Coumetarol - 10mM in DMSO , CAS No.4366-18-1

CAS: 4366-18-1 Cat. No.: C654823 Molecular Weight: 380.35 PubChem CID: 54716150

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Coumetarol (Dicumoxane) is a vitamin K antagonist.

In Vitro

Coumetarol (Dicumoxane), an oral anticoagulant, is active in both models. The vitamin K antagonist Coumetarol is effective in both models after oral treatment but inhibits the thrombus formation more strongly in the arterio-venous shunt model. Treatment with the vitamin K antagonist Coumetarol in a dose of 25 mg/kg p.o. twice daily for 2 days results in a significant reduction in thrombus weight by 50% in the venous stasis model and by 75% in the arterio-venous shunt model. In both experiments the coagulation time as measured by the Thrombotest is prolonged to the same extent. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:vitamin K

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Coumetarol (Dicumoxane) is a vitamin K antagonist.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ANTAGONIST

Names and Identifiers

• Isomeric SMILES: COCC(C1=C(C2=CC=CC=C2OC1=O)O)C3=C(C4=CC=CC=C4OC3=O)O
• PubChem CID: 54716150
• Molecular Weight: 380.35