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  1. TX-1123
    CAS: 157397-06-3 PubChem CID: 403661 Formula: C20H24O3 Molecular Weight: 312.4
    ◐ .Made to order · 8–12 wks Item #: T339226
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    IUPAC Name
    2-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]cyclopent-4-ene-1,3-dione
    SMILES
    CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C2C(=O)C=CC2=O
    InChIKey
    VUEUMQIBGLKJJD-UHFFFAOYSA-N
    InChI
    1S/C20H24O3/c1-19(2,3)14-10-12(9-13-16(21)7-8-17(13)22)11-15(18(14)23)20(4,5)6/h7-11,23H,1-6H3
    Synonyms
    2-((3,5-di-tert-Butyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione
  2. SU 6656, Inhibitor of aurora kinase B;Inhibitor of aurora kinase C;Inhibitor of BR serine/threonine kinase 2;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of LYN proto-oncogene; Src family tyrosine kinase;Inhibitor of SRC proto-oncogene; no
    CAS: 330161-87-0 PubChem CID: 5312137 Formula: C19H21N3O3S Molecular Weight: 371.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In Stock — US warehouse, ships to EU* Item #: S288813
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    IUPAC Name
    (3Z)-N,N-dimethyl-2-oxo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indole-5-sulfonamide
    SMILES
    CN(C)S(=O)(=O)C1=CC2=C(C=C1)NC(=O)C2=CC3=CC4=C(N3)CCCC4
    InChIKey
    LOGJQOUIVKBFGH-YBEGLDIGSA-N
    InChI
    1S/C19H21N3O3S/c1-22(2)26(24,25)14-7-8-18-15(11-14)16(19(23)21-18)10-13-9-12-5-3-4-6-17(12)20-13/h7-11,20H,3-6H2,1-2H3,(H,21,23)/b16-10-
    Synonyms
    2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide | (Z)-2-hydrox...
  3. PD-161570
    CAS: 192705-80-9 EC Number: 663-331-5 PubChem CID: 5328135 Formula: C26H35Cl2N7O Molecular Weight: 532.51
    ● In Stock — US warehouse, ships to EU* Item #: P135784
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    1-tert-butyl-3-[6-(2,6-dichlorophenyl)-2-[4-(diethylamino)butylamino]pyrido[2,3-d]pyrimidin-7-yl]urea
    SMILES
    CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=C(C=CC=C3Cl)Cl)NC(=O)NC(C)(C)C
    InChIKey
    MKVMEJKNLUWFSQ-UHFFFAOYSA-N
    InChI
    1S/C26H35Cl2N7O/c1-6-35(7-2)14-9-8-13-29-24-30-16-17-15-18(21-19(27)11-10-12-20(21)28)23(31-22(17)32-24)33-25(36)34-26(3,4)5/h10-12,15-16H,6-9,13-14H2show more
    Synonyms
    DTXSID80416145 | E79105 | HMS3678B11 | 1-tert-Butyl-3-[6-(2,6-dichlorophenyl)-2-[[4- (diethylamino)butyl]amino]pyrido...
  4. PF-477736, Inhibitor of checkpoint kinase 1;Inhibitor of checkpoint kinase 2
    CAS: 952021-60-2 Formula: C22H25N7O2 Molecular Weight: 419.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P120184
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    IUPAC Name
    (2R)-2-amino-2-cyclohexyl-N-[2-(1-methylpyrazol-4-yl)-9-oxo-3,10,11-triazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13),11-pentaen-6-yl]acetamide
    SMILES
    CN1C=C(C=N1)C2=C3C=NNC(=O)C4=C3C(=CC(=C4)NC(=O)C(C5CCCCC5)N)N2
    InChIKey
    NDEXUOWTGYUVGA-LJQANCHMSA-N
    InChI
    1S/C22H25N7O2/c1-29-11-13(9-25-29)20-16-10-24-28-21(30)15-7-14(8-17(27-20)18(15)16)26-22(31)19(23)12-5-3-2-4-6-12/h7-12,19,27H,2-6,23H2,1H3,(H,26,31)(show more
    Synonyms
    (2R)-2-amino-2-cyclohexyl-N-[2-(1-methyl-1H-pyrazol-4-yl)-9-oxo-3,10,11-triazatricyclo[6.4.1.0,4,13]trideca-1,4(13),5...
  5. PP2, Inhibitor of FYN proto-oncogene; Src family tyrosine kinase;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase
    CAS: 172889-27-9 EC Number: 878-892-3 Formula: C15H16ClN5 Molecular Weight: 301.77
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P125361
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    IUPAC Name
    1-tert-butyl-3-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-amine
    SMILES
    CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)Cl)N
    InChIKey
    PBBRWFOVCUAONR-UHFFFAOYSA-N
    InChI
    1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19)
    Synonyms
    AG 1879 | 4few | KBioGR_000458 | Q7120082 | 2zv9 | BRD-K95785537-001-10-8 | BDBM50142887 | C73316 | Oprea1_738267 | A...
  6. Scutellarein, Agonist of TAS2R39;Channel blocker of TRPM8
    CAS: 529-53-3 EC Number: 196-469-5 PubChem CID: 5281697 Formula: C15H10O6 Molecular Weight: 286.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● In Stock — US warehouse, ships to EU* Item #: S138949
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    IUPAC Name
    5,6,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
    SMILES
    C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O)O
    InChIKey
    JVXZRQGOGOXCEC-UHFFFAOYSA-N
    InChI
    1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H
    Synonyms
    AKOS015960467 | BCP07597 | GTPL12463 | P460GTI853 | Scutellarein | AS-19541 | HY-N0752 | NCGC00482644-02 | SCUTELLARE...
