CRISPR/Cas9

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  1. SCR7 pyrazine
    CAS: 14892-97-8 PubChem CID: 10688007 Formula: C18H12N4OS Molecular Weight: 332.38
    ● In Stock — US warehouse, ships to EU* Item #: S287286
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    IUPAC Name
    6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one
    SMILES
    C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
    InChIKey
    GSRTWXVBHGOUBU-UHFFFAOYSA-N
    InChI
    1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24)
    Synonyms
    SCR7 pyrazine, >=98% (HPLC) | HY-107845 | Z3244609139 | 6,7-diphenyl-2-thioxo-2,3-dihydropteridin-4(1H)-one | AKOS025...
  2. Nocodazole
    CAS: 31430-18-9 EC Number: 250-626-5 Formula: C14H11N3O3S Molecular Weight: 301.32
    ● In Stock — US warehouse, ships to EU* Item #: N129755
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    IUPAC Name
    methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
    SMILES
    COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
    InChIKey
    KYRVNWMVYQXFEU-UHFFFAOYSA-N
    InChI
    1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)
    Synonyms
    HMS587E01 | Methyl (5-(2-thienylcarbonyl))-1H-benzimidazole-2-ylcarbamate | MLS001164242 | DTXCID7011800 | KBio3_0027...
  3. L-755,507, Agonist of β 3-adrenoceptor
    CAS: 159182-43-1 Formula: C30H40N4O6S Molecular Weight: 584.73
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: L288431
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    IUPAC Name
    1-hexyl-3-[4-[[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]sulfamoyl]phenyl]urea
    SMILES
    CCCCCCNC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)CCNCC(COC3=CC=C(C=C3)O)O
    InChIKey
    NYYJKMXNVNFOFQ-MHZLTWQESA-N
    InChI
    1S/C30H40N4O6S/c1-2-3-4-5-19-32-30(37)33-24-10-16-29(17-11-24)41(38,39)34-25-8-6-23(7-9-25)18-20-31-21-27(36)22-40-28-14-12-26(35)13-15-28/h6-17,27,31show more
    Synonyms
    L755507 | HMS3677M07 | 4-(3-Hexyl-ureido)-N-(4-{2-[2-hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenyl)-benzen...
  4. NU7441 (KU-57788), Inhibitor of protein kinase; DNA-activated; catalytic subunit
    CAS: 503468-95-9 Formula: C25H19NO3S Molecular Weight: 413.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: K126842
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    IUPAC Name
    8-dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one
    SMILES
    C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56
    InChIKey
    JAMULYFATHSZJM-UHFFFAOYSA-N
    InChI
    1S/C25H19NO3S/c27-21-15-23(26-11-13-28-14-12-26)29-24-17(6-3-9-20(21)24)19-8-4-7-18-16-5-1-2-10-22(16)30-25(18)19/h1-10,15H,11-14H2
    Synonyms
    SCHEMBL8246439 | A6548 | NU7441 | NU-7441 | SMR004702957 | MLS006011188 | NU-7441 (KU-57788) | NU7441 (KU-57788) | 8-...
  5. 3′-Azido-3′-deoxythymidine, Human immunodeficiency virus type 1 reverse transcriptase inhibitor
    CAS: 30516-87-1 EC Number: 623-849-4 Formula: C10H13N5O4 Molecular Weight: 267.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: A122924
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    IUPAC Name
    1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
    SMILES
    CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]
    InChIKey
    HBOMLICNUCNMMY-XLPZGREQSA-N
    InChI
    1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
    Synonyms
    3'-Azido-2',3'-Dideoxythymidine | 4B9XT59T7S | DTXSID8020127 | Racemic Liposomal AZT | Aziodothymidine | HSDB 6515 | ...
  6. 4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamide
    CAS: 312756-74-4 Formula: C20H16Br2N2O3S Molecular Weight: 524.23
    ● In Stock — US warehouse, ships to EU* Item #: B137570
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    IUPAC Name
    3-(benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide
    SMILES
    C1=CC=C(C=C1)CNS(=O)(=O)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)Br)Br
    InChIKey
    SWKAVEUTKGKHSR-UHFFFAOYSA-N
    InChI
    1S/C20H16Br2N2O3S/c21-16-7-9-17(10-8-16)24-20(25)15-6-11-18(22)19(12-15)28(26,27)23-13-14-4-2-1-3-5-14/h1-12,23H,13H2,(H,24,25)
    Synonyms
    3-[(benzylamino)sulfonyl]-4-bromo-N-(4-bromophenyl)benzamide | AC-35367 | 3-(N-Benzylsulfamoyl)-4-bromo-N-(4-bromophe...
  7. 3′-Azido-3′-deoxythymidine, Human immunodeficiency virus type 1 reverse transcriptase inhibitor
    CAS: 30516-87-1 EC Number: 623-849-4 Formula: C10H13N5O4 Molecular Weight: 267.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: A423162
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    Technical Identifiers
    IUPAC Name
    1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
    SMILES
    CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]
    InChIKey
    HBOMLICNUCNMMY-XLPZGREQSA-N
    InChI
    1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
    Synonyms
    zidovudine|Azidothymidine|30516-87-1|3'-Azido-3'-deoxythymidine|Retrovir|AZT|Zidovudinum|Thymidine, 3'-azido-3'-deoxy...
