Ras

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  1. (R)-CE3F4
    CAS: 1593478-56-8 Formula: C11H10Br2FNO Molecular Weight: 351.01
    ◐ .Made to order · 8–12 wks Item #: R287208
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    IUPAC Name
    (2R)-5,7-dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbaldehyde
    SMILES
    CC1CCC2=C(C(=C(C=C2N1C=O)Br)F)Br
    InChIKey
    ZZLQPWXVZCPUGC-ZCFIWIBFSA-N
    InChI
    1S/C11H10Br2FNO/c1-6-2-3-7-9(15(6)5-16)4-8(12)11(14)10(7)13/h4-6H,2-3H2,1H3/t6-/m1/s1
    Synonyms
    (2R)-5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde
  2. Neoantimycin
    CAS: 22862-63-1 Formula: C36H46N2O12 Molecular Weight: 698.76
    ● In Stock — US warehouse, ships to EU* Item #: N329566
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    IUPAC Name
    N-(15-benzyl-10-butan-2-yl-14-hydroxy-7,13,13-trimethyl-2,5,9,12-tetraoxo-3-propan-2-yl-1,4,8,11-tetraoxacyclopentadec-6-yl)-3-formamido-2-hydroxybenzshow more
    SMILES
    CCC(C)C1C(=O)OC(C(C(=O)OC(C(=O)OC(C(C(C(=O)O1)(C)C)O)CC2=CC=CC=C2)C(C)C)NC(=O)C3=C(C(=CC=C3)NC=O)O)C
    InChIKey
    JIJATTFJYJZEBT-UHFFFAOYSA-N
    InChI
    1S/C36H46N2O12/c1-8-20(4)29-34(45)47-21(5)26(38-31(42)23-15-12-16-24(27(23)40)37-18-39)32(43)49-28(19(2)3)33(44)48-25(17-22-13-10-9-11-14-22)30(41)36(show more
    Synonyms
    1,4,8,11-Tetraoxacyclopentadecane, neoantimycin deriv. | 3-(Formylamino)-2-hydroxy-N-[(3S,6S,7R,10S,14R,15R)-14-hydro...
  3. ML 141
    CAS: 71203-35-5 Formula: C22H21N3O3S Molecular Weight: 407.49
    ● In Stock — US warehouse, ships to EU* Item #: M275404
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    IUPAC Name
    4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide
    SMILES
    COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=CC=C4
    InChIKey
    QBNZBMVRFYREHK-UHFFFAOYSA-N
    InChI
    1S/C22H21N3O3S/c1-28-19-11-7-17(8-12-19)22-15-21(16-5-3-2-4-6-16)24-25(22)18-9-13-20(14-10-18)29(23,26)27/h2-14,22H,15H2,1H3,(H2,23,26,27)
    Synonyms
    4-[3-(4-Methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide | 4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihy...
  4. NSC 23766
    CAS: 1177865-17-6 PubChem CID: 16759159 Formula: C24H35N7·3HCl Molecular Weight: 530.96
    ● In Stock — US warehouse, ships to EU* Item #: N129204
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    IUPAC Name
    6-N-[2-[5-(diethylamino)pentan-2-ylamino]-6-methylpyrimidin-4-yl]-2-methylquinoline-4,6-diamine;trihydrochloride
    SMILES
    CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C.Cl.Cl.Cl
    InChIKey
    CPUHORIUXPQCHW-UHFFFAOYSA-N
    InChI
    1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22;;;/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,show more
    Synonyms
    NSC23766 trihydrochloride | UNM-0000305815 | BN162673 | CCG-265031 | EX-A3156 | NSC23766 3HCl salt | NSC 23766 trihyd...
  5. Manumycin A
    CAS: 52665-74-4 PubChem CID: 6438330 Formula: C31H38N2O7 Molecular Weight: 550.64
    ◐ .Made to order · 8–12 wks Item #: M274901
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    IUPAC Name
    (2E,4E,6R)-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-show more
    SMILES
    CCCCC(C)C=C(C)C=C(C)C(=O)NC1=CC(C2C(C1=O)O2)(C=CC=CC=CC(=O)NC3=C(CCC3=O)O)O
    InChIKey
    TWWQHCKLTXDWBD-MVTGTTCWSA-N
    InChI
    1S/C31H38N2O7/c1-5-6-11-19(2)16-20(3)17-21(4)30(38)32-22-18-31(39,29-28(40-29)27(22)37)15-10-8-7-9-12-25(36)33-26-23(34)13-14-24(26)35/h7-10,12,15-19,show more
    Synonyms
    DTXSID401025744 | Manumycin A | LMFA08020185 | NCGC00163464-01 | NCGC00163464-02 | Ucfi-C | 2,4-DECADIENAMIDE, N-(5-H...
  6. Rhosin hydrochloride
    CAS: 1281870-42-5 PubChem CID: 52998412 Formula: C20H19ClN6O Molecular Weight: 394.86
    ● In Stock — US warehouse, ships to EU* Item #: R286684
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    IUPAC Name
    (2R)-2-amino-3-(1H-indol-3-yl)-N-[(E)-quinoxalin-6-ylmethylideneamino]propanamide;hydrochloride
    SMILES
    C1=CC=C2C(=C1)C(=CN2)CC(C(=O)NN=CC3=CC4=NC=CN=C4C=C3)N.Cl
    InChIKey
    SFRGBDFQSLZYLF-GRYLRVQNSA-N
    InChI
    1S/C20H18N6O.ClH/c21-16(10-14-12-24-17-4-2-1-3-15(14)17)20(27)26-25-11-13-5-6-18-19(9-13)23-8-7-22-18;/h1-9,11-12,16,24H,10,21H2,(H,26,27);1H/b25-11+;show more
    Synonyms
    D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide hydrochloride | (R,E)-2-amino-3-(1H-indol-3-yl)-N'-(quinoxalin...
