CCR8 antagonist 2 - ≥99% , CAS No.2756350-98-6

CAS: 2756350-98-6 Cat. No.: C650241 Formula: C₂₃H₃₀ClN₃O₃S Molecular Weight: 464.02

GRADE & PURITY ≥99%

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

Overview

CCR8 antagonist 2 is a potent antagonist of CCR8 . CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the research of diseases mediated by CCR8 , such as cancer , and/or neuropathic pain (extracted from patent WO2022000443A1, compound 220)

Form:Solid

IC50& Target:CCR8

Specifications

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

CCR8 antagonist 2 is a potent antagonist of CCR8 . CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the research of diseases

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ANTAGONIST

Purity

≥99%

Names and Identifiers

Molecular Weight

464.02

Chemical and Physical Properties

• Solubility: DMSO : 4 mg/mL (8.62 mM; ultrasonic and warming and heat to 60°C)