  8. 4-Bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]benzamide
    CAS: 312756-74-4 EC Number: 683-710-9 Formula: C20H16Br2N2O3S Molecular Weight: 524.23
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: B423223
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    Technical Identifiers
    IUPAC Name
    3-(benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide
    SMILES
    C1=CC=C(C=C1)CNS(=O)(=O)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)Br)Br
    InChIKey
    SWKAVEUTKGKHSR-UHFFFAOYSA-N
    InChI
    1S/C20H16Br2N2O3S/c21-16-7-9-17(10-8-16)24-20(25)15-6-11-18(22)19(12-15)28(26,27)23-13-14-4-2-1-3-5-14/h1-12,23H,13H2,(H,24,25)
    Synonyms
    3-[(benzylamino)sulfonyl]-4-bromo-N-(4-bromophenyl)benzamide | AC-35367 | 3-(N-Benzylsulfamoyl)-4-bromo-N-(4-bromophe...
  9. BRD0539
    CAS: 1403838-79-8 Formula: C25H25FN2O3S Molecular Weight: 452.54
    ◐ .Made to order · 8–12 wks Item #: B414216
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    IUPAC Name
    [(3aR,4R,9bR)-8-(2-fluorophenyl)-1-(4-methylphenyl)sulfonyl-2,3,3a,4,5,9b-hexahydropyrrolo[3,2-c]quinolin-4-yl]methanol
    SMILES
    CC1=CC=C(C=C1)S(=O)(=O)N2CCC3C2C4=C(C=CC(=C4)C5=CC=CC=C5F)NC3CO
    InChIKey
    CZOIXFMISSBIJL-DCEDVJGZSA-N
    InChI
    1S/C25H25FN2O3S/c1-16-6-9-18(10-7-16)32(30,31)28-13-12-20-24(15-29)27-23-11-8-17(14-21(23)25(20)28)19-4-2-3-5-22(19)26/h2-11,14,20,24-25,27,29H,12-13,show more
    Synonyms
    1H-​Pyrrolo[3,​2-​c]​quinoline-​4-​methanol,8-​(2-​fluorophenyl)​-​2,​3,​3a,​4,​5,​9b-​hexahydro-​1-​[(4-​methylphenyl)...
  10. Brefeldin A
    CAS: 20350-15-6 EC Number: 606-528-3 Formula: C16H24O4 Molecular Weight: 280.36
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC) from Penicillium brefeldianum
    ● In Stock — US warehouse, ships to EU* Item #: B102375
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    IUPAC Name
    (1R,2R,3E,7S,11E,13S,15S)-2,15-dihydroxy-7-methyl-6-oxabicyclo[11.3.0]hexadeca-3,11-dien-5-one
    SMILES
    CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O
    InChIKey
    KQNZDYYTLMIZCT-KQPMLPITSA-N
    InChI
    1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3/b6-4+,8-7+/t11-,12+,13-,14+,15+/m0/s1
    Synonyms
    BFA | BFA | MLS002701937 | s7046 | Decumbin | 4H-Cyclopent(f)oxacyclotridecin-4-one, 1,6,7,8,9,11a-beta,12,13,14,14a-...
  11. L-755,507, Agonist of β 3-adrenoceptor
    CAS: 159182-43-1 Formula: C30H40N4O6S Molecular Weight: 584.73
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: L421904
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    Technical Identifiers
    IUPAC Name
    1-hexyl-3-[4-[[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]sulfamoyl]phenyl]urea
    SMILES
    CCCCCCNC(=O)NC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)CCNCC(COC3=CC=C(C=C3)O)O
    InChIKey
    NYYJKMXNVNFOFQ-MHZLTWQESA-N
    InChI
    1S/C30H40N4O6S/c1-2-3-4-5-19-32-30(37)33-24-10-16-29(17-11-24)41(38,39)34-25-8-6-23(7-9-25)18-20-31-21-27(36)22-40-28-14-12-26(35)13-15-28/h6-17,27,31show more
    Synonyms
    L755507 | HMS3677M07 | 4-(3-Hexyl-ureido)-N-(4-{2-[2-hydroxy-3-(4-hydroxy-phenoxy)-propylamino]-ethyl}-phenyl)-benzen...
  12. SCR7 pyrazine
    CAS: 14892-97-8 EC Number: 998-871-3 PubChem CID: 10688007 Formula: C18H12N4OS Molecular Weight: 332.38
    10mM in DMSO
    ● In Stock — US warehouse, ships to EU* Item #: S421744
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    Technical Identifiers
    IUPAC Name
    6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one
    SMILES
    C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
    InChIKey
    GSRTWXVBHGOUBU-UHFFFAOYSA-N
    InChI
    1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24)
    Synonyms
    SCR7 pyrazine, >=98% (HPLC) | HY-107845 | Z3244609139 | 6,7-diphenyl-2-thioxo-2,3-dihydropteridin-4(1H)-one | AKOS025...
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Frequently Asked Questions

Which compounds are listed for CRISPR/Cas9?
Compounds associated with CRISPR/Cas9 are grouped here under the Cell Cycle/DNA Damage classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does CRISPR/Cas9 sit within Cell Cycle/DNA Damage?
CRISPR/Cas9 is one target listing within the Cell Cycle/DNA Damage classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from CRISPR/Cas9?
For compounds listed under CRISPR/Cas9, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for CRISPR/Cas9?
Browse the parent Cell Cycle/DNA Damage listing to reach targets neighbouring CRISPR/Cas9, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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