cis-Tranexamic Acid - ≥95% , CAS No.1197-17-7

CAS: 1197-17-7 Cat. No.: C334305 Formula: C₈H₁₅NO₂ Molecular Weight: 157.21 EC Number: 112-434-9

GRADE & PURITY ≥95%

Synonyms

Anvitoff | Tranex | Transamin (TN) | Spectrum_001391 | Tranexamic acid (Transamin) | Cyclohexanecarboxylic acid, 4-(aminomethyl)- | trans-p-(Aminomethyl)cyclohexanecarboxylic acid | Ugurol | RP 18,429 | trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid |

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Overview

cis-Tranexamic Acid is an antifibrinolytic agent; blocks lysine binding sites of plasminogen. Hemostatic.

Specifications

Synonyms

Anvitoff | Tranex | Transamin (TN) | Spectrum_001391 | Tranexamic acid (Transamin) | Cyclohexanecarboxylic acid, 4-(aminomethyl)- | trans-p-(Aminomethyl)cyclohexanecarboxylic acid | Ugurol | RP 18,429 | trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid |

Specifications & Purity

≥95%

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 528776505
• Canonical Smiles: C1CC(CCC1CN)C(=O)O
• IUPAC Name: 4-(aminomethyl)cyclohexane-1-carboxylic acid
• InChIKey: GYDJEQRTZSCIOI-UHFFFAOYSA-N
• INCHI: 1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)
• Isomeric SMILES: C1CC(CCC1CN)C(=O)O
• Alternate CAS: 701-54-2
• Molecular Weight: 157.21
• Reaxy-Rn: 2207451
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2207451&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Amino acids
• Alternative Parents: Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: Amino acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Aliphatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as amino acids. These are organic compounds that contain at least one carboxyl group and one amino group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

PLG Tclin Plasminogen (0 Activities)

Discover Target: PLG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemical and Physical Properties

• Molecular Weight: 157.210 g/mol
• XLogP3: -2.000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 157.11 Da
• Monoisotopic Mass: 157.11 Da
• Topological Polar Surface Area: 63.300 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 139.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Qiao Yu, Baihai Su, Weifeng Zhao, Changsheng Zhao.  (2022)  Janus Self-Propelled Chitosan-Based Hydrogel Spheres for Rapid Bleeding Control.  Advanced Science,  10  (5): (2205989).  [PMID:36567271] [10.1002/advs.202205989]

2. Bitao Lu, Enling Hu, Ruiqi Xie, Kun Yu, Fei Lu, Rong Bao, Chenhui Wang, Guangqian Lan, Fangyin Dai.  (2022)  Microcluster colloidosomes for hemostat delivery into complex wounds: A platform inspired by the attack action of torpedoes.  Bioactive Materials,      [PMID:35415282] [10.1016/j.bioactmat.2022.01.002]

3. Yujie Hu, Feiyang Zhang, Jianfeng Zhou, Yi Yang, Deyi Ding, Mingzhang Li, Changming Wang, Boyong Wang, Jinlong Yu, Feng Jiang, Deng-Guang Yu, Hao Shen.  (2025)  Electrospun Tri-Layer Core-Sheath Nanofibrous Coating for Sequential Treatment of Postoperative Complications in Orthopedic Implants.  Small,      [PMID:40898688] [10.1002/smll.202505523]