  7. NSC 23766
    CAS: 733767-34-5 Formula: C24H35N7 Molecular Weight: 421.58
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ◐ .Made to order · 8–12 wks Item #: N331803
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    IUPAC Name
    6-N-[2-[5-(diethylamino)pentan-2-ylamino]-6-methylpyrimidin-4-yl]-2-methylquinoline-4,6-diamine
    SMILES
    CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C
    InChIKey
    DEFBCZWQLILOJF-UHFFFAOYSA-N
    InChI
    1S/C24H35N7/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,2show more
    Synonyms
    NSC23766 | N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4- pyrimidinyl]-2-methyl-4,6-quinolinediamine | 3-t...
  8. BMS-214662 hydrochloride
    CAS: 195981-08-9 PubChem CID: 44189294 Formula: C25H24ClN5O2S2 Molecular Weight: 526.07
    ◐ .Made to order · 8–12 wks Item #: B168288
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    IUPAC Name
    (3R)-3-benzyl-1-(1H-imidazol-5-ylmethyl)-4-thiophen-2-ylsulfonyl-3,5-dihydro-2H-1,4-benzodiazepine-7-carbonitrile;hydrochloride
    SMILES
    C1C(N(CC2=C(N1CC3=CN=CN3)C=CC(=C2)C#N)S(=O)(=O)C4=CC=CS4)CC5=CC=CC=C5.Cl
    InChIKey
    LBPFLNDUCNNGPS-GNAFDRTKSA-N
    InChI
    1S/C25H23N5O2S2.ClH/c26-13-20-8-9-24-21(11-20)15-30(34(31,32)25-7-4-10-33-25)23(12-19-5-2-1-3-6-19)17-29(24)16-22-14-27-18-28-22;/h1-11,14,18,23H,12,1show more
    Synonyms
    195981-08-9|BMS-214662 hydrochloride|(R)-1-((1H-Imidazol-4-yl)methyl)-3-benzyl-4-(thiophen-2-ylsulfonyl)-2,3,4,5-tetr...
  9. Oncrasin 1
    CAS: 75629-57-1 Formula: C16H12ClNO Molecular Weight: 269.73
    ● In Stock — US warehouse, ships to EU* Item #: O159895
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    IUPAC Name
    1-[(4-chlorophenyl)methyl]indole-3-carbaldehyde
    SMILES
    C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)C=O
    InChIKey
    ZDRQMXCSSAPUMM-UHFFFAOYSA-N
    InChI
    1S/C16H12ClNO/c17-14-7-5-12(6-8-14)9-18-10-13(11-19)15-3-1-2-4-16(15)18/h1-8,10-11H,9H2
    Synonyms
    BP-25398 | ONC-1 | N-4-chlorobenzyl-3-formylindole | FT-0734916 | HY-16662 | 1-[(4-Chlorophenyl)methyl]-1H-indole-3-c...
  10. XRP44X
    CAS: 729605-21-4 PubChem CID: 10339779 Formula: C21H21ClN4O Molecular Weight: 380.88
    ● In Stock — US warehouse, ships to EU* Item #: X342763
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    IUPAC Name
    [4-(3-chlorophenyl)piperazin-1-yl]-(5-methyl-2-phenylpyrazol-3-yl)methanone
    SMILES
    CC1=NN(C(=C1)C(=O)N2CCN(CC2)C3=CC(=CC=C3)Cl)C4=CC=CC=C4
    InChIKey
    NPHPNBGYPKBDDB-UHFFFAOYSA-N
    InChI
    1S/C21H21ClN4O/c1-16-14-20(26(23-16)18-7-3-2-4-8-18)21(27)25-12-10-24(11-13-25)19-9-5-6-17(22)15-19/h2-9,14-15H,10-13H2,1H3
    Synonyms
    Ras-Net (Elk-3) Pathway Inhibitor | Actin Assembly Inhibitor XVI | Ras Activation Inhibitor | Tubulin Polymerization ...
  11. ZCL 278
    CAS: 587841-73-4 PubChem CID: 1791111 Formula: C21H19BrClN5O4S2 Molecular Weight: 584.89
    ● In Stock — US warehouse, ships to EU* Item #: Z288200
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    IUPAC Name
    2-(4-bromo-2-chlorophenoxy)-N-[[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]carbamothioyl]acetamide
    SMILES
    CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)COC3=C(C=C(C=C3)Br)Cl)C
    InChIKey
    XKZDWYDHEBCGCG-UHFFFAOYSA-N
    InChI
    1S/C21H19BrClN5O4S2/c1-12-9-13(2)25-20(24-12)28-34(30,31)16-6-4-15(5-7-16)26-21(33)27-19(29)11-32-18-8-3-14(22)10-17(18)23/h3-10H,11H2,1-2H3,(H,24,25,show more
    Synonyms
    2-(4-Bromo-2-chlorophenoxy)-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]thioxomethyl]acetamide
  12. Lonafarnib, Protein farnesyltransferase inhibitor
    CAS: 193275-84-2 Formula: C27H31Br2ClN4O2 Molecular Weight: 638.82
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● In Stock — US warehouse, ships to EU* Item #: L125407
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    IUPAC Name
    4-[2-[4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboshow more
    SMILES
    C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N
    InChIKey
    DHMTURDWPRKSOA-RUZDIDTESA-N
    InChI
    1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11Hshow more
    Synonyms
    1-Piperidinecarboxamide, 4-(2-(4-((11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-y...
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Frequently Asked Questions

How is the Ras listing put together?
It draws on reported Ras annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Ras modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Ras entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Ras compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Ras work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Ras compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Ras compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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