  7. Pelitinib, Epidermal growth factor receptor erbB1 inhibitor
    CAS: 257933-82-7 EC Number: 803-625-4 Formula: C24H23ClFN5O2 Molecular Weight: 467.92
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P125444
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    IUPAC Name
    (E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
    SMILES
    CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)F)Cl)C#N)NC(=O)C=CCN(C)C
    InChIKey
    WVUNYSQLFKLYNI-AATRIKPKSA-N
    InChI
    1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,show more
    Synonyms
    EKB-569 | Glyoxylic acid, 2-(dimethyl acetal) | (E)-N-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl...
  8. PP121, Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of epidermal growth factor receptor;Inhibitor of HCK proto-oncogene; Src family tyrosine kinase;Inhibitor of kinase insert domain receptor;Inhibitor of mechanistic target of rapamyc
    CAS: 1092788-83-4 EC Number: 686-913-0 Formula: C17H17N7 Molecular Weight: 319.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P126419
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    IUPAC Name
    1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine
    SMILES
    C1CCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CN=C5C(=C4)C=CN5)N
    InChIKey
    NVRXTLZYXZNATH-UHFFFAOYSA-N
    InChI
    1S/C17H17N7/c18-15-13-14(11-7-10-5-6-19-16(10)20-8-11)23-24(12-3-1-2-4-12)17(13)22-9-21-15/h5-9,12H,1-4H2,(H,19,20)(H2,18,21,22)
    Synonyms
    SW218262-2 | PP121 | PP-121 | 1092788-83-4 | BCP02256 | J-504558 | SB16563 | MLS001032035 | NCGC00346619-01 | AC-2846...
  9. 1NM-PP1
    CAS: 221244-14-0 PubChem CID: 5154691 Formula: C20H21N5 Molecular Weight: 331.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: P341313
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    IUPAC Name
    1-tert-butyl-3-(naphthalen-1-ylmethyl)pyrazolo[3,4-d]pyrimidin-4-amine
    SMILES
    CC(C)(C)N1C2=NC=NC(=C2C(=N1)CC3=CC=CC4=CC=CC=C43)N
    InChIKey
    GDQXJQSQYMMKRA-UHFFFAOYSA-N
    InChI
    1S/C20H21N5/c1-20(2,3)25-19-17(18(21)22-12-23-19)16(24-25)11-14-9-6-8-13-7-4-5-10-15(13)14/h4-10,12H,11H2,1-3H3,(H2,21,22,23)
    Synonyms
    MLS001065852 | SR-01000781016 | HMS3648M20 | Mutant Kinases Inhibitor II | SCHEMBL1964002 | EX-A868 | SMR000486341 | ...
  10. PRT062607 (P505-15, BIIB057) HCl
    CAS: 1370261-97-4 PubChem CID: 56948527 Formula: C19H23N9O·HCl Molecular Weight: 429.91
    ● In Stock — US warehouse, ships to EU* Item #: P129908
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    IUPAC Name
    2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[3-(triazol-2-yl)anilino]pyrimidine-5-carboxamide;hydrochloride
    SMILES
    C1CCC(C(C1)N)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)N4N=CC=N4)C(=O)N.Cl
    InChIKey
    RMNLLPXCNDZJMJ-IDVLALEDSA-N
    InChI
    1S/C19H23N9O.ClH/c20-15-6-1-2-7-16(15)26-19-22-11-14(17(21)29)18(27-19)25-12-4-3-5-13(10-12)28-23-8-9-24-28;/h3-5,8-11,15-16H,1-2,6-7,20H2,(H2,21,29)(show more
    Synonyms
    PRT062607 Hydrochloride | 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5...
  11. AD80
    CAS: 1384071-99-1 Formula: C22H19F4N7O Molecular Weight: 473.44
    ● In Stock — US warehouse, ships to EU* Item #: A275119
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    IUPAC Name
    1-[4-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea
    SMILES
    CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)N
    InChIKey
    CYORWDWRQMVGHN-UHFFFAOYSA-N
    InChI
    1S/C22H19F4N7O/c1-11(2)33-20-17(19(27)28-10-29-20)18(32-33)12-3-6-14(7-4-12)30-21(34)31-16-9-13(22(24,25)26)5-8-15(16)23/h3-11H,1-2H3,(H2,27,28,29)(H2show more
    Synonyms
    N-[4-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea
  12. Masitinib (AB1010), Platelet-derived growth factor receptor inhibitor
    CAS: 790299-79-5 Formula: C28H30N6OS Molecular Weight: 498.65
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In Stock — US warehouse, ships to EU* Item #: M126981
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    IUPAC Name
    4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide
    SMILES
    CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5
    InChIKey
    WJEOLQLKVOPQFV-UHFFFAOYSA-N
    InChI
    1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15show more
    Synonyms
    4-((4-METHYLPIPERAZIN-1-YL)METHYL)-N-(4-METHYL-3-((4-PYRIDIN-3-YL-1,3-THIAZOL-2-YL)AMINO)PHENYL)BENZAMIDE | Masitinib...
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Frequently Asked Questions

Which compounds are listed for Src?
Compounds associated with Src are grouped here under the Protein Tyrosine Kinase/RTK classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does Src sit within Protein Tyrosine Kinase/RTK?
Src is one target listing within the Protein Tyrosine Kinase/RTK classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from Src?
For compounds listed under Src, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for Src?
Browse the parent Protein Tyrosine Kinase/RTK listing to reach targets neighbouring Src, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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