ylidenemethyl]-benzo...
- VX-809 (Lumacaftor), Cystic fibrosis transmembrane conductance regulator stabiliserCAS: 936727-05-8 EC Number: 811-416-4 PubChem CID: 16678941 Formula: C24H18F2N2O5 Molecular Weight: 452.41Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: V127916View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[6-[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino]-3-methylpyridin-2-yl]benzoic acid
- SMILES
- CC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O
- InChIKey
- UFSKUSARDNFIRC-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 3-(6-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid | D10134 | M...
- PPQ 102● In Stock — US warehouse, ships to EU* Item #: P288838View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 12,14-dimethyl-9-(5-methylfuran-2-yl)-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
- SMILES
- CC1=CC=C(O1)C2C3=C4C(=C(N3C5=CC=CC=C5N2)C6=CC=CC=C6)C(=O)N(C(=O)N4C)C
- InChIKey
- MNOOVRNGPIWJDI-UHFFFAOYSA-N
- InChI
- 1S/C26H22N4O3/c1-15-13-14-19(33-15)21-24-23-20(25(31)29(3)26(32)28(23)2)22(16-9-5-4-6-10-16)30(24)18-12-8-7-11-17(18)27-21/h4-14,21,27H,1-3H3
- Synonyms
- 7,9-dimethyl-6-(5-methylfuran-2-yl)-11-phenyl-5,6-dihydropyrimido[4',5':3,4]pyrrolo[1,2-a]quinoxaline-8,10(7H,9H)-dio...
- PG 01, Activator of CFTRCAS: 853138-65-5 EC Number: 684-968-5 PubChem CID: 4695397 Formula: C28H29N3O2 Molecular Weight: 439.55Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)● In Stock — US warehouse, ships to EU* Item #: P286576View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[[2-(1H-indol-3-yl)acetyl]-methylamino]-2-phenyl-N-(4-propan-2-ylphenyl)acetamide
- SMILES
- CC(C)C1=CC=C(C=C1)NC(=O)C(C2=CC=CC=C2)N(C)C(=O)CC3=CNC4=CC=CC=C43
- InChIKey
- PQAYCXMQTUEDRD-UHFFFAOYSA-N
- InChI
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- Synonyms
- 2-[[2-(1H-indol-3-yl)acetyl]-methylamino]-2-phenyl-N-(4-propan-2-ylphenyl)acetamide | 2-[(2-1H-indol-3-yl-acetyl)-met...
- Ataluren (PTC124), 80S Ribosome modulatorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: P127355View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
- SMILES
- C1=CC=C(C(=C1)C2=NC(=NO2)C3=CC(=CC=C3)C(=O)O)F
- InChIKey
- OOUGLTULBSNHNF-UHFFFAOYSA-N
- InChI
- 1S/C15H9FN2O3/c16-12-7-2-1-6-11(12)14-17-13(18-21-14)9-4-3-5-10(8-9)15(19)20/h1-8H,(H,19,20)
- Synonyms
- (Z)-4-oxo-4-((4-phenylthiazol-2(3H)-ylidene)amino)butanoic acid | Ataluren(ptc124) | BCP01756 | HMS3656H20 | PTC124;3...
- IOWH032, Cystic fibrosis transmembrane conductance regulator inhibitorCAS: 1191252-49-9 Formula: C22H15Br2N3O4 Molecular Weight: 545.18● In Stock — US warehouse, ships to EU* Item #: I129648View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-(3,5-dibromo-4-hydroxyphenyl)-N-[(4-phenoxyphenyl)methyl]-1,2,4-oxadiazole-5-carboxamide
- SMILES
- C1=CC=C(C=C1)OC2=CC=C(C=C2)CNC(=O)C3=NC(=NO3)C4=CC(=C(C(=C4)Br)O)Br
- InChIKey
- DSFNLJXHXBIKDS-UHFFFAOYSA-N
- InChI
- 1S/C22H15Br2N3O4/c23-17-10-14(11-18(24)19(17)28)20-26-22(31-27-20)21(29)25-12-13-6-8-16(9-7-13)30-15-4-2-1-3-5-15/h1-11,28H,12H2,(H,25,29)
- Synonyms
- LY-110,140 hydrochloride | Q27271180 | UNII-8Y3GDT6YWV | 3-(3,5-dibromo-4-hydroxyphenyl)-N-(4-phenoxybenzyl)-1,2,4-ox...
- VRT-532Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%● In Stock — US warehouse, ships to EU* Item #: V351008View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-methyl-2-(3-phenyl-1H-pyrazol-5-yl)phenol
- SMILES
- CC1=CC(=C(C=C1)O)C2=CC(=NN2)C3=CC=CC=C3
- InChIKey
- AQWKVJFRGORALM-UHFFFAOYSA-N
- InChI
- 1S/C16H14N2O/c1-11-7-8-16(19)13(9-11)15-10-14(17-18-15)12-5-3-2-4-6-12/h2-10,19H,1H3,(H,17,18)
- Synonyms
- 4-methyl-2-(3-phenyl-1H-pyrazol-5-yl)phenol | 4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol | VRT 532 | VRT532
- KM 11060Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)● In Stock — US warehouse, ships to EU* Item #: K286877View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-chloro-4-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]quinoline
- SMILES
- C1CN(CCN1C2=C3C=CC(=CC3=NC=C2)Cl)S(=O)(=O)C4=CC=C(C=C4)Cl
- InChIKey
- GIEHIZKCIZLXLF-UHFFFAOYSA-N
- InChI
- 1S/C19H17Cl2N3O2S/c20-14-1-4-16(5-2-14)27(25,26)24-11-9-23(10-12-24)19-7-8-22-18-13-15(21)3-6-17(18)19/h1-8,13H,9-12H2
- Synonyms
- Z31097998 | CCG-44815 | Oprea1_790000 | 7-chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazin-1-yl}quinoline | AS-55981 |...
- Ivacaftor (VX-770), Activator of CFTRMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: V127056View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
- SMILES
- CC(C)(C)C1=CC(=C(C=C1NC(=O)C2=CNC3=CC=CC=C3C2=O)O)C(C)(C)C
- InChIKey
- PURKAOJPTOLRMP-UHFFFAOYSA-N
- InChI
- 1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)
- Synonyms
- 1134822-00-6 | GTPL1681 | N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-4-oxo-1,4-dihydroquinoline-3-carboxamide | 3...
- Astressin 2B◐ .Made to order · 8–12 wks Item #: A287468View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- show more
- InChIKey
- IVIBPRHVUKMKSX-XJYAKNQHSA-N
- InChI
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- Synonyms
- astressin-2B | Cyclo(31-34)(Phe(11),His(12),CMeLeu(13,39),Nle(17),Glu(31),Lys(34)) Ac-sauvagine (8-40) | cyclo(31-34)...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
Which compounds are listed for CFTR?
Compounds associated with CFTR are grouped here under the Membrane Transporter/Ion Channel classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does CFTR sit within Membrane Transporter/Ion Channel?
CFTR is one target listing within the Membrane Transporter/Ion Channel classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from CFTR?
For compounds listed under CFTR, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for CFTR?
Browse the parent Membrane Transporter/Ion Channel listing to reach targets neighbouring CFTR, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.